STRINGSTRING
fumC fumC odhB odhB sucA sucA AHG83917.1 AHG83917.1 acnB acnB AHG83919.1 AHG83919.1 pckA pckA aceE aceE AHG84074.1 AHG84074.1 AHG84076.1 AHG84076.1 lpdA lpdA mdh mdh sucD sucD sucC sucC AHG84897.1 AHG84897.1 AHG84898.1 AHG84898.1 frdC frdC frdD frdD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa)
odhBDihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (408 aa)
sucA2-oxoglutarate dehydrogenase E1 component PRK09404; 2-oxoglutarate dehydrogenase E1 component of Gammaproteobacteria UniRef RepID=ODO1_HAEIN. (935 aa)
AHG83917.1Isocitrate dehydrogenase PRK07006; Isocitrate dehydrogenase [NADP] of Gammaproteobacteria UniRef RepID=B7UV18_PSEA8. (415 aa)
acnBBifunctional aconitate hydratase 2/2-methylisocitrate dehydratase PRK09238; Aconitate hydratase 2 of cellular organisms UniRef RepID=ACON2_PSEAE; Belongs to the aconitase/IPM isomerase family. (867 aa)
AHG83919.1Type II citrate synthase PRK05614; Citrate synthase I of Bacteria UniRef RepID=E3I1M6_RHOVT; Belongs to the citrate synthase family. (426 aa)
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (536 aa)
aceEPyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (887 aa)
AHG84074.1Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (529 aa)
AHG84076.1Dihydrolipoamide dehydrogenase PRK06467; Dihydrolipoyl dehydrogenase of cellular organisms UniRef RepID=DLDH_HAEIN; overlaps CDS with the same product name. (263 aa)
lpdADihydrolipoamide dehydrogenase PRK06467; Dihydrolipoyl dehydrogenase of cellular organisms UniRef RepID=DLDH_HAEIN; overlaps CDS with the same product name. (241 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (314 aa)
sucDSuccinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (289 aa)
sucCSuccinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa)
AHG84897.1Fumarate reductase flavoprotein subunit PRK09231; Fumarate reductase flavoprotein subunit of cellular organisms UniRef RepID=FRDA_HAEIN. (596 aa)
AHG84898.1Fumarate reductase iron-sulfur subunit PRK12385; Fumarate reductase iron-sulfur subunit of Proteobacteria UniRef RepID=FRDB_HAEIN; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (255 aa)
frdCReductase; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (129 aa)
frdDReductase; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (114 aa)
Your Current Organism:
Bibersteinia trehalosi
NCBI taxonomy Id: 1263831
Other names: B. trehalosi USDA-ARS-USMARC-189, Bibersteinia trehalosi USDA-ARS-USMARC-189
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.