35 items (Acanthamoeba castellanii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ACA1_053240	Phosphoglycerate kinase. (417 aa)
	ACA1_328060	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (346 aa)
	ACA1_200220	Fructose-1,6-bisphosphatase, putative; Belongs to the FBPase class 1 family. (342 aa)
	ACA1_198400	Citrate transport family protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (310 aa)
	ACA1_236650	Calciumbinding mitochondrial carrier protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (733 aa)
	ACA1_155560	Aspartate aminotransferase. (440 aa)
	ACA1_369570	Tetratricopeptide repeat domain containing protein. (359 aa)
	ACA1_350820	Aspartate aminotransferase. (441 aa)
	ACA1_002300	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1209 aa)
	ACA1_167340	2-oxoglutarate/malate carrier protein, putative; Belongs to the mitochondrial carrier (TC 2.A.29) family. (313 aa)
	ACA1_276210	Aspartate aminotransferase. (415 aa)
	ACA1_275720	Enolase, Cterminal TIM barrel domain containing protein. (435 aa)
	ACA1_066870	Glucose-6-phosphate isomerase; Belongs to the GPI family. (561 aa)
	ACA1_276320	Aspartate aminotransferase, mitochondrial, putative. (78 aa)
	ACA1_220710	Malate dehydrogenase. (306 aa)
	ACA1_217750	Phosphoenolpyruvate carboxykinase (GTP), putative. (1218 aa)
	ACA1_191500	Phosphoenolpyruvate carboxykinase (GTP), putative. (614 aa)
	ACA1_092870	Aromatic ringopening dioxygenase, catalytic subunit LigB superfamily protein. (290 aa)
	ACA1_097030	Carrier superfamily protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (594 aa)
	ACA1_095750	Mitochondrial carrier protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (225 aa)
	ACA1_274740	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (69 aa)
	ACA1_274580	Carrier superfamily protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (291 aa)
	ACA1_399830	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (346 aa)
	ACA1_191150	Triosephosphate isomerase. (211 aa)
	ACA1_145170	Carrier superfamily protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (631 aa)
	ACA1_119240	Aspartate aminotransferase. (437 aa)
	ACA1_166070	Malate dehydrogenase. (343 aa)
	ACA1_165810	Amidohydrolase domain containing protein. (883 aa)
	ACA1_069910	Citrin, putative; Belongs to the mitochondrial carrier (TC 2.A.29) family. (311 aa)
	ACA1_152960	Malate dehydrogenase. (416 aa)
	ACA1_073440	Transporter, major facilitator subfamily protein. (519 aa)
	ACA1_360340	Urb2 domain-containing protein. (1921 aa)
	ACA1_255530	Carrier superfamily protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (331 aa)
	ACA1_157810	Amidohydrolase family protein. (381 aa)
	ACA1_284210	Oxoglutarate carrier, putative; Belongs to the mitochondrial carrier (TC 2.A.29) family. (297 aa)

Your Current Organism:

Acanthamoeba castellanii

NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACA1_002300	ACA1_053240	L8GTX8	L8H831	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Phosphoglycerate kinase.	0.511
ACA1_002300	ACA1_066870	L8GTX8	L8GRA3	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.544
ACA1_002300	ACA1_119240	L8GTX8	L8HKA6	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Aspartate aminotransferase.	0.883
ACA1_002300	ACA1_152960	L8GTX8	L8HFT9	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Malate dehydrogenase.	0.969
ACA1_002300	ACA1_155560	L8GTX8	L8GZF4	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Aspartate aminotransferase.	0.883
ACA1_002300	ACA1_166070	L8GTX8	L8HIY2	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Malate dehydrogenase.	0.969
ACA1_002300	ACA1_191150	L8GTX8	L8GE90	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Triosephosphate isomerase.	0.528
ACA1_002300	ACA1_191500	L8GTX8	L8GN92	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Phosphoenolpyruvate carboxykinase (GTP), putative.	0.943
ACA1_002300	ACA1_200220	L8GTX8	L8H3E2	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Fructose-1,6-bisphosphatase, putative; Belongs to the FBPase class 1 family.	0.511
ACA1_002300	ACA1_217750	L8GTX8	L8GQL5	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Phosphoenolpyruvate carboxykinase (GTP), putative.	0.454
ACA1_002300	ACA1_220710	L8GTX8	L8GQP0	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Malate dehydrogenase.	0.969
ACA1_002300	ACA1_275720	L8GTX8	L8GRZ9	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Enolase, Cterminal TIM barrel domain containing protein.	0.454
ACA1_002300	ACA1_276210	L8GTX8	L8GTG7	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Aspartate aminotransferase.	0.883
ACA1_002300	ACA1_276320	L8GTX8	L8GR45	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Aspartate aminotransferase, mitochondrial, putative.	0.441
ACA1_002300	ACA1_350820	L8GTX8	L8GY58	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Aspartate aminotransferase.	0.883
ACA1_002300	ACA1_360340	L8GTX8	L8HBW1	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Urb2 domain-containing protein.	0.712
ACA1_002300	ACA1_369570	L8GTX8	L8GY79	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Tetratricopeptide repeat domain containing protein.	0.454
ACA1_053240	ACA1_002300	L8H831	L8GTX8	Phosphoglycerate kinase.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.511
ACA1_053240	ACA1_066870	L8H831	L8GRA3	Phosphoglycerate kinase.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.975
ACA1_053240	ACA1_152960	L8H831	L8HFT9	Phosphoglycerate kinase.	Malate dehydrogenase.	0.533

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