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| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (315 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (255 aa) |
| | fbp | D-fructose 1,6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (385 aa) |
| | ALL00110.1 | Putative transcriptional regulator; COG1709. (243 aa) |
| | ALL00176.1 | Putative deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (192 aa) |
| | guaA | Putative GMP synthase, amidotransferase subunit; Catalyzes the synthesis of GMP from XMP. (497 aa) |
| | ALL00195.1 | Putative inosine-5'-monophosphate dehydrogenase; COG0516. (468 aa) |
| | ALL00223.1 | Putative phosphoserine phosphatase; COG0560. (229 aa) |
| | ALL00289.1 | Putative hydroxymethylglutaryl-CoA synthase; COG3425; Belongs to the thiolase-like superfamily. UPF0219 family. (349 aa) |
| | ALL00290.1 | Acetyl-CoA acetyltransferase; COG0183. (384 aa) |
| | ALL00291.1 | Hypothetical protein; COG1545. (146 aa) |
| | ALL00292.1 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; COG1257; Belongs to the HMG-CoA reductase family. (422 aa) |
| | ALL00317.1 | Pyruvate:ferredoxin oxidoreductase, beta subunit; COG1013. (317 aa) |
| | ALL00318.1 | Pyruvate:ferredoxin oxidoreductase, alpha subunit; COG0674. (415 aa) |
| | ALL00319.1 | Pyruvate:ferredoxin oxidoreductase, delta subunit; COG1144. (113 aa) |
| | ALL00320.1 | Pyruvate:ferredoxin oxidoreductase, gamma subunit; COG1014. (192 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (312 aa) |
| | ALL00333.1 | Putative glutamate synthase; COG0069. (703 aa) |
| | ALL00334.1 | Putative glutamate synthase, subunit alpha; COG0070. (610 aa) |
| | ALL00339.1 | IMP biosynthesis protein PurP domain containing protein; COG1759. (351 aa) |
| | ALL00371.1 | Aspartate aminotransferase; COG0436. (396 aa) |
| | ALL00382.1 | Glycerate 2-kinase; COG2379. (464 aa) |
| | ALL00416.1 | Acetyl-coenzyme A synthetase; COG0365. (668 aa) |
| | ALL00420.1 | Lysine biosynthesis protein LysX; COG0189. (280 aa) |
| | carB | Carbamoyl-phosphate synthase large chain; COG0458; Belongs to the CarB family. (1073 aa) |
| | carA | Carbamoyl-phosphate synthase small chain; COG0505; Belongs to the CarA family. (395 aa) |
| | ALL00423.1 | Argininosuccinate lyase; COG0165. (465 aa) |
| | argG | Argininosuccinate synthase; COG0137; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (396 aa) |
| | ALL00426.1 | Aspartate-semialdehyde dehydrogenase; COG0136. (356 aa) |
| | ALL00427.1 | Aspartokinase; COG0527; Belongs to the aspartokinase family. (459 aa) |
| | ALL00428.1 | Putative homoserine dehydrogenase; COG0460. (343 aa) |
| | pdxT | Pyridoxal phosphate synthase yaaE subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (200 aa) |
| | pdxS | Pyridoxal phosphate synthase yaaD subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (355 aa) |
| | ALL00473.1 | Putative 3-hydroxyacyl-CoA dehydrogenase; COG1250; Belongs to the enoyl-CoA hydratase/isomerase family. (673 aa) |
| | ALL00474.1 | acyl-CoA dehydrogenase; COG1960. (402 aa) |
| | ALL00475.1 | Hypothetical protein; COG1545. (181 aa) |
| | ALL00476.1 | Acetyl-CoA acetyltransferase; COG0183. (393 aa) |
| | ALL00477.1 | Putative sterol carrier protein; COG3255. (112 aa) |
| | ALL00479.1 | Electron transfer flavoprotein, alpha subunit; COG2025. (306 aa) |
| | ALL00480.1 | Electron transfer flavoprotein beta subunit; COG2086. (266 aa) |
| | trpB | Pyridoxal-phosphate dependent TrpB-like protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (450 aa) |
| | ALL00588.1 | Putative aldehyde ferredoxin oxidoreductase; COG2414. (633 aa) |
| | ALL00706.1 | Putative dihydroorotase; COG0044. (414 aa) |
| | ALL00707.1 | Dihydroorotate dehydrogenase electron transfer subunit; COG0543. (262 aa) |
| | pyrI | Aspartate carbamoyltransferase regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. (164 aa) |
| | pyrB | Aspartate carbamoyltransferase catalytic subunit; COG0540. (323 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (204 aa) |
| | ALL00711.1 | Orotidine 5'-phosphate decarboxylase; COG0284. (227 aa) |
| | ALL00725.1 | Diaminopimelate aminotransferase; COG0624. (412 aa) |
| | ALL00730.1 | Hexulose-6-phosphate synthase; COG0269. (232 aa) |
| | ALL00799.1 | IMP biosynthesis protein PurP domain containing protein; COG1759. (376 aa) |
| | ALL00800.1 | acetyl-CoA synthetase. (237 aa) |
| | ALL00803.1 | 2-isopropylmalate synthase; COG0119; Belongs to the alpha-IPM synthase/homocitrate synthase family. (560 aa) |
