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| | dnaB | Helicase DnaB; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (463 aa) |
| | AIF39715.1 | Single-stranded DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa) |
| | AIF39751.1 | Chromosome partitioning protein ParB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ParB family. (413 aa) |
| | dnaA | Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (501 aa) |
| | AIF39758.1 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (376 aa) |
| | recF | DNA recombination protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (440 aa) |
| | AIF39762.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (64 aa) |
| | gyrB | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (713 aa) |
| | gyrA | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (931 aa) |
| | AIF39765.1 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa) |
| | AIF39795.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa) |
| | AIF39819.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa) |
| | AIF39850.1 | DNA lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPG family. (287 aa) |
| | xth | Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa) |
| | xseB | Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (113 aa) |
| | xseA | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (479 aa) |
| | AIF40332.1 | UvrD/REP helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1117 aa) |
| | AIF40333.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the helicase family. UvrD subfamily. (1176 aa) |
| | AIF40335.1 | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (708 aa) |
| | ssb | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (168 aa) |
| | AIF40515.1 | DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1797 aa) |
| | recA | Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (364 aa) |
| | holA | DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa) |
| | lexA | ArsR family transcriptional regulator; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (238 aa) |
| | dnaE | DNA polymerase III subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1182 aa) |
| | AIF40589.1 | Endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (608 aa) |
| | AIF40601.1 | DNA polymerase III subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DNA polymerase type-C family. DnaE2 subfamily. (1248 aa) |
| | dinB | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (382 aa) |
| | AIF40606.1 | DNA topoisomerase IV subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. (709 aa) |
| | AIF40610.1 | DNA topoisomerase IV subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. (866 aa) |
| | AIF40667.1 | ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa) |
| | AIF40672.1 | ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa) |
| | AIF40693.1 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa) |
| | ruvA | ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (201 aa) |
| | ruvB | ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (364 aa) |
| | xerC | Tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (298 aa) |
| | AIF40708.1 | Chromosome partitioning protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa) |
| | AIF40709.1 | Chromosome segregation protein ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. (318 aa) |
| | scpB | Transcriptional regulator; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (207 aa) |
| | AIF40711.1 | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (303 aa) |
| | cmk | Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa) |
| | der | GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (486 aa) |
| | AIF40741.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1196 aa) |
| | sbcD | Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (397 aa) |
| | AIF40780.1 | 5'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa) |
| | dinB-2 | DNA repair nucleotidyltransferase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (476 aa) |
| | AIF40817.1 | DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (703 aa) |
| | uvrC | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (667 aa) |
| | uvrB | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (701 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (195 aa) |
| | AIF40872.1 | BCCT transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (787 aa) |
| | AIF40873.1 | Aspartate aminotransferase; Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa) |
| | polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (889 aa) |
| | priA | Hypothetical protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (810 aa) |
| | AIF40943.1 | Phosphopantothenoylcysteine decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa) |
| | AIF40977.1 | ADP-ribose pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa) |
| | recN | DNA recombination protein RecN; May be involved in recombinational repair of damaged DNA. (583 aa) |
| | nadK | Inorganic polyphosphate kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (302 aa) |
| | AIF40981.1 | Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa) |
| | AIF40982.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (98 aa) |
| | AIF40983.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HAD-like hydrolase superfamily. (321 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (661 aa) |
| | recO | DNA recombination protein RecO; Involved in DNA repair and RecF pathway recombination. (269 aa) |
| | smc | Hypothetical protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. (152 aa) |
| | mutM | 5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (348 aa) |
| | coaD | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (161 aa) |
| | rsmD | Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa) |
| | AIF41194.1 | ATP-dependent DNA helicase RecG; Derived by automated computational analysis using gene prediction method: Protein Homology. (729 aa) |
| | AIF41338.1 | Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa) |
| | pcrA | ATP-dependent DNA helicase PcrA; Derived by automated computational analysis using gene prediction method: Protein Homology. (898 aa) |
| | coaA | Pantothenate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa) |
| | mfd | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1209 aa) |
| | AIF41415.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (522 aa) |
| | pth | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. (192 aa) |
| | AIF41420.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (62 aa) |
| | AIF41452.1 | Endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa) |
| | AIF41543.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa) |
| | AIF41554.1 | DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPG family. (289 aa) |
| | radA | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (459 aa) |
| | ku | DNA repair protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (264 aa) |
| | AIF41619.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa) |
| | AIF41620.1 | ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa) |
| | AIF41644.1 | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa) |
| | topA | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (940 aa) |
| | recR | Recombinase RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (199 aa) |
| | AIF41705.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1151 aa) |
| | AIF41748.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1119 aa) |
| | AIF41760.1 | NUDIX hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa) |
| | AIF41766.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa) |
| | AIF41767.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (101 aa) |
| | AIF41794.1 | Excinuclease ABC subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. (899 aa) |
