54 items (Acanthamoeba castellanii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ACA1_048550	Tetratricopeptide repeat domain containing protein. (1211 aa)
	ACA1_190240	Rtt106 domain-containing protein. (846 aa)
	ACA1_389090	Transcription initiation factor iid, 31kd subunit protein. (261 aa)
	ACA1_260140	Endonuclease III, putative. (637 aa)
	ACA1_190750	DNAdirected RNA polymerase II subunit RPB7, putative. (153 aa)
	ACA1_257030	WD domain G-beta repeat-containing protein. (725 aa)
	ACA1_050620	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (304 aa)
	ACA1_093730	RNA polymerase subunit. (102 aa)
	ACA1_092940	Uncharacterized protein. (64 aa)
	ACA1_077140	Nuclear cap-binding protein subunit 2. (244 aa)
	ACA1_365330	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (140 aa)
	ACA1_364240	Cyclin, Nterminal domain containing protein; Belongs to the cyclin family. (386 aa)
	ACA1_391550	Ssl1like protein. (360 aa)
	ACA1_051820	Ubiquitin family protein. (103 aa)
	ACA1_066780	Transcription initiation factor tfiid subunit 13, putative. (146 aa)
	ACA1_218440	RNA polymerase Rpb3/Rpb11 dimerization domain containing protein. (122 aa)
	ACA1_218610	Uncharacterized protein. (356 aa)
	ACA1_192060	Initiation factor eif4 gamma, middle, putative. (700 aa)
	ACA1_164980	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (463 aa)
	ACA1_203930	TAF11, putative. (200 aa)
	ACA1_089850	Bromodomain domain containing protein. (1803 aa)
	ACA1_058750	Nucleotide excision repair protein, putative. (696 aa)
	ACA1_203150	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (123 aa)
	ACA1_020820	TATAbox-binding protein. (258 aa)
	ACA1_087480	Transcription factor iia, alpha/beta subunit protein. (255 aa)
	ACA1_209800	Transcription initiation factor tfiid subunit a protein. (266 aa)
	ACA1_066300	Transcription factor SII (TFIIS) domain containing protein. (168 aa)
	ACA1_155710	TAF6_C domain-containing protein. (462 aa)
	ACA1_234280	Uncharacterized protein. (560 aa)
	ACA1_155500	Cofactor of BRCA1 (COBRA1). (603 aa)
	ACA1_266150	PBS lyase HEATlike repeat domain containing protein. (981 aa)
	ACA1_267310	PHDfinger domain containing protein. (468 aa)
	ACA1_234160	Transcription factor tfiib repeat domain containing protein. (303 aa)
	ACA1_111900	Global transcription factor, putative. (1120 aa)
	ACA1_114870	Transcription initiation factor tfiid component taf4 family protein. (778 aa)
	ACA1_053640	Transcription elongation factor SPT5. (1184 aa)
	ACA1_116890	DNA-directed RNA polymerase II family protein. (151 aa)
	ACA1_278190	CDK-activating kinase assembly factor MAT1 protein. (262 aa)
	ACA1_225900	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (465 aa)
	ACA1_024370	Uncharacterized protein. (255 aa)
	ACA1_158460	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1196 aa)
	ACA1_142400	Plus3 domain containing protein. (627 aa)
	ACA1_068880	WD domain, G-beta repeat-containing protein. (978 aa)
	ACA1_144380	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1378 aa)
	ACA1_169330	RNA polymerase Rpb5, Cterminal domain containing protein. (204 aa)
	ACA1_072640	TAFII55_N domain-containing protein. (487 aa)
	ACA1_300860	Transcription factor tfiib repeat domain containing protein. (371 aa)
	ACA1_289980	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (930 aa)
	ACA1_291620	DNAdirected RNA polymerase II subunit rpb4, putative. (135 aa)
	ACA1_287780	IWS1 Cterminus domain containing protein. (661 aa)
	ACA1_171520	DNA repair helicase rad25 subfamily protein. (560 aa)
	ACA1_326090	Uncharacterized protein. (421 aa)
	ACA1_291010	TAF9 RNA polymerase II, TATA box binding protein (TBP)associated factor, putative. (127 aa)
	ACA1_296980	Histone chaperone rttp106 family protein. (281 aa)

Your Current Organism:

Acanthamoeba castellanii

NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACA1_020820	ACA1_024370	L8GWH4	L8H9Y9	TATAbox-binding protein.	Uncharacterized protein.	0.565
ACA1_020820	ACA1_050620	L8GWH4	L8GHP6	TATAbox-binding protein.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.937
ACA1_020820	ACA1_053640	L8GWH4	L8H676	TATAbox-binding protein.	Transcription elongation factor SPT5.	0.565
ACA1_020820	ACA1_058750	L8GWH4	L8GVG5	TATAbox-binding protein.	Nucleotide excision repair protein, putative.	0.970
ACA1_020820	ACA1_066300	L8GWH4	L8GZ47	TATAbox-binding protein.	Transcription factor SII (TFIIS) domain containing protein.	0.940
ACA1_020820	ACA1_066780	L8GWH4	L8GP29	TATAbox-binding protein.	Transcription initiation factor tfiid subunit 13, putative.	0.998
ACA1_020820	ACA1_068880	L8GWH4	L8HCN1	TATAbox-binding protein.	WD domain, G-beta repeat-containing protein.	0.959
ACA1_020820	ACA1_072640	L8GWH4	L8HGU0	TATAbox-binding protein.	TAFII55_N domain-containing protein.	0.998
ACA1_020820	ACA1_087480	L8GWH4	L8GWV4	TATAbox-binding protein.	Transcription factor iia, alpha/beta subunit protein.	0.998
ACA1_020820	ACA1_089850	L8GWH4	L8GUU7	TATAbox-binding protein.	Bromodomain domain containing protein.	0.998
ACA1_020820	ACA1_092940	L8GWH4	L8GIT1	TATAbox-binding protein.	Uncharacterized protein.	0.982
ACA1_020820	ACA1_093730	L8GWH4	L8GIK6	TATAbox-binding protein.	RNA polymerase subunit.	0.981
ACA1_020820	ACA1_114870	L8GWH4	L8H4I0	TATAbox-binding protein.	Transcription initiation factor tfiid component taf4 family protein.	0.998
ACA1_020820	ACA1_116890	L8GWH4	L8H6X7	TATAbox-binding protein.	DNA-directed RNA polymerase II family protein.	0.978
ACA1_020820	ACA1_144380	L8GWH4	L8HFM7	TATAbox-binding protein.	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.	0.452
ACA1_020820	ACA1_155710	L8GWH4	L8GZG8	TATAbox-binding protein.	TAF6_C domain-containing protein.	0.998
ACA1_020820	ACA1_158460	L8GWH4	L8HA21	TATAbox-binding protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.982
ACA1_020820	ACA1_169330	L8GWH4	L8HGI6	TATAbox-binding protein.	RNA polymerase Rpb5, Cterminal domain containing protein.	0.991
ACA1_020820	ACA1_171520	L8GWH4	L8HIS6	TATAbox-binding protein.	DNA repair helicase rad25 subfamily protein.	0.980
ACA1_020820	ACA1_190750	L8GWH4	L8GF23	TATAbox-binding protein.	DNAdirected RNA polymerase II subunit RPB7, putative.	0.983

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