STRINGSTRING
LOC101344202 LOC101344202 LOC101349613 LOC101349613 LOC101347391 LOC101347391 LOC101352491 LOC101352491 LOC101354918 LOC101354918 LOC101357366 LOC101357366 LOC101357703 LOC101357703 LOC101347585 LOC101347585 LOC101357695 LOC101357695 LOC101344208 LOC101344208 LOC101346475 LOC101346475 LOC101357884 LOC101357884 LOC101356880 LOC101356880 LOC101361773 LOC101361773 LOC101356455 LOC101356455 LOC101340536 LOC101340536 LOC101357635 LOC101357635 LOC101342846 LOC101342846 LOC101343347 LOC101343347 LOC101353752 LOC101353752 LOC101346575 LOC101346575 LOC101344210 LOC101344210 LOC101359279 LOC101359279 LOC111820939 LOC111820939 LOC101347632 LOC101347632 LOC101350902 LOC101350902 LOC101359471 LOC101359471 LOC101356005 LOC101356005 LOC101355872 LOC101355872 LOC101356219 LOC101356219 LOC101355538 LOC101355538 LOC101352541 LOC101352541 LOC101358598 LOC101358598 LOC101342008 LOC101342008 LOC101349653 LOC101349653 LOC101345331 LOC101345331 LOC101341175 LOC101341175 LOC101359570 LOC101359570 LOC101351266 LOC101351266 LOC101357914 LOC101357914 LOC101348111 LOC101348111 LOC101356572 LOC101356572 LOC101361885 LOC101361885 LOC101355206 LOC101355206 LOC111821652 LOC111821652 LOC101348624 LOC101348624 LOC101357071 LOC101357071 LOC101360445 LOC101360445 LOC101351806 LOC101351806 LOC101358693 LOC101358693 LOC101351984 LOC101351984 LOC101358096 LOC101358096 LOC101359510 LOC101359510 LOC101345594 LOC101345594 LOC101345060 LOC101345060 LOC101346535 LOC101346535 LOC101352502 LOC101352502 IL1B IL1B LOC101355495 LOC101355495 LOC101356504 LOC101356504 LOC101353271 LOC101353271 LOC101342543 LOC101342543 LOC101359591 LOC101359591 LOC101355751 LOC101355751 LOC101350431 LOC101350431 LOC101355323 LOC101355323 LOC101354148 LOC101354148 LOC101356519 LOC101356519 LOC101348743 LOC101348743 LOC101343153 LOC101343153 LOC101358198 LOC101358198 LOC101357934 LOC101357934 LOC101357192 LOC101357192 LOC101342469 LOC101342469 LOC105756374 LOC105756374 LOC101357919 LOC101357919 LOC101355274 LOC101355274 LOC101342172 LOC101342172 LOC101354955 LOC101354955 LOC101356114 LOC101356114 LOC101346404 LOC101346404 LOC101354153 LOC101354153 LOC101343160 LOC101343160 LOC101346112 LOC101346112 LOC101343407 LOC101343407 LOC101360729 LOC101360729 LOC101342886 LOC101342886 LOC101357170 LOC101357170 LOC101352067 LOC101352067 LOC101347965 LOC101347965 LOC101350161 LOC101350161 LOC101361969 LOC101361969 LOC101361466 LOC101361466 LOC101360180 LOC101360180 LOC101340854 LOC101340854 LOC101346426 LOC101346426 LOC101344982 LOC101344982 LOC101341859 LOC101341859 LOC101341683 LOC101341683 LOC101343284 LOC101343284 LOC101356828 LOC101356828 LOC101356065 LOC101356065 LOC101355632 LOC101355632 LOC101341939 LOC101341939 LOC101345231 LOC101345231 LOC101354858 LOC101354858 LOC101352734 LOC101352734 LOC101345307 LOC101345307 LOC101357146 LOC101357146 LOC101341346 LOC101341346 LOC101350478 LOC101350478 LOC101340999 LOC101340999 LOC101341848 LOC101341848 LOC101359119 LOC101359119 LOC101351869 LOC101351869 LOC101360596 LOC101360596 LOC101355115 LOC101355115 LOC101341589 LOC101341589 LOC101354525 LOC101354525 LOC101341665 LOC101341665 LOC101353064 LOC101353064 LOC101349206 LOC101349206 LOC101360683 LOC101360683 LOC101352896 LOC101352896 LOC101347007 LOC101347007 LOC101349550 LOC101349550 LOC101350064 LOC101350064 LOC101343092 LOC101343092 LOC101345632 LOC101345632 LOC101351858 LOC101351858 LOC101357885 LOC101357885 LOC101356636 LOC101356636 LOC101341326 LOC101341326 LOC101351590 LOC101351590 LOC101354258 LOC101354258 LOC101350972 LOC101350972 LOC101361863 LOC101361863 LOC101348175 LOC101348175 LOC101344376 LOC101344376 LOC101342743 LOC101342743 LOC101355085 LOC101355085 LOC101359961 LOC101359961 LOC101361934 LOC101361934 LOC101353037 LOC101353037 LOC101351744 LOC101351744 LOC101352610 LOC101352610 LOC101342230 LOC101342230 LOC101360215 LOC101360215 LOC101343839 LOC101343839 LOC101357435 LOC101357435 LOC101358553 LOC101358553 LOC101347392 LOC101347392 LOC101344352 LOC101344352 LOC101346545 LOC101346545 LOC101358640 LOC101358640 LOC101359592 LOC101359592 LOC101347968 LOC101347968 LOC101355304 LOC101355304 LOC101351541 LOC101351541 LOC101351897 LOC101351897 LOC101347063 LOC101347063 LOC101348230 LOC101348230 LOC101347479 LOC101347479 LOC101350772 LOC101350772
