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| | fumC | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa) |
| | odhB | Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (408 aa) |
| | sucA | 2-oxoglutarate dehydrogenase E1 component PRK09404; 2-oxoglutarate dehydrogenase E1 component of Gammaproteobacteria UniRef RepID=ODO1_HAEIN. (935 aa) |
| | AHG83880.1 | L-serine dehydratase TdcG PRK15040; L-serine dehydratase of root UniRef RepID=SDHL_HAEIN; Belongs to the iron-sulfur dependent L-serine dehydratase family. (459 aa) |
| | AHG83917.1 | Isocitrate dehydrogenase PRK07006; Isocitrate dehydrogenase [NADP] of Gammaproteobacteria UniRef RepID=B7UV18_PSEA8. (415 aa) |
| | acnB | Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase PRK09238; Aconitate hydratase 2 of cellular organisms UniRef RepID=ACON2_PSEAE; Belongs to the aconitase/IPM isomerase family. (867 aa) |
| | AHG83919.1 | Type II citrate synthase PRK05614; Citrate synthase I of Bacteria UniRef RepID=E3I1M6_RHOVT; Belongs to the citrate synthase family. (426 aa) |
| | AHG83936.1 | Phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (837 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (270 aa) |
| | AHG83943.1 | Cystathionine gamma-synthase PRK08247; Cystathionine gamma-synthase of Bacteria UniRef RepID=METB_HAEIN. (372 aa) |
| | AHG83951.1 | Protein UshA; Bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor PRK09558; Protein UshA of Proteobacteria UniRef RepID=USHA_YERE8; Belongs to the 5'-nucleotidase family. (549 aa) |
| | AHG83952.1 | Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (120 aa) |
| | AHG83956.1 | Aromatic amino acid aminotransferase PRK09257; Aspartate aminotransferase of Proteobacteria UniRef RepID=AAT_HAEIN. (398 aa) |
| | argF | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (341 aa) |
| | glyA | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (421 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (487 aa) |
| | glgA | Glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (503 aa) |
| | glgC | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (426 aa) |
| | glgB | 1,4-alpha-glucan branching enzyme GlgB; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (763 aa) |
| | glpX | Fructose-1,6-bisphosphatase class 2; Fructose 1,6-bisphosphatase II PRK09479; Fructose-1,6-bisphosphatase class 2 of Bacteria UniRef RepID=GLPX_HAEIN. (339 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (272 aa) |
| | ilvN | Acetolactate synthase 3 regulatory subunit PRK11895; Acetolactate synthase small subunit of root UniRef RepID=ILVH_HAEIN. (163 aa) |
| | AHG84006.1 | Acetolactate synthase 3 catalytic subunit PRK06882; Acetolactate synthase isozyme 3 large subunit of Proteobacteria UniRef RepID=ILVI_ECOLI. (573 aa) |
| | F543_1150 | 4-hydroxybenzoate synthetase (Chorismate lyase); Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. (166 aa) |
| | hpt | Hypoxanthine phosphoribosyltransferase PRK15423; Hypoxanthine phosphoribosyltransferase of cellular organisms UniRef RepID=A7FM30_YERP3; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (182 aa) |
| | ubiA | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (294 aa) |
| | AHG84035.1 | Adenylosuccinate lyase PRK09285; Adenylosuccinate lyase of cellular organisms UniRef RepID=PUR8_HAEIN; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (456 aa) |
| | AHG84046.1 | Methionine synthase; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase PRK09121; Methionine synthase (B12-independent) of Bacteria UniRef RepID=Q07X59_SHEFN. (343 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (365 aa) |
| | AHG84061.1 | O-succinylbenzoic acid--CoA ligase PRK09029; O-succinylbenzoic acid--CoA ligase of Actinobacillus minor UniRef RepID=C5S0N7_9PAST. (470 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (360 aa) |
| | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (158 aa) |
