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| | F543_3150 | L-asparaginase II PRK11096; L-asparaginase of Bacteria UniRef RepID=C6AJK5_AGGAN; Belongs to the asparaginase 1 family. (349 aa) |
| | argS | arginyl-tRNA synthetase PRK12451; Arginyl-tRNA synthetase of Proteobacteria UniRef RepID=SYR_NEIG2. (575 aa) |
| | dapE | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (375 aa) |
| | folP | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (258 aa) |
| | F543_2750 | Biotin carboxylase COG0439; Phosphoribosylglycinamide synthetase of Bacteria UniRef RepID=A6VP22_ACTSZ. (392 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (255 aa) |
| | glnA | Glutamine synthetase PRK09469; Glutamine synthetase of cellular organisms UniRef RepID=GLNA_SYNY3. (523 aa) |
| | AHG85217.1 | Beta-lactamase domain protein of Actinobacillus succinogenes 130Z UniRef RepID=A6VPW2_ACTSZ. (339 aa) |
| | AHG85215.1 | GloB protein of Bacteria UniRef RepID=Q65QZ2_MANSM. (337 aa) |
| | AHG85189.1 | Hypothetical protein; Predicted Zn-dependent hydrolases of the beta-lactamase fold COG2220; uncharacterized protein of Mannheimia succiniciproducens MBEL55E UniRef RepID=Q65SM5_MANSM. (370 aa) |
| | putA | 1-pyrroline-5-carboxylate dehydrogenase /proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1198 aa) |
| | lldD | L-lactate dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. (381 aa) |
| | AHG85170.1 | PykF protein; 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase COG3836; PykF protein of Pasteurellaceae UniRef RepID=Q65QQ0_MANSM; Belongs to the HpcH/HpaI aldolase family. (263 aa) |
| | F543_230 | Methylmalonate-semialdehyde dehydrogenase of Proteobacteria UniRef RepID=Q0K5K0_CUPNH. (504 aa) |
| | sul2 | Dihydropteroate synthase type-2; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (342 aa) |
| | slyX | Protein slyX of Gammaproteobacteria UniRef RepID=SLYX_MANSM; Belongs to the SlyX family. (86 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (274 aa) |
| | AHG85072.1 | L-ascorbate 6-phosphate lactonase PRK11709; Probable L-ascorbate-6-phosphate lactonase ulaG of Bacteria UniRef RepID=ULAG_SALA4. (379 aa) |
| | trpS | Tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (342 aa) |
| | ispH | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (314 aa) |
| | AHG85048.1 | UPF0350 protein; Uncharacterized conserved protein COG2938; UPF0350 protein HD_0065 of Pasteurellaceae UniRef RepID=Y065_HAEDU. (81 aa) |
| | AHG85043.1 | L-2,4-diaminobutyrate decarboxylase of Bacteria UniRef RepID=B0BU02_ACTPJ. (510 aa) |
| | folB | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (116 aa) |
| | AHG85021.1 | FAD/FMN-containing dehydrogenases COG0277; FAD/FMN dehydrogenase of Pasteurellaceae UniRef RepID=E8KKP8_9PAST. (1017 aa) |
| | fabA | 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (176 aa) |
| | AHG84994.1 | Aldo/keto reductases, to diketogulonate reductase COG0656; Aldo/keto reductase of Aggregatibacter actinomycetemcomitans UniRef RepID=C9R2N9_AGGAD. (280 aa) |
| | fabR | DNA-binding transcriptional repressor FabR PRK11202; HTH-type transcriptional repressor fabR of Bacteria UniRef RepID=FABR_ECO24. (206 aa) |
| | dtd | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (144 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (414 aa) |
| | proS | Prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (571 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (76 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1320 aa) |
| | epmA | Protein YjeA; With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P; Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily. (327 aa) |
| | glyQ | glycyl-tRNA synthetase subunit alpha PRK09348; Glycyl-tRNA synthetase alpha subunit of cellular organisms UniRef RepID=SYGA_PSEA6. (327 aa) |
| | glyS | glycyl-tRNA synthetase subunit beta PRK01233; Glycyl-tRNA synthetase beta subunit of Bacteria UniRef RepID=SYGB_HAEI8. (726 aa) |
| | asnA | Aspartate--ammonia ligase; Asparagine synthetase AsnA PRK05425; Aspartate--ammonia ligase of cellular organisms UniRef RepID=ASNA_HAEIE. (330 aa) |
| | frdD | Reductase; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (114 aa) |
