78 items (Acanthamoeba castellanii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ACA1_090040	RNA polymerase Rpb3/Rpb11 dimerization domain containing protein. (129 aa)
	ACA1_248230	Ribonuclease P/MRP 30 subunit. (168 aa)
	ACA1_062690	DEAD/DEAH box helicase domain containing protein. (926 aa)
	ACA1_088630	Surfeit locus protein 6 protein. (522 aa)
	ACA1_378610	DDE Tnp4 domain-containing protein. (419 aa)
	ACA1_178320	40S ribosomal protein S9. (184 aa)
	ACA1_204120	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1699 aa)
	EIF6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (244 aa)
	ACA1_204570	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (316 aa)
	ACA1_211920	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (145 aa)
	ACA1_223050	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (127 aa)
	ACA1_220320	U3 small nucleolar RNA-associated protein 15, putative. (121 aa)
	ACA1_125550	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1139 aa)
	ACA1_216450	Protein MAK16 homolog; Belongs to the MAK16 family. (285 aa)
	ACA1_320980	RNA recognition motif domain containing protein. (964 aa)
	ACA1_220510	U3 small nucleolar RNA-associated protein 15 family protein. (507 aa)
	ACA1_220130	Uncharacterized protein. (161 aa)
	ACA1_197840	Uncharacterized protein. (271 aa)
	ACA1_365100	U3 small nucleolar RNA-associated protein 6 protein. (628 aa)
	ACA1_365330	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (140 aa)
	ACA1_097570	Uncharacterized protein. (814 aa)
	ACA1_092800	TRAUB domain containing protein. (620 aa)
	ACA1_098060	Ribosomal L40e family. (128 aa)
	ACA1_025690	Fibrillarin, putative. (307 aa)
	ACA1_025710	Ubiquitin domain containing protein. (409 aa)
	ACA1_318520	RNA polymerase Rpb7 domain containing protein. (309 aa)
	ACA1_362640	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (204 aa)
	ACA1_258550	NOL1/NOP2/sun domain containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (542 aa)
	ACA1_261640	Methyltransferase domain containing protein. (818 aa)
	ACA1_260830	Uncharacterized protein. (116 aa)
	ACA1_027270	HAD_SAK_1 domain-containing protein. (241 aa)
	ACA1_180800	Nucleolar protein Nop56, putative. (517 aa)
	ACA1_109080	Nucleolar RNAassociated protein alpha isoform, putative. (457 aa)
	ACA1_332190	RNA polymerase I specific transcription initiation factor RRN3 protein. (569 aa)
	ACA1_137420	LYAR-type C2HC zinc finger protein. (243 aa)
	ACA1_232380	Thiazole biosynthesis protein ThiG, putative; Belongs to the PdxS/SNZ family. (281 aa)
	ACA1_232030	Block of proliferation 1, putative. (210 aa)
	ACA1_369810	RNA helicase. (697 aa)
	ACA1_062100	Ubiquitin B isoform 2, putative. (110 aa)
	ACA1_065980	Periodic tryptophan protein 2, putative. (940 aa)
	ACA1_065750	Uncharacterized protein. (348 aa)
	ACA1_064870	Ubiquitin domain containing protein. (90 aa)
	ACA1_361310	Methyltransferase domain containing protein. (264 aa)
	ACA1_307900	Uncharacterized protein. (664 aa)
	ACA1_360220	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (140 aa)
	ACA1_398450	Uncharacterized protein. (371 aa)
	ACA1_158170	Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family. (541 aa)
	ACA1_251460	U3 small nucleolar ribonucleoprotein component, putative. (277 aa)
	ACA1_343180	RNA polymerase Rpb3/Rpb11 dimerization domain containing protein. (350 aa)
	ACA1_183040	U3 small nucleolar ribonucleoprotein protein MPP10; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the MPP10 family. (656 aa)
	ACA1_194930	Matrix attachment region binding protein. (525 aa)
	ACA1_098430	Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family. (739 aa)
	ACA1_278930	RNA recognition motif domain containing protein. (711 aa)
	ACA1_053660	TNF receptor-associated protein 1, putative. (733 aa)
	ACA1_115430	DEAD/DEAH box helicase domain containing protein; Belongs to the DEAD box helicase family. (762 aa)
	ACA1_052390	Nucleolar protein, putative. (601 aa)
	ACA1_267200	Uncharacterized protein. (613 aa)
	ACA1_237290	Utp21 domain-containing protein. (214 aa)
	ACA1_009160	Uncharacterized protein. (216 aa)
	ACA1_201630	Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Belongs to the eukaryotic/archaeal RNase P protein component 2 family. (119 aa)
	ACA1_000210	H/ACA ribonucleoprotein complex subunit 3, putative. (64 aa)
	ACA1_290100	Krr1 family protein. (370 aa)
	ACA1_110750	RNA polymerase I large subunit. (433 aa)
	ACA1_175720	RNA recognition motif domain containing protein. (468 aa)
	ACA1_296930	Cirhin isoform 3, putative. (662 aa)
	ACA1_295790	Ubiquitin carboxyl-terminal hydrolase. (695 aa)
	ACA1_171240	Ribosomal protein L7Ae protein. (381 aa)
	ACA1_289990	Uncharacterized protein. (329 aa)
	ACA1_287860	BP28CT domain-containing protein. (2409 aa)
	ACA1_174150	RRP7 domain-containing protein. (383 aa)
	ACA1_110530	Polyubiqutin. (76 aa)
	ACA1_109800	WD domain, Gbeta repeat containing protein. (413 aa)
	ACA1_075290	rRNA pseudouridine synthase, putative. (523 aa)
	ACA1_272730	Ubiquitin carboxyl-terminal hydrolase. (916 aa)
	ACA1_300720	WD repeat domain 43 isoform 5, putative. (252 aa)
	ACA1_144400	WD repeat protein WDR3, putative. (1010 aa)
	ACA1_073360	RNA recognition motif domain containing protein. (425 aa)
	ACA1_069240	tRNA pseudouridine synthase B, putative. (255 aa)

