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ANP39216.1 | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa) | ||||
ANP39285.1 | 3-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA. (291 aa) | ||||
ANP39440.1 | 3-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (705 aa) | ||||
ANP39441.1 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa) | ||||
ANP39444.1 | Glucokinase; Belongs to the bacterial glucokinase family. (320 aa) | ||||
ANP39457.1 | Keto-deoxy-phosphogluconate aldolase; Catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate. (215 aa) | ||||
edd | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (603 aa) | ||||
zwf | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (483 aa) | ||||
pgi | Glucose-6-phosphate isomerase; Belongs to the GPI family. (536 aa) | ||||
ANP39482.1 | Formate dehydrogenase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1003 aa) | ||||
ANP39483.1 | Formate dehydrogenase. (197 aa) | ||||
ANP39484.1 | Formate dehydrogenase subunit gamma. (404 aa) | ||||
gapA | Erythrose-4-phosphate dehydrogenase; Required for glycolysis; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa) | ||||
ANP39558.1 | Isocitrate dehydrogenase; NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate; Belongs to the monomeric-type IDH family. (737 aa) | ||||
ANP39587.1 | Ribose-5-phosphate isomerase. (149 aa) | ||||
ANP39592.1 | Pyruvate, phosphate dikinase. (854 aa) | ||||
ANP39728.1 | Methyltransferase; Belongs to the trimethylamine methyltransferase family. (519 aa) | ||||
glpX | Type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese. (327 aa) | ||||
ANP39754.1 | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (476 aa) | ||||
prs | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (340 aa) | ||||
ANP39866.1 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1146 aa) | ||||
ANP39951.1 | Septum site-determining protein. (405 aa) | ||||
ANP39957.1 | Class I fructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis. (300 aa) | ||||
ANP39972.1 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (457 aa) | ||||
rpiA | Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (262 aa) | ||||
ANP40064.1 | methylmalonyl-CoA carboxyltransferase. (510 aa) | ||||
ANP40071.1 | acetyl/propionyl-CoA carboxylase subuit alpha. (676 aa) | ||||
ANP40075.1 | methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate. (709 aa) | ||||
glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (431 aa) | ||||
ANP40249.1 | Malate dehydrogenase. (759 aa) | ||||
ANP40267.1 | 3-hydroxyacyl-CoA dehydrogenase. (733 aa) | ||||
ANP40268.1 | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa) | ||||
ANP40312.1 | acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa) | ||||
ANP40313.1 | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (167 aa) | ||||
acsA | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (652 aa) | ||||
fumC | Class II fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa) | ||||
ANP40388.1 | Cysteine synthase A; CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis. (344 aa) | ||||
ANP40450.1 | Trimethylamine methyltransferase; Belongs to the trimethylamine methyltransferase family. (514 aa) | ||||
pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (223 aa) | ||||
ANP40585.1 | 5,10-methylenetetrahydrofolate reductase. (310 aa) | ||||
gltA | Citrate (Si)-synthase; Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Belongs to the citrate synthase family. (431 aa) | ||||
ANP40668.1 | Transketolase; Catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; Belongs to the transketolase family. (673 aa) | ||||
gapA-2 | Erythrose-4-phosphate dehydrogenase; Required for glycolysis; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (333 aa) | ||||
ANP40674.1 | Methylmalonate-semialdehyde dehydrogenase (acylating). (499 aa) | ||||
ANP40684.1 | E3 component of alpha keto acid dehydrogenase complexes LpdC; forms a homodimer; binds one molecule of FAD monomer; catalyzes NAD+-dependent oxidation of dihydrolipoyl cofactors that are covalently linked to the E2 component. (464 aa) | ||||
pgk | Phosphoglycerate kinase; Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; Belongs to the phosphoglycerate kinase family. (396 aa) | ||||
pdhA | Pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (337 aa) | ||||
ANP40702.1 | Pyruvate dehydrogenase complex E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (459 aa) | ||||
ANP40703.1 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (441 aa) | ||||
ANP40704.1 | Serine acetyltransferase. (268 aa) | ||||
ANP40752.1 | Aconitate hydratase. (929 aa) | ||||
ANP40772.1 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (915 aa) | ||||
eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (425 aa) | ||||
tpiA | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (246 aa) | ||||
ANP41026.1 | AMP-dependent synthetase. (510 aa) | ||||
glcB | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (709 aa) | ||||
ANP41184.1 | (R)-hydratase. (147 aa) | ||||
ANP41235.1 | Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. (183 aa) | ||||
ANP41269.1 | S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (370 aa) | ||||
ANP41279.1 | Glyceraldehyde-3-phosphate dehydrogenase; Catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (332 aa) | ||||
ANP41295.1 | Serine acetyltransferase. (260 aa) | ||||
folD | Bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (300 aa) | ||||
fhs | Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (558 aa) | ||||
tal | Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (217 aa) | ||||
gcvP | Glycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (949 aa) | ||||
gcvH | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (119 aa) | ||||
gcvT | Glycine cleavage system protein T; Catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein. (374 aa) | ||||
ANP41383.1 | Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (362 aa) | ||||
pckA | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (532 aa) | ||||
ANP41426.1 | acyl-CoA dehydrogenase. (565 aa) | ||||
ANP41500.1 | Pyruvate kinase; Belongs to the pyruvate kinase family. (481 aa) | ||||
accD | acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (320 aa) | ||||
ANP41728.1 | Serine--glyoxylate aminotransferase. (396 aa) | ||||
ANP41767.1 | Transketolase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (794 aa) | ||||
ANP41784.1 | 2-dehydro-3-deoxygluconokinase. (308 aa) | ||||
gpmI | Phosphoglycerate mutase (2,3-diphosphoglycerate-independent); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (506 aa) | ||||
ANP41809.1 | Dihydrolipoyl dehydrogenase. (452 aa) | ||||
ANP41825.1 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (368 aa) | ||||
ANP42014.1 | Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate. (751 aa) | ||||
ilvA | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (408 aa) | ||||
ANP42150.1 | Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine. (317 aa) | ||||
ANP42157.1 | Phosphoserine phosphatase SerB. (291 aa) | ||||
ANP42158.1 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (381 aa) | ||||
ANP42159.1 | Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (531 aa) | ||||
ANP42164.1 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa) | ||||
ANP42168.1 | enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa) |