STRINGSTRING
ACA1_272660 ACA1_272660 ACA1_108290 ACA1_108290 ACA1_048060 ACA1_048060 ACA1_387900 ACA1_387900 ACA1_351900 ACA1_351900 ACA1_145760 ACA1_145760 ACA1_048490 ACA1_048490 ACA1_260010 ACA1_260010 ACA1_256970 ACA1_256970 ACA1_274410 ACA1_274410 ACA1_362710 ACA1_362710 ACA1_353600 ACA1_353600 ACA1_400240 ACA1_400240 ACA1_275280 ACA1_275280 ACA1_321210 ACA1_321210 ACA1_399820 ACA1_399820 ACA1_140980 ACA1_140980 ACA1_258690 ACA1_258690 ACA1_092650 ACA1_092650 ACA1_309490 ACA1_309490 ACA1_092970 ACA1_092970 ACA1_093450 ACA1_093450 ACA1_101470 ACA1_101470 ACA1_021690 ACA1_021690 ACA1_242050 ACA1_242050 ACA1_239230 ACA1_239230 ACA1_038570 ACA1_038570 ACA1_094250 ACA1_094250 ACA1_020160 ACA1_020160 ACA1_076070 ACA1_076070 ACA1_038380 ACA1_038380 ACA1_366460 ACA1_366460 ACA1_106710 ACA1_106710 ACA1_191700 ACA1_191700 ACA1_381600 ACA1_381600 ACA1_325260 ACA1_325260 ACA1_271280 ACA1_271280 ACA1_275660 ACA1_275660 ACA1_379260 ACA1_379260 ACA1_223300 ACA1_223300 ACA1_202120 ACA1_202120 ACA1_336910 ACA1_336910 ACA1_041910 ACA1_041910 ACA1_043350 ACA1_043350 ACA1_347020 ACA1_347020 ACA1_203500 ACA1_203500 ACA1_204480 ACA1_204480 ACA1_058730 ACA1_058730 ACA1_296310 ACA1_296310 ACA1_084890 ACA1_084890 ACA1_295300 ACA1_295300 ACA1_289830 ACA1_289830 ACA1_333210 ACA1_333210 ACA1_110040 ACA1_110040 ACA1_175980 ACA1_175980 ACA1_175600 ACA1_175600 ACA1_174530 ACA1_174530 ACA1_287700 ACA1_287700 ACA1_143280 ACA1_143280 ACA1_376740 ACA1_376740 ACA1_071350 ACA1_071350 ACA1_342400 ACA1_342400 ACA1_143620 ACA1_143620 ACA1_070410 ACA1_070410 ACA1_195390 ACA1_195390 ACA1_143940 ACA1_143940 ACA1_068070 ACA1_068070 ACA1_360590 ACA1_360590 ACA1_080680 ACA1_080680 ACA1_036330 ACA1_036330 ACA1_068410 ACA1_068410 ACA1_070570 ACA1_070570 ACA1_251580 ACA1_251580 ACA1_158810 ACA1_158810 ACA1_254400 ACA1_254400 ACA1_396150 ACA1_396150 ACA1_397180 ACA1_397180 ACA1_396730 ACA1_396730 ACA1_251570 ACA1_251570 ACA1_252880 ACA1_252880 ACA1_384010 ACA1_384010 ACA1_321940 ACA1_321940 ACA1_285550 ACA1_285550 ACA1_184340 ACA1_184340 ACA1_325540 ACA1_325540 ACA1_182040 ACA1_182040 ACA1_157360 ACA1_157360 ACA1_053340 ACA1_053340 ACA1_277990 ACA1_277990 ACA1_283220 ACA1_283220 ACA1_284100 ACA1_284100 ACA1_182980 ACA1_182980 ACA1_195000 ACA1_195000 ACA1_113510 ACA1_113510 ACA1_054170 ACA1_054170 ACA1_054070 ACA1_054070 ACA1_279410 ACA1_279410 ACA1_111990 ACA1_111990 ACA1_114420 ACA1_114420 ACA1_338800 ACA1_338800 ACA1_198820 ACA1_198820 ACA1_112110 ACA1_112110 ACA1_111550 ACA1_111550 ACA1_054030 ACA1_054030 ACA1_186860 ACA1_186860 ACA1_268420 ACA1_268420 ACA1_115370 ACA1_115370 ACA1_265300 ACA1_265300 ACA1_264390 ACA1_264390 ACA1_006680 ACA1_006680 ACA1_201450 ACA1_201450 ACA1_393920 ACA1_393920 ACA1_268110 ACA1_268110 ACA1_267290 ACA1_267290 ACA1_154720 ACA1_154720 ACA1_267900 ACA1_267900 ACA1_267280 ACA1_267280 ACA1_265330 ACA1_265330 ACA1_232520 ACA1_232520 ACA1_209230 ACA1_209230 ACA1_208440 ACA1_208440 ACA1_136790 ACA1_136790 ACA1_369860 ACA1_369860 ACA1_298850 ACA1_298850 ACA1_369250 ACA1_369250 ACA1_064530 ACA1_064530 ACA1_151110 ACA1_151110 ACA1_155820 ACA1_155820 ACA1_062080 ACA1_062080 ACA1_045090 ACA1_045090 ACA1_208140 ACA1_208140 ACA1_369670 ACA1_369670 ACA1_207470 ACA1_207470 ACA1_248870 ACA1_248870 ACA1_368200 ACA1_368200 ACA1_065040 ACA1_065040 ACA1_058290 ACA1_058290 ACA1_063060 ACA1_063060 ACA1_063340 ACA1_063340 ACA1_066100 ACA1_066100 ACA1_061970 ACA1_061970 ACA1_061100 ACA1_061100 ACA1_028670 ACA1_028670
