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ACA1_145760 ACA1_145760 ACA1_191030 ACA1_191030 ACA1_189420 ACA1_189420 ACA1_362540 ACA1_362540 ACA1_260950 ACA1_260950 ACA1_387860 ACA1_387860 ACA1_400570 ACA1_400570 ACA1_374120 ACA1_374120 ACA1_374380 ACA1_374380 ACA1_374090 ACA1_374090 ACA1_374320 ACA1_374320 ACA1_096310 ACA1_096310 ACA1_239260 ACA1_239260 ACA1_330350 ACA1_330350 ACA1_098260 ACA1_098260 ACA1_239230 ACA1_239230 ACA1_097090 ACA1_097090 ACA1_020160 ACA1_020160 ACA1_313740 ACA1_313740 ACA1_305150 ACA1_305150 ACA1_217720 ACA1_217720 ACA1_275940 ACA1_275940 ACA1_275660 ACA1_275660 ACA1_164110 ACA1_164110 ACA1_164160 ACA1_164160 ACA1_377980 ACA1_377980 ACA1_187890 ACA1_187890 ACA1_087560 ACA1_087560 ACA1_179200 ACA1_179200 ACA1_089230 ACA1_089230 ACA1_177550 ACA1_177550 ACA1_058710 ACA1_058710 ACA1_061920 ACA1_061920 ACA1_058840 ACA1_058840 ACA1_063460 ACA1_063460 ACA1_382550 ACA1_382550 ACA1_062200 ACA1_062200 ACA1_138510 ACA1_138510 ACA1_044740 ACA1_044740 ACA1_061090 ACA1_061090 ACA1_248630 ACA1_248630 ACA1_151110 ACA1_151110 ACA1_298850 ACA1_298850 ACA1_369860 ACA1_369860 ACA1_248860 ACA1_248860 ACA1_040830 ACA1_040830 ACA1_372220 ACA1_372220 ACA1_138500 ACA1_138500 ACA1_163130 ACA1_163130 ACA1_368020 ACA1_368020 ACA1_369080 ACA1_369080 ACA1_264710 ACA1_264710 ACA1_266970 ACA1_266970 ACA1_267190 ACA1_267190 ACA1_040460 ACA1_040460 ACA1_236090 ACA1_236090 ACA1_265460 ACA1_265460 ACA1_114920 ACA1_114920 ACA1_201510 ACA1_201510 ACA1_111550 ACA1_111550 ACA1_054780 ACA1_054780 ACA1_205660 ACA1_205660 ACA1_205910 ACA1_205910 ACA1_111060 ACA1_111060 ACA1_000840 ACA1_000840 ACA1_182980 ACA1_182980 ACA1_385430 ACA1_385430 ACA1_046850 ACA1_046850 ACA1_229260 ACA1_229260 ACA1_142350 ACA1_142350 ACA1_253180 ACA1_253180 ACA1_149400 ACA1_149400 ACA1_322570 ACA1_322570 ACA1_070570 ACA1_070570 ACA1_396940 ACA1_396940 ACA1_142590 ACA1_142590 ACA1_069020 ACA1_069020 ACA1_074740 ACA1_074740 ACA1_070410 ACA1_070410 ACA1_169070 ACA1_169070 ACA1_174130 ACA1_174130 ACA1_169060 ACA1_169060 ACA1_175260 ACA1_175260 ACA1_153660 ACA1_153660 ACA1_290110 ACA1_290110 ACA1_289830 ACA1_289830 ACA1_290190 ACA1_290190
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACA1_145760Legumelike lectin family protein. (619 aa)
ACA1_191030CUE domain containing protein. (433 aa)
ACA1_189420Protein disulfideisomerase domain containing protein. (427 aa)
ACA1_362540Zinc finger, C3HC4 type (RING finger) domain containing protein. (474 aa)
ACA1_260950Ribonuclease 25A protein. (1111 aa)
ACA1_387860High molecular weight heat shock protein; Belongs to the heat shock protein 70 family. (666 aa)
ACA1_400570Ubiquitin domain containing protein. (548 aa)
ACA1_374120Protein disulfide-isomerase. (607 aa)
ACA1_374380Heat shock protein ssa1, putative; Belongs to the heat shock protein 70 family. (622 aa)
ACA1_374090Protein disulfide-isomerase. (482 aa)
ACA1_374320UBA/TSN domain containing protein. (305 aa)
ACA1_096310DnaK family protein; Belongs to the heat shock protein 70 family. (621 aa)
ACA1_239260Eukaryotic translation initiation factor 2 alpha subunit, putative. (216 aa)
ACA1_330350SEP domain containing protein. (374 aa)
ACA1_098260Mannosyl oligosaccharide glucosidase. (603 aa)
ACA1_239230Small copii coat gtpase sar1, putative; Belongs to the small GTPase superfamily. SAR1 family. (195 aa)
ACA1_097090Transloconassociated protein, putative. (262 aa)
ACA1_020160Sec16_C domain-containing protein. (853 aa)
ACA1_313740Fbox domain containing protein. (619 aa)
ACA1_305150Protein disulfide isomerase associated 4, putative; Belongs to the protein disulfide isomerase family. (476 aa)
ACA1_217720Ubiquitinconjugating enzyme subfamily protein. (263 aa)
ACA1_275940B-cell receptor-associated protein 31 family protein. (223 aa)
ACA1_275660alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (1067 aa)
ACA1_164110SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (125 aa)
ACA1_164160Peptidase, M50 domain containing protein. (513 aa)
ACA1_377980NPL4 family protein. (392 aa)
ACA1_187890Ubiquitinconjugating enzyme E2, putative; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