| | ALL00839.1 | Adenylosuccinate lyase; COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (467 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (338 aa) |
| | sucD | Succinyl-CoA ligase [ADP-forming] alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (289 aa) |
| | sucC | Succinyl-CoA ligase [ADP-forming] beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (385 aa) |
| | pyrD | Dihydroorotate dehydrogenase, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (302 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (139 aa) |
| | ALL00947.1 | Bifunctional phosphoglucose/phosphomannose isomerase. (334 aa) |
| | ALL00966.1 | Aspartate aminotransferase; COG0436. (400 aa) |
| | aroE | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (284 aa) |
| | ALL00981.1 | Indole-3-glycerol phosphate synthase; COG0134. (259 aa) |
| | ALL00982.1 | Anthranilate synthase, amidotransferase component; COG0512. (196 aa) |
| | ALL00983.1 | Anthranilate synthase, aminase component; COG0147. (430 aa) |
| | trpF | Phosphoribosyl anthranilate isomerase; COG0135; Belongs to the TrpF family. (220 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (348 aa) |
| | trpB-2 | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (433 aa) |
| | ALL00987.1 | Tryptophan synthase alpha chain; COG0159. (255 aa) |
| | ALL00988.1 | Dihydrolipoamide dehydrogenase; COG1249. (459 aa) |
| | aroD | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (226 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (371 aa) |
| | ALL00991.1 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; COG2876. (272 aa) |
| | ALL00992.1 | Transketolase, N-terminal region; COG3959. (319 aa) |
| | ALL00993.1 | Transketolase, C-terminal region; COG3958. (326 aa) |
| | ALL00994.1 | Prephenate dehydrogenase; COG0287. (348 aa) |
| | aroC | Putative chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (386 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (435 aa) |
| | aroK | Putative shikimate kinase II; COG1685. (290 aa) |
| | surE | Stationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (284 aa) |
| | ALL01033.1 | Ribose 5-phosphate isomerase A; COG0120. (249 aa) |
| | ALL01090.1 | Acetolactate synthase, small subunit. (136 aa) |
| | ALL01107.1 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (813 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (438 aa) |
| | ALL01134.1 | 3-hexulose-6-phosphate isomerase; COG0794. (200 aa) |
| | ALL01172.1 | Ornithine carbamoyltransferase; COG0078; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (313 aa) |
| | ALL01179.1 | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, archaeal type; COG3635. (428 aa) |
| | ALL01181.1 | Glutamine synthetase type I; COG0174; Belongs to the glutamine synthetase family. (463 aa) |
| | ALL01224.1 | Ribokinase; COG0524. (309 aa) |
| | ALL01226.1 | Glycine cleavage system protein P, C-terminal domain; COG1003. (519 aa) |
| | gcvPA | Glycine cleavage system protein P, N-terminal domain; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (479 aa) |
| | ALL01283.1 | Acetyl-CoA carboxylase, carboxyltransferase component; COG4799. (518 aa) |
| | ALL01284.1 | Hypothetical protein. (154 aa) |
| | ALL01285.1 | Pyruvate carboxyl transferase subunit A; COG4770. (491 aa) |
| | ALL01286.1 | Hypothetical protein; COG0340. (257 aa) |
| | ALL01362.1 | Phosphatidylserine synthase; COG1183; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (231 aa) |
| | hisF | Imidazole glycerol phosphate synthase cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (258 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (427 aa) |
| | hisE | phosphoribosyl-ATP pyrophosphatase; COG0140. (101 aa) |
| | ALL01420.1 | Imidazole glycerol phosphate synthase amidotransferase subunit; COG0118. (206 aa) |
| | ALL01421.1 | Phosphoribosyl-AMP cyclohydrolase; COG0139. (265 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase; COG0131. (200 aa) |
| | ALL01428.1 | Hypothetical protein; COG0106; Belongs to the HisA/HisF family. (249 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (295 aa) |
| | ALL01470.1 | Phosphoribosylformylglycinamidine cyclo-ligase; COG0150. (339 aa) |
| | purT | Phosphoribosylaminoimidazole carboxylase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (411 aa) |
| | ALL01473.1 | Phosphoribosylamine/glycine ligase; COG0151. (492 aa) |
| | ALL01474.1 | Amidophosphoribosyltransferase. (407 aa) |
