STRINGSTRING
ACA1_145230 ACA1_145230 ACA1_387900 ACA1_387900 ACA1_048130 ACA1_048130 ACA1_121520 ACA1_121520 ACA1_261570 ACA1_261570 ACA1_362710 ACA1_362710 ACA1_260070 ACA1_260070 ACA1_387860 ACA1_387860 ACA1_139840 ACA1_139840 ACA1_374380 ACA1_374380 ACA1_101500 ACA1_101500 ACA1_256400 ACA1_256400 ACA1_373890 ACA1_373890 ACA1_399850 ACA1_399850 ACA1_092970 ACA1_092970 ACA1_093490 ACA1_093490 ACA1_097740 ACA1_097740 ACA1_091160 ACA1_091160 ACA1_096470 ACA1_096470 ACA1_246860 ACA1_246860 ACA1_120810 ACA1_120810 ACA1_359270 ACA1_359270 ACA1_364700 ACA1_364700 ACA1_366160 ACA1_366160 ACA1_366670 ACA1_366670 ACA1_147750 ACA1_147750 ACA1_106950 ACA1_106950 ACA1_271290 ACA1_271290 ACA1_271370 ACA1_271370 ACA1_380800 ACA1_380800 ACA1_391070 ACA1_391070 ACA1_130550 ACA1_130550 ACA1_325150 ACA1_325150 ACA1_325260 ACA1_325260 ACA1_215300 ACA1_215300 ACA1_139430 ACA1_139430 ACA1_213340 ACA1_213340 ACA1_392150 ACA1_392150 ACA1_275430 ACA1_275430 ACA1_219760 ACA1_219760 ACA1_164860 ACA1_164860 ACA1_391520 ACA1_391520 ACA1_377960 ACA1_377960 ACA1_325160 ACA1_325160 ACA1_216930 ACA1_216930 ACA1_177890 ACA1_177890 ACA1_331360 ACA1_331360 ACA1_088920 ACA1_088920 ACA1_204500 ACA1_204500 ACA1_043350 ACA1_043350 ACA1_382900 ACA1_382900 ACA1_087610 ACA1_087610 ACA1_090060 ACA1_090060 ACA1_066000 ACA1_066000 ACA1_066100 ACA1_066100 ACA1_064210 ACA1_064210 ACA1_383740 ACA1_383740 ACA1_132870 ACA1_132870 ACA1_057240 ACA1_057240 ACA1_371680 ACA1_371680 ACA1_063700 ACA1_063700 ACA1_064250 ACA1_064250 ACA1_234070 ACA1_234070 ACA1_040760 ACA1_040760 ACA1_036890 ACA1_036890 ACA1_167070 ACA1_167070 ACA1_368170 ACA1_368170 ACA1_265330 ACA1_265330 ACA1_267900 ACA1_267900 ACA1_040840 ACA1_040840 ACA1_040890 ACA1_040890 ACA1_265400 ACA1_265400 ACA1_045270 ACA1_045270 ACA1_197490 ACA1_197490 ACA1_045590 ACA1_045590 ACA1_234760 ACA1_234760 ACA1_200240 ACA1_200240 ACA1_201450 ACA1_201450 ACA1_133210 ACA1_133210 ACA1_206060 ACA1_206060 ACA1_113940 ACA1_113940 ACA1_054710 ACA1_054710 ACA1_055010 ACA1_055010 ACA1_279420 ACA1_279420 ACA1_183900 ACA1_183900 ACA1_055290 ACA1_055290 ACA1_181930 ACA1_181930 ACA1_277410 ACA1_277410 ACA1_384530 ACA1_384530 ACA1_385460 ACA1_385460 ACA1_277970 ACA1_277970 ACA1_228930 ACA1_228930 ACA1_181830 ACA1_181830 ACA1_253150 ACA1_253150 ACA1_158440 ACA1_158440 ACA1_125940 ACA1_125940 ACA1_384010 ACA1_384010 ACA1_328080 ACA1_328080 ACA1_007760 ACA1_007760 ACA1_384340 ACA1_384340 ACA1_126690 ACA1_126690 ACA1_149260 ACA1_149260 ACA1_070500 ACA1_070500 ACA1_070580 ACA1_070580 ACA1_071690 ACA1_071690 ACA1_149540 ACA1_149540 ACA1_075020 ACA1_075020 ACA1_068070 ACA1_068070 ACA1_071350 ACA1_071350 ACA1_072100 ACA1_072100 ACA1_070490 ACA1_070490 ACA1_376480 ACA1_376480 ACA1_171680 ACA1_171680 ACA1_075010 ACA1_075010 ACA1_175130 ACA1_175130 ACA1_074580 ACA1_074580 ACA1_172100 ACA1_172100 ACA1_309800 ACA1_309800 ACA1_287560 ACA1_287560 ACA1_289900 ACA1_289900 ACA1_333210 ACA1_333210 ACA1_287220 ACA1_287220 ACA1_084890 ACA1_084890 ACA1_294900 ACA1_294900
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACA1_145230Kinesin motor domain containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1184 aa)
ACA1_387900ADPribosylation factor 1, putative; Belongs to the small GTPase superfamily. Arf family. (181 aa)
ACA1_048130Charged multivesicular body protein, putative. (213 aa)
ACA1_121520Charged multivesicular body protein 2a 2 family protein. (299 aa)
ACA1_261570Sec7 domain containing protein. (359 aa)
ACA1_362710ADPribosylation factor, putative; Belongs to the small GTPase superfamily. Arf family. (173 aa)
ACA1_260070Vacuolar protein sorting-associated protein 29; Belongs to the VPS29 family. (613 aa)
