62 items (Acanthamoeba castellanii) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

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protein homology

Your Input:
	ACA1_218440	RNA polymerase Rpb3/Rpb11 dimerization domain containing protein. (122 aa)
	ACA1_048550	Tetratricopeptide repeat domain containing protein. (1211 aa)
	ACA1_190240	Rtt106 domain-containing protein. (846 aa)
	ACA1_389090	Transcription initiation factor iid, 31kd subunit protein. (261 aa)
	MED18	Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (351 aa)
	ACA1_190750	DNAdirected RNA polymerase II subunit RPB7, putative. (153 aa)
	ACA1_191160	Small nuclear RNA activating complex, polypeptide 3, 50kDa, putative. (161 aa)
	ACA1_257030	WD domain G-beta repeat-containing protein. (725 aa)
	ACA1_261010	Transcription initiation factor IID, 18kD subunit. (296 aa)
	ACA1_050620	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (304 aa)
	ACA1_092940	Uncharacterized protein. (64 aa)
	ACA1_238410	Uncharacterized protein. (302 aa)
	ACA1_365330	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (140 aa)
	ACA1_038160	Cyclindependent kinase. (605 aa)
	ACA1_391550	Ssl1like protein. (360 aa)
	ACA1_051820	Ubiquitin family protein. (103 aa)
	ACA1_066780	Transcription initiation factor tfiid subunit 13, putative. (146 aa)
	ACA1_130580	Zinc finger, c2h2 type domain containing protein. (873 aa)
	ACA1_218610	Uncharacterized protein. (356 aa)
	ACA1_215980	Adhesion regulating molecule region protein, putative. (398 aa)
	ACA1_311970	DR1associated protein 1 (Negative cofactor 2 alpha), putative. (137 aa)
	ACA1_203930	TAF11, putative. (200 aa)
	ACA1_089850	Bromodomain domain containing protein. (1803 aa)
	ACA1_058750	Nucleotide excision repair protein, putative. (696 aa)
	ACA1_203150	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (123 aa)
	ACA1_020820	TATAbox-binding protein. (258 aa)
	ACA1_087480	Transcription factor iia, alpha/beta subunit protein. (255 aa)
	ACA1_209800	Transcription initiation factor tfiid subunit a protein. (266 aa)
	ACA1_369530	Uncharacterized protein. (371 aa)
	ACA1_369550	Uncharacterized protein. (579 aa)
	ACA1_155710	TAF6_C domain-containing protein. (462 aa)
	ACA1_234280	Uncharacterized protein. (560 aa)
	ACA1_266150	PBS lyase HEATlike repeat domain containing protein. (981 aa)
	ACA1_267310	PHDfinger domain containing protein. (468 aa)
	ACA1_234160	Transcription factor tfiib repeat domain containing protein. (303 aa)
	ACA1_262210	Poly [ADP-ribose] polymerase. (2088 aa)
	ACA1_111900	Global transcription factor, putative. (1120 aa)
	ACA1_114870	Transcription initiation factor tfiid component taf4 family protein. (778 aa)
	ACA1_194940	Uncharacterized protein. (425 aa)
	ACA1_053640	Transcription elongation factor SPT5. (1184 aa)
	ACA1_186870	Protein kinase domain containing protein. (639 aa)
	ACA1_116890	DNA-directed RNA polymerase II family protein. (151 aa)
	ACA1_225900	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (465 aa)
	ACA1_228380	DNAbinding protein SMUBP-2, putative. (799 aa)
	ACA1_228410	Chain a, 4ank: a designed ankyrin repeat protein. (619 aa)
	ACA1_158460	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1196 aa)
	ACA1_142400	Plus3 domain containing protein. (627 aa)
	ACA1_315820	Uncharacterized protein. (594 aa)
	ACA1_069620	Poly [ADP-ribose] polymerase. (2693 aa)
	ACA1_144380	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1378 aa)
	ACA1_169330	RNA polymerase Rpb5, Cterminal domain containing protein. (204 aa)
	ACA1_173170	SNF2 family Nterminal domain containing protein. (1489 aa)
	ACA1_072640	TAFII55_N domain-containing protein. (487 aa)
	ACA1_006240	RNA polymerase II subunit A Cterminal domain phosphatase SSU72, putative. (200 aa)
	ACA1_300860	Transcription factor tfiib repeat domain containing protein. (371 aa)
	ACA1_291620	DNAdirected RNA polymerase II subunit rpb4, putative. (135 aa)
	ACA1_294840	Transcription elongation factor SII, hS-II-T1 isoform 8, putative. (188 aa)
	ACA1_171520	DNA repair helicase rad25 subfamily protein. (560 aa)
	ACA1_326090	Uncharacterized protein. (421 aa)
	ACA1_174750	Zinc finger domain containing protein. (957 aa)
	ACA1_288640	Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (81 aa)
	ACA1_291010	TAF9 RNA polymerase II, TATA box binding protein (TBP)associated factor, putative. (127 aa)