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACA1_272660Alpha-l-fucosidase family protein; Belongs to the glycosyl hydrolase 29 family. (446 aa)
ACA1_108290Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. (215 aa)
ACA1_048060Vps51/Vps67 protein. (1093 aa)
ACA1_387900ADPribosylation factor 1, putative; Belongs to the small GTPase superfamily. Arf family. (181 aa)
ACA1_351900Uncharacterized protein. (238 aa)
ACA1_145760Legumelike lectin family protein. (619 aa)
ACA1_048490Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1217 aa)
ACA1_260010SNARE domain containing protein. (137 aa)
ACA1_256970Coated vesicle membrane protein isoform 3, putative. (216 aa)
ACA1_274410Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (149 aa)
ACA1_362710ADPribosylation factor, putative; Belongs to the small GTPase superfamily. Arf family. (173 aa)
ACA1_353600Zetacop, subunit of COP-I complex, putative. (189 aa)
ACA1_400240Calponin domain containing protein. (555 aa)
ACA1_275280Uncharacterized protein. (199 aa)
ACA1_321210Alphaactinin, putative. (631 aa)
ACA1_399820VSNARE family protein. (219 aa)
ACA1_140980Calponin domain containing protein. (304 aa)
ACA1_258690Vesicle trafficking protein, putative; Belongs to the synaptobrevin family. (212 aa)
ACA1_092650Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (460 aa)
ACA1_309490Clathrin adaptor complex small chain subfamily protein. (186 aa)
ACA1_092970ADPribosylation factor 1, putative; Belongs to the small GTPase superfamily. Arf family. (184 aa)
ACA1_093450Tubulin/FtsZ family, GTPase domain containing protein; Belongs to the tubulin family. (616 aa)
ACA1_101470Dynactin 4 isoform 2, putative. (204 aa)
ACA1_021690Vesicle docking family protein. (531 aa)
ACA1_242050Zetacop, subunit of COP-I complex, putative. (210 aa)
ACA1_239230Small copii coat gtpase sar1, putative; Belongs to the small GTPase superfamily. SAR1 family. (195 aa)
ACA1_038570AlphaL-fucosidase; Belongs to the glycosyl hydrolase 29 family. (472 aa)
ACA1_094250ADPribosylation factor subfamily protein. (1048 aa)
ACA1_020160Sec16_C domain-containing protein. (853 aa)
ACA1_076070Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (155 aa)
ACA1_038380Dynein light chain. (89 aa)
ACA1_366460Dynactin subunit 6, putative. (188 aa)
ACA1_106710Tetratricopeptide repeat domain containing protein. (357 aa)
ACA1_191700Ras subfamily protein. (478 aa)
ACA1_381600Golgi family protein, putative. (827 aa)
ACA1_325260Peptidylprolyl isomerase. (1517 aa)
ACA1_271280Uncharacterized protein. (335 aa)
ACA1_275660alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (1067 aa)
ACA1_379260Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (1000 aa)
ACA1_223300Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (917 aa)
ACA1_202120Tubulin/FtsZ family, GTPase domain containing protein; Belongs to the tubulin family. (356 aa)
ACA1_336910Actin subfamily protein; Belongs to the actin family. (504 aa)
ACA1_041910GNT-I family protein. (566 aa)
ACA1_043350F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (301 aa)
ACA1_347020Sec23/Sec24 trunk domain containing protein. (661 aa)
ACA1_203500Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (534 aa)
