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ACA1_145060 ACA1_145060 ACA1_388180 ACA1_388180 ACA1_388480 ACA1_388480 ACA1_258330 ACA1_258330 ACA1_101560 ACA1_101560 ACA1_101580 ACA1_101580 ACA1_373890 ACA1_373890 ACA1_362780 ACA1_362780 ACA1_092650 ACA1_092650 ACA1_093450 ACA1_093450 ACA1_101470 ACA1_101470 ACA1_100020 ACA1_100020 ACA1_097370 ACA1_097370 ACA1_246780 ACA1_246780 ACA1_359260 ACA1_359260 ACA1_093470 ACA1_093470 ACA1_359270 ACA1_359270 ACA1_364700 ACA1_364700 ACA1_076370 ACA1_076370 ACA1_038380 ACA1_038380 ACA1_366460 ACA1_366460 ACA1_325150 ACA1_325150 ACA1_192940 ACA1_192940 ACA1_220780 ACA1_220780 ACA1_328920 ACA1_328920 ACA1_328780 ACA1_328780 ACA1_325160 ACA1_325160 ACA1_275770 ACA1_275770 ACA1_223930 ACA1_223930 ACA1_203630 ACA1_203630 ACA1_203680 ACA1_203680 ACA1_219820 ACA1_219820 ACA1_202120 ACA1_202120 ACA1_087310 ACA1_087310 ACA1_382590 ACA1_382590 ACA1_336910 ACA1_336910 ACA1_043350 ACA1_043350 ACA1_382900 ACA1_382900 ACA1_204480 ACA1_204480 ACA1_059990 ACA1_059990 ACA1_064560 ACA1_064560 ACA1_066000 ACA1_066000 ACA1_063340 ACA1_063340 ACA1_382660 ACA1_382660 ACA1_060500 ACA1_060500 ACA1_383740 ACA1_383740 ACA1_248540 ACA1_248540 ACA1_066130 ACA1_066130 ACA1_062350 ACA1_062350 ACA1_062920 ACA1_062920 ACA1_155820 ACA1_155820 ACA1_369250 ACA1_369250 ACA1_151070 ACA1_151070 ACA1_136790 ACA1_136790 ACA1_301260 ACA1_301260 ACA1_328900 ACA1_328900 ACA1_368170 ACA1_368170 ACA1_265330 ACA1_265330 ACA1_267290 ACA1_267290 ACA1_393920 ACA1_393920 ACA1_133470 ACA1_133470 ACA1_031970 ACA1_031970 ACA1_323500 ACA1_323500 ACA1_053320 ACA1_053320 ACA1_338800 ACA1_338800 ACA1_054700 ACA1_054700 ACA1_114420 ACA1_114420 ACA1_279210 ACA1_279210 ACA1_277350 ACA1_277350 ACA1_278330 ACA1_278330 ACA1_195000 ACA1_195000 ACA1_206070 ACA1_206070 ACA1_284100 ACA1_284100 ACA1_053340 ACA1_053340 ACA1_227760 ACA1_227760 ACA1_325540 ACA1_325540 ACA1_284850 ACA1_284850 ACA1_184340 ACA1_184340 ACA1_255700 ACA1_255700 ACA1_386360 ACA1_386360 ACA1_255190 ACA1_255190 ACA1_384340 ACA1_384340 ACA1_396950 ACA1_396950 ACA1_036400 ACA1_036400 ACA1_396150 ACA1_396150 ACA1_142240 ACA1_142240 ACA1_357160 ACA1_357160 ACA1_149260 ACA1_149260 ACA1_254740 ACA1_254740 ACA1_068410 ACA1_068410 ACA1_396540 ACA1_396540 ACA1_068990 ACA1_068990 ACA1_069090 ACA1_069090 ACA1_036220 ACA1_036220 ACA1_036330 ACA1_036330 ACA1_070500 ACA1_070500 ACA1_080680 ACA1_080680 ACA1_075020 ACA1_075020 ACA1_068070 ACA1_068070 ACA1_360620 ACA1_360620 ACA1_361180 ACA1_361180 ACA1_342400 ACA1_342400 ACA1_072100 ACA1_072100 ACA1_169050 ACA1_169050 ACA1_376580 ACA1_376580 ACA1_376740 ACA1_376740 ACA1_074650 ACA1_074650 ACA1_075010 ACA1_075010 ACA1_144090 ACA1_144090 ACA1_175600 ACA1_175600 ACA1_287240 ACA1_287240 ACA1_168940 ACA1_168940 ACA1_333210 ACA1_333210 ACA1_174340 ACA1_174340 ACA1_296340 ACA1_296340 ACA1_296920 ACA1_296920
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACA1_145060Actin subfamily protein. (198 aa)
ACA1_388180Actin-1, putative; Belongs to the actin family. (317 aa)
ACA1_388480Cofilin/tropomyosin-type actin-binding protein; Belongs to the actin-binding proteins ADF family. (248 aa)
ACA1_25833014_3_3 domain-containing protein; Belongs to the 14-3-3 family. (260 aa)
ACA1_10156066-kDa stress protein p66, putative. (664 aa)
ACA1_101580Actininteracting protein, putative. (106 aa)
ACA1_373890Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (361 aa)
ACA1_362780Cofilin/tropomyosin-type actin-binding protein. (482 aa)
ACA1_092650Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (460 aa)
