(48 nodes) Mixed, incl. Establishment of Sister Chromatid Cohesion, and Melanoma-associated antigen network (Trichechus manatus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101344510	Condensin complex subunit 2. (603 aa)
	LOC101351461	Double-strand-break repair protein rad21-like protein 1. (555 aa)
	LOC101354567	Structural maintenance of chromosomes protein. (1191 aa)
	LOC101347651	Necdin. (327 aa)
	LOC101361502	Double-strand-break repair protein rad21 homolog. (631 aa)
	LOC101342486	Structural maintenance of chromosomes protein. (1217 aa)
	LOC101358220	Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (387 aa)
	LOC101345280	Condensin complex subunit 3. (1015 aa)
	LOC101350457	Structural maintenance of chromosomes protein 5 isoform X1. (1110 aa)
	LOC101347853	Structural maintenance of chromosomes protein. (1234 aa)
	LOC101349965	Melanoma-associated antigen E2. (526 aa)
	LOC101359212	Melanoma-associated antigen 10-like. (354 aa)
	LOC101356057	N-acetyltransferase ESCO2. (614 aa)
	LOC101359046	MAU2 chromatid cohesion factor homolog isoform X1. (612 aa)
	LOC101342884	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1375 aa)
	LOC101354040	N-acetyltransferase ESCO1 isoform X1. (848 aa)
	LOC101344252	Nipped-B protein. (2803 aa)
	LOC101340606	Melanoma-associated antigen D2. (596 aa)
	LOC101359509	Structural maintenance of chromosomes protein. (1233 aa)
	LOC101354736	Melanoma-associated antigen B3-like. (362 aa)
	LOC101346559	Melanoma-associated antigen B16-like. (349 aa)
	LOC101354568	Melanoma-associated antigen 10-like. (332 aa)
	LOC101356363	Melanoma-associated antigen 10-like. (300 aa)
	LOC105756155	Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (367 aa)
	LOC101359989	Melanoma-associated antigen 10-like. (358 aa)
	LOC105756066	Non-structural maintenance of chromosomes element 3 homolog. (295 aa)
	LOC101361277	Melanoma-associated antigen 10-like. (481 aa)
	LOC101353166	LOW QUALITY PROTEIN: melanoma-associated antigen F1. (318 aa)
	LOC101342190	Sororin. (251 aa)
	LOC101355069	Meiotic recombination protein REC8 homolog. (567 aa)
	LOC101358468	LOW QUALITY PROTEIN: melanoma-associated antigen B5-like. (353 aa)
	LOC101344107	Condensin-2 complex subunit G2 isoform X1. (1140 aa)
	LOC111819949	E3 SUMO-protein ligase NSE2-like isoform X1. (142 aa)
	LOC111819950	E3 SUMO-protein ligase NSE2. (90 aa)
	LOC101352983	Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. (1528 aa)
	LOC101346585	Cohesin subunit SA-2 isoform X1. (1268 aa)
	LOC101359476	Melanoma-associated antigen 10-like. (384 aa)
	LOC101347849	Structural maintenance of chromosomes protein. (1223 aa)
	LOC101340734	Cohesin subunit SA-1 isoform X1. (1325 aa)
	LOC101348617	Condensin-2 complex subunit H2 isoform X1. (639 aa)
	LOC101358677	Putative MAGE domain-containing protein MAGEA13P. (331 aa)
	LOC101342033	Wings apart-like protein homolog isoform X1. (1196 aa)
	LOC101360794	Cohesin subunit SA-3. (1224 aa)
	LOC101349055	Sister chromatid cohesion protein PDS5 homolog B isoform X1. (1456 aa)
	LOC101354863	Sister chromatid cohesion protein PDS5 homolog A isoform X1. (1352 aa)
	LOC101343910	Structural maintenance of chromosomes protein 6 isoform X1. (1090 aa)
	LOC101355383	Non-structural maintenance of chromosomes element 1 homolog isoform X2. (282 aa)
	LOC101343919	LOW QUALITY PROTEIN: trophinin. (1175 aa)

