STRINGSTRING
LOC101360145 LOC101360145 LOC101341527 LOC101341527 LOC101348223 LOC101348223 LOC101347308 LOC101347308 LOC101351391 LOC101351391 LOC101345598 LOC101345598 LOC101351204 LOC101351204 LOC101350271 LOC101350271 LOC101353981 LOC101353981 LOC101358906 LOC101358906 LOC101355840 LOC101355840 LOC101359953 LOC101359953 LOC101343863 LOC101343863 LOC101354258 LOC101354258 LOC101348356 LOC101348356 LOC101348173 LOC101348173 LOC101361168 LOC101361168 LOC101343674 LOC101343674 LOC101349256 LOC101349256 LOC101340315 LOC101340315 LOC101358099 LOC101358099 LOC101342441 LOC101342441 LOC101344623 LOC101344623 LOC101342744 LOC101342744 LOC101350268 LOC101350268 LOC101347481 LOC101347481 LOC101356927 LOC101356927 LOC101350503 LOC101350503 LOC101343630 LOC101343630 LOC101352045 LOC101352045 LOC101342863 LOC101342863 LOC101354200 LOC101354200 LOC101358165 LOC101358165 LOC101340313 LOC101340313 LOC101344397 LOC101344397 LOC101344637 LOC101344637 LOC101344225 LOC101344225 LOC101352539 LOC101352539 LOC101341075 LOC101341075 LOC101344634 LOC101344634 LOC101353057 LOC101353057 LOC101348816 LOC101348816 LOC101343375 LOC101343375 LOC101352224 LOC101352224 LOC101361134 LOC101361134 LOC101350220 LOC101350220 LOC101358763 LOC101358763 LOC101351852 LOC101351852 LOC101357210 LOC101357210
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101360145Short-chain dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
LOC101341527Cbp/p300-interacting transactivator 2. (270 aa)
LOC101348223Protein CYR61. (382 aa)
LOC101347308Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
LOC101351391Bone morphogenetic protein 7. (431 aa)
LOC101345598Zinc finger protein ZFPM2 isoform X1. (1151 aa)
LOC101351204Homeobox protein Nkx-2.5. (323 aa)
LOC101350271Heart- and neural crest derivatives-expressed protein 1. (219 aa)
LOC101353981Roundabout homolog 1 isoform X1. (1651 aa)
LOC101358906LOW QUALITY PROTEIN: slit homolog 3 protein. (1525 aa)
LOC101355840Hairy/enhancer-of-split related with YRPW motif-like protein. (328 aa)
LOC101359953Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (499 aa)
LOC101343863Slit homolog 2 protein isoform X1. (1534 aa)
LOC101354258TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
LOC101348356Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1037 aa)
LOC101348173LOW QUALITY PROTEIN: endoglin. (765 aa)
LOC101361168chromodomain-helicase-DNA-binding protein 7. (2924 aa)
LOC101343674Roundabout homolog 2. (1451 aa)
LOC101349256Protein salvador homolog 1 isoform X1. (389 aa)
LOC101340315Transcription factor GATA-4 isoform X1. (443 aa)
LOC101358099Transcription factor GATA-6. (481 aa)
LOC101342441Hairy/enhancer-of-split related with YRPW motif protein 1 isoform X1. (307 aa)
LOC101344623Mothers against decapentaplegic homolog. (497 aa)
LOC101342744Low-density lipoprotein receptor-related protein 2. (4634 aa)
LOC101350268T-box transcription factor TBX1. (449 aa)
LOC101347481Mothers against decapentaplegic homolog. (426 aa)
LOC101356927Apelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)
LOC101350503Prospero homeobox protein 1. (736 aa)
LOC101343630T-box transcription factor TBX20. (449 aa)
LOC101352045Fibroblast growth factor receptor-like 1. (494 aa)
LOC101342863Hairy/enhancer-of-split related with YRPW motif protein 2. (336 aa)
LOC101354200Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
LOC101358165Smoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (749 aa)
LOC101340313Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
LOC101344397semaphorin-3C; Belongs to the semaphorin family. (751 aa)
LOC101344637T-box transcription factor TBX5 isoform X1. (518 aa)
LOC101344225T-box transcription factor TBX3 isoform X1. (745 aa)
LOC101352539Neuropilin; Belongs to the neuropilin family. (926 aa)
LOC101341075Meckel syndrome type 1 protein isoform X1. (558 aa)
LOC101344634Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
LOC101353057T-box transcription factor TBX2. (589 aa)
LOC101348816Neurogenic locus notch homolog protein 1. (2569 aa)
LOC101343375Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
LOC101352224Bone morphogenetic protein 5 isoform X1. (455 aa)
LOC101361134Neuropilin; Belongs to the neuropilin family. (838 aa)
LOC101350220Histone-lysine N-methyltransferase NSD2. (1387 aa)
LOC101358763Mothers against decapentaplegic homolog. (552 aa)
LOC101351852Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (392 aa)
LOC101357210Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (541 aa)
Your Current Organism:
Trichechus manatus
NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.