STRINGSTRING
LOC101346978 LOC101346978 LOC101340794 LOC101340794 LOC101344352 LOC101344352 LOC101348825 LOC101348825 LOC101360631 LOC101360631 LOC101355304 LOC101355304 LOC101345067 LOC101345067 LOC101351541 LOC101351541 LOC101361406 LOC101361406 LOC111822843 LOC111822843 LOC101341295 LOC101341295 LOC101355495 LOC101355495 LOC101341361 LOC101341361 LOC101343045 LOC101343045 LOC101351368 LOC101351368 LOC101346535 LOC101346535 LOC101359149 LOC101359149 LOC101343372 LOC101343372 LOC101359418 LOC101359418 LOC101352936 LOC101352936 LOC101347634 LOC101347634 LOC101345921 LOC101345921 LOC101358343 LOC101358343 LOC101351806 LOC101351806 LOC101357918 LOC101357918 LOC101351890 LOC101351890 LOC101350754 LOC101350754 LOC101356569 LOC101356569 LOC101360445 LOC101360445 LOC111822326 LOC111822326 LOC111822280 LOC111822280 LOC101351630 LOC101351630 LOC101354697 LOC101354697 LOC101360166 LOC101360166 LOC101349905 LOC101349905 LOC101352286 LOC101352286 LOC101361950 LOC101361950 LOC101344056 LOC101344056 LOC101346158 LOC101346158 LOC101357895 LOC101357895 LOC101355439 LOC101355439 LOC101345902 LOC101345902 LOC101344029 LOC101344029 LOC101347509 LOC101347509 LOC101354508 LOC101354508 LOC101353752 LOC101353752 LOC101352786 LOC101352786 LOC111820491 LOC111820491 LOC101347071 LOC101347071 LOC101348668 LOC101348668 LOC101360839 LOC101360839 LOC101361519 LOC101361519 LOC101348349 LOC101348349 LOC101346309 LOC101346309 LOC101351212 LOC101351212 LOC101340273 LOC101340273 LOC101356462 LOC101356462 LOC111819394 LOC111819394 LOC111819382 LOC111819382 LOC101361752 LOC101361752 LOC101341806 LOC101341806 LOC101349352 LOC101349352 LOC111819379 LOC111819379 LOC111819360 LOC111819360 LOC101357443 LOC101357443 LOC111819201 LOC111819201 LOC105756958 LOC105756958 LOC105756001 LOC105756001 LOC101349601 LOC101349601 LOC101351301 LOC101351301 LOC101360569 LOC101360569 LOC101342306 LOC101342306 LOC111819392 LOC111819392 LOC101361497 LOC101361497 LOC101346982 LOC101346982 LOC101349867 LOC101349867 LOC105757002 LOC105757002 LOC111819362 LOC111819362 LOC101351735 LOC101351735 LOC101344268 LOC101344268 LOC101348743 LOC101348743 LOC105757003 LOC105757003 LOC111819380 LOC111819380 LOC101346289 LOC101346289 LOC111819361 LOC111819361 LOC101349863 LOC101349863 LOC101354659 LOC101354659 LOC101340311 LOC101340311 LOC101346964 LOC101346964 LOC101349348 LOC101349348 LOC101357919 LOC101357919 LOC101355274 LOC101355274 LOC101343892 LOC101343892 LOC101358775 LOC101358775 LOC101352321 LOC101352321 LOC101345689 LOC101345689 LOC101346715 LOC101346715 LOC101343315 LOC101343315 LOC101344931 LOC101344931 LOC101351297 LOC101351297 LOC101357350 LOC101357350 LOC101349076 LOC101349076 LOC101350673 LOC101350673 LOC101352675 LOC101352675 LOC101355231 LOC101355231 LOC101360020 LOC101360020 LOC101361050 LOC101361050 LOC101343385 LOC101343385 LOC101354375 LOC101354375 LOC101348980 LOC101348980 LOC101348209 LOC101348209 LOC101354708 LOC101354708 LOC101357663 LOC101357663 LOC101356832 LOC101356832 LOC101345747 LOC101345747 LOC101354614 LOC101354614 LOC101360960 LOC101360960 LOC101342871 LOC101342871 LOC101355290 LOC101355290 LOC101352734 LOC101352734 LOC101357146 LOC101357146 LOC101349901 LOC101349901 LOC101348880 LOC101348880 LOC101351430 LOC101351430 LOC101359826 LOC101359826 LOC101349136 LOC101349136 LOC101342936 LOC101342936 LOC101359119 LOC101359119 LOC101342770 LOC101342770 LOC101343104 LOC101343104 LOC101362039 LOC101362039 LOC101343790 LOC101343790 LOC101347430 LOC101347430 LOC101353758 LOC101353758 LOC101347761 LOC101347761 LOC101360682 LOC101360682 LOC101348948 LOC101348948 LOC101348865 LOC101348865 LOC101357471 LOC101357471 LOC101357378 LOC101357378 LOC101341330 LOC101341330 LOC101352974 LOC101352974 LOC101346393 LOC101346393 LOC101342084 LOC101342084 LOC101351238 LOC101351238 LOC101345286 LOC101345286 LOC101361517 LOC101361517 LOC101340547 LOC101340547 LOC101358577 LOC101358577 LOC101342748 LOC101342748 LOC101341906 LOC101341906 LOC101346733 LOC101346733 LOC101344211 LOC101344211 LOC101344779 LOC101344779 LOC101348760 LOC101348760 LOC101361336 LOC101361336 LOC101355851 LOC101355851 LOC101343320 LOC101343320 LOC101348242 LOC101348242 LOC101352861 LOC101352861