ACA1_093450Tubulin/FtsZ family, GTPase domain containing protein; Belongs to the tubulin family. (616 aa)
ACA1_101470Dynactin 4 isoform 2, putative. (204 aa)
ACA1_100020Uncharacterized protein. (219 aa)
ACA1_097370Ras subfamily protein. (174 aa)
ACA1_246780Ras subfamily protein. (191 aa)
ACA1_359260Actin-1, putative; Belongs to the actin family. (162 aa)
ACA1_093470ADPribosylation factor subfamily protein. (302 aa)
ACA1_359270RAB family member (Rab7), putative. (206 aa)
ACA1_364700Ras family protein. (217 aa)
ACA1_076370Profilin; Belongs to the profilin family. (123 aa)
ACA1_038380Dynein light chain. (89 aa)
ACA1_366460Dynactin subunit 6, putative. (188 aa)
ACA1_325150Rab7/RabGfamily small GTPase. (205 aa)
ACA1_192940Actin subfamily protein; Belongs to the actin family. (366 aa)
ACA1_220780Urease; In the C-terminal section; belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. (836 aa)
ACA1_328920Actin, putative. (142 aa)
ACA1_328780Actin subfamily protein; Belongs to the actin family. (299 aa)
ACA1_325160Rab7/RabGfamily small GTPase. (186 aa)
ACA1_275770Twinfilin, putative. (343 aa)
ACA1_223930Actin subfamily protein; Belongs to the actin family. (412 aa)
ACA1_203630Uncharacterized protein. (1161 aa)
ACA1_203680Cofilin/tropomyosin-type actin-binding protein. (172 aa)
ACA1_219820Actin-1, putative. (375 aa)
ACA1_202120Tubulin/FtsZ family, GTPase domain containing protein; Belongs to the tubulin family. (356 aa)
ACA1_087310Ras subfamily protein. (143 aa)
ACA1_382590Actin subfamily protein; Belongs to the actin family. (477 aa)
ACA1_336910Actin subfamily protein; Belongs to the actin family. (504 aa)
ACA1_043350F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (301 aa)
ACA1_382900ADPribosylation factor, putative; Belongs to the small GTPase superfamily. Arf family. (186 aa)
ACA1_204480Tubulin/FtsZ family, GTPase domain containing protein; Belongs to the tubulin family. (363 aa)
ACA1_059990Actine, putative; Belongs to the actin family. (310 aa)
ACA1_064560Uncharacterized protein. (623 aa)
ACA1_066000Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (293 aa)
ACA1_063340Dynein intermediate chain, cytosolic, putative. (644 aa)
ACA1_382660Actin subfamily protein; Belongs to the actin family. (427 aa)
ACA1_060500Actin, putative; Belongs to the actin family. (393 aa)
ACA1_383740GTPbinding protein YPTC5, putative. (197 aa)
ACA1_248540Dynein light chain tctextype, putative. (102 aa)
ACA1_066130Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)
ACA1_062350Glia maturation factor family protein; Belongs to the actin-binding proteins ADF family. GMF subfamily. (148 aa)
ACA1_062920Rab1, putative. (179 aa)
ACA1_155820Tubulin/FtsZ family, GTPase domain containing protein; Belongs to the tubulin family. (358 aa)
ACA1_369250Dynactin 50 kDa subunit. (411 aa)
ACA1_151070Actin subfamily protein; Belongs to the actin family. (283 aa)
ACA1_136790Tubulin/FtsZ family, GTPase domain containing protein; Belongs to the tubulin family. (601 aa)
ACA1_301260WD repeatcontaining protein 1, putative. (471 aa)
ACA1_328900Actin-1, putative; Belongs to the actin family. (244 aa)
ACA1_368170Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (127 aa)
ACA1_265330F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (280 aa)
ACA1_267290Uncharacterized protein. (522 aa)
ACA1_393920Tubulin/FtsZ family, GTPase domain containing protein. (461 aa)
ACA1_133470Actin subfamily protein; Belongs to the actin family. (470 aa)
ACA1_031970Actin subfamily protein; Belongs to the actin family. (311 aa)