ACA1_087560Transloconassociated protein subunit beta, putative. (191 aa)
ACA1_179200Bap31 domain-containing protein. (134 aa)
ACA1_089230Protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic, putative. (68 aa)
ACA1_177550PUL domain containing protein. (787 aa)
ACA1_058710Sphase kinase-associated protein, putative; Belongs to the SKP1 family. (159 aa)
ACA1_061920Rad23, putative. (393 aa)
ACA1_058840Heat shock protein gp96, putative. (798 aa)
ACA1_063460ATPase, AAA domain containing protein. (510 aa)
ACA1_382550Sulfur metabolism negative regulator SconC, putative; Belongs to the SKP1 family. (146 aa)
ACA1_062200Ubiquitin fusion degradation protein 1, putative. (284 aa)
ACA1_138510Legume lectins beta domain containing protein. (699 aa)
ACA1_044740Uncharacterized protein. (290 aa)
ACA1_061090alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (838 aa)
ACA1_248630Thioredoxin domain containing protein. (406 aa)
ACA1_151110Sec23/Sec24 trunk domain containing protein. (1016 aa)
ACA1_298850Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (730 aa)
ACA1_369860GTPbinding protein SARA, putative. (146 aa)
ACA1_248860Transloconassociated protein subunit gamma, putative. (172 aa)
ACA1_040830Ubiquitinconjugating enzyme protein E2, putative; Belongs to the ubiquitin-conjugating enzyme family. (167 aa)
ACA1_372220Deubiquinating enzyme, putative. (246 aa)
ACA1_138500Ubiquitinconjugating enzyme subfamily protein. (239 aa)
ACA1_163130Eukaryotic initiation factor, putative. (298 aa)
ACA1_368020RINGbox protein 1, putative. (123 aa)
ACA1_369080UDPglucose:Glycoprotein Glucosyltransferase containing protein. (1584 aa)
ACA1_264710Membranebound transcription factor protease, site 1 isoform 1, putative. (1042 aa)
ACA1_266970DnaK family superfamily protein. (535 aa)
ACA1_267190Thioredoxin domain containing protein. (461 aa)
ACA1_040460Protein disulfideisomerase, putative; Belongs to the protein disulfide isomerase family. (358 aa)
ACA1_236090PUL domain containing protein. (421 aa)
ACA1_265460Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (716 aa)
ACA1_114920Ubiquitin interaction motif domain containing protein. (269 aa)
ACA1_201510Ubiquitin fusion degradation protein, putative. (556 aa)
ACA1_111550alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (504 aa)
ACA1_054780Zinc finger domain containing protein. (208 aa)
ACA1_205660Heat shock protein 82, putative. (402 aa)
ACA1_205910Heat shock protein 90 alpha, putative. (716 aa)
ACA1_111060Xtp3transactivated protein, putative. (249 aa)
ACA1_000840PRKCSH-like domain-containing protein. (356 aa)
ACA1_182980SEC13, putative; Belongs to the WD repeat SEC13 family. (310 aa)
ACA1_385430S-phase kinase-associated protein 1A isoform b, putative; Belongs to the SKP1 family. (175 aa)
ACA1_046850OTU family cysteine protease. (204 aa)
ACA1_229260alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (793 aa)
ACA1_142350Calreticulin. (408 aa)
ACA1_253180ARM repeat fold domain containing protein. (311 aa)
ACA1_149400Transport protein Sec61 alpha subunit, putative. (462 aa)
ACA1_322570Hsp40, putative. (412 aa)
ACA1_070570Sar1family small GTPase; Belongs to the small GTPase superfamily. SAR1 family. (190 aa)
ACA1_396940OST3 / OST6 family protein. (298 aa)
ACA1_142590Sel1 repeat-containing protein. (630 aa)
ACA1_069020Thioredoxin domain containing protein. (238 aa)
ACA1_074740Thioredoxin domain containing protein. (347 aa)
ACA1_070410L-type lectin-like domain-containing protein. (383 aa)
ACA1_169070Integral membrane protein 1 isoform 5, putative. (718 aa)
ACA1_174130Hsp40, putative. (426 aa)
ACA1_169060Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (229 aa)
ACA1_175260DnaK family superfamily protein. (935 aa)
ACA1_153660Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (110 aa)
ACA1_290110Eukaryotic translation initiation factor 2alpha kinase 1, putative. (1699 aa)
ACA1_289830WD domain, G-beta repeat-containing protein. (372 aa)
ACA1_290190SCF ubiquitin ligase complex protein SKP1a, putative; Belongs to the SKP1 family. (162 aa)
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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