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polS polS sadH_1 sadH_1 WYH_00066 WYH_00066 sucD sucD mdh mdh hdhA hdhA kefC_1 kefC_1 kefC_2 kefC_2 asd2 asd2 fabG_1 fabG_1 fabG_2 fabG_2 bdhA bdhA yciK yciK gap1 gap1 ilvC ilvC WYH_00439 WYH_00439 qorA qorA csgA csgA ahcY ahcY WYH_00754 WYH_00754 fabI_1 fabI_1 ldh ldh dxr dxr hprA_1 hprA_1 WYH_00964 WYH_00964 pntAA pntAA WYH_01048 WYH_01048 fabG_3 fabG_3 panE panE WYH_01142 WYH_01142 linC linC cysG_1 cysG_1 WYH_01329 WYH_01329 proC proC argC argC WYH_01380 WYH_01380 fabG1 fabG1 WYH_01491 WYH_01491 kch kch zwf zwf fabG_4 fabG_4 xylB_1 xylB_1 gutB gutB kefC_3 kefC_3 dapB dapB fdm fdm WYH_01699 WYH_01699 galE galE tuaD_1 tuaD_1 wbiB wbiB pglF pglF tuaD_2 tuaD_2 xecD xecD rapL rapL ycdF ycdF WYH_01897 WYH_01897 WYH_01905 WYH_01905 ligC ligC sadH_2 sadH_2 fabG_5 fabG_5 adhT adhT ydaD ydaD ald ald phbB phbB gdhB gdhB mmsB mmsB lvr_1 lvr_1 budC budC araA araA ped ped aroE aroE ppsC ppsC wbpA wbpA fabI_2 fabI_2 WYH_02388 WYH_02388 nhaP nhaP fabI_3 fabI_3 hom hom mmgB mmgB tme tme WYH_02517 WYH_02517 hprA_2 hprA_2 WYH_02582 WYH_02582 adh adh WYH_02768 WYH_02768 flhA_1 flhA_1 qorB_1 qorB_1 sadH_3 sadH_3 folD folD lvr_2 lvr_2 gno gno qorB_2 qorB_2 xylB_3 xylB_3 ldhA ldhA lvr_3 lvr_3 sucC_2 sucC_2 gpsA gpsA serA serA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
polSSorbitol dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (291 aa)
sadH_1Putative oxidoreductase SadH; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (330 aa)
WYH_00066Putative oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (280 aa)
sucDSuccinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (296 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa)
hdhA7-alpha-hydroxysteroid dehydrogenase. (254 aa)
kefC_1Glutathione-regulated potassium-efflux system protein KefC; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (588 aa)
kefC_2Glutathione-regulated potassium-efflux system protein KefC; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (567 aa)
asd2Aspartate-semialdehyde dehydrogenase 2; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (341 aa)
fabG_13-oxoacyl-[acyl-carrier-protein] reductase FabG; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (250 aa)
fabG_23-oxoacyl-[acyl-carrier-protein] reductase FabG. (236 aa)
bdhAD-beta-hydroxybutyrate dehydrogenase. (252 aa)
yciKPutative oxidoreductase YciK. (240 aa)
gap1Glyceraldehyde-3-phosphate dehydrogenase 1; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (339 aa)
WYH_00439Glucose 1-dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (242 aa)
qorAQuinone oxidoreductase 1. (329 aa)
csgAC-factor. (243 aa)
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (472 aa)
WYH_00754Carboxynorspermidine synthase. (403 aa)
fabI_1Enoyl-[acyl-carrier-protein] reductase [NADH] FabI. (257 aa)
ldhLeucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (354 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (384 aa)
hprA_1Glycerate dehydrogenase. (311 aa)
WYH_00964Hypothetical protein. (229 aa)
pntAANAD(P) transhydrogenase subunit alpha part 1. (373 aa)
WYH_01048Tartronate semialdehyde reductase. (277 aa)
fabG_33-oxoacyl-[acyl-carrier-protein] reductase FabG. (245 aa)
panE2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (307 aa)
WYH_01142Glycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (322 aa)
linC2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase. (248 aa)
cysG_1Siroheme synthase. (260 aa)
WYH_013293 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase. (287 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (268 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. (308 aa)
WYH_013802-(hydroxymethyl)glutarate dehydrogenase. (300 aa)
fabG13-oxoacyl-[acyl-carrier-protein] reductase FabG1. (260 aa)