| | AHG84862.1 | D-3-phosphoglycerate dehydrogenase PRK11790; D-3-phosphoglycerate dehydrogenase of Bacteria UniRef RepID=SERA_HAEIN; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (409 aa) |
| | fabD | Malonyl CoA-acyl carrier protein transacylase of root UniRef RepID=FABD_HAEIN. (311 aa) |
| | fabG | 3-ketoacyl-(Acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (242 aa) |
| | valS | Valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (948 aa) |
| | cysK | Cysteine synthase A PRK10717; Cysteine synthase of Bacteria UniRef RepID=Q482P1_COLP3; Belongs to the cysteine synthase/cystathionine beta- synthase family. (316 aa) |
| | AHG84815.1 | BcbE of Proteobacteria UniRef RepID=Q9L9L0_PASMD. (240 aa) |
| | AHG84800.1 | Phosphate acyltransferase PRK05331; Phosphate acyltransferase of Pasteurellaceae UniRef RepID=PLSX_ACTP2. (118 aa) |
| | plsX | Phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (188 aa) |
| | dapD | 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase PRK11830; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase of root UniRef RepID=DAPD_NEIG1; Belongs to the transferase hexapeptide repeat family. (291 aa) |
| | ald | Alanine dehydrogenase COG0686; Alanine dehydrogenase of Helicobacter bilis ATCC 43879 UniRef RepID=C3XDW9_9HELI; Belongs to the AlaDH/PNT family. (371 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (146 aa) |
| | AHG84788.1 | Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (155 aa) |
| | accC | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa) |
| | nrfC | Reductase; Formate-dependent nitrite reductase complex, Fe-S protein of Proteobacteria UniRef RepID=Q7MM21_VIBVY. (228 aa) |
| | tyrS | Tyrosyl-tRNA synthetase 2; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (396 aa) |
| | AHG84752.1 | HIT-like protein; Purine nucleoside phosphoramidase PRK10687; HIT-like protein HI_0961 of Bacteria UniRef RepID=Y961_HAEIN. (119 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (298 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (432 aa) |
| | hisC-2 | Histidinol-phosphate aminotransferase PRK01688; Histidinol-phosphate aminotransferase of Bacteria UniRef RepID=HIS8_YERE8; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (353 aa) |
| | hisB | Histidine biosynthesis bifunctional protein hisB; Imidazole glycerol-phosphate dehydratase/histidinol phosphatase PRK05446; Histidine biosynthesis bifunctional protein hisB of Bacteria UniRef RepID=HIS7_ACTSZ; In the N-terminal section; belongs to the histidinol- phosphatase family. (362 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (197 aa) |
| | hisA | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase PRK00748; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase of Bacteria UniRef RepID=HIS4_ACTP2. (249 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (257 aa) |
| | hisI | Histidine biosynthesis bifunctional protein HisIE; Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein PRK02759; Histidine biosynthesis bifunctional protein HisIE of Bacteria UniRef RepID=HIS2_HAEIN; In the N-terminal section; belongs to the PRA-CH family. (212 aa) |
| | AHG84725.1 | Serine acetyltransferase PRK11132; Serine acetyltransferase of cellular organisms UniRef RepID=B4F141_PROMH; overlaps CDS with the same product name. (233 aa) |
| | ilvD | Dihydroxy-acid dehydratase PRK12448; Dihydroxy-acid dehydratase of Bacteria UniRef RepID=D8IY91_HERSS; Belongs to the IlvD/Edd family. (597 aa) |
| | metG | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (493 aa) |
| | AHG84697.1 | methionyl-tRNA synthetase PRK00133; Methionyl-tRNA synthetase of root UniRef RepID=SYM_VIBC3; overlaps CDS with the same product name. (199 aa) |
| | fadR | Fatty acid metabolism regulator protein; Multifunctional regulator of fatty acid metabolism. (240 aa) |
| | metE | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (756 aa) |
| | ileS | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (933 aa) |
| | argH | Argininosuccinate lyase PRK04833; Argininosuccinate lyase of cellular organisms UniRef RepID=ARLY_TOLAT. (472 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (544 aa) |