Your Current Organism:

Trichechus manatus

NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101340606	LOC101342486	A0A2Y9E8E3	A0A2Y9DHS0	Melanoma-associated antigen D2.	Structural maintenance of chromosomes protein.	0.430
LOC101340606	LOC101343910	A0A2Y9E8E3	A0A2Y9RSI2	Melanoma-associated antigen D2.	Structural maintenance of chromosomes protein 6 isoform X1.	0.709
LOC101340606	LOC101350457	A0A2Y9E8E3	A0A2Y9DJP7	Melanoma-associated antigen D2.	Structural maintenance of chromosomes protein 5 isoform X1.	0.714
LOC101340606	LOC101355383	A0A2Y9E8E3	A0A2Y9RXG6	Melanoma-associated antigen D2.	Non-structural maintenance of chromosomes element 1 homolog isoform X2.	0.754
LOC101340606	LOC101358220	A0A2Y9E8E3	A0A2Y9DHW4	Melanoma-associated antigen D2.	Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.	0.675
LOC101340606	LOC105756155	A0A2Y9E8E3	A0A2Y9FVU7	Melanoma-associated antigen D2.	Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.	0.675
LOC101340606	LOC111819949	A0A2Y9E8E3	A0A2Y9QPM1	Melanoma-associated antigen D2.	E3 SUMO-protein ligase NSE2-like isoform X1.	0.608
LOC101340606	LOC111819950	A0A2Y9E8E3	A0A2Y9QRE6	Melanoma-associated antigen D2.	E3 SUMO-protein ligase NSE2.	0.608
LOC101340734	LOC101342033	A0A2Y9R8N8	A0A2Y9RM06	Cohesin subunit SA-1 isoform X1.	Wings apart-like protein homolog isoform X1.	0.942
LOC101340734	LOC101342190	A0A2Y9R8N8	A0A2Y9G319	Cohesin subunit SA-1 isoform X1.	Sororin.	0.780
LOC101340734	LOC101342486	A0A2Y9R8N8	A0A2Y9DHS0	Cohesin subunit SA-1 isoform X1.	Structural maintenance of chromosomes protein.	0.998
LOC101340734	LOC101343910	A0A2Y9R8N8	A0A2Y9RSI2	Cohesin subunit SA-1 isoform X1.	Structural maintenance of chromosomes protein 6 isoform X1.	0.801
LOC101340734	LOC101344252	A0A2Y9R8N8	A0A2Y9E7K2	Cohesin subunit SA-1 isoform X1.	Nipped-B protein.	0.913
LOC101340734	LOC101346585	A0A2Y9R8N8	A0A2Y9R3F9	Cohesin subunit SA-1 isoform X1.	Cohesin subunit SA-2 isoform X1.	0.991
LOC101340734	LOC101347849	A0A2Y9R8N8	A0A2Y9R878	Cohesin subunit SA-1 isoform X1.	Structural maintenance of chromosomes protein.	0.748
LOC101340734	LOC101347853	A0A2Y9R8N8	A0A2Y9DT16	Cohesin subunit SA-1 isoform X1.	Structural maintenance of chromosomes protein.	0.982
LOC101340734	LOC101349055	A0A2Y9R8N8	A0A2Y9RR11	Cohesin subunit SA-1 isoform X1.	Sister chromatid cohesion protein PDS5 homolog B isoform X1.	0.898
LOC101340734	LOC101350457	A0A2Y9R8N8	A0A2Y9DJP7	Cohesin subunit SA-1 isoform X1.	Structural maintenance of chromosomes protein 5 isoform X1.	0.776
LOC101340734	LOC101351461	A0A2Y9R8N8	A0A2Y9D9R9	Cohesin subunit SA-1 isoform X1.	Double-strand-break repair protein rad21-like protein 1.	0.898
LOC101340734	LOC101354040	A0A2Y9R8N8	A0A2Y9E662	Cohesin subunit SA-1 isoform X1.	N-acetyltransferase ESCO1 isoform X1.	0.777