STRINGSTRING
ACA1_396690 ACA1_396690 ACA1_324710 ACA1_324710 ACA1_076980 ACA1_076980 ACA1_322230 ACA1_322230 ACA1_106010 ACA1_106010 ACA1_005220 ACA1_005220 MCM7 MCM7 ACA1_321040 ACA1_321040 ACA1_077250 ACA1_077250 ACA1_051440 ACA1_051440 ACA1_276100 ACA1_276100 ACA1_164650 ACA1_164650 ACA1_377340 ACA1_377340 ACA1_378200 ACA1_378200 ACA1_164120 ACA1_164120 ACA1_177590 ACA1_177590 ACA1_382670 ACA1_382670 ACA1_058750 ACA1_058750 ACA1_177700 ACA1_177700 ACA1_090360 ACA1_090360 ACA1_248060 ACA1_248060 ACA1_208400 ACA1_208400 ACA1_368890 ACA1_368890 ACA1_206380 ACA1_206380 ACA1_138350 ACA1_138350 ACA1_267820 ACA1_267820 ACA1_267700 ACA1_267700 ACA1_201650 ACA1_201650 ACA1_237560 ACA1_237560 ACA1_114560 ACA1_114560 ACA1_266830 ACA1_266830 ACA1_052740 ACA1_052740 ACA1_012990 ACA1_012990 ACA1_282350 ACA1_282350 ACA1_182790 ACA1_182790 ACA1_281950 ACA1_281950 ACA1_159060 ACA1_159060 ACA1_331590 ACA1_331590 ACA1_360380 ACA1_360380 ACA1_251480 ACA1_251480 ACA1_071250 ACA1_071250 ACA1_173170 ACA1_173170 ACA1_356780 ACA1_356780 ACA1_171440 ACA1_171440 ACA1_376610 ACA1_376610 ACA1_171520 ACA1_171520 ACA1_175150 ACA1_175150 ACA1_399190 ACA1_399190
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACA1_396690ATPdependent DNA helicase ii, 70 kDa subunit (Ku70) superfamily protein. (645 aa)
ACA1_324710ATP-dependent DNA helicase; Belongs to the helicase family. (646 aa)
ACA1_076980RuvB-like helicase; Belongs to the RuvB family. (460 aa)
ACA1_322230UvrD/REP helicase subfamily protein. (496 aa)
ACA1_106010DNA helicase; Belongs to the MCM family. (810 aa)
ACA1_005220DNA replication licensing factor Mcm2, putative; Belongs to the MCM family. (351 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (775 aa)
ACA1_321040DNA replication licensing factor mcm3, putative; Belongs to the MCM family. (809 aa)
ACA1_077250mRNA decay factorlike protein. (1142 aa)
ACA1_051440DNA replication helicase, putative. (848 aa)
ACA1_276100ATP-dependent DNA helicase; Belongs to the helicase family. (135 aa)
ACA1_164650ATPdependent DNA helicase, RecQ subfamily protein. (773 aa)
ACA1_377340DNA replication factor Dna2. (1101 aa)
ACA1_378200ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (621 aa)
ACA1_164120Mitochondrial helicase twinkle, putative. (766 aa)
ACA1_177590Uncharacterized protein. (293 aa)
ACA1_382670DEAD/DEAH box helicase domain containing protein. (1659 aa)
ACA1_058750Nucleotide excision repair protein, putative. (696 aa)
ACA1_177700HRDC domain containing protein. (328 aa)
ACA1_090360ATP-dependent DNA helicase; Belongs to the helicase family. (265 aa)
ACA1_248060ATP-dependent DNA helicase; Belongs to the helicase family. (492 aa)
ACA1_208400DNA helicase; Belongs to the MCM family. (907 aa)
ACA1_368890DNA repair helicase (Rad3) subfamily protein. (1026 aa)
ACA1_206380MCM_OB domain-containing protein. (270 aa)
ACA1_138350Uncharacterized protein. (509 aa)
ACA1_267820ATP-dependent DNA helicase; Belongs to the helicase family. (757 aa)
ACA1_267700ATP-dependent DNA helicase; Belongs to the helicase family. (271 aa)
ACA1_201650DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. (342 aa)
ACA1_237560R3H domain containing protein. (213 aa)
ACA1_114560DNA helicase; Belongs to the MCM family. (843 aa)
ACA1_266830ATP-dependent DNA helicase; Belongs to the helicase family. (621 aa)
ACA1_052740ATP-dependent DNA helicase; Belongs to the helicase family. (668 aa)
ACA1_012990ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (608 aa)
ACA1_282350ATPdependent DNA helicase, RecQ subfamily protein. (919 aa)
ACA1_182790ATPdependent DNA helicase. (753 aa)
ACA1_281950Helicase conserved Cterminal domain containing protein. (520 aa)
ACA1_159060ATP-dependent DNA helicase; Belongs to the helicase family. (805 aa)
ACA1_331590ATPdependent DNA helicase, RecQ subfamily protein. (1067 aa)
ACA1_360380ATP-dependent DNA helicase; Belongs to the helicase family. (944 aa)
ACA1_251480BRIP1 family protein. (187 aa)
ACA1_071250DEAD box RNA helicase, putative. (2192 aa)
ACA1_173170SNF2 family Nterminal domain containing protein. (1489 aa)
ACA1_356780HD domain containing protein. (244 aa)
ACA1_171440UvrD/REP helicase subfamily protein. (1160 aa)
ACA1_376610DEAD/DEAH box helicase domain containing protein. (2476 aa)
ACA1_171520DNA repair helicase rad25 subfamily protein. (560 aa)
ACA1_175150DEAD/H (AspGlu-Ala-Asp/His) box polypeptide 11, putative. (1005 aa)
ACA1_399190ATP-dependent DNA helicase; Belongs to the helicase family. (1009 aa)
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.