| | ispD | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (231 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (536 aa) |
| | AHG84072.1 | Asparaginase of Lactobacillales UniRef RepID=Q03PH2_LACBA. (321 aa) |
| | aceE | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (887 aa) |
| | AHG84074.1 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (529 aa) |
| | AHG84076.1 | Dihydrolipoamide dehydrogenase PRK06467; Dihydrolipoyl dehydrogenase of cellular organisms UniRef RepID=DLDH_HAEIN; overlaps CDS with the same product name. (263 aa) |
| | lpdA | Dihydrolipoamide dehydrogenase PRK06467; Dihydrolipoyl dehydrogenase of cellular organisms UniRef RepID=DLDH_HAEIN; overlaps CDS with the same product name. (241 aa) |
| | galU | UTP--glucose-1-phosphate uridylyltransferase subunit GalU PRK13389; UTP--glucose-1-phosphate uridylyltransferase of root UniRef RepID=GALU_HAEIN. (295 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (431 aa) |
| | hisC | Histidinol-phosphate aminotransferase PRK02731; Histidinol-phosphate aminotransferase 1 of Proteobacteria UniRef RepID=HIS81_MANSM; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (365 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase PRK09362; Phosphoribosylaminoimidazole-succinocarboxamide synthase of Bacteria UniRef RepID=PUR7_EXIS2; Belongs to the SAICAR synthetase family. (236 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (405 aa) |
| | purM | Phosphoribosylaminoimidazole synthetase PRK05385; Phosphoribosylformylglycinamidine cyclo-ligase of Bacteria UniRef RepID=PUR5_BIFA0. (339 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (188 aa) |
| | purH | Bifunctional purine biosynthesis protein PurH; Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PRK00881; Bifunctional purine biosynthesis protein PurH of Bacteria UniRef RepID=PUR9_ENTFA. (532 aa) |
| | purD | Phosphoribosylamine--glycine ligase PRK00885; Phosphoribosylamine--glycine ligase of Bacteria UniRef RepID=PUR2_BACHD; Belongs to the GARS family. (419 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (164 aa) |
| | purK | 5-(Carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (260 aa) |
| | serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (287 aa) |
| | lysC | Aspartate kinase III PRK09084; Lysine-sensitive aspartokinase 3 of Bacteria UniRef RepID=AK3_ECOLI; Belongs to the aspartokinase family. (450 aa) |
| | AHG84119.1 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (357 aa) |
| | AHG84126.1 | Reductase; Enoyl-(acyl carrier protein) reductase PRK07984; Enoyl-[acyl-carrier-protein] reductase [NADH] FabI of root UniRef RepID=FABI_HAEIN. (260 aa) |
| | menH | Hydrolase; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). (252 aa) |
| | menD | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. (569 aa) |
| | hemL | Glutamate-1-semialdehyde aminotransferase PRK00062; Glutamate-1-semialdehyde 2,1-aminomutase of root UniRef RepID=GSA_BURM7. (427 aa) |
| | ubiG | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. (240 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (367 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (298 aa) |
| | accD | Acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (298 aa) |
| | F543_1360 | 1-acyl-sn-glycerol-3-phosphate acyltransferase PRK15018; 1-acyl-sn-glycerol-3-phosphate acyltransferase of Gammaproteobacteria UniRef RepID=B0BR80_ACTPJ; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (240 aa) |
| | ispE | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (280 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (316 aa) |
| | accA | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa) |
| | AHG84270.1 | Multifunctional fatty acid oxidation complex subunit alpha PRK11154; Fatty oxidation complex, alpha subunit of Haemophilus parasuis UniRef RepID=B8F4S2_HAEPS; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (714 aa) |
