STRINGSTRING
LOC101362047 LOC101362047 LOC101353092 LOC101353092 LOC101345241 LOC101345241 LOC101344989 LOC101344989 LOC101348562 LOC101348562 LOC101347301 LOC101347301 LOC101349084 LOC101349084 LOC101356182 LOC101356182 LOC101357687 LOC101357687 LOC101359777 LOC101359777 LOC101346883 LOC101346883 LOC101359432 LOC101359432 LOC101347398 LOC101347398 LOC101347740 LOC101347740 LOC101350704 LOC101350704 LOC101349353 LOC101349353 LOC101360219 LOC101360219 LOC101342071 LOC101342071 LOC101355338 LOC101355338 LOC101340807 LOC101340807 LOC101346124 LOC101346124 LOC101342073 LOC101342073 LOC101342400 LOC101342400 LOC101356034 LOC101356034 LOC101361089 LOC101361089 LOC101358484 LOC101358484 LOC101341154 LOC101341154 LOC101357292 LOC101357292 LOC101357881 LOC101357881 LOC101354175 LOC101354175 LOC101341739 LOC101341739 LOC101354339 LOC101354339 LOC101356386 LOC101356386 LOC101352199 LOC101352199 LOC101355010 LOC101355010 LOC101344719 LOC101344719 LOC101349387 LOC101349387 LOC101361876 LOC101361876 LOC101358068 LOC101358068 LOC101356319 LOC101356319 LOC101347181 LOC101347181 LOC101357135 LOC101357135 LOC101346758 LOC101346758 LOC101361280 LOC101361280 LOC101358416 LOC101358416 LOC101352295 LOC101352295 LOC101345562 LOC101345562 LOC101352042 LOC101352042 LOC101360867 LOC101360867 LOC101352394 LOC101352394 LOC101361802 LOC101361802 LOC101348891 LOC101348891 LOC101340584 LOC101340584 LOC101361548 LOC101361548 LOC101348633 LOC101348633 LOC101345574 LOC101345574 LOC101349910 LOC101349910 LOC101348976 LOC101348976 LOC101340861 LOC101340861 LOC101351446 LOC101351446 LOC101360966 LOC101360966 LOC101345834 LOC101345834 LOC101343985 LOC101343985 LOC101341783 LOC101341783 LOC101347879 LOC101347879 LOC101360985 LOC101360985 LOC101345517 LOC101345517 LOC101354933 LOC101354933 LOC101346187 LOC101346187 LOC101352082 LOC101352082 LOC101341455 LOC101341455 LOC101341889 LOC101341889 LOC101359695 LOC101359695 LOC101345514 LOC101345514 LOC101347243 LOC101347243 LOC101358564 LOC101358564 LOC101349200 LOC101349200 LOC101342585 LOC101342585 LOC101343950 LOC101343950 LOC101347416 LOC101347416 LOC101340410 LOC101340410 LOC101347262 LOC101347262 LOC101361627 LOC101361627 LOC101359118 LOC101359118 LOC101340472 LOC101340472 LOC101355307 LOC101355307 LOC101352805 LOC101352805 LOC101343451 LOC101343451 LOC101342551 LOC101342551 LOC101351101 LOC101351101 LOC101359909 LOC101359909 LOC101356500 LOC101356500 LOC101359408 LOC101359408 LOC101345823 LOC101345823 LOC101345320 LOC101345320 LOC101341861 LOC101341861 LOC101349072 LOC101349072 LOC101346357 LOC101346357
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101362047Epsin-1. (575 aa)
LOC101353092Protein SEC13 homolog; Belongs to the WD repeat SEC13 family. (322 aa)
LOC101345241Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (874 aa)
LOC101344989Sterol regulatory element-binding protein cleavage-activating protein isoform X1. (1283 aa)
LOC101348562SH3-containing GRB2-like protein 3-interacting protein 1 isoform X1. (834 aa)
LOC101347301Aftiphilin isoform X3. (935 aa)
LOC101349084V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (369 aa)
LOC101356182V-type proton ATPase subunit D isoform X1. (247 aa)
LOC101357687Vesicle transport through interaction with t-SNAREs homolog 1B isoform X1. (232 aa)
LOC101359777AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1102 aa)
LOC101346883Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (211 aa)
LOC101359432V-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family. (205 aa)
LOC101347398Peflin. (285 aa)
LOC101347740Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (218 aa)
LOC101350704Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
LOC101349353Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (1057 aa)
LOC101360219V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
LOC1013420715,6-dihydroxyindole-2-carboxylic acid oxidase. (537 aa)
LOC101355338V-type proton ATPase catalytic subunit A isoform X1. (618 aa)
LOC101340807ER lumen protein-retaining receptor. (223 aa)
LOC101346124ENTH domain-containing protein 1. (611 aa)
LOC101342073Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (177 aa)
LOC101342400Golgi SNAP receptor complex member 2 isoform X1; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. (212 aa)
LOC101356034AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1088 aa)
LOC101361089Kelch-like protein 12 isoform X1. (564 aa)
LOC101358484DENN domain-containing protein 1A. (1018 aa)
LOC101341154Ribonuclease kappa. (98 aa)
LOC101357292Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (767 aa)
LOC101357881AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (154 aa)
