STRINGSTRING
LOC101345578 LOC101345578 LOC101346179 LOC101346179 LOC101343911 LOC101343911 LOC101347376 LOC101347376 LOC101343915 LOC101343915 LOC101345760 LOC101345760 LOC101348057 LOC101348057 LOC101356277 LOC101356277 LOC101355570 LOC101355570 LOC101342974 LOC101342974 LOC101359341 LOC101359341 LOC101357687 LOC101357687 LOC101358115 LOC101358115 LOC101352501 LOC101352501 LOC101340794 LOC101340794 LOC101340528 LOC101340528 LOC101356451 LOC101356451 LOC101343938 LOC101343938 LOC101350790 LOC101350790 LOC101351050 LOC101351050 LOC101345874 LOC101345874 LOC101345360 LOC101345360 LOC101350547 LOC101350547 LOC101355857 LOC101355857 LOC101354831 LOC101354831 LOC101360053 LOC101360053 LOC101341571 LOC101341571 LOC101353647 LOC101353647 LOC101354423 LOC101354423 LOC101359453 LOC101359453 LOC101351409 LOC101351409 LOC101355098 LOC101355098 LOC101340711 LOC101340711 LOC101355263 LOC101355263 LOC101360406 LOC101360406 LOC101347340 LOC101347340 LOC101344541 LOC101344541 LOC101353236 LOC101353236 LOC101349116 LOC101349116 LOC101349027 LOC101349027 LOC101355699 LOC101355699 LOC101343957 LOC101343957 LOC101355870 LOC101355870 LOC101360497 LOC101360497 LOC101345210 LOC101345210 LOC101343706 LOC101343706 LOC101354431 LOC101354431 LOC101347092 LOC101347092 LOC101341664 LOC101341664 LOC101345723 LOC101345723 LOC101352027 LOC101352027 LOC101355452 LOC101355452 LOC101344311 LOC101344311 LOC101346925 LOC101346925 LOC101345383 LOC101345383 LOC101342770 LOC101342770 LOC101361883 LOC101361883 LOC101340572 LOC101340572 LOC101345725 LOC101345725 LOC101354194 LOC101354194 LOC101344977 LOC101344977 LOC101355212 LOC101355212 LOC101341851 LOC101341851 LOC101352041 LOC101352041 LOC101340743 LOC101340743 LOC101348378 LOC101348378 LOC101353176 LOC101353176 LOC101356665 LOC101356665 LOC101361213 LOC101361213 LOC101356256 LOC101356256 LOC101346525 LOC101346525 LOC101360706 LOC101360706 LOC101351272 LOC101351272 LOC101351010 LOC101351010 LOC101351891 LOC101351891 LOC101354294 LOC101354294 LOC101340332 LOC101340332 LOC101347875 LOC101347875 LOC101349843 LOC101349843 LOC101359672 LOC101359672 LOC101358352 LOC101358352 LOC101346700 LOC101346700 LOC101357089 LOC101357089 LOC101349065 LOC101349065 LOC101349673 LOC101349673 LOC101343395 LOC101343395 LOC101357686 LOC101357686 LOC101350174 LOC101350174 LOC101349508 LOC101349508 LOC101361745 LOC101361745 LOC101358102 LOC101358102 LOC101349952 LOC101349952 LOC101351672 LOC101351672 LOC101346894 LOC101346894 LOC101343001 LOC101343001 LOC101344555 LOC101344555 LOC101359409 LOC101359409 LOC101345425 LOC101345425 LOC101361408 LOC101361408 LOC101358646 LOC101358646 LOC101347137 LOC101347137 LOC101345086 LOC101345086 LOC101356355 LOC101356355 LOC101359695 LOC101359695 LOC101341558 LOC101341558 LOC101344607 LOC101344607 LOC101357622 LOC101357622 LOC101359690 LOC101359690 LOC101347243 LOC101347243 LOC101340669 LOC101340669 LOC101347391 LOC101347391 LOC101346283 LOC101346283 LOC101351988 LOC101351988 LOC101361337 LOC101361337 LOC101350052 LOC101350052 LOC101351212 LOC101351212 LOC101348349 LOC101348349 LOC101349796 LOC101349796 LOC101361776 LOC101361776 LOC101343178 LOC101343178 LOC101353816 LOC101353816 LOC101345528 LOC101345528 LOC101360851 LOC101360851 LOC101349628 LOC101349628 LOC101351852 LOC101351852 LOC101342244 LOC101342244 LOC101345298 LOC101345298 LOC101354927 LOC101354927 LOC101360670 LOC101360670 LOC101359379 LOC101359379 LOC101349375 LOC101349375 LOC101351693 LOC101351693 LOC101346494 LOC101346494 LOC101352468 LOC101352468 LOC101352807 LOC101352807 LOC101349714 LOC101349714 LOC101345997 LOC101345997 LOC101357581 LOC101357581 LOC101357241 LOC101357241 LOC101346600 LOC101346600 LOC101355642 LOC101355642 LOC101357918 LOC101357918 LOC105756546 LOC105756546 LOC101348210 LOC101348210 LOC101345486 LOC101345486 LOC101345407 LOC101345407 LOC101346435 LOC101346435 LOC105756878 LOC105756878 LOC101346865 LOC101346865 LOC101344995 LOC101344995 LOC101348226 LOC101348226