| | cysZ | Cysteine synthetase; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway; Belongs to the CysZ family. (276 aa) |
| | gnd | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (484 aa) |
| | pheA | Bifunctional chorismate mutase/prephenate dehydratase PRK10622; Bifunctional prephenate dehydratase/chorismate mutase of Gammaproteobacteria UniRef RepID=B8F6C2_HAEPS. (385 aa) |
| | msbB | Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A. (551 aa) |
| | argR | Arginine repressor; Regulates arginine biosynthesis genes. (140 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (314 aa) |
| | argD | Acetylornithine aminotransferase PRK02627; Acetylornithine aminotransferase of Haemophilus ducreyi 35000HP UniRef RepID=ARGD_HAEDU; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (393 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (290 aa) |
| | argJ | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (406 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. (314 aa) |
| | gloA | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (129 aa) |
| | ispG | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (369 aa) |
| | hisS | histidyl-tRNA synthetase PRK00037; Histidyl-tRNA synthetase of Gammaproteobacteria UniRef RepID=SYH_MANSM. (428 aa) |
| | pgk | Phosphoglycerate kinase PRK00073; Phosphoglycerate kinase of Aggregatibacter actinomycetemcomitans UniRef RepID=G4ACN5_AGGAC; Belongs to the phosphoglycerate kinase family. (385 aa) |
| | AHG84470.1 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (359 aa) |
| | pdxT | Glutamine amidotransferase subunit pdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (188 aa) |
| | ttrB | Reductase; Tetrathionate reductase subunit B PRK14993; Tetrathionate reductase subunit B of Proteobacteria UniRef RepID=A7JTF2_PASHA. (241 aa) |
| | AHG84432.1 | Uncharacterized protein of Pasteurellaceae UniRef RepID=A3N009_ACTP2. (59 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (321 aa) |
| | AHG84422.1 | Cysteine sulfinate desulfinase PRK10874; Probable cysteine desulfurase of Pasteurellaceae UniRef RepID=CSD_HAEIN. (398 aa) |
| | AHG84388.1 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (252 aa) |
| | AHG84366.1 | acetyl-CoA:acetoacetyl-CoA transferase subunit alpha PRK09920; Acetate CoA-transferase subunit alpha of Bacteria UniRef RepID=ATOD_HAEIN. (215 aa) |
| | AHG84365.1 | Acetate CoA-transferase subunit beta of Bacteria UniRef RepID=ATOA_HAEIN. (219 aa) |
| | iolD | IolD; Acetolactate synthase COG3962; IolD of Bacteria UniRef RepID=D4GD77_PANAM; Belongs to the TPP enzyme family. (644 aa) |
| | AHG84363.1 | Acyltransferase PRK05790; Acetyl-CoA acetyltransferase of cellular organisms UniRef RepID=THIL_CUPNH; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa) |
| | trpF | Tryptophan biosynthesis protein TrpCF; Bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase PRK09427; Tryptophan biosynthesis protein TrpCF of Gammaproteobacteria UniRef RepID=TRPC_HAEIN. (471 aa) |
| | F543_1490 | SCP-2 sterol transfer; Uncharacterized protein conserved in bacteria COG3165; SCP-2 sterol transfer family protein of Pasteurellaceae UniRef RepID=E8KJJ8_9PAST. (208 aa) |
| | alr | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (374 aa) |
| | AHG84341.1 | aspartyl-tRNA synthetase PRK00476; Aspartyl-tRNA synthetase of Buchnera aphidicola UniRef RepID=SYD_BUCBP; overlaps CDS with the same product name. (165 aa) |
| | aspS | Aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (424 aa) |
| | glsA | Glutaminase PRK00971; Glutaminase of Bacteroidetes UniRef RepID=A3U907_CROAH; Belongs to the glutaminase family. (305 aa) |
| | lpxL | Lipid A acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). (313 aa) |
| | AHG84333.1 | Probable NADP-dependent dehydrogenase HI_1430 of Bacteria UniRef RepID=Y1430_HAEIN; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (250 aa) |
| | leuD | 3-isopropylmalate dehydratase large subunit-like protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (219 aa) |
| | leuC | 3-isopropylmalate dehydratase large subunit-like protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (468 aa) |
| | trpB | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (390 aa) |
| | trpA | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (270 aa) |