ACA1_387860High molecular weight heat shock protein; Belongs to the heat shock protein 70 family. (666 aa)
ACA1_139840Receptor mediated endocytosis family member (Rme1), putative; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (502 aa)
ACA1_374380Heat shock protein ssa1, putative; Belongs to the heat shock protein 70 family. (622 aa)
ACA1_101500PH domain containing protein. (915 aa)
ACA1_256400Ras subfamily protein. (237 aa)
ACA1_373890Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (361 aa)
ACA1_399850Ras family protein. (228 aa)
ACA1_092970ADPribosylation factor 1, putative; Belongs to the small GTPase superfamily. Arf family. (184 aa)
ACA1_093490GTPase activating protein. (389 aa)
ACA1_097740PH domain containing protein. (1096 aa)
ACA1_091160Phospholipase D, putative. (934 aa)
ACA1_096470Dual specificity phosphatase, catalytic domain containing protein. (738 aa)
ACA1_246860Likely rab family GTPbinding protein. (221 aa)
ACA1_120810Phosphatidylinositol-4-phosphate 5-Kinase. (855 aa)
ACA1_359270RAB family member (Rab7), putative. (206 aa)
ACA1_364700Ras family protein. (217 aa)
ACA1_366160Vacuolar protein sortingassociated protein 45, putative; Belongs to the STXBP/unc-18/SEC1 family. (557 aa)
ACA1_366670Kinesin motor domain containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (813 aa)
ACA1_147750Phospholipase D active site domain containing protein. (1564 aa)
ACA1_106950PH domain containing protein. (591 aa)
ACA1_271290Uncharacterized protein. (228 aa)
ACA1_271370Phosphatidylinositol4-phosphate 5-Kinase. (820 aa)
ACA1_380800AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (143 aa)
ACA1_391070Arf-GAP domain-containing protein. (185 aa)
ACA1_130550WH2 motif domain containing protein. (487 aa)
ACA1_325150Rab7/RabGfamily small GTPase. (205 aa)
ACA1_325260Peptidylprolyl isomerase. (1517 aa)
ACA1_215300Phosphatidylinositol4-phosphate 5-Kinase protein. (863 aa)
ACA1_139430Kinesin motor domain containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1025 aa)
ACA1_213340Vacuolar proteinsorting-associated protein 25, putative. (151 aa)
ACA1_392150ATPase, AAA domain containing protein; Belongs to the AAA ATPase family. (491 aa)
ACA1_275430ENTH domain containing protein. (503 aa)
ACA1_219760Uncharacterized protein. (1194 aa)
ACA1_164860Ras subfamily protein. (181 aa)
ACA1_391520SNF7 family protein. (425 aa)
ACA1_377960Uncharacterized protein. (492 aa)
ACA1_325160Rab7/RabGfamily small GTPase. (186 aa)
ACA1_216930Rab11/RabAfamily small GTPase. (186 aa)
ACA1_177890Phosphatidylinositol4-phosphate 5-Kinase. (674 aa)
ACA1_331360EAP30/Vps36 family protein. (317 aa)
ACA1_088920Phorbol esters/diacylglycerol binding domain containing protein. (1319 aa)
ACA1_204500Uncharacterized protein. (1926 aa)
ACA1_043350F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (301 aa)
ACA1_382900ADPribosylation factor, putative; Belongs to the small GTPase superfamily. Arf family. (186 aa)
ACA1_087610Phospholipase D, putative. (1821 aa)
ACA1_090060Ras subfamily protein. (567 aa)
ACA1_066000Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (293 aa)
ACA1_066100Arf GTPase activating protein. (576 aa)
ACA1_064210Phospholipase D active site domain containing protein. (635 aa)
ACA1_383740GTPbinding protein YPTC5, putative. (197 aa)
ACA1_132870Chromatin modifying protein 1b, putative. (194 aa)
ACA1_057240MIT domain containing protein. (612 aa)
ACA1_371680BAR domain containing protein. (417 aa)
ACA1_063700Vacuolarsorting protein SNF7, putative. (224 aa)
ACA1_064250AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (1055 aa)
ACA1_234070ELL complex EAP30 subunit. (208 aa)
ACA1_040760SNF7 family protein. (204 aa)
ACA1_036890Ras subfamily protein. (207 aa)
ACA1_167070Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1716 aa)