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101344202Roquin-1 isoform X1. (1134 aa)
LOC101349613T-lymphocyte activation antigen CD80 isoform X1. (344 aa)
LOC101347391Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (537 aa)
LOC101352491Interleukin-12 receptor subunit beta-2. (864 aa)
LOC101354918Tyrosine-protein kinase. (1106 aa)
LOC101357366CMRF35-like molecule 8 isoform X1. (377 aa)
LOC101357703Transferrin receptor protein 1 isoform X1. (834 aa)
LOC101347585T-lymphocyte activation antigen CD86 isoform X1. (311 aa)
LOC101357695Amine oxidase. (518 aa)
LOC101344208Glycerol-3-phosphate acyltransferase 1, mitochondrial. (869 aa)
LOC101346475Myocyte-specific enhancer factor 2C isoform X1. (483 aa)
LOC101357884Tumor necrosis factor receptor superfamily member 1B isoform X1. (458 aa)
LOC101356880Tyrosine-protein kinase. (686 aa)
LOC101361773Insulin-like growth factor-binding protein 2. (159 aa)
LOC101356455Programmed cell death 1 ligand 2 isoform X1. (286 aa)
LOC101340536Nck-associated protein 1-like isoform X1. (1138 aa)
LOC101357635Tyrosine-protein kinase. (1183 aa)
LOC101342846Glomulin isoform X1. (599 aa)
LOC101343347Transmembrane protein 131-like isoform X1. (1638 aa)
LOC101353752Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (238 aa)
LOC101346575Phospholipase A(2). (145 aa)
LOC101344210Receptor-type tyrosine-protein phosphatase C isoform X1. (1305 aa)
LOC101359279E3 ubiquitin-protein ligase MARCH7 isoform X1. (736 aa)
LOC111820939C-type lectin domain family 4 member G. (179 aa)
LOC101347632Tyrosine-protein kinase. (617 aa)
LOC101350902SAM and SH3 domain-containing protein 3 isoform X1. (429 aa)
LOC101359471Tumor necrosis factor receptor superfamily member 13C. (350 aa)
LOC101356005Cytoplasmic protein. (380 aa)
LOC101355872Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (720 aa)
LOC101356219Zinc transporter ZIP10 isoform X1. (843 aa)
LOC101355538Interleukin-20 receptor subunit beta. (263 aa)
LOC101352541LOW QUALITY PROTEIN: transcription factor E2-alpha. (716 aa)
LOC101358598NEDD4 family-interacting protein 1 isoform X1. (224 aa)
LOC101342008Cyclin-dependent kinase inhibitor 1 isoform X1. (189 aa)
LOC101349653Coiled-coil domain-containing protein 88B. (1477 aa)
LOC101345331TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
LOC101341175V-type immunoglobulin domain-containing suppressor of T-cell activation isoform X1. (409 aa)
LOC101359570Tumor necrosis factor receptor superfamily member 14 isoform X1. (293 aa)
LOC101351266Interleukin-12 receptor subunit beta-1. (694 aa)
LOC101357914RAS protein activator like-3. (1056 aa)
LOC101348111Indoleamine 2,3-dioxygenase 1. (407 aa)
LOC101356572G-protein coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (361 aa)
LOC101361885Tyrosine-protein kinase. (508 aa)
LOC101355206Serine-protein kinase ATM isoform X1. (2331 aa)
LOC111821652Serine-protein kinase ATM-like; Belongs to the PI3/PI4-kinase family. (700 aa)
LOC101348624Interleukin-18. (201 aa)
LOC101357071Galectin. (356 aa)
LOC101360445Interleukin; Belongs to the IL-15/IL-21 family. (178 aa)
LOC101351806Tyrosine-protein kinase. (685 aa)
LOC101358693HLA class II histocompatibility antigen gamma chain isoform X3. (267 aa)