ACA1_204480Tubulin/FtsZ family, GTPase domain containing protein; Belongs to the tubulin family. (363 aa)
ACA1_058730Tetratricopeptide repeat domain containing protein. (331 aa)
ACA1_296310Cysteine proteinase, putative; Belongs to the peptidase C1 family. (330 aa)
ACA1_084890ADPribosylation factor, putative; Belongs to the small GTPase superfamily. Arf family. (179 aa)
ACA1_295300Calponin domain containing protein. (2349 aa)
ACA1_289830WD domain, G-beta repeat-containing protein. (372 aa)
ACA1_333210F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (277 aa)
ACA1_110040Galactosyltransferase. (290 aa)
ACA1_175980Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. BET3 subfamily. (198 aa)
ACA1_175600Uncharacterized protein. (441 aa)
ACA1_174530Syntaxin protein, putative; Belongs to the syntaxin family. (304 aa)
ACA1_287700Lethal (1), putative; Belongs to the synaptobrevin family. (201 aa)
ACA1_143280Protein transport protein bet1, putative. (121 aa)
ACA1_376740Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (461 aa)
ACA1_071350GTPbinding ADP-ribosylation factor Arf1, putative; Belongs to the small GTPase superfamily. Arf family. (180 aa)
ACA1_342400Tubulin/FtsZ family, GTPase domain containing protein; Belongs to the tubulin family. (467 aa)
ACA1_143620Sec23/Sec24 trunk domain containing protein. (1016 aa)
ACA1_070410L-type lectin-like domain-containing protein. (383 aa)
ACA1_195390Golgi family protein, putative. (404 aa)
ACA1_143940Type A von Willebrand factor (VWFA) domain containing protein. (802 aa)
ACA1_068070Small GTPbinding ADP-ribosylation factor; Belongs to the small GTPase superfamily. Arf family. (227 aa)
ACA1_360590Uncharacterized protein; Belongs to the synaptobrevin family. (210 aa)
ACA1_080680Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (481 aa)
ACA1_036330Centractin, putative; Belongs to the actin family. (381 aa)
ACA1_068410ADPribosylation factor subfamily protein. (469 aa)
ACA1_070570Sar1family small GTPase; Belongs to the small GTPase superfamily. SAR1 family. (190 aa)
ACA1_251580CDC48_2 domain-containing protein. (235 aa)
ACA1_158810Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family. (303 aa)
ACA1_254400Golgi family protein, putative. (670 aa)
ACA1_396150Dynein heavy chain protein. (4479 aa)
ACA1_397180Uncharacterized protein. (699 aa)
ACA1_396730Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function. (661 aa)
ACA1_251570N-ethylmaleimide-sensitive factor isoform 4, putative; Belongs to the AAA ATPase family. (602 aa)
ACA1_252880Uncharacterized protein. (654 aa)
ACA1_384010Arf GTPase activating protein. (434 aa)
ACA1_321940Uncharacterized protein. (137 aa)
ACA1_285550Protein transport protein sec16; Belongs to the SEC16 family. (1515 aa)
ACA1_184340Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (421 aa)
ACA1_325540Tubulin/FtsZ family, GTPase domain containing protein; Belongs to the tubulin family. (600 aa)
ACA1_182040Uncharacterized protein. (1019 aa)
ACA1_157360Calponin domain containing protein. (337 aa)
ACA1_053340Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (464 aa)
ACA1_277990Calponin domain containing protein. (1565 aa)
ACA1_283220Calponin domain containing protein. (577 aa)
ACA1_284100F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (56 aa)
ACA1_182980SEC13, putative; Belongs to the WD repeat SEC13 family. (310 aa)
