STRINGSTRING
ACA1_351280 ACA1_351280 ACA1_100930 ACA1_100930 ACA1_011160 ACA1_011160 ACA1_374060 ACA1_374060 ACA1_096170 ACA1_096170 ACA1_322230 ACA1_322230 ACA1_129950 ACA1_129950 ACA1_051440 ACA1_051440 ACA1_051660 ACA1_051660 ACA1_164960 ACA1_164960 ACA1_164650 ACA1_164650 ACA1_377340 ACA1_377340 ACA1_188580 ACA1_188580 ACA1_177590 ACA1_177590 ACA1_178740 ACA1_178740 ACA1_061400 ACA1_061400 ACA1_065820 ACA1_065820 ACA1_368210 ACA1_368210 ACA1_368890 ACA1_368890 ACA1_015510 ACA1_015510 ACA1_063900 ACA1_063900 ACA1_064360 ACA1_064360 ACA1_166930 ACA1_166930 ACA1_394580 ACA1_394580 ACA1_201650 ACA1_201650 ACA1_198280 ACA1_198280 ACA1_184930 ACA1_184930 ACA1_012990 ACA1_012990 ACA1_282350 ACA1_282350 ACA1_182790 ACA1_182790 ACA1_331590 ACA1_331590 ACA1_081880 ACA1_081880 ACA1_396690 ACA1_396690 ACA1_331780 ACA1_331780 ACA1_071720 ACA1_071720 ACA1_170660 ACA1_170660 ACA1_171440 ACA1_171440 ACA1_376610 ACA1_376610 ACA1_173950 ACA1_173950 ACA1_288700 ACA1_288700 ACA1_170670 ACA1_170670 ACA1_004200 ACA1_004200 ACA1_288560 ACA1_288560 ACA1_110350 ACA1_110350 ACA1_174470 ACA1_174470 ACA1_018990 ACA1_018990 ACA1_289970 ACA1_289970
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACA1_3512803'5' exonuclease domain containing protein. (223 aa)
ACA1_100930DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1105 aa)
ACA1_011160Replication protein A2 family protein, putative. (298 aa)
ACA1_374060Rad51l1 protein. (248 aa)
ACA1_096170BRCT domain-containing protein. (1025 aa)
ACA1_322230UvrD/REP helicase subfamily protein. (496 aa)
ACA1_129950RECA_2 domain-containing protein. (480 aa)
ACA1_051440DNA replication helicase, putative. (848 aa)
ACA1_051660DNA repair and recombination protein RAD54B, putative. (689 aa)
ACA1_164960OBfold nucleic acid binding domain containing protein. (201 aa)
ACA1_164650ATPdependent DNA helicase, RecQ subfamily protein. (773 aa)
ACA1_377340DNA replication factor Dna2. (1101 aa)
ACA1_188580DNA repair and recombination protein RAD52, putative. (278 aa)
ACA1_177590Uncharacterized protein. (293 aa)
ACA1_178740Replication protein A subunit. (553 aa)
ACA1_061400TAN domain-containing protein. (362 aa)
ACA1_065820BRCA1 domain containing protein. (1032 aa)
ACA1_368210DNA repair protein XRCC3, putative. (403 aa)
ACA1_368890DNA repair helicase (Rad3) subfamily protein. (1026 aa)
ACA1_015510Replication factora protein 1 (Rpa1) subfamily protein. (646 aa)
ACA1_063900Rad50 subfamily protein. (1320 aa)
ACA1_064360Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (657 aa)
ACA1_166930RAD51, putative. (348 aa)
ACA1_3945803'5' exonuclease domain containing protein. (237 aa)
ACA1_201650DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. (342 aa)
ACA1_198280RECA_2 domain-containing protein. (307 aa)
ACA1_184930DNA repair and recombination protein RAD54, putative. (509 aa)
ACA1_012990ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (608 aa)
ACA1_282350ATPdependent DNA helicase, RecQ subfamily protein. (919 aa)
ACA1_182790ATPdependent DNA helicase. (753 aa)
ACA1_331590ATPdependent DNA helicase, RecQ subfamily protein. (1067 aa)
ACA1_081880WWE domain containing protein. (247 aa)
ACA1_396690ATPdependent DNA helicase ii, 70 kDa subunit (Ku70) superfamily protein. (645 aa)
ACA1_331780BRCA1 C Terminus (BRCT) domain containing protein. (972 aa)
ACA1_071720Meiotic recombinase Dmc1, putative; Belongs to the RecA family. (353 aa)
ACA1_170660UME domain-containing protein. (689 aa)
ACA1_171440UvrD/REP helicase subfamily protein. (1160 aa)
ACA1_376610DEAD/DEAH box helicase domain containing protein. (2476 aa)
ACA1_173950XPG Iregion domain containing protein. (832 aa)
ACA1_288700BRCA1 C Terminus (BRCT) domain containing protein. (645 aa)
ACA1_170670FRAP-related family protein. (583 aa)
ACA1_004200Serine-protein kinase ATR family protein; Belongs to the PI3/PI4-kinase family. (319 aa)
ACA1_288560ERCC4 domain containing protein. (728 aa)
ACA1_110350BRCA2 repeat-containing protein. (1827 aa)
ACA1_174470DUF1767 domain-containing protein. (708 aa)
ACA1_018990Subunit of DNA polymerase II. (1617 aa)
ACA1_289970FHA domain containing protein. (689 aa)
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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