(25 nodes) Innate Immune System network (Halopenitus malekzadehii)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

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Your Input:
	SEH58912.1	Calcineurin-like phosphoesterase. (349 aa)
	SEH43511.1	Cytidine deaminase. (136 aa)
	SEH37356.1	V/A-type H+-transporting ATPase subunit I; Belongs to the V-ATPase 116 kDa subunit family. (718 aa)
	atpE	V/A-type H+-transporting ATPase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane. (192 aa)
	atpC	V/A-type H+-transporting ATPase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane. (348 aa)
	atpF	V/A-type H+-transporting ATPase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane. (109 aa)
	atpA	V/A-type H+-transporting ATPase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (590 aa)
	atpB	V/A-type H+-transporting ATPase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (472 aa)
	SEH59704.1	Putative oxidoreductase. (158 aa)
	atpD	V/A-type H+-transporting ATPase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (227 aa)
	SEH37914.1	Adenine phosphoribosyltransferase. (237 aa)
	tuf	Translation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (421 aa)
	mre11	DNA repair exonuclease SbcCD nuclease subunit; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity; Belongs to the MRE11/RAD32 family. (413 aa)
	SEH40721.1	Adenine phosphoribosyltransferase; May catalyze a purine salvage reaction, the substrate is unknown. (189 aa)
	psmA	Proteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (285 aa)
	psmB	Proteasome endopeptidase complex, beta component Threonine peptidase. MEROPS family T01A; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (230 aa)
	psmA-2	Proteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (281 aa)
	SEH45742.1	Thiosulfate dehydrogenase [quinone] large subunit. (184 aa)
	SEH50791.1	Porphobilinogen synthase; Belongs to the ALAD family. (326 aa)
	deoC	Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (219 aa)
	SEH52347.1	Nicotinate phosphoribosyltransferase. (386 aa)
	pgi	Glucose-6-phosphate isomerase; Belongs to the GPI family. (431 aa)
	serS	seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (457 aa)
	SEH56001.1	Thiosulfate dehydrogenase [quinone] large subunit. (186 aa)
	tuf-2	Translation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (423 aa)

Your Current Organism:

Halopenitus malekzadehii

NCBI taxonomy Id: 1267564
Other names: H. malekzadehii, Halopenitus malekzadehii Amoozegar et al. 2013, IBRC-M 10418, KCTC 4045, haloarchaeon CC65, strain CC65

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SEH37356.1	atpA	SAMN05192561_101174	SAMN05192561_101179	V/A-type H+-transporting ATPase subunit I; Belongs to the V-ATPase 116 kDa subunit family.	V/A-type H+-transporting ATPase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.	0.999
SEH37356.1	atpB	SAMN05192561_101174	SAMN05192561_101180	V/A-type H+-transporting ATPase subunit I; Belongs to the V-ATPase 116 kDa subunit family.	V/A-type H+-transporting ATPase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.	0.999
SEH37356.1	atpC	SAMN05192561_101174	SAMN05192561_101177	V/A-type H+-transporting ATPase subunit I; Belongs to the V-ATPase 116 kDa subunit family.	V/A-type H+-transporting ATPase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
SEH37356.1	atpD	SAMN05192561_101174	SAMN05192561_101181	V/A-type H+-transporting ATPase subunit I; Belongs to the V-ATPase 116 kDa subunit family.	V/A-type H+-transporting ATPase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
SEH37356.1	atpE	SAMN05192561_101174	SAMN05192561_101176	V/A-type H+-transporting ATPase subunit I; Belongs to the V-ATPase 116 kDa subunit family.	V/A-type H+-transporting ATPase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
SEH37356.1	atpF	SAMN05192561_101174	SAMN05192561_101178	V/A-type H+-transporting ATPase subunit I; Belongs to the V-ATPase 116 kDa subunit family.	V/A-type H+-transporting ATPase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
SEH37914.1	SEH52347.1	SAMN05192561_101287	SAMN05192561_104125	Adenine phosphoribosyltransferase.	Nicotinate phosphoribosyltransferase.	0.415
SEH37914.1	SEH58912.1	SAMN05192561_101287	SAMN05192561_1105	Adenine phosphoribosyltransferase.	Calcineurin-like phosphoesterase.	0.530
SEH37914.1	mre11	SAMN05192561_101287	SAMN05192561_101455	Adenine phosphoribosyltransferase.	DNA repair exonuclease SbcCD nuclease subunit; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity; Belongs to the MRE11/RAD32 family.	0.541
SEH43511.1	deoC	SAMN05192561_1011042	SAMN05192561_104106	Cytidine deaminase.	Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.	0.854
SEH52347.1	SEH37914.1	SAMN05192561_104125	SAMN05192561_101287	Nicotinate phosphoribosyltransferase.	Adenine phosphoribosyltransferase.	0.415
SEH58912.1	SEH37914.1	SAMN05192561_1105	SAMN05192561_101287	Calcineurin-like phosphoesterase.	Adenine phosphoribosyltransferase.	0.530
atpA	SEH37356.1	SAMN05192561_101179	SAMN05192561_101174	V/A-type H+-transporting ATPase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.	V/A-type H+-transporting ATPase subunit I; Belongs to the V-ATPase 116 kDa subunit family.	0.999
atpA	atpB	SAMN05192561_101179	SAMN05192561_101180	V/A-type H+-transporting ATPase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.	V/A-type H+-transporting ATPase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.	0.999
atpA	atpC	SAMN05192561_101179	SAMN05192561_101177	V/A-type H+-transporting ATPase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.	V/A-type H+-transporting ATPase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
atpA	atpD	SAMN05192561_101179	SAMN05192561_101181	V/A-type H+-transporting ATPase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.	V/A-type H+-transporting ATPase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
atpA	atpE	SAMN05192561_101179	SAMN05192561_101176	V/A-type H+-transporting ATPase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.	V/A-type H+-transporting ATPase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
atpA	atpF	SAMN05192561_101179	SAMN05192561_101178	V/A-type H+-transporting ATPase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.	V/A-type H+-transporting ATPase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
atpA	tuf	SAMN05192561_101179	SAMN05192561_101299	V/A-type H+-transporting ATPase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.	Translation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.	0.481
atpA	tuf-2	SAMN05192561_101179	SAMN05192561_1075	V/A-type H+-transporting ATPase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.	Translation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.	0.481