42 items (Trichechus manatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101341158	Adenomatous polyposis coli protein isoform X1. (2856 aa)
	LOC101343817	Ras-related protein Rab-13. (203 aa)
	LOC101341786	Ras GTPase-activating-like protein IQGAP3. (1632 aa)
	LOC101346027	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (406 aa)
	LOC101358981	Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (1203 aa)
	LOC101360471	Prestin; Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (741 aa)
	LOC101341943	MAGUK p55 subfamily member 7; Belongs to the MAGUK family. (576 aa)
	LOC101344069	LOW QUALITY PROTEIN: microtubule cross-linking factor 1. (1583 aa)
	LOC101353682	Segment polarity protein dishevelled homolog DVL-1 isoform X1. (700 aa)
	LOC101353406	Coronin; Belongs to the WD repeat coronin family. (474 aa)
	LOC101354727	Epithelial cell adhesion molecule. (317 aa)
	LOC101343649	Receptor-type tyrosine-protein phosphatase O isoform X1. (1216 aa)
	LOC101349039	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
	LOC101354358	Neuronal vesicle trafficking-associated protein 1 isoform X2. (185 aa)
	LOC101344890	ADP-ribosylation factor-like protein 2; Belongs to the small GTPase superfamily. Arf family. (184 aa)
	LOC101342027	Solute carrier family 12 member 2 isoform X1. (1204 aa)
	LOC101357820	Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
	LOC101354352	Claudin-12. (244 aa)
	LOC101340566	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
	LOC101341495	Vang-like protein. (524 aa)
	LOC101360939	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (283 aa)
	LOC101340309	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
	LOC101344875	Unconventional myosin-Ia; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1043 aa)
	LOC101358758	Basigin isoform X1. (385 aa)
	LOC101343697	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2021 aa)
	LOC101342326	Unconventional myosin-Ic; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1063 aa)
	LOC101358927	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
	LOC101352110	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
	LOC101361593	Monocarboxylate transporter 4. (467 aa)
	LOC101356960	Tubulin-specific chaperone D. (1199 aa)
	LOC101349430	Blood vessel epicardial substance. (360 aa)
	LOC101361150	Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
	LOC101349668	Tumor-associated calcium signal transducer 2. (418 aa)
	LOC101347718	Leptin receptor isoform X1. (1162 aa)
	LOC101351897	Catenin beta-1. (781 aa)
	LOC101346985	Axin-1 isoform X1. (878 aa)
	LOC101351796	Guanine nucleotide-binding protein subunit alpha-12. (394 aa)
	LOC101353113	Vang-like protein. (522 aa)
	LOC101354955	Annexin. (133 aa)
	LOC101344726	Protein naked cuticle homolog 2. (470 aa)
	LOC101349689	Polycystin-1. (4306 aa)
	LOC101355739	A-kinase anchoring protein 7 isoform X1. (481 aa)

Your Current Organism:

Trichechus manatus

NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101340309	LOC101340566	A0A2Y9DTC0	A0A2Y9DUK4	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.655
LOC101340309	LOC101346027	A0A2Y9DTC0	A0A2Y9EAF9	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.758
LOC101340309	LOC101349039	A0A2Y9DTC0	A0A2Y9DXA2	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.771
LOC101340309	LOC101354352	A0A2Y9DTC0	A0A2Y9DW41	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin-12.	0.405
LOC101340309	LOC101358927	A0A2Y9DTC0	A0A2Y9DK30	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.765
LOC101340566	LOC101340309	A0A2Y9DUK4	A0A2Y9DTC0	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.655
LOC101340566	LOC101346027	A0A2Y9DUK4	A0A2Y9EAF9	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.758
LOC101340566	LOC101349039	A0A2Y9DUK4	A0A2Y9DXA2	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.771
LOC101340566	LOC101354352	A0A2Y9DUK4	A0A2Y9DW41	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin-12.	0.405
LOC101340566	LOC101358927	A0A2Y9DUK4	A0A2Y9DK30	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.765
LOC101341158	LOC101346985	A0A2Y9QWJ4	A0A2Y9QRX4	Adenomatous polyposis coli protein isoform X1.	Axin-1 isoform X1.	0.998
LOC101341158	LOC101351897	A0A2Y9QWJ4	A0A2Y9D636	Adenomatous polyposis coli protein isoform X1.	Catenin beta-1.	0.999
LOC101341158	LOC101353682	A0A2Y9QWJ4	A0A2Y9RJF9	Adenomatous polyposis coli protein isoform X1.	Segment polarity protein dishevelled homolog DVL-1 isoform X1.	0.962
LOC101341495	LOC101341943	A0A2Y9DTR1	A0A2Y9RPB0	Vang-like protein.	MAGUK p55 subfamily member 7; Belongs to the MAGUK family.	0.456
LOC101341495	LOC101351897	A0A2Y9DTR1	A0A2Y9D636	Vang-like protein.	Catenin beta-1.	0.488
LOC101341495	LOC101353113	A0A2Y9DTR1	A0A2Y9G1R2	Vang-like protein.	Vang-like protein.	0.925
LOC101341495	LOC101353682	A0A2Y9DTR1	A0A2Y9RJF9	Vang-like protein.	Segment polarity protein dishevelled homolog DVL-1 isoform X1.	0.981
LOC101341495	LOC101357820	A0A2Y9DTR1	A0A2Y9DX85	Vang-like protein.	Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family.	0.536
LOC101341786	LOC101351897	A0A2Y9E7Q6	A0A2Y9D636	Ras GTPase-activating-like protein IQGAP3.	Catenin beta-1.	0.593
LOC101341943	LOC101341495	A0A2Y9RPB0	A0A2Y9DTR1	MAGUK p55 subfamily member 7; Belongs to the MAGUK family.	Vang-like protein.	0.456