STRINGSTRING
ANP39216.1 ANP39216.1 ANP39285.1 ANP39285.1 ANP39440.1 ANP39440.1 ANP39441.1 ANP39441.1 ANP39444.1 ANP39444.1 ANP39457.1 ANP39457.1 edd edd zwf zwf pgi pgi ANP39482.1 ANP39482.1 ANP39483.1 ANP39483.1 ANP39484.1 ANP39484.1 gapA gapA ANP39558.1 ANP39558.1 ANP39587.1 ANP39587.1 ANP39592.1 ANP39592.1 ANP39728.1 ANP39728.1 glpX glpX ANP39754.1 ANP39754.1 prs prs ANP39866.1 ANP39866.1 ANP39951.1 ANP39951.1 ANP39957.1 ANP39957.1 ANP39972.1 ANP39972.1 rpiA rpiA ANP40064.1 ANP40064.1 ANP40071.1 ANP40071.1 ANP40075.1 ANP40075.1 glyA glyA ANP40249.1 ANP40249.1 ANP40267.1 ANP40267.1 ANP40268.1 ANP40268.1 ANP40312.1 ANP40312.1 ANP40313.1 ANP40313.1 acsA acsA fumC fumC ANP40388.1 ANP40388.1 ANP40450.1 ANP40450.1 pgl pgl ANP40585.1 ANP40585.1 gltA gltA ANP40668.1 ANP40668.1 gapA-2 gapA-2 ANP40674.1 ANP40674.1 ANP40684.1 ANP40684.1 pgk pgk pdhA pdhA ANP40702.1 ANP40702.1 ANP40703.1 ANP40703.1 ANP40704.1 ANP40704.1 ANP40752.1 ANP40752.1 ANP40772.1 ANP40772.1 eno eno tpiA tpiA ANP41026.1 ANP41026.1 glcB glcB ANP41184.1 ANP41184.1 ANP41235.1 ANP41235.1 ANP41269.1 ANP41269.1 ANP41279.1 ANP41279.1 ANP41295.1 ANP41295.1 folD folD fhs fhs tal tal gcvP gcvP gcvH gcvH gcvT gcvT ANP41383.1 ANP41383.1 pckA pckA ANP41426.1 ANP41426.1 ANP41500.1 ANP41500.1 accD accD ANP41728.1 ANP41728.1 ANP41767.1 ANP41767.1 ANP41784.1 ANP41784.1 gpmI gpmI ANP41809.1 ANP41809.1 ANP41825.1 ANP41825.1 ANP42014.1 ANP42014.1 ilvA ilvA ANP42150.1 ANP42150.1 ANP42157.1 ANP42157.1 ANP42158.1 ANP42158.1 ANP42159.1 ANP42159.1 ANP42164.1 ANP42164.1 ANP42168.1 ANP42168.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ANP39216.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
ANP39285.13-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA. (291 aa)
ANP39440.13-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (705 aa)
ANP39441.1acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
ANP39444.1Glucokinase; Belongs to the bacterial glucokinase family. (320 aa)
ANP39457.1Keto-deoxy-phosphogluconate aldolase; Catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate. (215 aa)
eddPhosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (603 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (483 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (536 aa)
ANP39482.1Formate dehydrogenase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1003 aa)
ANP39483.1Formate dehydrogenase. (197 aa)
ANP39484.1Formate dehydrogenase subunit gamma. (404 aa)
gapAErythrose-4-phosphate dehydrogenase; Required for glycolysis; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa)
ANP39558.1Isocitrate dehydrogenase; NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate; Belongs to the monomeric-type IDH family. (737 aa)
ANP39587.1Ribose-5-phosphate isomerase. (149 aa)
ANP39592.1Pyruvate, phosphate dikinase. (854 aa)
ANP39728.1Methyltransferase; Belongs to the trimethylamine methyltransferase family. (519 aa)
glpXType II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese. (327 aa)
ANP39754.1Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (476 aa)
prsPhosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (340 aa)
ANP39866.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1146 aa)
ANP39951.1Septum site-determining protein. (405 aa)
ANP39957.1Class I fructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis. (300 aa)
ANP39972.1L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (457 aa)
rpiARibose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (262 aa)
ANP40064.1methylmalonyl-CoA carboxyltransferase. (510 aa)
ANP40071.1acetyl/propionyl-CoA carboxylase subuit alpha. (676 aa)
ANP40075.1methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate. (709 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (431 aa)
ANP40249.1Malate dehydrogenase. (759 aa)
ANP40267.13-hydroxyacyl-CoA dehydrogenase. (733 aa)
ANP40268.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa)
ANP40312.1acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa)
ANP40313.1acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (167 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (652 aa)
