(21 nodes) Focal adhesion assembly network (Trichechus manatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101361835	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1. (588 aa)
	LOC101353293	Dual specificity testis-specific protein kinase 2. (573 aa)
	LOC101349912	Rho GTPase-activating protein 6. (780 aa)
	LOC105755961	Stonin-1; Belongs to the Stoned B family. (733 aa)
	LOC101347560	Sorbin and SH3 domain-containing protein 1. (1293 aa)
	LOC101361164	Coronin; Belongs to the WD repeat coronin family. (525 aa)
	LOC101355593	Alpha-actinin-2. (894 aa)
	LOC101346989	Coronin; Belongs to the WD repeat coronin family. (475 aa)
	LOC101352017	Protein RCC2. (525 aa)
	LOC101347007	Apoptosis regulator Bcl-2 isoform X1. (229 aa)
	LOC101354947	Protein-tyrosine kinase 2-beta isoform X3; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
	LOC101347024	Rho-related GTP-binding protein RhoD isoform X1. (210 aa)
	LOC101350996	Alpha-actinin-3. (900 aa)
	LOC101341015	Thy-1 membrane glycoprotein. (161 aa)
	LOC101358537	Thrombospondin type-1 domain-containing protein 1. (853 aa)
	LOC101344350	LIM domain-containing protein ajuba. (548 aa)
	LOC101346946	Breakpoint cluster region protein. (840 aa)
	LOC101352216	Src substrate cortactin. (558 aa)
	LOC101355316	WASP homolog-associated protein with actin, membranes and microtubules. (717 aa)
	LOC101347562	Receptor-type tyrosine-protein phosphatase kappa. (1394 aa)
	LOC101345687	Fermitin family homolog 2. (492 aa)

Your Current Organism:

Trichechus manatus

NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101344350	LOC101345687	A0A2Y9EA57	A0A2Y9QKI3	LIM domain-containing protein ajuba.	Fermitin family homolog 2.	0.412
LOC101345687	LOC101344350	A0A2Y9QKI3	A0A2Y9EA57	Fermitin family homolog 2.	LIM domain-containing protein ajuba.	0.412
LOC101346946	LOC101347024	A0A2Y9G080	A0A2Y9DYP6	Breakpoint cluster region protein.	Rho-related GTP-binding protein RhoD isoform X1.	0.430
LOC101346946	LOC101349912	A0A2Y9G080	A0A2Y9RS53	Breakpoint cluster region protein.	Rho GTPase-activating protein 6.	0.404
LOC101347024	LOC101346946	A0A2Y9DYP6	A0A2Y9G080	Rho-related GTP-binding protein RhoD isoform X1.	Breakpoint cluster region protein.	0.430
LOC101347024	LOC101355316	A0A2Y9DYP6	A0A2Y9QIQ2	Rho-related GTP-binding protein RhoD isoform X1.	WASP homolog-associated protein with actin, membranes and microtubules.	0.547
LOC101349912	LOC101346946	A0A2Y9RS53	A0A2Y9G080	Rho GTPase-activating protein 6.	Breakpoint cluster region protein.	0.404
LOC101350996	LOC101355593	A0A2Y9DZZ3	A0A2Y9DDZ1	Alpha-actinin-3.	Alpha-actinin-2.	0.946
LOC101352216	LOC101354947	A0A2Y9G1M9	A0A2Y9DX75	Src substrate cortactin.	Protein-tyrosine kinase 2-beta isoform X3; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.749
LOC101352216	LOC101355316	A0A2Y9G1M9	A0A2Y9QIQ2	Src substrate cortactin.	WASP homolog-associated protein with actin, membranes and microtubules.	0.928
LOC101354947	LOC101352216	A0A2Y9DX75	A0A2Y9G1M9	Protein-tyrosine kinase 2-beta isoform X3; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Src substrate cortactin.	0.749
LOC101355316	LOC101347024	A0A2Y9QIQ2	A0A2Y9DYP6	WASP homolog-associated protein with actin, membranes and microtubules.	Rho-related GTP-binding protein RhoD isoform X1.	0.547
LOC101355316	LOC101352216	A0A2Y9QIQ2	A0A2Y9G1M9	WASP homolog-associated protein with actin, membranes and microtubules.	Src substrate cortactin.	0.928
LOC101355593	LOC101350996	A0A2Y9DDZ1	A0A2Y9DZZ3	Alpha-actinin-2.	Alpha-actinin-3.	0.946