STRINGSTRING
gyrA_2 gyrA_2 gyrB_2 gyrB_2 recF recF rpmH rpmH soj_2 soj_2 spo0C spo0C KJQ52580.1 KJQ52580.1 rpsF rpsF rpsR1 rpsR1 dnaB dnaB msmE_7 msmE_7 liaR_8 liaR_8 KJQ52698.1 KJQ52698.1 KJQ52700.1 KJQ52700.1 KJQ52772.1 KJQ52772.1 KJQ52781.1 KJQ52781.1 msmE_8 msmE_8 msmE_9 msmE_9 rpmB rpmB rpmG2 rpmG2 hup hup rpsN rpsN KJQ56079.1 KJQ56079.1 recQ_1 recQ_1 tmk_1 tmk_1 rplT rplT rpmI rpmI cutC cutC sdh_1 sdh_1 dapH_1 dapH_1 cobB cobB hrpB_1 hrpB_1 KJQ55761.1 KJQ55761.1 KJQ55725.1 KJQ55725.1 KJQ55625.1 KJQ55625.1 dksA dksA obg obg KJQ55512.1 KJQ55512.1 rpsT rpsT recO recO dnaG dnaG KJQ55432.1 KJQ55432.1 KJQ55468.1 KJQ55468.1 crtN crtN yedK yedK KJQ55317.1 KJQ55317.1 topA topA KJQ55355.1 KJQ55355.1 KJQ55356.1 KJQ55356.1 KJQ55361.1 KJQ55361.1 recR recR ulaF ulaF KJQ55151.1 KJQ55151.1 KJQ55200.1 KJQ55200.1 rplL_1 rplL_1 KJQ55235.1 KJQ55235.1 KJQ55009.1 KJQ55009.1 rpsI rpsI rplM rplM recN recN soj_1 soj_1 parA parA spk1 spk1 KJQ54922.1 KJQ54922.1 KJQ54933.1 KJQ54933.1 rplU rplU rpmE2 rpmE2 pdxS pdxS KJQ54744.1 KJQ54744.1 rarA rarA priA_2 priA_2 yesO_1 yesO_1 KJQ54517.1 KJQ54517.1 rplY rplY KJQ54590.1 KJQ54590.1 liaR_3 liaR_3 KJQ54261.1 KJQ54261.1 KJQ54265.1 KJQ54265.1 KJQ54353.1 KJQ54353.1 yesO_3 yesO_3 kynU_1 kynU_1 legI legI rpsG rpsG rpsJ rpsJ rplC rplC rplW rplW rplB rplB rpsC rpsC rpmC rpmC rpsQ rpsQ rplN rplN rplX rplX rplE rplE rpsH rpsH rplR rplR rpsE rpsE rpmD rpmD rplO rplO rpmJ rpmJ rpsK rpsK rplQ rplQ KJQ54098.1 KJQ54098.1 rplJ rplJ rplL_2 rplL_2 msmE_3 msmE_3 ccsA ccsA KJQ53775.1 KJQ53775.1 ykgO ykgO lpxD lpxD yvyD yvyD recQ_2 recQ_2 KJQ53337.1 KJQ53337.1 rlp2 rlp2 msmE_5 msmE_5 KJQ52920.1 KJQ52920.1 rpsB rpsB rpsP rpsP smc_2 smc_2 rpmF rpmF KJQ53005.1 KJQ53005.1 KJQ53015.1 KJQ53015.1 rpsO rpsO msmE_6 msmE_6 opuCB opuCB recQ_3 recQ_3 KJQ52510.1 KJQ52510.1 pknB pknB
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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gyrA_2DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (850 aa)
gyrB_2DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (694 aa)
recFDNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (408 aa)
rpmH50S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. (45 aa)
soj_2Sporulation initiation inhibitor protein Soj. (308 aa)
spo0CChromosome-partitioning protein Spo0J; Belongs to the ParB family. (322 aa)
KJQ52580.1Hypothetical protein. (724 aa)
rpsF30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (125 aa)
rpsR130S ribosomal protein S18 1; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (84 aa)
dnaBReplicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (457 aa)
msmE_7Multiple sugar-binding protein precursor. (451 aa)
liaR_8Transcriptional regulatory protein LiaR. (938 aa)
KJQ52698.1Putative trans-acting enoyl reductase. (380 aa)
KJQ52700.1Putative HTH-type transcriptional regulator. (955 aa)
KJQ52772.1Bacterial extracellular solute-binding protein. (457 aa)
KJQ52781.1Formiminotransferase-cyclodeaminase. (206 aa)
msmE_8Multiple sugar-binding protein precursor. (429 aa)
msmE_9Multiple sugar-binding protein precursor. (441 aa)
rpmB50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family. (78 aa)
rpmG250S ribosomal protein L33 2; Belongs to the bacterial ribosomal protein bL33 family. (56 aa)
hupDNA-binding protein HU; Belongs to the bacterial histone-like protein family. (95 aa)
rpsN30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (101 aa)
KJQ56079.1CHAT domain protein. (816 aa)
recQ_1ATP-dependent DNA helicase RecQ. (708 aa)
tmk_1Thymidylate kinase. (214 aa)
rplT50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (128 aa)
rpmI50S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family. (70 aa)
cutCCopper homeostasis protein CutC; Participates in the control of copper homeostasis. Belongs to the CutC family. (253 aa)
sdh_1Serine 3-dehydrogenase. (259 aa)
dapH_12,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase. (178 aa)
cobBNAD-dependent protein deacetylase. (279 aa)
hrpB_1ATP-dependent RNA helicase HrpB. (824 aa)
KJQ55761.1Hypothetical protein. (407 aa)
KJQ55725.1Hypothetical protein. (996 aa)
KJQ55625.1Glycerol-3-phosphate transporter periplasmic binding protein. (414 aa)
dksARNA polymerase-binding transcription factor DksA. (117 aa)
obgGTPase Obg. (287 aa)
KJQ55512.1Hypothetical protein. (291 aa)
rpsT30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. (86 aa)
recODNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. (247 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (619 aa)
KJQ55432.1Phosphotransferase enzyme family protein. (245 aa)
KJQ55468.1Archaeal ATPase. (389 aa)
crtNDehydrosqualene desaturase. (533 aa)
yedKPutative SOS response-associated peptidase YedK. (208 aa)
KJQ55317.1Hypothetical protein. (434 aa)
topADNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (967 aa)
KJQ55355.1Bacterial type II secretion system protein F domain protein. (300 aa)
KJQ55356.1Putative conjugal transfer protein. (336 aa)