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101346978Low-density lipoprotein receptor-related protein 8. (955 aa)
LOC101340794Nucleotide-binding oligomerization domain-containing protein 2 isoform X1. (1013 aa)
LOC101344352Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa)
LOC101348825Zinc finger CCHC domain-containing protein 3. (401 aa)
LOC101360631NLR family CARD domain-containing protein 4 isoform X1. (1024 aa)
LOC101355304Arginase. (330 aa)
LOC101345067Tumor necrosis factor alpha-induced protein 3 isoform X1. (790 aa)
LOC101351541Toll-like receptor 9 isoform X1. (1323 aa)
LOC101361406NFX1-type zinc finger-containing protein 1. (1926 aa)
LOC111822843Poliovirus receptor homolog. (171 aa)
LOC101341295Z-DNA-binding protein 1 isoform X1. (290 aa)
LOC101355495Cytotoxic and regulatory T-cell molecule. (374 aa)
LOC101341361LOW QUALITY PROTEIN: killer cell lectin-like receptor subfamily F member 1. (219 aa)
LOC101343045Ficolin-1. (313 aa)
LOC101351368Natural killer cells antigen CD94-like. (196 aa)
LOC101346535TYRO protein tyrosine kinase-binding protein. (118 aa)
LOC101359149Serine/threonine-protein kinase RIO3; Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. (514 aa)
LOC101343372NLR family member X1 isoform X1. (975 aa)
LOC101359418Plasma protease C1 inhibitor; Belongs to the serpin family. (508 aa)
LOC101352936LOW QUALITY PROTEIN: ficolin-1-like. (311 aa)
LOC101347634Akirin-2 isoform X1. (233 aa)
LOC101345921LOW QUALITY PROTEIN: C-type lectin domain family 6 member A. (208 aa)
LOC101358343E3 ubiquitin-protein ligase RNF135 isoform X1. (424 aa)
LOC101351806Tyrosine-protein kinase. (685 aa)
LOC101357918Ubiquitin-like protein ATG12. (78 aa)
LOC101351890NKG2-D type II integral membrane protein-like. (172 aa)
LOC101350754Killer cell lectin-like receptor subfamily B member 1. (230 aa)
LOC101356569Barrier-to-autointegration factor. (89 aa)
LOC101360445Interleukin; Belongs to the IL-15/IL-21 family. (178 aa)
LOC111822326LOW QUALITY PROTEIN: killer cell lectin-like receptor subfamily E member 1. (229 aa)
LOC111822280Cytokine-dependent hematopoietic cell linker-like. (105 aa)
LOC101351630Natural killer cells antigen CD94-like. (254 aa)
LOC101354697Tyrosine-protein kinase. (529 aa)
LOC101360166CCR4-NOT transcription complex subunit 7 isoform X1. (319 aa)
LOC101349905triokinase/FMN cyclase. (578 aa)
LOC101352286Tyrosine-protein kinase receptor TYRO3. (1053 aa)
LOC101361950non-POU domain-containing octamer-binding protein. (472 aa)
LOC101344056Lysosome-associated membrane glycoprotein 1 isoform X1. (416 aa)
LOC101346158Proepiregulin. (98 aa)
LOC101357895CD160 antigen. (183 aa)
LOC101355439LOW QUALITY PROTEIN: T-cell surface protein tactile. (404 aa)
LOC101345902Serine/threonine-protein kinase TBK1 isoform X1. (758 aa)
LOC101344029Dual specificity protein phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa)
LOC101347509Proto-oncogene vav. (841 aa)
LOC101354508YTH domain-containing family protein 2 isoform X1. (625 aa)
LOC101353752Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (238 aa)
LOC101352786Phosphoinositide 3-kinase regulatory subunit 6. (422 aa)
LOC111820491Phosphoinositide 3-kinase regulatory subunit 6-like. (196 aa)
LOC101347071Poly [ADP-ribose] polymerase. (675 aa)
LOC101348668Sulfhydryl oxidase. (254 aa)
LOC101360839Disintegrin and metalloproteinase domain-containing protein 8. (857 aa)