| | AHG84271.1 | 3-ketoacyl-CoA thiolase PRK08963; Acetyl-CoA acetyltransferase of Pasteurellaceae UniRef RepID=B0BPH2_ACTPJ; Belongs to the thiolase-like superfamily. Thiolase family. (434 aa) |
| | AHG84297.1 | FAD-dependent monooxygenase; 2-octaprenyl-6-methoxyphenol hydroxylase PRK08850; FAD-dependent monooxygenase of Haemophilus parasuis UniRef RepID=B8F390_HAEPS. (394 aa) |
| | metXA | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (362 aa) |
| | gpmA | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (227 aa) |
| | trpA | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (270 aa) |
| | trpB | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (390 aa) |
| | leuC | 3-isopropylmalate dehydratase large subunit-like protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (468 aa) |
| | leuD | 3-isopropylmalate dehydratase large subunit-like protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (219 aa) |
| | F543_1470 | Protoporphyrinogen oxidase PRK11104; Protoporphyrinogen oxidase of Pasteurellaceae UniRef RepID=B8F801_HAEPS. (172 aa) |
| | ubiE | Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (250 aa) |
| | trpF | Tryptophan biosynthesis protein TrpCF; Bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase PRK09427; Tryptophan biosynthesis protein TrpCF of Gammaproteobacteria UniRef RepID=TRPC_HAEIN. (471 aa) |
| | AHG84363.1 | Acyltransferase PRK05790; Acetyl-CoA acetyltransferase of cellular organisms UniRef RepID=THIL_CUPNH; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa) |
| | menC | O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (323 aa) |
| | AHG84387.1 | Uncharacterized enzyme of heme biosynthesis COG2959; Uroporphyrin-III C-methyltransferase of Pasteurellaceae UniRef RepID=E0FMY7_ACTPL. (464 aa) |
| | AHG84388.1 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (252 aa) |
| | hemC | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (307 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (321 aa) |
| | gpt | Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (159 aa) |
| | AHG84470.1 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (359 aa) |
| | pgk | Phosphoglycerate kinase PRK00073; Phosphoglycerate kinase of Aggregatibacter actinomycetemcomitans UniRef RepID=G4ACN5_AGGAC; Belongs to the phosphoglycerate kinase family. (385 aa) |
| | ispG | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (369 aa) |
| | AHG84519.1 | Inositol-1-monophosphatase; Inositol monophosphatase PRK10757; Inositol-1-monophosphatase of Bacteria UniRef RepID=SUHB_PASMU. (269 aa) |
| | dxs | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (639 aa) |
| | glpE | Thiosulfate sulfurtransferase glpE; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide. (108 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. (314 aa) |
| | argJ | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (406 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (290 aa) |
| | argD | Acetylornithine aminotransferase PRK02627; Acetylornithine aminotransferase of Haemophilus ducreyi 35000HP UniRef RepID=ARGD_HAEDU; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (393 aa) |
| | iolG | Inositol 2-dehydrogenase; Predicted dehydrogenases and proteins COG0673; Inositol 2-dehydrogenase of Mitsuokella multacida DSM 20544 UniRef RepID=C9KMM7_9FIRM. (336 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (314 aa) |
| | menF | Menaquinone-specific isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. (422 aa) |
| | AHG84608.1 | Aminotransferase AlaT PRK09265; Aminotransferase AlaT of Bacteria UniRef RepID=B8F699_HAEPS. (405 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (214 aa) |
| | pheA | Bifunctional chorismate mutase/prephenate dehydratase PRK10622; Bifunctional prephenate dehydratase/chorismate mutase of Gammaproteobacteria UniRef RepID=B8F6C2_HAEPS. (385 aa) |
