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ACA1_351280 ACA1_351280 ACA1_100930 ACA1_100930 ACA1_011160 ACA1_011160 ACA1_374060 ACA1_374060 ACA1_129950 ACA1_129950 ACA1_051440 ACA1_051440 ACA1_164960 ACA1_164960 ACA1_377340 ACA1_377340 ACA1_188580 ACA1_188580 ACA1_178740 ACA1_178740 ACA1_368210 ACA1_368210 ACA1_015510 ACA1_015510 ACA1_166930 ACA1_166930 ACA1_394580 ACA1_394580 ACA1_198280 ACA1_198280 ACA1_071720 ACA1_071720 ACA1_376610 ACA1_376610 ACA1_173950 ACA1_173950 ACA1_288560 ACA1_288560 ACA1_110350 ACA1_110350 ACA1_174470 ACA1_174470
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACA1_3512803'5' exonuclease domain containing protein. (223 aa)
ACA1_100930DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1105 aa)
ACA1_011160Replication protein A2 family protein, putative. (298 aa)
ACA1_374060Rad51l1 protein. (248 aa)
ACA1_129950RECA_2 domain-containing protein. (480 aa)
ACA1_051440DNA replication helicase, putative. (848 aa)
ACA1_164960OBfold nucleic acid binding domain containing protein. (201 aa)
ACA1_377340DNA replication factor Dna2. (1101 aa)
ACA1_188580DNA repair and recombination protein RAD52, putative. (278 aa)
ACA1_178740Replication protein A subunit. (553 aa)
ACA1_368210DNA repair protein XRCC3, putative. (403 aa)
ACA1_015510Replication factora protein 1 (Rpa1) subfamily protein. (646 aa)
ACA1_166930RAD51, putative. (348 aa)
ACA1_3945803'5' exonuclease domain containing protein. (237 aa)
ACA1_198280RECA_2 domain-containing protein. (307 aa)
ACA1_071720Meiotic recombinase Dmc1, putative; Belongs to the RecA family. (353 aa)
ACA1_376610DEAD/DEAH box helicase domain containing protein. (2476 aa)
ACA1_173950XPG Iregion domain containing protein. (832 aa)
ACA1_288560ERCC4 domain containing protein. (728 aa)
ACA1_110350BRCA2 repeat-containing protein. (1827 aa)
ACA1_174470DUF1767 domain-containing protein. (708 aa)
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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