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ACA1_387850 ACA1_387850 ACA1_126980 ACA1_126980 ACA1_191150 ACA1_191150 ACA1_048410 ACA1_048410 ACA1_009930 ACA1_009930 ACA1_127420 ACA1_127420 ACA1_257000 ACA1_257000 ACA1_362550 ACA1_362550 ACA1_095900 ACA1_095900 ACA1_093760 ACA1_093760 ACA1_238250 ACA1_238250 ACA1_240390 ACA1_240390 ACA1_076990 ACA1_076990 ACA1_271340 ACA1_271340 ACA1_130590 ACA1_130590 ACA1_022330 ACA1_022330 ACA1_191560 ACA1_191560 ACA1_366430 ACA1_366430 ACA1_220660 ACA1_220660 ACA1_220710 ACA1_220710 ACA1_066870 ACA1_066870 ACA1_377390 ACA1_377390 ACA1_275720 ACA1_275720 ACA1_163860 ACA1_163860 ACA1_177380 ACA1_177380 ACA1_320830 ACA1_320830 ACA1_188050 ACA1_188050 ACA1_276210 ACA1_276210 ACA1_146430 ACA1_146430 ACA1_031660 ACA1_031660 ACA1_002300 ACA1_002300 ACA1_060510 ACA1_060510 ACA1_383710 ACA1_383710 ACA1_059840 ACA1_059840 ACA1_065210 ACA1_065210 ACA1_368050 ACA1_368050 ACA1_350820 ACA1_350820 ACA1_154220 ACA1_154220 ACA1_155560 ACA1_155560 ACA1_208260 ACA1_208260 ACA1_037190 ACA1_037190 ACA1_267230 ACA1_267230 ACA1_264380 ACA1_264380 ACA1_201370 ACA1_201370 ACA1_199830 ACA1_199830 ACA1_200220 ACA1_200220 ACA1_201580 ACA1_201580 ACA1_263160 ACA1_263160 ACA1_115670 ACA1_115670 ACA1_268920 ACA1_268920 ACA1_307500 ACA1_307500 ACA1_053890 ACA1_053890 ACA1_206000 ACA1_206000 ACA1_284230 ACA1_284230 ACA1_053240 ACA1_053240 ACA1_231010 ACA1_231010 ACA1_280600 ACA1_280600 ACA1_183070 ACA1_183070 ACA1_230800 ACA1_230800 ACA1_183620 ACA1_183620 ACA1_384840 ACA1_384840 ACA1_149940 ACA1_149940 ACA1_158530 ACA1_158530 ACA1_036340 ACA1_036340 ACA1_149380 ACA1_149380 ACA1_359750 ACA1_359750 ACA1_142390 ACA1_142390 ACA1_360150 ACA1_360150 ACA1_398190 ACA1_398190 ACA1_142370 ACA1_142370 ACA1_074410 ACA1_074410 ACA1_396220 ACA1_396220 ACA1_068670 ACA1_068670 ACA1_376730 ACA1_376730 ACA1_152960 ACA1_152960 ACA1_375990 ACA1_375990 ACA1_376500 ACA1_376500 ACA1_376140 ACA1_376140 ACA1_173270 ACA1_173270 ACA1_165250 ACA1_165250 ACA1_302400 ACA1_302400 ACA1_174630 ACA1_174630 ACA1_175190 ACA1_175190 ACA1_295600 ACA1_295600 ACA1_166070 ACA1_166070 ACA1_287370 ACA1_287370 ACA1_119240 ACA1_119240 ACA1_287820 ACA1_287820 ACA1_291490 ACA1_291490 ACA1_295880 ACA1_295880 ACA1_296490 ACA1_296490
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACA1_387850AcylCoA oxidase domain containing protein. (733 aa)
ACA1_126980Aconitate hydratase, cytoplasmic, putative. (393 aa)
ACA1_191150Triosephosphate isomerase. (211 aa)
ACA1_048410Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (650 aa)
ACA1_009930AcylCoA dehydrogenase, putative. (524 aa)
ACA1_127420Aconitate hydratase. (501 aa)
ACA1_2570003-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (320 aa)
ACA1_362550Methylmalonatesemialdehyde dehydrogenase (Acylating), putative. (527 aa)
ACA1_095900Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (366 aa)
ACA1_093760ADPdependent glucokinase. (493 aa)
ACA1_238250Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (602 aa)
ACA1_240390AcylCoA dehydrogenase domain containing protein. (434 aa)
ACA1_076990Aminotransferase. (392 aa)
ACA1_271340Phosphoribosylpyrophosphate synthetase. (307 aa)
ACA1_130590Fumarate hydratase, class II, putative. (499 aa)
ACA1_022330Carbamoylphosphate synthase L chain, ATP-binding, putative. (718 aa)
ACA1_1915606-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (480 aa)
ACA1_366430Fumarate hydratase. (585 aa)
ACA1_220660Phosphoserine transaminase. (394 aa)
ACA1_220710Malate dehydrogenase. (306 aa)
ACA1_066870Glucose-6-phosphate isomerase; Belongs to the GPI family. (561 aa)
ACA1_377390Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (671 aa)
ACA1_275720Enolase, Cterminal TIM barrel domain containing protein. (435 aa)
ACA1_163860Formate-tetrahydrofolate ligase. (631 aa)
ACA1_177380Glucokinase. (352 aa)
ACA1_320830Lipoyl-binding domain-containing protein. (371 aa)
ACA1_188050Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (404 aa)
ACA1_276210Aspartate aminotransferase. (415 aa)
ACA1_146430Catalase. (537 aa)
ACA1_031660Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (487 aa)