| | sucD | Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (289 aa) |
| | sucC | Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa) |
| | AHG84630.1 | Bifunctional acetaldehyde-CoA/alcohol dehydrogenase PRK13805; Iron-containing alcohol dehydrogenase of Bacteria UniRef RepID=C7QZE3_JONDD; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (896 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (495 aa) |
| | pgl | Hypothetical protein; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (236 aa) |
| | gnd | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (484 aa) |
| | argH | Argininosuccinate lyase PRK04833; Argininosuccinate lyase of cellular organisms UniRef RepID=ARLY_TOLAT. (472 aa) |
| | AHG84660.1 | Phosphatidylserine synthase PRK09428; CDP-diacylglycerol--serine O-phosphatidyltransferase of Gammaproteobacteria UniRef RepID=PSS_HAEIN. (415 aa) |
| | AHG84662.1 | Riboflavin biosynthesis protein; Bifunctional riboflavin kinase/FMN adenylyltransferase PRK05627; Riboflavin biosynthesis protein of Actinobacillus UniRef RepID=B0BRK4_ACTPJ; Belongs to the ribF family. (314 aa) |
| | metE | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (756 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (142 aa) |
| | ilvD | Dihydroxy-acid dehydratase PRK12448; Dihydroxy-acid dehydratase of Bacteria UniRef RepID=D8IY91_HERSS; Belongs to the IlvD/Edd family. (597 aa) |
| | AHG84706.1 | 4-alpha-glucanotransferase PRK11052; 4-alpha-glucanotransferase of Pasteurellaceae UniRef RepID=C6ANA8_AGGAN. (695 aa) |
| | glgP | Maltodextrin phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (789 aa) |
| | AHG84709.1 | Alpha-amylase PRK09505; Alpha-amylase of Gammaproteobacteria UniRef RepID=AMY1_ECOLI. (718 aa) |
| | fbp | Fructose-1,6-bisphosphatase PRK09293; Fructose-1,6-bisphosphatase class 1 of Bacteria UniRef RepID=F16PA_PROMH; Belongs to the FBPase class 1 family. (333 aa) |
| | AHG84725.1 | Serine acetyltransferase PRK11132; Serine acetyltransferase of cellular organisms UniRef RepID=B4F141_PROMH; overlaps CDS with the same product name. (233 aa) |
| | gpsA | NAD(P)H-dependent glycerol-3-phosphate dehydrogenase PRK00094; Glycerol-3-phosphate dehydrogenase [NAD(P)+] of cellular organisms UniRef RepID=GPDA_PHOLL; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (340 aa) |
| | hisI | Histidine biosynthesis bifunctional protein HisIE; Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein PRK02759; Histidine biosynthesis bifunctional protein HisIE of Bacteria UniRef RepID=HIS2_HAEIN; In the N-terminal section; belongs to the PRA-CH family. (212 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (257 aa) |
| | hisA | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase PRK00748; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase of Bacteria UniRef RepID=HIS4_ACTP2. (249 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (197 aa) |
| | hisB | Histidine biosynthesis bifunctional protein hisB; Imidazole glycerol-phosphate dehydratase/histidinol phosphatase PRK05446; Histidine biosynthesis bifunctional protein hisB of Bacteria UniRef RepID=HIS7_ACTSZ; In the N-terminal section; belongs to the histidinol- phosphatase family. (362 aa) |
| | hisC-2 | Histidinol-phosphate aminotransferase PRK01688; Histidinol-phosphate aminotransferase of Bacteria UniRef RepID=HIS8_YERE8; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (353 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (432 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (298 aa) |
| | accC | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa) |
| | AHG84788.1 | Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (155 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (146 aa) |
| | plsX | Phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (188 aa) |
| | cysK | Cysteine synthase A PRK10717; Cysteine synthase of Bacteria UniRef RepID=Q482P1_COLP3; Belongs to the cysteine synthase/cystathionine beta- synthase family. (316 aa) |