| | gpmA | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (227 aa) |
| | metXA | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (362 aa) |
| | F543_1420 | long-chain-fatty-acid--CoA ligase; Long-chain acyl-CoA synthetases (AMP-forming) COG1022; long-chain-fatty-acid--CoA ligase of Bacteria UniRef RepID=LCFH_HAEIN. (593 aa) |
| | AHG84271.1 | 3-ketoacyl-CoA thiolase PRK08963; Acetyl-CoA acetyltransferase of Pasteurellaceae UniRef RepID=B0BPH2_ACTPJ; Belongs to the thiolase-like superfamily. Thiolase family. (434 aa) |
| | AHG84270.1 | Multifunctional fatty acid oxidation complex subunit alpha PRK11154; Fatty oxidation complex, alpha subunit of Haemophilus parasuis UniRef RepID=B8F4S2_HAEPS; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (714 aa) |
| | nanA | N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. (293 aa) |
| | epmB | KamA; Uncharacterized KamA family protein HI_0329 of Gammaproteobacteria UniRef RepID=Y329_HAEIN. (336 aa) |
| | pheS | phenylalanyl-tRNA synthetase subunit alpha PRK00488; Phenylalanyl-tRNA synthetase alpha chain of Gammaproteobacteria UniRef RepID=SYFA_HAES1; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (327 aa) |
| | pheT | phenylalanyl-tRNA synthetase subunit beta PRK00629; Phenylalanyl-tRNA synthetase beta chain of cellular organisms UniRef RepID=SYFB_HAEDU; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (795 aa) |
| | accA | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa) |
| | ispE | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (280 aa) |
| | AHG84221.1 | Bifunctional folylpolyglutamate synthase/ dihydrofolate synthase PRK10846; Folylpolyglutamate synthase of Bacteria UniRef RepID=FOLC_HAEIN; Belongs to the folylpolyglutamate synthase family. (432 aa) |
| | accD | Acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (298 aa) |
| | AHG84211.1 | Predicted glutamine amidotransferase COG0121; Class II glutamine amidotransferase domain protein of Pasteurellaceae UniRef RepID=F9Q659_9PAST. (86 aa) |
| | AHG84210.1 | Predicted glutamine amidotransferase COG0121; glutamine amidotransferase HI_1037 of Pasteurellaceae UniRef RepID=Y1037_HAEIN. (161 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (298 aa) |
| | folD | Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (283 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (367 aa) |
| | AHG84189.1 | Glutamate dehydrogenase PRK09414; Glutamate dehydrogenase of Proteobacteria UniRef RepID=Q46UV2_CUPPJ; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (449 aa) |
| | fdxH | Formate dehydrogenase iron-sulfur subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (299 aa) |
| | lysS | lysyl-tRNA synthetase PRK00484; Lysyl-tRNA synthetase of Gammaproteobacteria UniRef RepID=SYK_COLP3; Belongs to the class-II aminoacyl-tRNA synthetase family. (500 aa) |
| | dmsB | Reductase; Probable anaerobic dimethyl sulfoxide reductase chain ynfG of Enterobacteriaceae UniRef RepID=YNFG_ECOL6. (206 aa) |
| | AHG84126.1 | Reductase; Enoyl-(acyl carrier protein) reductase PRK07984; Enoyl-[acyl-carrier-protein] reductase [NADH] FabI of root UniRef RepID=FABI_HAEIN. (260 aa) |
| | AHG84119.1 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (357 aa) |
| | lysC | Aspartate kinase III PRK09084; Lysine-sensitive aspartokinase 3 of Bacteria UniRef RepID=AK3_ECOLI; Belongs to the aspartokinase family. (450 aa) |
| | serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (287 aa) |
| | AHG84111.1 | 3-phosphoserine/phosphohydroxythreonine aminotransferase PRK05355; Phosphoserine aminotransferase of Aggregatibacter UniRef RepID=C9R5R8_AGGAD. (65 aa) |
| | AHG84101.1 | Amidophosphoribosyltransferase PRK07272; Amidophosphoribosyltransferase of cellular organisms UniRef RepID=PUR1_STAAR; overlaps CDS with the same product name. (88 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (405 aa) |
| | hisC | Histidinol-phosphate aminotransferase PRK02731; Histidinol-phosphate aminotransferase 1 of Proteobacteria UniRef RepID=HIS81_MANSM; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (365 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (431 aa) |
| | dld | D-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. (564 aa) |