ACA1_368170Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (127 aa)
ACA1_265330F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (280 aa)
ACA1_267900Brefeldin A resistance factor, putative. (584 aa)
ACA1_040840Programmed cell death 6 interacting protein, putative. (835 aa)
ACA1_040890Rabtype small GTP-binding protein. (192 aa)
ACA1_265400Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (822 aa)
ACA1_045270Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (201 aa)
ACA1_197490Uncharacterized protein. (688 aa)
ACA1_045590Arf GTPase activating protein. (157 aa)
ACA1_234760WH1 domain containing protein. (478 aa)
ACA1_200240Phospholipase D active site domain containing protein. (1137 aa)
ACA1_201450ADPribosylation factor, putative; Belongs to the small GTPase superfamily. Arf family. (181 aa)
ACA1_133210SH3 domain containing protein. (419 aa)
ACA1_206060Ras subfamily protein. (259 aa)
ACA1_113940WASH complex subunit 7 family protein. (1141 aa)
ACA1_054710Ras family protein. (128 aa)
ACA1_055010Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (660 aa)
ACA1_279420BAR domain containing protein. (300 aa)
ACA1_183900Phosphatidylinositol phosphate kinase PIPK5, putative. (707 aa)
ACA1_055290Sec7 domain containing protein. (592 aa)
ACA1_181930GRAM domain containing protein. (1479 aa)
ACA1_277410SH3 domain containing protein. (415 aa)
ACA1_384530Uncharacterized protein. (360 aa)
ACA1_385460PH domain containing protein. (858 aa)
ACA1_277970Vacuolar protein sortingassociated protein 26, putative. (339 aa)
ACA1_228930Vta1 domain-containing protein. (490 aa)
ACA1_181830Phosphatidylinositol4 phosphate 5-kinase, putative. (1134 aa)
ACA1_253150RAB8D, putative. (223 aa)
ACA1_158440Coiled-coil domain containing 53, putative. (217 aa)
ACA1_125940Phosphatidylinositol-4-phosphate 5-Kinase. (775 aa)
ACA1_384010Arf GTPase activating protein. (434 aa)
ACA1_328080Rab GTPase, putative. (228 aa)
ACA1_007760PH domain containing protein. (1266 aa)
ACA1_384340Ras subfamily protein. (207 aa)
ACA1_126690Phosphatidylinositol4-phosphate Kinase. (486 aa)
ACA1_149260Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (160 aa)
ACA1_070500Ras subfamily protein. (211 aa)
ACA1_070580Vps23 domain containing protein. (287 aa)
ACA1_071690Vacuolar protein sorting factor 4, putative; Belongs to the AAA ATPase family. (415 aa)
ACA1_149540Vacuolar protein sorting. (210 aa)
ACA1_075020Rab7, putative. (200 aa)
ACA1_068070Small GTPbinding ADP-ribosylation factor; Belongs to the small GTPase superfamily. Arf family. (227 aa)
ACA1_071350GTPbinding ADP-ribosylation factor Arf1, putative; Belongs to the small GTPase superfamily. Arf family. (180 aa)
ACA1_072100Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (297 aa)
ACA1_070490Phospholipase D, putative. (1437 aa)
ACA1_376480RabE family small GTPase. (155 aa)
ACA1_171680PX domain containing protein. (504 aa)
ACA1_075010Ras family protein. (187 aa)
ACA1_175130Rab8/RabEfamily small GTPase, putative. (208 aa)
ACA1_074580Rasrelated protein Rab-7, putative. (186 aa)
ACA1_172100Phosphatidylinositol4-phosphate 5-Kinase. (750 aa)
ACA1_309800Variant sh3 domain containing protein. (432 aa)
ACA1_287560AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
ACA1_289900RAB11B protein, putative. (213 aa)
ACA1_333210F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (277 aa)
ACA1_287220Phospholipase D active site domain containing protein. (1125 aa)
ACA1_084890ADPribosylation factor, putative; Belongs to the small GTPase superfamily. Arf family. (179 aa)
ACA1_294900Cytohesin 2, putative. (1893 aa)
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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