| | fabG | 3-ketoacyl-(Acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (242 aa) |
| | fabD | Malonyl CoA-acyl carrier protein transacylase of root UniRef RepID=FABD_HAEIN. (311 aa) |
| | AHG84857.1 | Octaprenyl diphosphate synthase PRK10888; Octaprenyl-diphosphate synthase of root UniRef RepID=ISPB_HAEIN; Belongs to the FPP/GGPP synthase family. (327 aa) |
| | rpiA | Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (230 aa) |
| | AHG84862.1 | D-3-phosphoglycerate dehydrogenase PRK11790; D-3-phosphoglycerate dehydrogenase of Bacteria UniRef RepID=SERA_HAEIN; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (409 aa) |
| | tal | Transaldolase 1; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (401 aa) |
| | AHG84897.1 | Fumarate reductase flavoprotein subunit PRK09231; Fumarate reductase flavoprotein subunit of cellular organisms UniRef RepID=FRDA_HAEIN. (596 aa) |
| | AHG84898.1 | Fumarate reductase iron-sulfur subunit PRK12385; Fumarate reductase iron-sulfur subunit of Proteobacteria UniRef RepID=FRDB_HAEIN; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (255 aa) |
| | frdC | Reductase; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (129 aa) |
| | frdD | Reductase; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (114 aa) |
| | asnA | Aspartate--ammonia ligase; Asparagine synthetase AsnA PRK05425; Aspartate--ammonia ligase of cellular organisms UniRef RepID=ASNA_HAEIE. (330 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1320 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (76 aa) |
| | AHG84944.1 | Glycerate kinase of Bacteria UniRef RepID=B0US17_HAES2; Belongs to the glycerate kinase type-1 family. (378 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (414 aa) |
| | AHG85000.1 | D-isomer specific 2-hydroxyacid dehydrogenase family protein of Proteobacteria UniRef RepID=Q4KE06_PSEF5. (352 aa) |
| | miaA | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (313 aa) |
| | AHG85032.1 | 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase PRK08020; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase of Gallibacterium anatis UMN179 UniRef RepID=F4HCD6_GALAU. (393 aa) |
| | plsY | Glycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (207 aa) |
| | AHG85047.1 | Thioesterase PRK10254; Esterase YbdB of Pasteurellaceae UniRef RepID=E8KKP9_9PAST. (139 aa) |
| | ispH | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (314 aa) |
| | AHG85062.1 | Shikimate kinase PRK13946; Carbohydrate kinase, thermoresistant glucokinase family of Gammaproteobacteria UniRef RepID=A6WTN5_SHEB8. (171 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (274 aa) |
| | AHG85098.1 | Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase COG4589; Phosphatidate cytidylyltransferase of root UniRef RepID=B4SL85_STRM5. (307 aa) |
| | putA | 1-pyrroline-5-carboxylate dehydrogenase /proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1198 aa) |
| | menB | 1,4-dihydroxy-2-naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). (285 aa) |
| | hemB | Porphobilinogen synthase; Delta-aminolevulinic acid dehydratase PRK09283; Porphobilinogen synthase of cellular organisms UniRef RepID=A1WVW5_HALHL; Belongs to the ALAD family. (341 aa) |
| | psd | Phosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (296 aa) |
| | surE | 5'-nucleotidase surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (254 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (255 aa) |
| | F543_3150 | L-asparaginase II PRK11096; L-asparaginase of Bacteria UniRef RepID=C6AJK5_AGGAN; Belongs to the asparaginase 1 family. (349 aa) |
| | F543_3270 | Phosphomannomutase of Actinobacillus UniRef RepID=B0BUE9_ACTPJ. (552 aa) |
| | F543_3330 | Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (220 aa) |
| | ubiD | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. (491 aa) |