LOC101351984Adenosine deaminase-like. (250 aa)
LOC101358096Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (651 aa)
LOC101359510T-cell differentiation antigen CD6. (670 aa)
LOC101345594Tumor necrosis factor receptor superfamily member 5 isoform X1. (283 aa)
LOC101345060Interleukin-7 isoform X1. (186 aa)
LOC101346535TYRO protein tyrosine kinase-binding protein. (118 aa)
LOC101352502Adenosine deaminase. (396 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (262 aa)
LOC101355495Cytotoxic and regulatory T-cell molecule. (374 aa)
LOC101356504Protein scribble homolog isoform X1. (1638 aa)
LOC101353271Guanine nucleotide exchange factor VAV3 isoform X1. (850 aa)
LOC101342543Transforming growth factor beta; Belongs to the TGF-beta family. (392 aa)
LOC101359591LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase SH3RF1. (888 aa)
LOC101355751Nuclear factor of activated T-cells, cytoplasmic 2 isoform X1. (930 aa)
LOC101350431Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (197 aa)
LOC101355323LOW QUALITY PROTEIN: receptor-interacting serine/threonine-protein kinase 3. (551 aa)
LOC101354148Signal transducer and activator of transcription 5B. (581 aa)
LOC101356519E3 ubiquitin-protein ligase. (861 aa)
LOC101348743Hepatitis A virus cellular receptor 2 isoform X1. (328 aa)
LOC101343153Deoxyhypusine synthase. (337 aa)
LOC101358198Tetraspanin. (165 aa)
LOC101357934Tetraspanin-32 isoform X1. (385 aa)
LOC101357192Leukocyte-specific transcript 1 protein isoform X1. (124 aa)
LOC101342469L-amino-acid oxidase-like. (526 aa)
LOC105756374LOW QUALITY PROTEIN: HERV-H LTR-associating protein 2. (344 aa)
LOC101357919Apoptosis-associated speck-like protein containing a CARD. (205 aa)
LOC101355274Toll/interleukin-1 receptor domain-containing adapter protein. (221 aa)
LOC101342172LOW QUALITY PROTEIN: CD320 antigen. (258 aa)
LOC101354955Annexin. (133 aa)
LOC101356114CD276 antigen. (302 aa)
LOC101346404Polycomb complex protein BMI-1. (326 aa)
LOC101354153Advanced glycosylation end product-specific receptor isoform X1. (418 aa)
LOC101343160Allograft inflammatory factor 1 isoform X1. (147 aa)
LOC101346112ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2. (349 aa)
LOC101343407Signal transducer and activator of transcription. (799 aa)
LOC101360729Signaling lymphocytic activation molecule. (323 aa)
LOC101342886C-Jun-amino-terminal kinase-interacting protein 1. (706 aa)
LOC101357170Zinc finger and BTB domain-containing protein 7B. (536 aa)
LOC101352067Galectin. (139 aa)
LOC101347965B-cell receptor CD22 isoform X1. (838 aa)
LOC101350161Leucine-rich repeat-containing protein 1 isoform X1. (524 aa)
LOC101361969Coronin; Belongs to the WD repeat coronin family. (461 aa)
LOC101361466Interleukin-27 subunit alpha. (237 aa)
LOC101360180Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (174 aa)
LOC101340854Caspase recruitment domain-containing protein 11. (1155 aa)
LOC101346426Zona pellucida sperm-binding protein 3. (431 aa)
LOC101344982Twisted gastrulation protein homolog 1. (223 aa)
LOC101341859Mitotic spindle assembly checkpoint protein MAD1. (717 aa)
LOC101341683Interleukin; Belongs to the IL-15/IL-21 family. (210 aa)
LOC101343284ATPase family AAA domain-containing protein 5. (1855 aa)
LOC101356828Tumor necrosis factor receptor superfamily member 9. (260 aa)
LOC101356065Interferon regulatory factor. (326 aa)
LOC101355632Tumor necrosis factor receptor superfamily member 4. (276 aa)
LOC101341939PRKC apoptosis WT1 regulator protein. (338 aa)
LOC101345231Tyrosine-protein kinase. (1106 aa)
LOC101354858High affinity cationic amino acid transporter 1. (629 aa)
LOC101352734FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (202 aa)