LOC101361519Tyrosine-protein kinase. (527 aa)
LOC101348349Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
LOC101346309Polyglutamine-binding protein 1. (265 aa)
LOC101351212Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
LOC101340273Protein NLRC5 isoform X1. (1863 aa)
LOC101356462Nuclear factor erythroid 2-related factor 2 isoform X1. (622 aa)
LOC111819394NKG2-A/NKG2-B type II integral membrane protein-like. (169 aa)
LOC111819382NKG2-A/NKG2-B type II integral membrane protein-like. (183 aa)
LOC101361752NKG2-A/NKG2-B type II integral membrane protein-like. (191 aa)
LOC101341806Paraspeckle component 1 isoform X1. (521 aa)
LOC101349352Natural killer cells antigen CD94-like. (179 aa)
LOC111819379NKG2-A/NKG2-B type II integral membrane protein-like. (183 aa)
LOC111819360NKG2-A/NKG2-B type II integral membrane protein-like. (187 aa)
LOC101357443LOW QUALITY PROTEIN: natural cytotoxicity triggering receptor 3. (187 aa)
LOC111819201LOW QUALITY PROTEIN: interferon-inducible protein AIM2-like. (136 aa)
LOC105756958Myeloid cell nuclear differentiation antigen-like. (197 aa)
LOC105756001Pyrin and HIN domain-containing protein 1-like. (121 aa)
LOC101349601Myeloid cell nuclear differentiation antigen-like. (219 aa)
LOC101351301Interferon-induced 35 kDa protein. (284 aa)
LOC101360569DCC-interacting protein 13-beta. (597 aa)
LOC101342306Protein LSM14 homolog A. (533 aa)
LOC111819392Killer cell lectin-like receptor subfamily I member 1. (254 aa)
LOC101361497NKG2-A/NKG2-B type II integral membrane protein-like. (187 aa)
LOC101346982YTH domain-containing family protein 3 isoform X1. (672 aa)
LOC101349867NKG2-A/NKG2-B type II integral membrane protein-like. (183 aa)
LOC105757002NKG2-A/NKG2-B type II integral membrane protein-like. (225 aa)
LOC111819362NKG2-A/NKG2-B type II integral membrane protein-like. (189 aa)
LOC101351735NEDD4-binding protein 1 isoform X1. (860 aa)
LOC101344268Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform X2. (652 aa)
LOC101348743Hepatitis A virus cellular receptor 2 isoform X1. (328 aa)
LOC105757003Natural killer cells antigen CD94-like. (149 aa)
LOC111819380NKG2-A/NKG2-B type II integral membrane protein-like isoform X1. (226 aa)
LOC101346289NKG2-A/NKG2-B type II integral membrane protein-like isoform X1. (222 aa)
LOC111819361NKG2-A/NKG2-B type II integral membrane protein-like. (236 aa)
LOC101349863Gamma-interferon-inducible protein 16 isoform X1. (912 aa)
LOC101354659LOW QUALITY PROTEIN: T-cell surface protein tactile-like. (240 aa)
LOC101340311Matrin-3 isoform X1. (892 aa)
LOC101346964Tyrosine-protein phosphatase non-receptor type. (416 aa)
LOC101349348Myeloid cell nuclear differentiation antigen. (438 aa)
LOC101357919Apoptosis-associated speck-like protein containing a CARD. (205 aa)
LOC101355274Toll/interleukin-1 receptor domain-containing adapter protein. (221 aa)
LOC101343892Ubiquitin-like protein ISG15. (162 aa)
LOC101358775Mitochondrial antiviral-signaling protein. (545 aa)
LOC101352321LOW QUALITY PROTEIN: DCC-interacting protein 13-alpha. (625 aa)
LOC101345689Cis-aconitate decarboxylase. (473 aa)
LOC101346715Protein FAM3A. (256 aa)
LOC101343315NKG2-D type II integral membrane protein-like. (220 aa)
LOC101344931Probable ATP-dependent RNA helicase DHX58 isoform X2. (677 aa)
LOC101351297N6-adenosine-methyltransferase catalytic subunit isoform X1; Belongs to the MT-A70-like family. (580 aa)
LOC101357350SLAM family member 8. (296 aa)
LOC101349076Hemopexin. (472 aa)
LOC101350673Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (329 aa)
LOC101352675Ficolin-2. (319 aa)
LOC101355231E3 ubiquitin-protein ligase DCST1. (717 aa)
LOC101360020Double-stranded RNA-specific adenosine deaminase isoform X1. (1171 aa)