| | manA | Mannose-6-phosphate isomerase PRK15131; Mannose-6-phosphate isomerase of Pasteurellaceae UniRef RepID=B8F7E6_HAEPS. (402 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (371 aa) |
| | F543_3850 | Fructokinase; Aminoimidazole riboside kinase PRK09434; Fructokinase of Gammaproteobacteria UniRef RepID=SCRK_VIBAL; Belongs to the carbohydrate kinase PfkB family. (307 aa) |
| | F543_3860 | SacC protein; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family. (476 aa) |
| | F543_3900 | dTDP-glucose 4,6-dehydratase 2; dTDP-glucose 4,6 dehydratase PRK10084; dTDP-glucose 4,6-dehydratase 2 of Bacteria UniRef RepID=RMLB2_ECOLI; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (353 aa) |
| | rfbA | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (292 aa) |
| | rfbD | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (294 aa) |
| | rfbC | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (179 aa) |
| | hemH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (319 aa) |
| | deoD | Purine nucleoside phosphorylase PRK05819; Purine nucleoside phosphorylase deoD-type of cellular organisms UniRef RepID=DEOD_ECO24. (238 aa) |
| | ilvA | Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (536 aa) |
| | menA | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (315 aa) |
| | katG | Catalase-peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (722 aa) |
| | F543_4600 | Threonine synthase PRK09225; Threonine synthase of Bacteria UniRef RepID=THRC_BUCBP. (427 aa) |
| | serB | SerB protein; Phosphoserine phosphatase PRK11133; SerB protein of Pasteurellaceae UniRef RepID=Q65RP5_MANSM. (288 aa) |
| | ribH | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. (153 aa) |
| | ribBA | Riboflavin biosynthesis bifunctional protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (401 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (416 aa) |
| | F543_4800 | Riboflavin synthase subunit alpha PRK09289; Riboflavin synthase alpha chain of cellular organisms UniRef RepID=RISA_ACTPL. (214 aa) |
| | ribD | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (362 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (161 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (362 aa) |
| | pgi | Glucose-6-phosphate isomerase PRK00179; Glucose-6-phosphate isomerase of root UniRef RepID=G6PI_HUMAN; Belongs to the GPI family. (546 aa) |
| | aroE | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (272 aa) |
| | gltX | Glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (479 aa) |
| | glpC | Sn-glycerol-3-phosphate dehydrogenase subunit C PRK11168; Anaerobic glycerol-3-phosphate dehydrogenase subunit C of Gammaproteobacteria UniRef RepID=GLPC_HAEIN. (425 aa) |
| | glpB | Anaerobic glycerol-3-phosphate dehydrogenase subunit B; Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor. (424 aa) |
| | F543_6200 | Sn-glycerol-3-phosphate dehydrogenase subunit A PRK11101; Anaerobic glycerol-3-phosphate dehydrogenase subunit A of Bacteria UniRef RepID=GLPA_HAEIN; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (563 aa) |
| | F543_6230 | Ribulose-phosphate 3-epimerase PRK08883; Ribulose-phosphate 3-epimerase of cellular organisms UniRef RepID=C3LRT6_VIBCM; Belongs to the ribulose-phosphate 3-epimerase family. (226 aa) |
| | fabG-2 | Reductase; 3-ketoacyl-(acyl-carrier-protein) reductase PRK05653; 3-oxoacyl-[acyl-carrier-protein] reductase FabG of Bacteria UniRef RepID=FABG_AGGAC. (242 aa) |
| | F543_6530 | 4-alpha-glucanotransferase PRK11052; 4-alpha-glucanotransferase of Pasteurellaceae UniRef RepID=C6ANA8_AGGAN. (654 aa) |
| | F543_6860 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1237 aa) |
| | F543_6870 | Aldose 1-epimerase of Gallibacterium anatis UMN179 UniRef RepID=F4HFN9_GALAU; Belongs to the glucose-6-phosphate 1-epimerase family. (266 aa) |
| | hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (354 aa) |