KJQ55361.1Phosphodiesterase YaeI. (313 aa)
recRRecombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (197 aa)
ulaFL-ribulose-5-phosphate 4-epimerase UlaF. (239 aa)
KJQ55151.1Maltose ABC transporter periplasmic protein. (445 aa)
KJQ55200.1Hypothetical protein. (514 aa)
rplL_150S ribosomal protein L7/L12. (186 aa)
KJQ55235.1HhH-GPD superfamily base excision DNA repair protein. (206 aa)
KJQ55009.1Putative thiazole biosynthetic enzyme. (483 aa)
rpsI30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (161 aa)
rplM50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (148 aa)
recNDNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (557 aa)
soj_1Sporulation initiation inhibitor protein Soj. (296 aa)
parAChromosome partitioning protein ParA. (270 aa)
spk1Serine/threonine-protein kinase PK-1. (643 aa)
KJQ54922.130S ribosomal protein S1 homolog. (484 aa)
KJQ54933.1Hypothetical protein. (112 aa)
rplU50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (102 aa)
rpmE250S ribosomal protein L31 type B. (86 aa)
pdxSPyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (297 aa)
KJQ54744.1Hypothetical protein. (450 aa)
rarAReplication-associated recombination protein A. (457 aa)
priA_2Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (652 aa)
yesO_1Putative ABC transporter substrate-binding protein YesO. (448 aa)
KJQ54517.1Hypothetical protein. (155 aa)
rplY50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (209 aa)
KJQ54590.1Putative conjugal transfer protein. (397 aa)
liaR_3Transcriptional regulatory protein LiaR. (147 aa)
KJQ54261.1Hypothetical protein. (319 aa)
KJQ54265.1Ski2-like helicase. (849 aa)
KJQ54353.1Bacterial extracellular solute-binding protein. (360 aa)
yesO_3Putative ABC transporter substrate-binding protein YesO. (431 aa)
kynU_1Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (421 aa)
legIN,N'-diacetyllegionaminic acid synthase. (290 aa)
rpsG30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (157 aa)
rpsJ30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (163 aa)
rplC50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (219 aa)
rplW50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (107 aa)
rplB50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (279 aa)
rpsC30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (251 aa)
rpmC50S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (105 aa)
rpsQ30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (110 aa)
rplN50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa)
rplX50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (119 aa)
rplE50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (196 aa)
rpsH30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (132 aa)
rplR50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (119 aa)
rpsE30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (238 aa)
rpmD50S ribosomal protein L30. (61 aa)
rplO50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (222 aa)
rpmJ50S ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family. (38 aa)
rpsK30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (132 aa)
rplQ50S ribosomal protein L17. (188 aa)
KJQ54098.1Hypothetical protein. (144 aa)
rplJ50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (162 aa)
rplL_250S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (125 aa)
msmE_3Multiple sugar-binding protein precursor. (439 aa)
ccsACytochrome c biogenesis protein CcsA. (325 aa)
KJQ53775.1Hypothetical protein. (58 aa)
ykgO50S ribosomal protein L36 2; Belongs to the bacterial ribosomal protein bL36 family. (40 aa)
lpxDUDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase. (200 aa)
yvyDPutative sigma-54 modulation protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. (218 aa)
recQ_2ATP-dependent DNA helicase RecQ. (689 aa)
KJQ53337.1Hypothetical protein. (260 aa)
rlp2Ribulose bisphosphate carboxylase-like protein 2; Belongs to the RuBisCO large chain family. (418 aa)
msmE_5Multiple sugar-binding protein precursor. (447 aa)
KJQ52920.1Hypothetical protein. (193 aa)
rpsB30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (331 aa)
rpsP30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. (144 aa)
smc_2Chromosome partition protein Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1181 aa)
rpmF50S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. (69 aa)
KJQ53005.1ATP-dependent protease La (LON) domain protein. (198 aa)
KJQ53015.1Eukaryotic DNA topoisomerase I, catalytic core. (337 aa)
rpsO30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (89 aa)
msmE_6Multiple sugar-binding protein precursor. (414 aa)
opuCBGlycine betaine/carnitine/choline transport system permease protein OpuCB. (243 aa)
recQ_3ATP-dependent DNA helicase RecQ. (546 aa)
KJQ52510.1Hypothetical protein. (189 aa)
pknBSerine/threonine-protein kinase PknB. (563 aa)
Your Current Organism:
Microbacterium sp. SA39
NCBI taxonomy Id: 1263625
Other names: M. sp. SA39
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