| | bioD | ATP-dependent dethiobiotin synthetase BioD 1; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (239 aa) |
| | alaS | Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (875 aa) |
| | AHG84075.1 | Pyruvate dehydrogenase dihydrolipoyltransacetylase PRK11854; Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex of Pasteurellaceae UniRef RepID=ODP2_HAEIN. (104 aa) |
| | AHG84074.1 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (529 aa) |
| | aceE | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (887 aa) |
| | AHG84072.1 | Asparaginase of Lactobacillales UniRef RepID=Q03PH2_LACBA. (321 aa) |
| | ispD | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (231 aa) |
| | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (158 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (360 aa) |
| | F543_1200 | Beta-lactamase fold protein; Predicted Zn-dependent hydrolases of the beta-lactamase fold COG2220; Beta-lactamase fold protein of Neisseriaceae UniRef RepID=C5TP76_NEIFL. (303 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (365 aa) |
| | AHG84046.1 | Methionine synthase; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase PRK09121; Methionine synthase (B12-independent) of Bacteria UniRef RepID=Q07X59_SHEFN. (343 aa) |
| | serS | Seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (434 aa) |
| | asnS | asparaginyl-tRNA synthetase PRK03932; Asparaginyl-tRNA synthetase of Bacteria UniRef RepID=SYN_HAEIN. (467 aa) |
| | F543_1150 | 4-hydroxybenzoate synthetase (Chorismate lyase); Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. (166 aa) |
| | AHG84007.1 | Bifunctional malic enzyme oxidoreductase/phosphotransacetylase PRK07232; NADP-dependent malic enzyme of Bacteria UniRef RepID=MAO2_SALTY. (757 aa) |
| | AHG84006.1 | Acetolactate synthase 3 catalytic subunit PRK06882; Acetolactate synthase isozyme 3 large subunit of Proteobacteria UniRef RepID=ILVI_ECOLI. (573 aa) |
| | ilvN | Acetolactate synthase 3 regulatory subunit PRK11895; Acetolactate synthase small subunit of root UniRef RepID=ILVH_HAEIN. (163 aa) |
| | cysS | cysteinyl-tRNA synthetase PRK00260; Cysteinyl-tRNA synthetase of Gammaproteobacteria UniRef RepID=E0WSA9_9ENTR; Belongs to the class-I aminoacyl-tRNA synthetase family. (461 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (272 aa) |
| | glnS | glutaminyl-tRNA synthetase PRK05347; Glutaminyl-tRNA synthetase of Bacteria UniRef RepID=SYQ_PECCP. (557 aa) |
| | guaA | GMP synthase; Catalyzes the synthesis of GMP from XMP. (522 aa) |
| | AHG83965.1 | Phosphoglycerate mutase of Pasteurellaceae UniRef RepID=B0BSN7_ACTPJ. (208 aa) |
| | glyA | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (421 aa) |
| | argF | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (341 aa) |
| | AHG83956.1 | Aromatic amino acid aminotransferase PRK09257; Aspartate aminotransferase of Proteobacteria UniRef RepID=AAT_HAEIN. (398 aa) |
| | AHG83943.1 | Cystathionine gamma-synthase PRK08247; Cystathionine gamma-synthase of Bacteria UniRef RepID=METB_HAEIN. (372 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (270 aa) |
| | AHG83917.1 | Isocitrate dehydrogenase PRK07006; Isocitrate dehydrogenase [NADP] of Gammaproteobacteria UniRef RepID=B7UV18_PSEA8. (415 aa) |
| | citD | Citrate lyase acyl carrier protein; Covalent carrier of the coenzyme of citrate lyase. (95 aa) |
| | AHG83908.1 | Sulfite reductase, alpha subunit (flavoprotein) COG0369; Possible sulfite reductase (NADPH) alpha subunit of Pasteurellaceae UniRef RepID=A7JU49_PASHA. (517 aa) |
| | AHG83907.1 | 5,10-methylenetetrahydrofolate reductase PRK09432; 5,10-methylenetetrahydrofolate reductase of Proteobacteria UniRef RepID=METF_PECCC; Belongs to the methylenetetrahydrofolate reductase family. (294 aa) |
| | AHG83900.1 | Uncharacterized conserved protein COG1556; uncharacterized protein of Gallibacterium anatis UMN179 UniRef RepID=F4HCX8_GALAU. (234 aa) |
| | AHG83899.1 | Lactate utilization protein B of Firmicutes UniRef RepID=LUTB_BACLD. (469 aa) |
| | AHG83896.1 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (144 aa) |
| | murQ | N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. (305 aa) |
