35 items (Acanthamoeba castellanii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ACA1_096940	Uncharacterized protein. (404 aa)
	ACA1_176040	Zinc knuckle domain containing protein. (263 aa)
	ACA1_073270	THO complex 3 family protein. (255 aa)
	ACA1_075260	Uncharacterized protein. (178 aa)
	ACA1_249770	Uncharacterized protein. (466 aa)
	ACA1_070640	RNA recognition motif domain containing protein. (348 aa)
	ACA1_281200	MOR2-PAG1_mid domain-containing protein. (1990 aa)
	ACA1_182910	RNA recognition motif domain containing protein. (195 aa)
	ACA1_268930	PWI domain containing protein. (457 aa)
	ACA1_232660	Uncharacterized protein. (312 aa)
	ACA1_155210	Protein CLP1 homolog; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation; Belongs to the Clp1 family. Clp1 subfamily. (427 aa)
	ACA1_369140	PremRNA-splicing factor ATP-dependent RNA helicase PRP16, putative. (1242 aa)
	ACA1_057080	RNA recognition motif domain containing protein. (347 aa)
	ACA1_369110	Small nuclear ribonucleoprotein G. (76 aa)
	ACA1_063910	Tho complex subunit 7 protein. (281 aa)
	ACA1_061520	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (90 aa)
	ACA1_204060	Btz domain-containing protein. (347 aa)
	ACA1_042680	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (217 aa)
	ACA1_057390	LSM domain containing protein. (204 aa)
	ACA1_331480	Membraneassociated ring finger (C3HC4) 2, putative. (210 aa)
	ACA1_192060	Initiation factor eif4 gamma, middle, putative. (700 aa)
	ACA1_210210	THO1 protein (Nuclear matrix protein p84), putative. (451 aa)
	ACA1_130970	THO2 protein. (1521 aa)
	ACA1_193250	WD40 repeat family protein. (434 aa)
	ACA1_138760	U2 snRNP auxilliary factor, large subunit, splicing factor subfamily protein. (462 aa)
	ACA1_366760	RNA recognition motif domain containing protein. (239 aa)
	ACA1_327400	Uncharacterized protein. (549 aa)
	ACA1_077140	Nuclear cap-binding protein subunit 2. (244 aa)
	ACA1_038370	Uncharacterized protein. (374 aa)
	ACA1_134990	Small nuclear ribonucleoprotein Sm D3. (136 aa)
	ACA1_190630	RNA recognition motif domain containing protein. (253 aa)
	ACA1_388770	Poly(A) polymerase central domain containing protein. (1230 aa)
	ACA1_261450	TrkA Cterminal domain containing protein. (746 aa)
	ACA1_260090	THO complex 5, putative. (527 aa)
	ACA1_388780	EGFlike domain containing protein. (904 aa)

Your Current Organism:

Acanthamoeba castellanii

NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACA1_038370	ACA1_063910	L8GKX2	L8GXH2	Uncharacterized protein.	Tho complex subunit 7 protein.	0.699
ACA1_038370	ACA1_073270	L8GKX2	L8HG33	Uncharacterized protein.	THO complex 3 family protein.	0.645
ACA1_038370	ACA1_077140	L8GKX2	L8GLA6	Uncharacterized protein.	Nuclear cap-binding protein subunit 2.	0.552
ACA1_038370	ACA1_096940	L8GKX2	L8GLD2	Uncharacterized protein.	Uncharacterized protein.	0.604
ACA1_038370	ACA1_130970	L8GKX2	L8GPL5	Uncharacterized protein.	THO2 protein.	0.604
ACA1_038370	ACA1_182910	L8GKX2	L8H7Y4	Uncharacterized protein.	RNA recognition motif domain containing protein.	0.455
ACA1_038370	ACA1_204060	L8GKX2	L8GW81	Uncharacterized protein.	Btz domain-containing protein.	0.604
ACA1_038370	ACA1_210210	L8GKX2	L8GPN1	Uncharacterized protein.	THO1 protein (Nuclear matrix protein p84), putative.	0.547
ACA1_038370	ACA1_249770	L8GKX2	L8HEE4	Uncharacterized protein.	Uncharacterized protein.	0.547
ACA1_038370	ACA1_260090	L8GKX2	L8GF07	Uncharacterized protein.	THO complex 5, putative.	0.742
ACA1_038370	ACA1_327400	L8GKX2	L8GMG5	Uncharacterized protein.	Uncharacterized protein.	0.547
ACA1_038370	ACA1_331480	L8GKX2	L8GT05	Uncharacterized protein.	Membraneassociated ring finger (C3HC4) 2, putative.	0.662
ACA1_038370	ACA1_369140	L8GKX2	L8GZ15	Uncharacterized protein.	PremRNA-splicing factor ATP-dependent RNA helicase PRP16, putative.	0.405
ACA1_042680	ACA1_061520	L8GVB5	L8GWT6	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.	0.445
ACA1_042680	ACA1_063910	L8GVB5	L8GXH2	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]	Tho complex subunit 7 protein.	0.742
ACA1_042680	ACA1_070640	L8GVB5	L8HE36	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]	RNA recognition motif domain containing protein.	0.708
ACA1_042680	ACA1_073270	L8GVB5	L8HG33	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]	THO complex 3 family protein.	0.741
ACA1_042680	ACA1_075260	L8GVB5	L8HFB9	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]	Uncharacterized protein.	0.733
ACA1_042680	ACA1_077140	L8GVB5	L8GLA6	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]	Nuclear cap-binding protein subunit 2.	0.812
ACA1_042680	ACA1_096940	L8GVB5	L8GLD2	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]	Uncharacterized protein.	0.625

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