Your Current Organism:

Acanthamoeba castellanii

NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACA1_000210	ACA1_025690	L8H2Y9	L8GIQ2	H/ACA ribonucleoprotein complex subunit 3, putative.	Fibrillarin, putative.	0.695
ACA1_000210	ACA1_052390	L8H2Y9	L8H4W4	H/ACA ribonucleoprotein complex subunit 3, putative.	Nucleolar protein, putative.	0.606
ACA1_000210	ACA1_065750	L8H2Y9	L8GXN8	H/ACA ribonucleoprotein complex subunit 3, putative.	Uncharacterized protein.	0.961
ACA1_000210	ACA1_069240	L8H2Y9	L8HDR9	H/ACA ribonucleoprotein complex subunit 3, putative.	tRNA pseudouridine synthase B, putative.	0.961
ACA1_000210	ACA1_075290	L8H2Y9	L8HFL4	H/ACA ribonucleoprotein complex subunit 3, putative.	rRNA pseudouridine synthase, putative.	0.961
ACA1_000210	ACA1_090040	L8H2Y9	L8GXA1	H/ACA ribonucleoprotein complex subunit 3, putative.	RNA polymerase Rpb3/Rpb11 dimerization domain containing protein.	0.856
ACA1_000210	ACA1_115430	L8H2Y9	L8H5X4	H/ACA ribonucleoprotein complex subunit 3, putative.	DEAD/DEAH box helicase domain containing protein; Belongs to the DEAD box helicase family.	0.653
ACA1_000210	ACA1_125550	L8H2Y9	L8GRD1	H/ACA ribonucleoprotein complex subunit 3, putative.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.537
ACA1_000210	ACA1_137420	L8H2Y9	L8H1X2	H/ACA ribonucleoprotein complex subunit 3, putative.	LYAR-type C2HC zinc finger protein.	0.731
ACA1_000210	ACA1_171240	L8H2Y9	L8HJI5	H/ACA ribonucleoprotein complex subunit 3, putative.	Ribosomal protein L7Ae protein.	0.967
ACA1_000210	ACA1_175720	L8H2Y9	L8HKG2	H/ACA ribonucleoprotein complex subunit 3, putative.	RNA recognition motif domain containing protein.	0.416
ACA1_000210	ACA1_178320	L8H2Y9	L8GU91	H/ACA ribonucleoprotein complex subunit 3, putative.	40S ribosomal protein S9.	0.467
ACA1_000210	ACA1_180800	L8H2Y9	L8GDR3	H/ACA ribonucleoprotein complex subunit 3, putative.	Nucleolar protein Nop56, putative.	0.672
ACA1_000210	ACA1_194930	L8H2Y9	L8H7G0	H/ACA ribonucleoprotein complex subunit 3, putative.	Matrix attachment region binding protein.	0.649
ACA1_000210	ACA1_204570	L8H2Y9	L8GT40	H/ACA ribonucleoprotein complex subunit 3, putative.	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.	0.707
ACA1_000210	ACA1_223050	L8H2Y9	L8GS62	H/ACA ribonucleoprotein complex subunit 3, putative.	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	0.967
ACA1_000210	ACA1_237290	L8H2Y9	L8H3V6	H/ACA ribonucleoprotein complex subunit 3, putative.	Utp21 domain-containing protein.	0.586
ACA1_000210	ACA1_251460	L8H2Y9	L8HAP6	H/ACA ribonucleoprotein complex subunit 3, putative.	U3 small nucleolar ribonucleoprotein component, putative.	0.430
ACA1_000210	ACA1_287860	L8H2Y9	L8HIR6	H/ACA ribonucleoprotein complex subunit 3, putative.	BP28CT domain-containing protein.	0.446
ACA1_000210	ACA1_318520	L8H2Y9	L8GGT6	H/ACA ribonucleoprotein complex subunit 3, putative.	RNA polymerase Rpb7 domain containing protein.	0.418

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