LOC101361050Caspase recruitment domain-containing protein 9 isoform X1. (537 aa)
LOC101343385Lymphocyte activation gene 3 protein. (526 aa)
LOC101354375E3 ubiquitin-protein ligase TRIM41 isoform X1. (632 aa)
LOC101348980Killer cell lectin-like receptor subfamily G member 1. (190 aa)
LOC101348209E3 ubiquitin-protein ligase TRIM56. (764 aa)
LOC101354708SH2 domain-containing protein 1B. (131 aa)
LOC101357663Cell adhesion molecule 1 isoform X2. (444 aa)
LOC101356832Cell growth-regulating nucleolar protein. (395 aa)
LOC101345747C-type lectin domain family 12 member B. (276 aa)
LOC101354614Uncharacterized protein CXorf21 homolog. (300 aa)
LOC101360960Otopetrin-1. (593 aa)
LOC101342871Mannan-binding lectin serine protease 2; Belongs to the peptidase S1 family. (687 aa)
LOC101355290Ubiquitin-conjugating enzyme E2 K isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
LOC101352734FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (202 aa)
LOC101357146Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
LOC101349901D(2) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (443 aa)
LOC101348880Interferon regulatory factor 3. (421 aa)
LOC101351430Mannan-binding lectin serine protease 1 isoform X1; Belongs to the peptidase S1 family. (728 aa)
LOC101359826DNA-directed RNA polymerase III subunit RPC4. (398 aa)
LOC101349136Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa)
LOC101342936Interleukin-1 receptor-associated kinase 3. (582 aa)
LOC101359119V-set and immunoglobulin domain-containing protein 4. (399 aa)
LOC101342770Stimulator of interferon genes protein. (387 aa)
LOC101343104Neutrophil cytosol factor 1 isoform X1. (391 aa)
LOC101362039Tubulin--tyrosine ligase-like protein 12. (657 aa)
LOC101343790RAS guanyl-releasing protein 1 isoform X1. (831 aa)
LOC101347430SH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. (128 aa)
LOC101353758RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (534 aa)
LOC101347761Caspase-6 isoform X1; Belongs to the peptidase C14A family. (289 aa)
LOC101360682X-ray repair cross-complementing protein 6 isoform X1. (612 aa)
LOC101348948Signal transducer and activator of transcription. (851 aa)
LOC101348865TRAF-type zinc finger domain-containing protein 1 isoform X1. (559 aa)
LOC101357471Cactin. (708 aa)
LOC101357378Hsp90 co-chaperone Cdc37. (380 aa)
LOC101341330Mitochondrial import receptor subunit TOM70. (609 aa)
LOC101352974Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1580 aa)
LOC1013463931-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1267 aa)
LOC101342084LOW QUALITY PROTEIN: ficolin-3. (294 aa)
LOC101351238Phospholipase A(2). (138 aa)
LOC101345286Mitochondrial ubiquitin ligase activator of NFKB 1. (352 aa)
LOC101361517X-ray repair cross-complementing protein 5 isoform X1. (742 aa)
LOC101340547Cochlin. (549 aa)
LOC101358577DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (316 aa)
LOC101342748Adapter molecule crk isoform X1. (304 aa)
LOC101341906Sushi domain-containing protein 4. (486 aa)
LOC101346733DNA-dependent protein kinase catalytic subunit isoform X1; Belongs to the PI3/PI4-kinase family. (4134 aa)
LOC101344211N-myc-interactor. (312 aa)
LOC101344779Inhibitor of nuclear factor kappa-B kinase subunit epsilon. (720 aa)
LOC101348760Granulins. (595 aa)
LOC101361336DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1173 aa)
LOC101355851Suppressor of cytokine signaling 1. (211 aa)
LOC101343320NLR family CARD domain-containing protein 3 isoform X1. (1065 aa)
LOC101348242Splicing factor, proline- and glutamine-rich isoform X1. (715 aa)
LOC101352861E3 ubiquitin-protein ligase TRIM62. (475 aa)
Your Current Organism:
Trichechus manatus
NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris
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