31 items (Acanthamoeba castellanii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	ACA1_048550	Tetratricopeptide repeat domain containing protein. (1211 aa)
	ACA1_190240	Rtt106 domain-containing protein. (846 aa)
	ACA1_190750	DNAdirected RNA polymerase II subunit RPB7, putative. (153 aa)
	ACA1_050620	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (304 aa)
	ACA1_093730	RNA polymerase subunit. (102 aa)
	ACA1_092940	Uncharacterized protein. (64 aa)
	ACA1_077140	Nuclear cap-binding protein subunit 2. (244 aa)
	ACA1_365330	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (140 aa)
	ACA1_364240	Cyclin, Nterminal domain containing protein; Belongs to the cyclin family. (386 aa)
	ACA1_391550	Ssl1like protein. (360 aa)
	ACA1_051820	Ubiquitin family protein. (103 aa)
	ACA1_218440	RNA polymerase Rpb3/Rpb11 dimerization domain containing protein. (122 aa)
	ACA1_218610	Uncharacterized protein. (356 aa)
	ACA1_192060	Initiation factor eif4 gamma, middle, putative. (700 aa)
	ACA1_058750	Nucleotide excision repair protein, putative. (696 aa)
	ACA1_066300	Transcription factor SII (TFIIS) domain containing protein. (168 aa)
	ACA1_234280	Uncharacterized protein. (560 aa)
	ACA1_053640	Transcription elongation factor SPT5. (1184 aa)
	ACA1_116890	DNA-directed RNA polymerase II family protein. (151 aa)
	ACA1_278190	CDK-activating kinase assembly factor MAT1 protein. (262 aa)
	ACA1_225900	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (465 aa)
	ACA1_024370	Uncharacterized protein. (255 aa)
	ACA1_158460	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1196 aa)
	ACA1_142400	Plus3 domain containing protein. (627 aa)
	ACA1_144380	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1378 aa)
	ACA1_169330	RNA polymerase Rpb5, Cterminal domain containing protein. (204 aa)
	ACA1_289980	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (930 aa)
	ACA1_291620	DNAdirected RNA polymerase II subunit rpb4, putative. (135 aa)
	ACA1_287780	IWS1 Cterminus domain containing protein. (661 aa)
	ACA1_171520	DNA repair helicase rad25 subfamily protein. (560 aa)
	ACA1_326090	Uncharacterized protein. (421 aa)

Your Current Organism:

Acanthamoeba castellanii

NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACA1_024370	ACA1_048550	L8H9Y9	L8GDY1	Uncharacterized protein.	Tetratricopeptide repeat domain containing protein.	0.905
ACA1_024370	ACA1_050620	L8H9Y9	L8GHP6	Uncharacterized protein.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.662
ACA1_024370	ACA1_066300	L8H9Y9	L8GZ47	Uncharacterized protein.	Transcription factor SII (TFIIS) domain containing protein.	0.862
ACA1_024370	ACA1_077140	L8H9Y9	L8GLA6	Uncharacterized protein.	Nuclear cap-binding protein subunit 2.	0.691
ACA1_024370	ACA1_092940	L8H9Y9	L8GIT1	Uncharacterized protein.	Uncharacterized protein.	0.943
ACA1_024370	ACA1_093730	L8H9Y9	L8GIK6	Uncharacterized protein.	RNA polymerase subunit.	0.949
ACA1_024370	ACA1_116890	L8H9Y9	L8H6X7	Uncharacterized protein.	DNA-directed RNA polymerase II family protein.	0.949
ACA1_024370	ACA1_142400	L8H9Y9	L8HAK6	Uncharacterized protein.	Plus3 domain containing protein.	0.896
ACA1_024370	ACA1_144380	L8H9Y9	L8HFM7	Uncharacterized protein.	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.	0.918
ACA1_024370	ACA1_158460	L8H9Y9	L8HA21	Uncharacterized protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.966
ACA1_024370	ACA1_169330	L8H9Y9	L8HGI6	Uncharacterized protein.	RNA polymerase Rpb5, Cterminal domain containing protein.	0.959
ACA1_024370	ACA1_190240	L8H9Y9	L8GE68	Uncharacterized protein.	Rtt106 domain-containing protein.	0.914
ACA1_024370	ACA1_190750	L8H9Y9	L8GF23	Uncharacterized protein.	DNAdirected RNA polymerase II subunit RPB7, putative.	0.959
ACA1_024370	ACA1_192060	L8H9Y9	L8GQR7	Uncharacterized protein.	Initiation factor eif4 gamma, middle, putative.	0.677
ACA1_024370	ACA1_218440	L8H9Y9	L8GQD6	Uncharacterized protein.	RNA polymerase Rpb3/Rpb11 dimerization domain containing protein.	0.941
ACA1_024370	ACA1_218610	L8H9Y9	L8GQN3	Uncharacterized protein.	Uncharacterized protein.	0.855
ACA1_024370	ACA1_225900	L8H9Y9	L8H8M7	Uncharacterized protein.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.662
ACA1_024370	ACA1_234280	L8H9Y9	L8H154	Uncharacterized protein.	Uncharacterized protein.	0.898
ACA1_024370	ACA1_278190	L8H9Y9	L8H822	Uncharacterized protein.	CDK-activating kinase assembly factor MAT1 protein.	0.667
ACA1_024370	ACA1_287780	L8H9Y9	L8HIQ8	Uncharacterized protein.	IWS1 Cterminus domain containing protein.	0.899

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