25 items (Trichechus manatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101342442	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (335 aa)
	LOC101357665	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
	LOC111822149	Putative serine/threonine-protein kinase PRKY. (77 aa)
	LOC111822155	Uncharacterized protein LOC111822155. (366 aa)
	LOC101351895	Angiopoietin-1 receptor isoform X1. (1129 aa)
	LOC101345849	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
	LOC101354903	Prokineticin-1. (105 aa)
	LOC101347797	V-set and transmembrane domain-containing protein 4. (395 aa)
	LOC101354466	LOW QUALITY PROTEIN: X-box-binding protein 1. (386 aa)
	LOC101347312	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
	LOC101346202	Notch-regulated ankyrin repeat-containing protein. (114 aa)
	LOC101351477	Integrin beta-1-binding protein 1. (200 aa)
	LOC101348356	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1037 aa)
	LOC101355264	Ephrin type-A receptor 2. (977 aa)
	LOC101353165	THAP domain-containing protein 1. (213 aa)
	LOC101348699	Lysyl oxidase homolog 2 isoform X1. (773 aa)
	LOC101355990	cAMP-dependent protein kinase catalytic subunit PRKX isoform X1; Belongs to the protein kinase superfamily. (353 aa)
	LOC101341602	Neurofibromin isoform X1. (2841 aa)
	LOC101344413	BMP-binding endothelial regulator protein. (685 aa)
	LOC101358678	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1082 aa)
	LOC101343540	Scavenger receptor class B member 1; Belongs to the CD36 family. (507 aa)
	LOC101349686	Prokineticin-2 isoform X1. (129 aa)
	LOC101359953	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (499 aa)
	LOC101352446	Serine/threonine-protein kinase/endoribonuclease IRE1. (976 aa)
	LOC101347663	LOW QUALITY PROTEIN: NADPH oxidase 5. (737 aa)

Your Current Organism:

Trichechus manatus

NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101342442	LOC101351895	A0A2Y9RXT9	A0A2Y9S0P2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Angiopoietin-1 receptor isoform X1.	0.838
LOC101342442	LOC101355264	A0A2Y9RXT9	A0A2Y9DM78	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Ephrin type-A receptor 2.	0.678
LOC101342442	LOC101357665	A0A2Y9RXT9	A0A2Y9E4P4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.463
LOC101342442	LOC101358678	A0A2Y9RXT9	A0A2Y9RBH4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family.	0.401
LOC101343540	LOC101355264	A0A2Y9RKP8	A0A2Y9DM78	Scavenger receptor class B member 1; Belongs to the CD36 family.	Ephrin type-A receptor 2.	0.568
LOC101344413	LOC101348356	A0A2Y9E391	A0A2Y9QZI2	BMP-binding endothelial regulator protein.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.481
LOC101345849	LOC101347312	A0A2Y9E9U7	A0A2Y9G3U6	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.996
LOC101347312	LOC101345849	A0A2Y9G3U6	A0A2Y9E9U7	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.996
LOC101348356	LOC101344413	A0A2Y9QZI2	A0A2Y9E391	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	BMP-binding endothelial regulator protein.	0.481
LOC101348356	LOC101359953	A0A2Y9QZI2	A0A2Y9DDC6	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.623
LOC101351895	LOC101342442	A0A2Y9S0P2	A0A2Y9RXT9	Angiopoietin-1 receptor isoform X1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.838
LOC101351895	LOC101357665	A0A2Y9S0P2	A0A2Y9E4P4	Angiopoietin-1 receptor isoform X1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.776
LOC101351895	LOC101358678	A0A2Y9S0P2	A0A2Y9RBH4	Angiopoietin-1 receptor isoform X1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family.	0.556
LOC101352446	LOC101354466	A0A2Y9DGQ0	A0A2Y9G104	Serine/threonine-protein kinase/endoribonuclease IRE1.	LOW QUALITY PROTEIN: X-box-binding protein 1.	0.972
LOC101354466	LOC101352446	A0A2Y9G104	A0A2Y9DGQ0	LOW QUALITY PROTEIN: X-box-binding protein 1.	Serine/threonine-protein kinase/endoribonuclease IRE1.	0.972
LOC101355264	LOC101342442	A0A2Y9DM78	A0A2Y9RXT9	Ephrin type-A receptor 2.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.678
LOC101355264	LOC101343540	A0A2Y9DM78	A0A2Y9RKP8	Ephrin type-A receptor 2.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.568
LOC101355264	LOC101357665	A0A2Y9DM78	A0A2Y9E4P4	Ephrin type-A receptor 2.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.675
LOC101357665	LOC101342442	A0A2Y9E4P4	A0A2Y9RXT9	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.463
LOC101357665	LOC101351895	A0A2Y9E4P4	A0A2Y9S0P2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Angiopoietin-1 receptor isoform X1.	0.776