| | anmK | Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (371 aa) |
| | odhB | Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (408 aa) |
| | fumC | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (877 aa) |
| | lipA | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (314 aa) |
| | selD | Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. (294 aa) |
| | F543_9660 | Dihydroneopterin triphosphate pyrophosphatase PRK09438; Dihydroneopterin triphosphate pyrophosphatase of Gammaproteobacteria UniRef RepID=NUDB_HAEIN. (145 aa) |
| | F543_9470 | Cystathionine beta-lyase PRK08114; Cystathionine beta-lyase of Proteobacteria UniRef RepID=METC_HAEIN. (152 aa) |
| | F543_9460 | Cystathionine beta-lyase PRK08114; Cystathionine beta-lyase of Proteobacteria UniRef RepID=METC_HAEIN. (235 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (493 aa) |
| | F543_9320 | MHT1 protein; Homocysteine/selenocysteine methylase (S-methylmethionine-dependent) COG2040; MHT1 protein of Pasteurellaceae UniRef RepID=Q65V50_MANSM. (304 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (396 aa) |
| | fadD | long-chain-fatty-acid--CoA ligase PRK08974; Long-chain-fatty-acid--CoA ligase of root UniRef RepID=LCFA_HAEIN. (561 aa) |
| | yciA | acyl-CoA thioester hydrolase; acyl-CoA esterase PRK10694; Uncharacterized acyl-CoA thioester hydrolase HI_0827 of Proteobacteria UniRef RepID=Y827_HAEIN. (130 aa) |
| | F543_8920 | T-protein; Bifunctional chorismate mutase/prephenate dehydrogenase PRK11199; T-protein of Bacteria UniRef RepID=TYRA_HAEIN. (374 aa) |
| | F543_8910 | Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (354 aa) |
| | fabZ | (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (155 aa) |
| | gloB | Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (212 aa) |
| | argG | Argininosuccinate synthase PRK05370; Argininosuccinate synthase of root UniRef RepID=Q46QJ6_CUPPJ; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (443 aa) |
| | aspA | Aspartate ammonia-lyase PRK12273; Aspartate ammonia-lyase of Bacteria UniRef RepID=ASPA_HAEIN. (474 aa) |
| | folK | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase of Gammaproteobacteria UniRef RepID=HPPK_HAEIN. (157 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (441 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (334 aa) |
| | F543_8260 | Anthranilate synthase component I PRK13564; Anthranilate synthase component I of Haemophilus influenzae HK1212 UniRef RepID=D1NHI9_HAEIF. (50 aa) |
| | trpE | Anthranilate synthase component I PRK13564; Anthranilate synthase component I of Gammaproteobacteria UniRef RepID=Q47YC4_COLP3. (454 aa) |
| | F543_8080 | Bifunctional aspartokinase I/homoserine dehydrogenase I PRK09436; Bifunctional aspartokinase/homoserine dehydrogenase of Bacteria UniRef RepID=AKH_HAEIN; In the C-terminal section; belongs to the homoserine dehydrogenase family. (832 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (213 aa) |
| | F543_8060 | Homoserine kinase PRK01212; Homoserine kinase of Pasteurellaceae UniRef RepID=A4P0B7_HAEIF. (99 aa) |
| | pyk | Pyruvate kinase PRK05826; Pyruvate kinase of root UniRef RepID=KPYK_HAEIN; Belongs to the pyruvate kinase family. (466 aa) |
| | F543_7830 | Branched-chain amino acid aminotransferase PRK13357; Branched-chain-amino-acid aminotransferase of cellular organisms UniRef RepID=ILVE_HAEIN. (340 aa) |
| | thrS | Threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (652 aa) |
| | leuS | leucyl-tRNA synthetase PRK00390; Leucyl-tRNA synthetase of Proteobacteria UniRef RepID=SYL_SALDC; Belongs to the class-I aminoacyl-tRNA synthetase family. (863 aa) |
| | F543_730 | Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases COG0365; acyl-coenzyme A synthetase-related protein of Histophilus somni UniRef RepID=Q0I109_HAES1. (401 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (515 aa) |
| | F543_710 | AMP-binding enzyme; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II COG0318; AMP-binding enzyme of Pasteurellaceae UniRef RepID=C6AQC2_AGGAN. (510 aa) |
| | F543_700 | Acyl carrier protein PRK05350; uncharacterized protein of Neisseriaceae UniRef RepID=C0DY74_EIKCO. (81 aa) |
