(27 nodes) Regulation of T-helper cell differentiation network (Trichechus manatus)

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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Predicted Interactions

gene neighborhood

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Your Input:
	LOC101341719	SH2 domain-containing adapter protein B. (506 aa)
	LOC101344202	Roquin-1 isoform X1. (1134 aa)
	LOC101349206	Interleukin-23 subunit alpha isoform X1. (191 aa)
	LOC101350732	NACHT, LRR and PYD domains-containing protein 12 isoform X1. (1055 aa)
	LOC101350478	B-cell lymphoma 6 protein. (706 aa)
	LOC101345231	Tyrosine-protein kinase. (1106 aa)
	LOC101360180	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (174 aa)
	LOC101361466	Interleukin-27 subunit alpha. (237 aa)
	LOC101357170	Zinc finger and BTB domain-containing protein 7B. (536 aa)
	LOC101347481	Mothers against decapentaplegic homolog. (426 aa)
	LOC101354955	Annexin. (133 aa)
	LOC101344675	NF-kappa-B inhibitor delta. (328 aa)
	LOC101348624	Interleukin-18. (201 aa)
	LOC101348056	Suppressor of cytokine signaling 5. (537 aa)
	LOC101354015	Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (447 aa)
	LOC101356545	Roquin-2 isoform X1. (1189 aa)
	LOC101347391	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (537 aa)
	LOC101347120	Transcriptional activator Myb isoform X3. (761 aa)
	LOC101343658	Lysyl oxidase homolog 3. (753 aa)
	LOC101360215	C-C motif chemokine. (116 aa)
	LOC101340620	Endoribonuclease ZC3H12A isoform X1. (612 aa)
	LOC101342230	Tumor necrosis factor ligand superfamily member 18. (181 aa)
	LOC101344861	H2.0-like homeobox protein. (488 aa)
	LOC101361863	Forkhead box protein P3 isoform X1. (429 aa)
	LOC101344129	NF-kappa-B inhibitor zeta isoform X1. (718 aa)
	LOC101346659	T-box transcription factor TBX21. (536 aa)
	LOC101343517	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform X1. (819 aa)

Your Current Organism:

Trichechus manatus

NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101340620	LOC101344129	A0A2Y9DDD1	A0A2Y9DNY2	Endoribonuclease ZC3H12A isoform X1.	NF-kappa-B inhibitor zeta isoform X1.	0.440
LOC101340620	LOC101344202	A0A2Y9DDD1	A0A2Y9QQW7	Endoribonuclease ZC3H12A isoform X1.	Roquin-1 isoform X1.	0.555
LOC101343517	LOC101344129	A0A2Y9DQY7	A0A2Y9DNY2	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform X1.	NF-kappa-B inhibitor zeta isoform X1.	0.422
LOC101344129	LOC101340620	A0A2Y9DNY2	A0A2Y9DDD1	NF-kappa-B inhibitor zeta isoform X1.	Endoribonuclease ZC3H12A isoform X1.	0.440
LOC101344129	LOC101343517	A0A2Y9DNY2	A0A2Y9DQY7	NF-kappa-B inhibitor zeta isoform X1.	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform X1.	0.422
LOC101344202	LOC101340620	A0A2Y9QQW7	A0A2Y9DDD1	Roquin-1 isoform X1.	Endoribonuclease ZC3H12A isoform X1.	0.555
LOC101344202	LOC101356545	A0A2Y9QQW7	A0A2Y9QYZ4	Roquin-1 isoform X1.	Roquin-2 isoform X1.	0.533
LOC101344861	LOC101346659	A0A2Y9DJP0	A0A2Y9DP38	H2.0-like homeobox protein.	T-box transcription factor TBX21.	0.560
LOC101345231	LOC101348056	A0A2Y9DZP7	A0A2Y9RCI0	Tyrosine-protein kinase.	Suppressor of cytokine signaling 5.	0.835
LOC101345231	LOC101360180	A0A2Y9DZP7	A0A2Y9E495	Tyrosine-protein kinase.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	0.974
LOC101346659	LOC101344861	A0A2Y9DP38	A0A2Y9DJP0	T-box transcription factor TBX21.	H2.0-like homeobox protein.	0.560
LOC101346659	LOC101350478	A0A2Y9DP38	A0A2Y9DXA5	T-box transcription factor TBX21.	B-cell lymphoma 6 protein.	0.600
LOC101346659	LOC101354015	A0A2Y9DP38	A0A2Y9R3R7	T-box transcription factor TBX21.	Trans-acting T-cell-specific transcription factor GATA-3 isoform X1.	0.968
LOC101346659	LOC101360180	A0A2Y9DP38	A0A2Y9E495	T-box transcription factor TBX21.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	0.545
LOC101346659	LOC101361863	A0A2Y9DP38	A0A2Y9DLG9	T-box transcription factor TBX21.	Forkhead box protein P3 isoform X1.	0.593
LOC101347120	LOC101354015	A0A2Y9D6Y2	A0A2Y9R3R7	Transcriptional activator Myb isoform X3.	Trans-acting T-cell-specific transcription factor GATA-3 isoform X1.	0.545
LOC101347391	LOC101350732	A0A2Y9QRK2	A0A2Y9DVB7	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	NACHT, LRR and PYD domains-containing protein 12 isoform X1.	0.523
LOC101348056	LOC101345231	A0A2Y9RCI0	A0A2Y9DZP7	Suppressor of cytokine signaling 5.	Tyrosine-protein kinase.	0.835
LOC101348624	LOC101360180	A0A2Y9RMJ7	A0A2Y9E495	Interleukin-18.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	0.467
LOC101349206	LOC101361466	A0A2Y9DSX2	A0A2Y9E5A6	Interleukin-23 subunit alpha isoform X1.	Interleukin-27 subunit alpha.	0.522