LOC101345307Cardiotrophin-like cytokine factor 1. (225 aa)
LOC101357146Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
LOC101341346Disks large homolog 5; Belongs to the MAGUK family. (1921 aa)
LOC101350478B-cell lymphoma 6 protein. (706 aa)
LOC101340999Tumor necrosis factor ligand superfamily member 13B; Belongs to the tumor necrosis factor family. (288 aa)
LOC101341848Leucine-rich repeat-containing protein 32. (658 aa)
LOC101359119V-set and immunoglobulin domain-containing protein 4. (399 aa)
LOC101351869Amine oxidase. (560 aa)
LOC10136059640S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa)
LOC101355115Cytoplasmic protein. (377 aa)
LOC101341589Marginal zone B- and B1-cell-specific protein. (189 aa)
LOC101354525CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
LOC101341665Tumor necrosis factor receptor superfamily member 13B. (300 aa)
LOC101353064Interleukin-6 receptor subunit beta isoform X1. (919 aa)
LOC101349206Interleukin-23 subunit alpha isoform X1. (191 aa)
LOC101360683V-set domain-containing T-cell activation inhibitor 1. (215 aa)
LOC101352896ephrin-B1; Belongs to the ephrin family. (347 aa)
LOC101347007Apoptosis regulator Bcl-2 isoform X1. (229 aa)
LOC101349550Tumor necrosis factor receptor superfamily member 21. (657 aa)
LOC101350064LOW QUALITY PROTEIN: tumor necrosis factor ligand superfamily member 9; Belongs to the tumor necrosis factor family. (360 aa)
LOC101343092T-cell-specific surface glycoprotein CD28 isoform X1. (256 aa)
LOC101345632E3 ubiquitin-protein ligase CBL-B. (983 aa)
LOC101351858Cytotoxic T-lymphocyte protein 4 isoform X1. (222 aa)
LOC101357885Transmembrane glycoprotein NMB. (556 aa)
LOC101356636Zinc finger protein Aiolos isoform X1. (509 aa)
LOC101341326Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (314 aa)
LOC101351590Interleukin-6. (237 aa)
LOC101354258TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
LOC101350972Phospholipase A(2). (210 aa)
LOC101361863Forkhead box protein P3 isoform X1. (429 aa)
LOC101348175Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
LOC101344376Ras association domain-containing protein 5 isoform X1. (416 aa)
LOC101342743Interleukin-10. (178 aa)
LOC101355085Forkhead box protein J1. (418 aa)
LOC101359961Programmed cell death 1 ligand 1 isoform X1. (288 aa)
LOC101361934Insulin-like growth factor I isoform X1. (189 aa)
LOC101353037Tyrosine-protein kinase. (512 aa)
LOC101351744LOW QUALITY PROTEIN: sonic hedgehog protein. (272 aa)
LOC101352610Tumor necrosis factor ligand superfamily member 4; Belongs to the tumor necrosis factor family. (183 aa)
LOC101342230Tumor necrosis factor ligand superfamily member 18. (181 aa)
LOC101360215C-C motif chemokine. (116 aa)
LOC101343839Thrombopoietin receptor isoform X1. (634 aa)
LOC101357435Arginase. (354 aa)
LOC101358553Galectin. (258 aa)
LOC101347392Son of sevenless homolog 2 isoform X1. (1328 aa)
LOC101344352Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa)
LOC101346545Zinc finger protein 335. (1344 aa)
LOC101358640CCAAT/enhancer-binding protein. (343 aa)
LOC101359592Son of sevenless homolog 1 isoform X1. (1333 aa)
LOC101347968E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
LOC101355304Arginase. (330 aa)
LOC101351541Toll-like receptor 9 isoform X1. (1323 aa)
LOC101351897Catenin beta-1. (781 aa)
LOC101347063Spectrin alpha chain, erythrocytic 1. (2374 aa)
LOC101348230Interleukin-27 receptor subunit alpha isoform X1. (635 aa)
LOC101347479Serine/threonine-protein kinase N1. (951 aa)
LOC101350772Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1. (1354 aa)
Your Current Organism:
Trichechus manatus
NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris
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