| | kdsA | 2-dehydro-3-deoxyphosphooctonate aldolase PRK05198; 2-dehydro-3-deoxyphosphooctonate aldolase of cellular organisms UniRef RepID=KDSA_SHEDO; Belongs to the KdsA family. (284 aa) |
| | F543_690 | Acyl carrier protein PRK09184; Acyl carrier protein of Bacteria UniRef RepID=Q5E6K5_VIBF1. (86 aa) |
| | F543_6860 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1237 aa) |
| | F543_670 | Uncharacterized protein of Pasteurellaceae UniRef RepID=B0URR9_HAES2. (234 aa) |
| | F543_650 | 3-oxoacyl-(acyl carrier protein) synthase II PRK09116; Beta-ketoacyl synthase of cellular organisms UniRef RepID=A6WI56_SHEB8; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (413 aa) |
| | fabG-2 | Reductase; 3-ketoacyl-(acyl-carrier-protein) reductase PRK05653; 3-oxoacyl-[acyl-carrier-protein] reductase FabG of Bacteria UniRef RepID=FABG_AGGAC. (242 aa) |
| | F543_620 | 3-oxoacyl-(acyl carrier protein) synthase I PRK09185; 3-oxoacyl-[acyl-carrier-protein] synthase (Beta-ketoacyl-ACP synthase) of Proteobacteria UniRef RepID=Q0I119_HAES1; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (405 aa) |
| | gltX | Glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (479 aa) |
| | F543_5480 | Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase of Pasteurellaceae UniRef RepID=B0BQ85_ACTPJ. (200 aa) |
| | aroE | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (272 aa) |
| | pgi | Glucose-6-phosphate isomerase PRK00179; Glucose-6-phosphate isomerase of root UniRef RepID=G6PI_HUMAN; Belongs to the GPI family. (546 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (362 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (161 aa) |
| | grcA | Autonomous glycyl radical cofactor; Acts as a radical domain for damaged PFL and possibly other radical proteins. (127 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (416 aa) |
| | bioB | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (348 aa) |
| | serB | SerB protein; Phosphoserine phosphatase PRK11133; SerB protein of Pasteurellaceae UniRef RepID=Q65RP5_MANSM. (288 aa) |
| | F543_4600 | Threonine synthase PRK09225; Threonine synthase of Bacteria UniRef RepID=THRC_BUCBP. (427 aa) |
| | F543_4490 | Aspartate-semialdehyde dehydrogenase PRK06901; Aspartate-semialdehyde dehydrogenase of Pasteurellaceae UniRef RepID=B8F3D8_HAEPS. (328 aa) |
| | ilvA | Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (536 aa) |
| | F543_4200 | DNA-binding transcriptional regulator MetR PRK15421; Transcriptional regulator of Proteobacteria UniRef RepID=Q0I492_HAES1; Belongs to the LysR transcriptional regulatory family. (308 aa) |
| | mtnN | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (230 aa) |
| | nanE | N-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (229 aa) |
| | F543_4150 | N-acetylmannosamine kinase PRK05082; N-acetylmannosamine kinase of Gammaproteobacteria UniRef RepID=NANK_HAEIE. (281 aa) |
| | metJ | Met repressor; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. (105 aa) |
| | fabH | 3-oxoacyl-[acyl-carrier-protein] synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (305 aa) |
| | F543_4010 | 3-oxoacyl-(acyl carrier protein) synthase I PRK07967; 3-oxoacyl-[acyl-carrier-protein] synthase 1 of cellular organisms UniRef RepID=FABB_ECOL6; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (405 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (371 aa) |
| | F543_3700 | Hypothetical protein; L-cysteine desulfidase COG3681; UPF0597 protein YE0448 of Bacteria UniRef RepID=Y448_YERE8; Belongs to the UPF0597 family. (431 aa) |
| | carA | Carbamoyl phosphate synthase small subunit PRK12564; Carbamoyl-phosphate synthase small chain of root UniRef RepID=CARA_POLSQ; Belongs to the CarA family. (379 aa) |
| | carB | Carbamoyl phosphate synthase large subunit PRK05294; Carbamoyl-phosphate synthase large chain of cellular organisms UniRef RepID=CARB_HAEDU; Belongs to the CarB family. (1067 aa) |
| | glmS | Glucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (610 aa) |
| | nagB | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (264 aa) |
| | F543_3330 | Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (220 aa) |
| | coaBC | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (403 aa) |