ACA1_002300Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1209 aa)
ACA1_060510Mut protein. (709 aa)
ACA1_383710Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (532 aa)
ACA1_059840Phosphoenolpyruvate carboxylase. (916 aa)
ACA1_0652103-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (387 aa)
ACA1_368050MethylmalonylCoA epimerase. (160 aa)
ACA1_350820Aspartate aminotransferase. (441 aa)
ACA1_154220Pyridoxalphosphate dependent superfamily protein. (366 aa)
ACA1_155560Aspartate aminotransferase. (440 aa)
ACA1_208260Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (742 aa)
ACA1_037190Aminotransferase, class V, putative. (421 aa)
ACA1_267230Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (587 aa)
ACA1_264380S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (282 aa)
ACA1_201370Allantoicase repeat domain containing protein. (1076 aa)
ACA1_199830Glycine cleavage system Pprotein. (966 aa)
ACA1_200220Fructose-1,6-bisphosphatase, putative; Belongs to the FBPase class 1 family. (342 aa)
ACA1_2015806-phosphofructokinase family protein. (362 aa)
ACA1_263160Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (321 aa)
ACA1_115670Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (801 aa)
ACA1_268920Oxoglutarate dehydrogenase (Succinyltransferring), E1 component, putative. (1034 aa)
ACA1_307500Alanine aminotransferase, mitochondrial, putative. (514 aa)
ACA1_053890Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (788 aa)
ACA1_206000Succinate dehydrogenase, cytochrome b556 subunit protein. (172 aa)
ACA1_284230Pyruvate kinase; Belongs to the pyruvate kinase family. (522 aa)
ACA1_053240Phosphoglycerate kinase. (417 aa)
ACA1_231010Phosphoenolpyruvate carboxykinase. (396 aa)
ACA1_280600Phosphoribosylpyrophosphate synthetase. (309 aa)
ACA1_183070Cysteine synthase 2, putative. (231 aa)
ACA1_230800Phosphoenolpyruvate carboxykinase. (359 aa)
ACA1_183620Citrate synthase; Belongs to the citrate synthase family. (496 aa)
ACA1_3848403hydroxyacyl-CoA dehydrogenase. (326 aa)
ACA1_149940Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (414 aa)
ACA1_158530Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (499 aa)
ACA1_036340Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (490 aa)
ACA1_149380Ribose 5phosphate isomerase A, putative. (258 aa)
ACA1_359750Succinyl coenzyme A synthetase alpha subunit; Belongs to the succinate/malate CoA ligase alpha subunit family. (278 aa)
ACA1_142390Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (503 aa)
ACA1_360150Malate synthase; Belongs to the malate synthase family. (550 aa)
ACA1_3981906-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (500 aa)
ACA1_142370Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (458 aa)
ACA1_074410Cysteine synthase. (382 aa)
ACA1_396220Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (690 aa)
ACA1_068670Dihydrolipoyl dehydrogenase. (507 aa)
ACA1_376730Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (469 aa)
ACA1_152960Malate dehydrogenase. (416 aa)
ACA1_375990AcetylCoA acetyltransferase, mitochondrial, putative; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
ACA1_376500Isocitrate dehydrogenase subunit 1, mitochondrial, putative. (366 aa)
ACA1_376140AcetylCoA acetyltransferase, mitochondrial, putative; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
ACA1_173270Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (171 aa)
ACA1_165250Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (294 aa)
ACA1_302400AcylCoA dehydrogenase domain containing protein. (372 aa)
ACA1_174630Alanine aminotransferase, mitochondrial, putative. (454 aa)
ACA1_1751906phosphofructokinase. (888 aa)
ACA1_2956006-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (199 aa)
ACA1_166070Malate dehydrogenase. (343 aa)
ACA1_287370Acetate-CoA ligase. (624 aa)
ACA1_119240Aspartate aminotransferase. (437 aa)
ACA1_287820Transketolase. (705 aa)
ACA1_291490Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (225 aa)
ACA1_295880Malic enzyme. (615 aa)
ACA1_296490Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (462 aa)
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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