| | purF | Glutamine amidotransferase class-II; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (451 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase, synthetase subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is t [...] (725 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ a [...] (225 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, PurS subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (84 aa) |
| | ALL01489.1 | Pyruvate:ferredoxin oxidoreductase, gamma subunit; COG1014. (213 aa) |
| | ALL01490.1 | Pyruvate:ferredoxin oxidoreductase, delta subunit; COG1144. (117 aa) |
| | ALL01491.1 | Pyruvate:ferredoxin oxidoreductase, alpha subunit; COG0674. (411 aa) |
| | ALL01492.1 | Pyruvate:ferredoxin oxidoreductase, beta subunit; COG1013. (306 aa) |
| | ALL01495.1 | Acylphosphatase; COG1254. (106 aa) |
| | ALL01496.1 | Decarboxylase; COG0076. (393 aa) |
| | ALL01511.1 | Prephenate dehydratase; COG0077. (276 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (138 aa) |
| | ALL01564.1 | Hypothetical protein. (338 aa) |
| | ALL01579.1 | Isocitrate dehydrogenase; COG0473. (344 aa) |
| | leuD | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (170 aa) |
| | leuC | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (437 aa) |
| | ALL01582.1 | Isopropylmalate/homocitrate/citramalate synthase-like protein; COG0119. (432 aa) |
| | ALL01589.1 | 3-phosphoglycerate dehydrogenase; COG0111; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (342 aa) |
| | ALL01604.1 | Glycine cleavage system aminomethyltransferase T; COG0404. (378 aa) |
| | ALL01627.1 | Hypothetical protein. (438 aa) |
| | ALL01640.1 | Glyoxylate reductase; COG1052; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (339 aa) |
| | ALL01641.1 | NADP-specific glutamate dehydrogenase; COG0334; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (422 aa) |
| | ALL01654.1 | 4-aminobutyrate aminotransferase; COG0160; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (458 aa) |
| | mvk | Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (317 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (446 aa) |
| | gap | NAD(P)-dependent glyceraldehyde 3-phosphate dehydrogenase; COG0057. (343 aa) |
| | pgk | Phosphoglycerate kinase; COG0126; Belongs to the phosphoglycerate kinase family. (422 aa) |
| | glmS | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (613 aa) |
| | ALL01756.1 | 2-oxoglutarate oxidoreductase, alpha subunit; COG0674. (630 aa) |
| | ALL01757.1 | 2-oxoglutarate oxidoreductase, beta subunit; COG1013. (320 aa) |
| | ALL01759.1 | Pyruvate kinase; COG0469; Belongs to the pyruvate kinase family. (466 aa) |
| | ALL01772.1 | Acyl-CoA synthetase (NDP forming); COG1042. (479 aa) |
| | ALL01780.1 | Homocitrate synthase; COG0119; Belongs to the alpha-IPM synthase/homocitrate synthase family. (497 aa) |
| | hisC | Histidinol-phosphate aminotransferase; COG0079. (364 aa) |
| | ALL01810.1 | Succinyl-diaminopimelate desuccinylase; COG0624. (406 aa) |
| | ALL01827.1 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (432 aa) |
| | ALL01850.1 | Glutamate synthase small subunit; COG0493. (344 aa) |
| | ALL01870.1 | Carbamate kinase; COG0549; Belongs to the carbamate kinase family. (318 aa) |
| | lysZ | N-acetylglutamate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily. (273 aa) |
| | lysY | N-acetyl-gamma-aminoadipyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. (352 aa) |
| | ALL01879.1 | Putative lysine biosynthesis protein LysW. (60 aa) |
| | ALL01880.1 | Putative lysine biosynthesis protein LysX; COG0189. (284 aa) |
| | lysJ | Putative acetylornithine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. (395 aa) |
| | lysK | N-acetyl-lysine deacetylase; Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine. (362 aa) |
| | ALL01968.1 | NADP-dependent malic enzyme; COG0281. (460 aa) |
| | leuD-2 | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (180 aa) |
| | ilvD | Dihydroxy-acid dehydratase; COG0129; Belongs to the IlvD/Edd family. (573 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (327 aa) |
| | ALL01972.1 | Hypothetical protein. (83 aa) |
| | ALL01973.1 | Acetolactate synthase large subunit; COG0028. (582 aa) |
| | ALL01974.1 | 2-isopropylmalate synthase; COG0119. (366 aa) |
| | ALL01975.1 | 3-isopropylmalate dehydrogenase; COG0473. (335 aa) |
| | leuC-2 | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (425 aa) |