ACA1_323500p21Rho-binding domain containing protein. (422 aa)
ACA1_053320Actin subfamily protein; Belongs to the actin family. (291 aa)
ACA1_338800Tubulin/FtsZ family, GTPase domain containing protein. (421 aa)
ACA1_054700Ras subfamily protein. (94 aa)
ACA1_114420F-box domain-containing protein. (454 aa)
ACA1_279210Fbox domain containing protein. (336 aa)
ACA1_277350P53 inducible protein. (1439 aa)
ACA1_278330WH1 domain containing protein. (345 aa)
ACA1_195000CAPGly domain containing protein. (1481 aa)
ACA1_206070Ras subfamily protein. (252 aa)
ACA1_284100F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (56 aa)
ACA1_053340Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (464 aa)
ACA1_227760Ras subfamily protein. (126 aa)
ACA1_325540Tubulin/FtsZ family, GTPase domain containing protein; Belongs to the tubulin family. (600 aa)
ACA1_284850Actin1; Belongs to the actin family. (569 aa)
ACA1_184340Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (421 aa)
ACA1_255700ADF-H domain-containing protein. (182 aa)
ACA1_386360WH2 domain-containing protein. (387 aa)
ACA1_255190Kinesin motor domain containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (819 aa)
ACA1_384340Ras subfamily protein. (207 aa)
ACA1_396950Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)
ACA1_036400Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (130 aa)
ACA1_396150Dynein heavy chain protein. (4479 aa)
ACA1_142240Actin subfamily protein; Belongs to the actin family. (839 aa)
ACA1_357160Actin subfamily protein; Belongs to the actin family. (559 aa)
ACA1_149260Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (160 aa)
ACA1_254740Actin subfamily protein; Belongs to the actin family. (368 aa)
ACA1_068410ADPribosylation factor subfamily protein. (469 aa)
ACA1_396540Actinrelated protein 3, putative; Belongs to the actin family. (428 aa)
ACA1_068990Beta actin, putative; Belongs to the actin family. (364 aa)
ACA1_069090ADF-H domain-containing protein. (177 aa)
ACA1_036220Uncharacterized protein. (78 aa)
ACA1_036330Centractin, putative; Belongs to the actin family. (381 aa)
ACA1_070500Ras subfamily protein. (211 aa)
ACA1_080680Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (481 aa)
ACA1_075020Rab7, putative. (200 aa)
ACA1_068070Small GTPbinding ADP-ribosylation factor; Belongs to the small GTPase superfamily. Arf family. (227 aa)
ACA1_360620Ras subfamily protein. (313 aa)
ACA1_361180Actin subfamily protein; Belongs to the actin family. (385 aa)
ACA1_342400Tubulin/FtsZ family, GTPase domain containing protein; Belongs to the tubulin family. (467 aa)
ACA1_072100Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (297 aa)
ACA1_169050Profilin; Belongs to the profilin family. (134 aa)
ACA1_376580Ras subfamily protein. (181 aa)
ACA1_376740Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (461 aa)
ACA1_074650Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (388 aa)
ACA1_075010Ras family protein. (187 aa)
ACA1_144090WH2 motif domain containing protein. (443 aa)
ACA1_175600Uncharacterized protein. (441 aa)
ACA1_287240WH1 domain containing protein. (194 aa)
ACA1_168940Uncharacterized protein. (422 aa)
ACA1_333210F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (277 aa)
ACA1_174340Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (388 aa)
ACA1_296340Actophorin, putative; Belongs to the actin-binding proteins ADF family. (138 aa)
ACA1_296920Adenylyl cyclase-associated protein; Belongs to the CAP family. (486 aa)
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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