fumCClass II fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa)
ANP40388.1Cysteine synthase A; CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis. (344 aa)
ANP40450.1Trimethylamine methyltransferase; Belongs to the trimethylamine methyltransferase family. (514 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (223 aa)
ANP40585.15,10-methylenetetrahydrofolate reductase. (310 aa)
gltACitrate (Si)-synthase; Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Belongs to the citrate synthase family. (431 aa)
ANP40668.1Transketolase; Catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; Belongs to the transketolase family. (673 aa)
gapA-2Erythrose-4-phosphate dehydrogenase; Required for glycolysis; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (333 aa)
ANP40674.1Methylmalonate-semialdehyde dehydrogenase (acylating). (499 aa)
ANP40684.1E3 component of alpha keto acid dehydrogenase complexes LpdC; forms a homodimer; binds one molecule of FAD monomer; catalyzes NAD+-dependent oxidation of dihydrolipoyl cofactors that are covalently linked to the E2 component. (464 aa)
pgkPhosphoglycerate kinase; Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; Belongs to the phosphoglycerate kinase family. (396 aa)
pdhAPyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (337 aa)
ANP40702.1Pyruvate dehydrogenase complex E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (459 aa)
ANP40703.1Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (441 aa)
ANP40704.1Serine acetyltransferase. (268 aa)
ANP40752.1Aconitate hydratase. (929 aa)
ANP40772.1Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (915 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (425 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (246 aa)
ANP41026.1AMP-dependent synthetase. (510 aa)
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (709 aa)
ANP41184.1(R)-hydratase. (147 aa)
ANP41235.1Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. (183 aa)
ANP41269.1S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (370 aa)
ANP41279.1Glyceraldehyde-3-phosphate dehydrogenase; Catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (332 aa)
ANP41295.1Serine acetyltransferase. (260 aa)
folDBifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (300 aa)
fhsFormate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (558 aa)
talFructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (217 aa)
gcvPGlycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (949 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (119 aa)
gcvTGlycine cleavage system protein T; Catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein. (374 aa)
ANP41383.1Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (362 aa)
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (532 aa)
ANP41426.1acyl-CoA dehydrogenase. (565 aa)
ANP41500.1Pyruvate kinase; Belongs to the pyruvate kinase family. (481 aa)
accDacetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (320 aa)
ANP41728.1Serine--glyoxylate aminotransferase. (396 aa)
ANP41767.1Transketolase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (794 aa)
ANP41784.12-dehydro-3-deoxygluconokinase. (308 aa)
gpmIPhosphoglycerate mutase (2,3-diphosphoglycerate-independent); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (506 aa)
ANP41809.1Dihydrolipoyl dehydrogenase. (452 aa)
ANP41825.1acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (368 aa)
ANP42014.1Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate. (751 aa)
ilvAThreonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (408 aa)
ANP42150.1Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine. (317 aa)
ANP42157.1Phosphoserine phosphatase SerB. (291 aa)
ANP42158.1Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (381 aa)
ANP42159.1Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (531 aa)
ANP42164.1acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
ANP42168.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
Your Current Organism:
Epibacterium mobile
NCBI taxonomy Id: 1265309
Other names: E. mobile F1926, Epibacterium mobile F1926, Ruegeria mobilis F1926
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