| | F543_690 | Acyl carrier protein PRK09184; Acyl carrier protein of Bacteria UniRef RepID=Q5E6K5_VIBF1. (86 aa) |
| | F543_6950 | Glycerate dehydrogenase PRK06932; 2-hydroxyacid dehydrogenase HI_1556 of cellular organisms UniRef RepID=Y1556_HAEIN; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (315 aa) |
| | F543_700 | Acyl carrier protein PRK05350; uncharacterized protein of Neisseriaceae UniRef RepID=C0DY74_EIKCO. (81 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (515 aa) |
| | F543_7830 | Branched-chain amino acid aminotransferase PRK13357; Branched-chain-amino-acid aminotransferase of cellular organisms UniRef RepID=ILVE_HAEIN. (340 aa) |
| | F543_7850 | dUMP phosphatase PRK09449; Possible HAD superfamily haloacid dehalogenase hydrolase of Pasteurellaceae UniRef RepID=A7JX35_PASHA. (226 aa) |
| | pyk | Pyruvate kinase PRK05826; Pyruvate kinase of root UniRef RepID=KPYK_HAEIN; Belongs to the pyruvate kinase family. (466 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (213 aa) |
| | F543_8080 | Bifunctional aspartokinase I/homoserine dehydrogenase I PRK09436; Bifunctional aspartokinase/homoserine dehydrogenase of Bacteria UniRef RepID=AKH_HAEIN; In the C-terminal section; belongs to the homoserine dehydrogenase family. (832 aa) |
| | tkt | Transketolase 2; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (665 aa) |
| | trpE | Anthranilate synthase component I PRK13564; Anthranilate synthase component I of Gammaproteobacteria UniRef RepID=Q47YC4_COLP3. (454 aa) |
| | F543_8270 | Anthranilate synthase component II PRK05670; Anthranilate synthase component II of Gammaproteobacteria UniRef RepID=TRPG_VIBPA. (196 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (334 aa) |
| | plsB | Glycerol-3-phosphate acyltransferase PRK04974; Glycerol-3-phosphate acyltransferase of Gammaproteobacteria UniRef RepID=PLSB_HAEI8; Belongs to the GPAT/DAPAT family. (814 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (441 aa) |
| | argG | Argininosuccinate synthase PRK05370; Argininosuccinate synthase of root UniRef RepID=Q46QJ6_CUPPJ; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (443 aa) |
| | uppS | Undecaprenyl pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. (237 aa) |
| | F543_8680 | CDP-diglyceride synthase PRK11624; Phosphatidate cytidylyltransferase of Pasteurellaceae UniRef RepID=B0UUI1_HAES2; Belongs to the CDS family. (289 aa) |
| | F543_8910 | Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (354 aa) |
| | F543_8920 | T-protein; Bifunctional chorismate mutase/prephenate dehydrogenase PRK11199; T-protein of Bacteria UniRef RepID=TYRA_HAEIN. (374 aa) |
| | hemN | Coproporphyrinogen III oxidase PRK09249; Oxygen-independent coproporphyrinogen-III oxidase of Gammaproteobacteria UniRef RepID=HEMN_SALTI; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (455 aa) |
| | hemA | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (437 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (396 aa) |
| | metK | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (410 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (493 aa) |
| | F543_9460 | Cystathionine beta-lyase PRK08114; Cystathionine beta-lyase of Proteobacteria UniRef RepID=METC_HAEIN. (235 aa) |
| | F543_9690 | UbiH protein; 2-octaprenyl-6-methoxyphenyl hydroxylase PRK05732; UbiH protein (2-octaprenyl-6-methoxyphenol) of Pasteurellaceae UniRef RepID=B0BT79_ACTPJ. (397 aa) |
| | ubiX | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (191 aa) |
| | F543_9950 | Glyceraldehyde-3-phosphate dehydrogenase A PRK15425; Glyceraldehyde-3-phosphate dehydrogenase of root UniRef RepID=G3P_CRYNB; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (339 aa) |
| | F543_9960 | Geranyltranstransferase PRK10581; Farnesyl diphosphate synthase of Bacteria UniRef RepID=ISPA_HAEIN; Belongs to the FPP/GGPP synthase family. (297 aa) |