ACA1_195000CAPGly domain containing protein. (1481 aa)
ACA1_113510Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (990 aa)
ACA1_054170MIP2A, putative. (145 aa)
ACA1_054070Copii-coated vesicle membrane protein P24, putative. (204 aa)
ACA1_279410Uncharacterized protein. (70 aa)
ACA1_111990Uncharacterized protein. (382 aa)
ACA1_114420F-box domain-containing protein. (454 aa)
ACA1_338800Tubulin/FtsZ family, GTPase domain containing protein. (421 aa)
ACA1_198820Sec34 family protein. (711 aa)
ACA1_112110Glycosyl transferase. (741 aa)
ACA1_111550alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (504 aa)
ACA1_054030PH domain containing protein. (390 aa)
ACA1_186860Golgi family protein, putative. (179 aa)
ACA1_268420Uncharacterized protein. (577 aa)
ACA1_115370Uncharacterized protein. (102 aa)
ACA1_265300COG4 transport protein. (741 aa)
ACA1_264390Transmembrane emp24 protein transport domain containing 9 isoform 3, putative. (236 aa)
ACA1_006680Arginine deiminase. (155 aa)
ACA1_201450ADPribosylation factor, putative; Belongs to the small GTPase superfamily. Arf family. (181 aa)
ACA1_393920Tubulin/FtsZ family, GTPase domain containing protein. (461 aa)
ACA1_268110Brefeldin A resistance guanine nucleotide exchange factor 1 family protein. (106 aa)
ACA1_267290Uncharacterized protein. (522 aa)
ACA1_154720SNARE domain containing protein. (304 aa)
ACA1_267900Brefeldin A resistance factor, putative. (584 aa)
ACA1_267280Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (876 aa)
ACA1_265330F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (280 aa)
ACA1_232520SIT4 phosphataseassociated protein. (739 aa)
ACA1_209230SNARE domain containing protein. (132 aa)
ACA1_208440QaSNARE, SYP3/Sed5p/Syntaxin 5-type, putative; Belongs to the syntaxin family. (320 aa)
ACA1_136790Tubulin/FtsZ family, GTPase domain containing protein; Belongs to the tubulin family. (601 aa)
ACA1_369860GTPbinding protein SARA, putative. (146 aa)
ACA1_298850Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (730 aa)
ACA1_369250Dynactin 50 kDa subunit. (411 aa)
ACA1_064530TBC domain containing protein. (370 aa)
ACA1_151110Sec23/Sec24 trunk domain containing protein. (1016 aa)
ACA1_155820Tubulin/FtsZ family, GTPase domain containing protein; Belongs to the tubulin family. (358 aa)
ACA1_062080DUF2263 domain-containing protein. (408 aa)
ACA1_045090ADPribosylation factor subfamily protein; Belongs to the small GTPase superfamily. Arf family. (300 aa)
ACA1_208140ER lumen proteinretaining receptor-like protein. (213 aa)
ACA1_369670Foie-gras_1 domain-containing protein. (1255 aa)
ACA1_207470Sec1 family domain containing protein; Belongs to the STXBP/unc-18/SEC1 family. (473 aa)
ACA1_248870Coated vesicle membrane protein. (211 aa)
ACA1_368200Uncharacterized protein. (671 aa)
ACA1_065040SIT4 phosphatase-associated protein. (612 aa)
ACA1_058290Glycosyl transferase. (494 aa)
ACA1_063060Ras family GTP-binding protein YPT1. (209 aa)
ACA1_063340Dynein intermediate chain, cytosolic, putative. (644 aa)
ACA1_066100Arf GTPase activating protein. (576 aa)
ACA1_061970Uncharacterized protein. (569 aa)
ACA1_061100SEC13like protein; Belongs to the WD repeat SEC13 family. (289 aa)
ACA1_028670Serine/threonine-protein phosphatase. (304 aa)
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
Server load: low (20%) [HD]