Your Current Organism:

Acanthamoeba castellanii

NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACA1_006240	ACA1_020820	L8HH43	L8GWH4	RNA polymerase II subunit A Cterminal domain phosphatase SSU72, putative.	TATAbox-binding protein.	0.743
ACA1_006240	ACA1_053640	L8HH43	L8H676	RNA polymerase II subunit A Cterminal domain phosphatase SSU72, putative.	Transcription elongation factor SPT5.	0.428
ACA1_006240	ACA1_058750	L8HH43	L8GVG5	RNA polymerase II subunit A Cterminal domain phosphatase SSU72, putative.	Nucleotide excision repair protein, putative.	0.633
ACA1_006240	ACA1_116890	L8HH43	L8H6X7	RNA polymerase II subunit A Cterminal domain phosphatase SSU72, putative.	DNA-directed RNA polymerase II family protein.	0.718
ACA1_006240	ACA1_130580	L8HH43	L8GQC8	RNA polymerase II subunit A Cterminal domain phosphatase SSU72, putative.	Zinc finger, c2h2 type domain containing protein.	0.973
ACA1_006240	ACA1_144380	L8HH43	L8HFM7	RNA polymerase II subunit A Cterminal domain phosphatase SSU72, putative.	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.	0.454
ACA1_006240	ACA1_158460	L8HH43	L8HA21	RNA polymerase II subunit A Cterminal domain phosphatase SSU72, putative.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.873
ACA1_006240	ACA1_169330	L8HH43	L8HGI6	RNA polymerase II subunit A Cterminal domain phosphatase SSU72, putative.	RNA polymerase Rpb5, Cterminal domain containing protein.	0.696
ACA1_006240	ACA1_190750	L8HH43	L8GF23	RNA polymerase II subunit A Cterminal domain phosphatase SSU72, putative.	DNAdirected RNA polymerase II subunit RPB7, putative.	0.821
ACA1_006240	ACA1_203150	L8HH43	L8GW42	RNA polymerase II subunit A Cterminal domain phosphatase SSU72, putative.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.679
ACA1_006240	ACA1_218440	L8HH43	L8GQD6	RNA polymerase II subunit A Cterminal domain phosphatase SSU72, putative.	RNA polymerase Rpb3/Rpb11 dimerization domain containing protein.	0.704
ACA1_006240	ACA1_228380	L8HH43	L8H8R0	RNA polymerase II subunit A Cterminal domain phosphatase SSU72, putative.	DNAbinding protein SMUBP-2, putative.	0.400
ACA1_006240	ACA1_228410	L8HH43	L8H8W4	RNA polymerase II subunit A Cterminal domain phosphatase SSU72, putative.	Chain a, 4ank: a designed ankyrin repeat protein.	0.400
ACA1_006240	ACA1_234160	L8HH43	L8H2K8	RNA polymerase II subunit A Cterminal domain phosphatase SSU72, putative.	Transcription factor tfiib repeat domain containing protein.	0.854
ACA1_006240	ACA1_257030	L8HH43	L8GFA5	RNA polymerase II subunit A Cterminal domain phosphatase SSU72, putative.	WD domain G-beta repeat-containing protein.	0.725
ACA1_006240	ACA1_291620	L8HH43	L8HID4	RNA polymerase II subunit A Cterminal domain phosphatase SSU72, putative.	DNAdirected RNA polymerase II subunit rpb4, putative.	0.760
ACA1_006240	ACA1_294840	L8HH43	L8HIK4	RNA polymerase II subunit A Cterminal domain phosphatase SSU72, putative.	Transcription elongation factor SII, hS-II-T1 isoform 8, putative.	0.405
ACA1_006240	ACA1_300860	L8HH43	L8HHA5	RNA polymerase II subunit A Cterminal domain phosphatase SSU72, putative.	Transcription factor tfiib repeat domain containing protein.	0.854
ACA1_006240	ACA1_326090	L8HH43	L8HJE0	RNA polymerase II subunit A Cterminal domain phosphatase SSU72, putative.	Uncharacterized protein.	0.701
ACA1_020820	ACA1_006240	L8GWH4	L8HH43	TATAbox-binding protein.	RNA polymerase II subunit A Cterminal domain phosphatase SSU72, putative.	0.743

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