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101345578Synaptopodin-2 isoform X1. (1262 aa)
LOC101346179Ras-related protein Rab-7a. (207 aa)
LOC101343911Ras-related protein Rab-43. (212 aa)
LOC101347376Testis-expressed protein 264 isoform X1. (312 aa)
LOC101343915Ancient ubiquitous protein 1. (461 aa)
LOC101345760Ras-related protein Rab-1A. (205 aa)
LOC101348057Transmembrane protein 41B. (291 aa)
LOC101356277Microtubule-associated proteins 1A/1B light chain 3A. (121 aa)
LOC101355570Tumor protein p53-inducible nuclear protein 2. (221 aa)
LOC101342974Transmembrane protein 74. (305 aa)
LOC101359341Beclin 1-associated autophagy-related key regulator. (492 aa)
LOC101357687Vesicle transport through interaction with t-SNAREs homolog 1B isoform X1. (232 aa)
LOC101358115Charged multivesicular body protein 4b. (224 aa)
LOC101352501NSFL1 cofactor p47 isoform X1. (372 aa)
LOC101340794Nucleotide-binding oligomerization domain-containing protein 2 isoform X1. (1013 aa)
LOC101340528Sorting nexin-30. (437 aa)
LOC101356451Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family. (806 aa)
LOC101343938E3 UFM1-protein ligase 1 isoform X1. (793 aa)
LOC101350790UBX domain-containing protein 2B isoform X1. (331 aa)
LOC101351050Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
LOC101345874WD repeat domain phosphoinositide-interacting protein 1 isoform X1. (446 aa)
LOC101345360Charged multivesicular body protein 6. (201 aa)
LOC101350547Ubiquitin-like-conjugating enzyme ATG10. (220 aa)
LOC101355857BAG family molecular chaperone regulator 3. (576 aa)
LOC101354831Protein limb expression 1 homolog. (282 aa)
LOC101360053Serine/threonine-protein kinase ULK3; Belongs to the protein kinase superfamily. (472 aa)
LOC101341571Ubiquitin thioesterase OTU1. (348 aa)
LOC101353647Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta; Belongs to the PI3/PI4-kinase family. (1633 aa)
LOC101354423Pejvakin. (352 aa)
LOC101359453Gamma-aminobutyric acid receptor-associated protein. (117 aa)
LOC101351409Microtubule-associated proteins 1A/1B light chain 3C-like. (147 aa)
LOC101355098ER membrane protein complex subunit 6. (110 aa)
LOC101340711WD repeat-containing protein 81 isoform X1. (1938 aa)
LOC101355263Autophagy-related protein 2 homolog B. (2078 aa)
LOC101360406Syntaxin-12 isoform X1; Belongs to the syntaxin family. (274 aa)
LOC101347340UBX domain-containing protein 2A. (258 aa)
LOC101344541Serine/threonine-protein kinase PINK1, mitochondrial. (582 aa)
LOC101353236Microtubule-associated proteins 1A/1B light chain 3B. (125 aa)
LOC101349116Phosphatidylinositol 5-phosphate 4-kinase type-2 beta. (416 aa)
LOC101349027Nucleotide-binding oligomerization domain-containing protein 1. (953 aa)
LOC101355699Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (473 aa)
LOC101343957Mucolipin-1. (578 aa)
LOC101355870Vacuole membrane protein 1. (406 aa)
LOC101360497UBX domain-containing protein 6. (389 aa)
LOC101345210Charged multivesicular body protein 1b-2. (199 aa)
LOC101343706Lysosome-associated membrane glycoprotein 2 isoform X1. (413 aa)
LOC101354431Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