WYH_01491Rossmann-like domain protein. (311 aa)
kchVoltage-gated potassium channel Kch. (361 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (488 aa)
fabG_43-oxoacyl-[acyl-carrier-protein] reductase FabG. (279 aa)
xylB_1Aryl-alcohol dehydrogenase. (377 aa)
gutBSorbitol dehydrogenase. (333 aa)
kefC_3Glutathione-regulated potassium-efflux system protein KefC; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (594 aa)
dapB4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (242 aa)
fdmFormaldehyde dismutase. (397 aa)
WYH_01699Short chain dehydrogenase. (137 aa)
galEUDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (335 aa)
tuaD_1UDP-glucose 6-dehydrogenase TuaD. (433 aa)
wbiBdTDP-L-rhamnose 4-epimerase. (339 aa)
pglFUDP-N-acetyl-alpha-D-glucosamine C6 dehydratase. (734 aa)
tuaD_2UDP-glucose 6-dehydrogenase TuaD. (450 aa)
xecD2-(R)-hydroxypropyl-CoM dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (281 aa)
rapLL-lysine cyclodeaminase. (328 aa)
ycdFGlucose 1-dehydrogenase 2. (263 aa)
WYH_018973-beta hydroxysteroid dehydrogenase/isomerase family protein. (315 aa)
WYH_01905NAD binding domain of 6-phosphogluconate dehydrogenase. (269 aa)
ligC4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase. (319 aa)
sadH_2Putative oxidoreductase SadH; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (313 aa)
fabG_53-oxoacyl-[acyl-carrier-protein] reductase FabG. (248 aa)
adhTAlcohol dehydrogenase. (335 aa)
ydaDGeneral stress protein 39. (292 aa)
aldAlanine dehydrogenase; Belongs to the AlaDH/PNT family. (371 aa)
phbBAcetoacetyl-CoA reductase. (240 aa)
gdhBNAD-specific glutamate dehydrogenase. (1569 aa)
mmsB3-hydroxyisobutyrate dehydrogenase. (294 aa)
lvr_1Levodione reductase. (260 aa)
budCDiacetyl reductase. (254 aa)
araAL-arabinose 1-dehydrogenase. (316 aa)
ped(S)-1-Phenylethanol dehydrogenase. (261 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (285 aa)
ppsCPhthiocerol synthesis polyketide synthase type I PpsC. (347 aa)
wbpAUDP-N-acetyl-D-glucosamine 6-dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (436 aa)
fabI_2Enoyl-[acyl-carrier-protein] reductase [NADH] FabI. (274 aa)
WYH_02388Hypothetical protein. (257 aa)
nhaPK(+)/H(+) antiporter NhaP. (618 aa)
fabI_3Enoyl-[acyl-carrier-protein] reductase [NADH] FabI. (257 aa)
homHomoserine dehydrogenase. (435 aa)
mmgBPutative 3-hydroxybutyryl-CoA dehydrogenase. (289 aa)
tmeNADP-dependent malic enzyme. (752 aa)
WYH_02517Glyceraldehyde-3-phosphate dehydrogenase. (349 aa)
hprA_2Glycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (333 aa)
WYH_02582Hypothetical protein. (234 aa)
adhAlcohol dehydrogenase. (331 aa)
WYH_02768Cyclohexadienyl dehydrogenase. (302 aa)
flhA_1S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (370 aa)
qorB_1Quinone oxidoreductase 2. (284 aa)
sadH_3Putative oxidoreductase SadH; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (305 aa)
folDBifunctional protein FolD protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (308 aa)
lvr_2Levodione reductase. (249 aa)
gnoGluconate 5-dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (251 aa)
qorB_2Quinone oxidoreductase 2. (304 aa)
xylB_3Aryl-alcohol dehydrogenase. (382 aa)
ldhAD-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (336 aa)
lvr_3Levodione reductase. (254 aa)
sucC_2Succinyl-CoA ligase [ADP-forming] subunit beta. (706 aa)
gpsAGlycerol-3-phosphate dehydrogenase [NAD(P)+]; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (331 aa)
serAD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (527 aa)
Your Current Organism:
Altererythrobacter atlanticus
NCBI taxonomy Id: 1267766
Other names: A. atlanticus, Altererythrobacter atlanticus Wu et al. 2014, Altererythrobacter sp. 26DY36, CGMCC 1.12411, JCM 18865, strain 26DY36
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