LOC101354175Uncharacterized protein CLBA1. (334 aa)
LOC101341739Renin receptor. (350 aa)
LOC101354339Adaptin ear-binding coat-associated protein 2 isoform X1. (263 aa)
LOC101356386Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa)
LOC101352199Epsin-3. (641 aa)
LOC101355010Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (283 aa)
LOC101344719Proline-rich protein 15-like protein. (100 aa)
LOC101349387Neurogranin. (182 aa)
LOC101361876Sterol regulatory element-binding protein 2. (1134 aa)
LOC101358068Programmed cell death protein 6 isoform X1. (187 aa)
LOC101356319ER lumen protein-retaining receptor. (150 aa)
LOC101347181Epsin-2. (641 aa)
LOC101357135Vesicle-trafficking protein SEC22b; Belongs to the synaptobrevin family. (215 aa)
LOC101346758AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (956 aa)
LOC101361280ER lumen protein-retaining receptor. (212 aa)
LOC101358416Testis-specific gene 13 protein. (283 aa)
LOC101352295Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (871 aa)
LOC101345562V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa)
LOC101352042Protein transport protein Sec24C. (1097 aa)
LOC101360867Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family. (308 aa)
LOC101352394AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (423 aa)
LOC101361802N-terminal kinase-like protein isoform X1. (806 aa)
LOC101348891GTP-binding protein SAR1b isoform X1; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
LOC101340584Transmembrane emp24 domain-containing protein 2. (201 aa)
LOC101361548Deleted in autism protein 1. (430 aa)
LOC101348633Protein transport protein Sec24A isoform X1. (1103 aa)
LOC101345574Drebrin-like protein isoform X1. (433 aa)
LOC101349910Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (511 aa)
LOC101348976AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
LOC101340861Transmembrane emp24 domain-containing protein 3. (218 aa)
LOC101351446AP complex subunit beta. (938 aa)
LOC101360966Adaptin ear-binding coat-associated protein 1 isoform X1. (275 aa)
LOC101345834Disabled homolog 2. (770 aa)
LOC101343985Cell migration-inducing and hyaluronan-binding protein. (1361 aa)
LOC101341783Vesicular acetylcholine transporter. (532 aa)
LOC101347879Synaptotagmin-11. (431 aa)
LOC101360985Coatomer subunit alpha. (1047 aa)
LOC101345517V-type proton ATPase subunit S1. (466 aa)
LOC101354933AP-1 complex subunit mu-2 isoform X1; Belongs to the adaptor complexes medium subunit family. (425 aa)
LOC101346187AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (940 aa)
LOC101352082Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1851 aa)
LOC101341455V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (838 aa)
LOC101341889AP-1 complex subunit gamma. (841 aa)
LOC101359695Syntaxin-17; Belongs to the syntaxin family. (302 aa)
LOC101345514Clathrin interactor 1 isoform X1. (650 aa)
LOC101347243Vesicle transport through interaction with t-SNAREs homolog 1A isoform X1. (217 aa)
LOC101358564Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (197 aa)
LOC101349200Synergin gamma isoform X1. (1415 aa)
LOC101342585AP-4 complex accessory subunit tepsin. (452 aa)
LOC101343950Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (427 aa)
LOC101347416V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (497 aa)
LOC101340410Clathrin heavy chain linker domain-containing protein 1. (483 aa)
LOC101347262Protein transport protein Sec24B isoform X5. (1207 aa)
LOC101361627AP-2 complex subunit mu isoform X1; Belongs to the adaptor complexes medium subunit family. (435 aa)
LOC101359118Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (918 aa)
LOC101340472AP-2 complex subunit sigma isoform X1. (172 aa)
LOC101355307Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (958 aa)
LOC101352805Sterol regulatory element-binding protein 1. (1187 aa)
LOC101343451Protein transport protein Sec31A isoform X1. (1270 aa)
LOC101342551LOW QUALITY PROTEIN: protein transport protein Sec31B. (1184 aa)
LOC101351101AP complex subunit beta. (951 aa)
LOC101359909General vesicular transport factor p115 isoform X1. (873 aa)
LOC101356500GTP-binding protein SAR1a; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
LOC101359408AP-1 complex subunit gamma. (827 aa)
LOC101345823Vesicle-associated membrane protein 3. (111 aa)
LOC101345320Protein transport protein Sec24D. (1033 aa)
LOC101341861AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (160 aa)
LOC101349072Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (2371 aa)
LOC101346357Ras association domain-containing protein 9. (414 aa)
Your Current Organism:
Trichechus manatus
NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris
Server load: low (22%) [HD]