LOC101347092Histone deacetylase 10. (704 aa)
LOC101341664UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit isoform X1. (1046 aa)
LOC101345723Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1. (406 aa)
LOC101352027LIX1-like protein isoform X1. (335 aa)
LOC101355452vam6/Vps39-like protein isoform X1. (889 aa)
LOC101344311Spatacsin isoform X1. (2443 aa)
LOC101346925Tectonin beta-propeller repeat-containing protein 1. (1160 aa)
LOC101345383Serine/threonine-protein kinase ULK2 isoform X1. (1038 aa)
LOC101342770Stimulator of interferon genes protein. (387 aa)
LOC101361883UV radiation resistance-associated gene protein. (700 aa)
LOC101340572Charged multivesicular body protein 7. (450 aa)
LOC101345725Phosphoinositide 3-kinase regulatory subunit 4 isoform X1. (1358 aa)
LOC101354194Ras-related protein Rab-19. (216 aa)
LOC101344977DDRGK domain-containing protein 1. (315 aa)
LOC101355212Ras-related protein Rab-1B. (201 aa)
LOC101341851Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (839 aa)
LOC101352041Starch-binding domain-containing protein 1. (359 aa)
LOC101340743V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (833 aa)
LOC101348378Reticulophagy regulator 1 isoform X1. (483 aa)
LOC101353176Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (860 aa)
LOC101356665Vacuolar protein sorting-associated protein 33A isoform X1; Belongs to the STXBP/unc-18/SEC1 family. (596 aa)
LOC101361213Charged multivesicular body protein 4c. (232 aa)
LOC101356256Synaptosomal-associated protein 29. (253 aa)
LOC101346525Gamma-aminobutyric acid receptor-associated protein-like 1. (117 aa)
LOC101360706Battenin. (438 aa)
LOC101351272Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (393 aa)
LOC101351010Sequestosome-1 isoform X1. (440 aa)
LOC101351891RB1-inducible coiled-coil protein 1 isoform X1. (1592 aa)
LOC101354294Ras-related protein Rab-23. (237 aa)
LOC101340332AP-4 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (453 aa)
LOC101347875Gamma-aminobutyric acid receptor-associated protein-like 2. (117 aa)
LOC101349843Phospholipase A-2-activating protein isoform X1. (796 aa)
LOC101359672Charged multivesicular body protein 3. (221 aa)
LOC101358352Prohibitin. (299 aa)
LOC101346700SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
LOC101357089UPF0600 protein C5orf51 homolog isoform X1. (296 aa)
LOC101349065UPF0577 protein KIAA1324 homolog isoform X1. (1013 aa)
LOC101349673Major facilitator superfamily domain-containing protein 8. (522 aa)
LOC101343395Sorting nexin-14 isoform X1. (966 aa)
LOC101357686Uncharacterized protein C6orf106 homolog isoform X1. (291 aa)
LOC101350174Autophagy-related protein 16-1 isoform X1. (607 aa)
LOC101349508Ubiquitin-fold modifier-conjugating enzyme 1; E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage. (167 aa)
LOC101361745Reticulophagy regulator 3. (466 aa)
LOC101358102Laforin isoform X1. (327 aa)
LOC101349952LOW QUALITY PROTEIN: beclin-2. (363 aa)
LOC101351672Microtubule-associated proteins 1A/1B light chain 3C. (127 aa)
LOC101346894Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (940 aa)
LOC101343001LOW QUALITY PROTEIN: reticulophagy regulator 2. (520 aa)
LOC101344555Ectopic P granules protein 5 homolog. (2578 aa)
LOC101359409Niemann-Pick C1 protein. (1277 aa)
LOC101345425WD repeat and FYVE domain-containing protein 3 isoform X1. (3517 aa)
LOC101361408Tumor protein p53-inducible nuclear protein 1 isoform X1. (241 aa)
LOC101358646Zinc finger FYVE domain-containing protein 26. (2543 aa)
LOC101347137Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (469 aa)
