STRINGSTRING
ACA1_382670 ACA1_382670 ACA1_296090 ACA1_296090 ACA1_288670 ACA1_288670 ACA1_289810 ACA1_289810 ACA1_018990 ACA1_018990 ACA1_289040 ACA1_289040 ACA1_296520 ACA1_296520 ACA1_109780 ACA1_109780 ACA1_109730 ACA1_109730 ACA1_289820 ACA1_289820 ACA1_288850 ACA1_288850 ACA1_376610 ACA1_376610 ACA1_171710 ACA1_171710 ACA1_039460 ACA1_039460 ACA1_073490 ACA1_073490 ACA1_073060 ACA1_073060 ACA1_252580 ACA1_252580 ACA1_360290 ACA1_360290 ACA1_331590 ACA1_331590 ACA1_252030 ACA1_252030 ACA1_227810 ACA1_227810 ACA1_355240 ACA1_355240 ACA1_282350 ACA1_282350 ACA1_280590 ACA1_280590 ACA1_279340 ACA1_279340 ACA1_012990 ACA1_012990 ACA1_206010 ACA1_206010 ACA1_184680 ACA1_184680 ACA1_114560 ACA1_114560 ACA1_264600 ACA1_264600 ACA1_201650 ACA1_201650 ACA1_264240 ACA1_264240 ACA1_040860 ACA1_040860 ACA1_369120 ACA1_369120 ACA1_208400 ACA1_208400 ACA1_369010 ACA1_369010 ACA1_058240 ACA1_058240 ACA1_057840 ACA1_057840 ACA1_062530 ACA1_062530 ACA1_177700 ACA1_177700 ACA1_056970 ACA1_056970 ACA1_187320 ACA1_187320 ACA1_177590 ACA1_177590 ACA1_164120 ACA1_164120 ACA1_378200 ACA1_378200 ACA1_377800 ACA1_377800 ACA1_377340 ACA1_377340 ACA1_164650 ACA1_164650 ACA1_377790 ACA1_377790 ACA1_051440 ACA1_051440 ACA1_321040 ACA1_321040 ACA1_325190 ACA1_325190 ACA1_130990 ACA1_130990 MCM7 MCM7 ACA1_320960 ACA1_320960 ACA1_005220 ACA1_005220 ACA1_106760 ACA1_106760 ACA1_106010 ACA1_106010 ACA1_238610 ACA1_238610 ACA1_341680 ACA1_341680 ACA1_349800 ACA1_349800 ACA1_097020 ACA1_097020 ACA1_092660 ACA1_092660 ACA1_258230 ACA1_258230 ACA1_136160 ACA1_136160 ACA1_344470 ACA1_344470
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACA1_382670DEAD/DEAH box helicase domain containing protein. (1659 aa)
ACA1_296090Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (453 aa)
ACA1_288670Psf1 family protein. (166 aa)
ACA1_289810CDC45 like protein. (672 aa)
ACA1_018990Subunit of DNA polymerase II. (1617 aa)
ACA1_289040DNA polymerase. (1003 aa)
ACA1_296520CUE domain containing protein. (542 aa)
ACA1_109780ATPase, AAA domain containing protein. (679 aa)
ACA1_109730Replication factor C subunit 1. (977 aa)
ACA1_289820DNA polymerase epsilon subunit B protein. (482 aa)
ACA1_288850DNA polymerase I domain containing protein. (1138 aa)
ACA1_376610DEAD/DEAH box helicase domain containing protein. (2476 aa)
ACA1_171710DNA ligase. (753 aa)
ACA1_039460Replication factor C (Activator 1) 3, putative. (303 aa)
ACA1_073490WD repeatcontaining protein. (434 aa)
ACA1_073060Uncharacterized protein. (174 aa)
ACA1_252580Replication factor C protein. (296 aa)
ACA1_360290Singlestrand binding protein family. (168 aa)
ACA1_331590ATPdependent DNA helicase, RecQ subfamily protein. (1067 aa)
ACA1_252030Nucleolar complex associated protein, putative. (855 aa)
ACA1_227810Origin recognition complex subunit 5 family protein. (468 aa)
ACA1_355240ORC4_C domain-containing protein. (281 aa)
ACA1_282350ATPdependent DNA helicase, RecQ subfamily protein. (919 aa)
ACA1_280590Poly(ADPribose) polymerase and DNA-Ligase Zn-finger region domain containing protein. (231 aa)
ACA1_279340DNA ligase. (627 aa)
ACA1_012990ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (608 aa)
ACA1_206010Proliferating cell nuclear antigen, cterminal domain containing protein. (231 aa)
ACA1_1846805'3' exonuclease, SAM domain containing protein. (1070 aa)
ACA1_114560DNA helicase; Belongs to the MCM family. (843 aa)
ACA1_264600DNA polymerase I, putative. (1123 aa)
ACA1_201650DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. (342 aa)
ACA1_264240DNA polymerase subunit Cdc27 protein. (594 aa)
ACA1_040860DNA replication factor C complex subunit 2, putative. (346 aa)
ACA1_369120Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (265 aa)
ACA1_208400DNA helicase; Belongs to the MCM family. (907 aa)
ACA1_369010DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2220 aa)
ACA1_058240WD domain, G-beta repeat-containing protein. (992 aa)
ACA1_057840Helicase, putative. (800 aa)
ACA1_062530DNA polymerase. (1352 aa)
ACA1_177700HRDC domain containing protein. (328 aa)
ACA1_056970Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (323 aa)
ACA1_187320Origin recognition complex subunit. (464 aa)
ACA1_177590Uncharacterized protein. (293 aa)
ACA1_164120Mitochondrial helicase twinkle, putative. (766 aa)
ACA1_378200ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (621 aa)
ACA1_377800ORC_WH_C domain-containing protein. (529 aa)
ACA1_377340DNA replication factor Dna2. (1101 aa)
ACA1_164650ATPdependent DNA helicase, RecQ subfamily protein. (773 aa)
ACA1_377790Origin recognition complex (Orc) subunit 3 nterminus, putative. (390 aa)
ACA1_051440DNA replication helicase, putative. (848 aa)
ACA1_321040DNA replication licensing factor mcm3, putative; Belongs to the MCM family. (809 aa)
ACA1_325190CCAATbox binding transcription factor subunit HAP3-related, putative. (96 aa)
ACA1_130990Rtf2 domain-containing protein. (301 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (775 aa)
ACA1_320960DNA primase; Belongs to the eukaryotic-type primase small subunit family. (437 aa)
ACA1_005220DNA replication licensing factor Mcm2, putative; Belongs to the MCM family. (351 aa)
ACA1_106760DNAdirected DNA polymerase subunit, putative. (256 aa)
ACA1_106010DNA helicase; Belongs to the MCM family. (810 aa)
ACA1_238610U1-type domain-containing protein. (432 aa)
ACA1_341680Uncharacterized protein. (248 aa)
ACA1_349800Timeless protein. (362 aa)
ACA1_097020DNA polymerase epsilon subunit B protein. (630 aa)
ACA1_092660Uncharacterized protein. (186 aa)
ACA1_258230DNA ligase. (667 aa)
ACA1_136160Primase zinc finger protein. (716 aa)
ACA1_344470Replication factor c subunit. (84 aa)
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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