LOC101345086Tafazzin family protein; Some isoforms may be involved in cardiolipin metabolism. (297 aa)
LOC101356355Next to BRCA1 gene 1 protein. (959 aa)
LOC101359695Syntaxin-17; Belongs to the syntaxin family. (302 aa)
LOC101341558Charged multivesicular body protein 5. (131 aa)
LOC101344607Pleckstrin homology domain-containing family M member 1-like. (308 aa)
LOC101357622Autophagy-related protein 3. (318 aa)
LOC101359690Beclin-1 isoform X1. (448 aa)
LOC101347243Vesicle transport through interaction with t-SNAREs homolog 1A isoform X1. (217 aa)
LOC101340669RBR-type E3 ubiquitin transferase. (347 aa)
LOC101347391Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (537 aa)
LOC101346283Zinc finger FYVE domain-containing protein 1 isoform X1. (779 aa)
LOC101351988Charged multivesicular body protein 2b. (165 aa)
LOC101361337WD repeat domain phosphoinositide-interacting protein 3 isoform X1. (324 aa)
LOC101350052Protein RUBCNL-like isoform X1. (665 aa)
LOC101351212Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
LOC101348349Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
LOC101349796Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (839 aa)
LOC101361776Calcium-binding and coiled-coil domain-containing protein 2. (453 aa)
LOC101343178WD repeat domain phosphoinositide-interacting protein 4 isoform X1. (382 aa)
LOC101353816Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1179 aa)
LOC101345528Pleckstrin homology domain-containing family M member 1. (936 aa)
LOC101360851Sorting nexin-7. (310 aa)
LOC101349628Spermatogenesis-associated protein 33. (190 aa)
LOC101351852Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (392 aa)
LOC101342244RUN and FYVE domain-containing protein 4 isoform X1. (597 aa)
LOC101345298Phosphatidylinositol 3-kinase catalytic subunit type 3. (914 aa)
LOC101354927Phosphofurin acidic cluster sorting protein 2. (828 aa)
LOC101360670Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
LOC101359379WD repeat domain phosphoinositide-interacting protein 2 isoform X1. (445 aa)
LOC101349375Charged multivesicular body protein 1a isoform X1. (230 aa)
LOC101351693E3 ubiquitin-protein ligase. (756 aa)
LOC101346494Etoposide-induced protein 2.4 homolog. (340 aa)
LOC101352468Autophagy-related protein 16-2 isoform X1. (623 aa)
LOC101352807Fructose-2,6-bisphosphatase TIGAR isoform X1. (270 aa)
LOC101349714Ubiquitin-like modifier-activating enzyme 5 isoform X1. (404 aa)
LOC101345997Autophagy-related protein 2 homolog A. (1926 aa)
LOC101357581Serine/threonine-protein kinase ULK1. (1323 aa)
LOC101357241TBC1 domain family member 5 isoform X1. (860 aa)
LOC101346600Charged multivesicular body protein 1b. (199 aa)
LOC101355642Charged multivesicular body protein 2a. (222 aa)
LOC101357918Ubiquitin-like protein ATG12. (78 aa)
LOC105756546Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (728 aa)
LOC101348210Trafficking protein particle complex subunit 8 isoform X1. (1465 aa)
LOC101345486Ras-related protein Rab-33B isoform X1. (242 aa)
LOC101345407Activating molecule in BECN1-regulated autophagy protein 1 isoform X1. (1299 aa)
LOC101346435Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (550 aa)
LOC105756878Ubiquitin-fold modifier 1. (60 aa)
LOC101346865Autophagy-related protein 101. (218 aa)
LOC101344995Vesicle-associated membrane protein 8. (101 aa)
LOC101348226Arfaptin-2 isoform X1. (341 aa)
Your Current Organism:
Trichechus manatus
NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris
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