(38 nodes) Positive regulation of wound healing network (Trichechus manatus)

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second shell of interactors

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	LOC101355221	Discoidin domain-containing receptor 2. (820 aa)
	LOC101343808	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
	LOC101342229	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 isoform X1. (1850 aa)
	LOC101353039	WNT1-inducible-signaling pathway protein 1 isoform X1. (367 aa)
	LOC101356295	KN motif and ankyrin repeat domain-containing protein 1 isoform X2. (1202 aa)
	LOC101347994	Beta-2-glycoprotein 1. (350 aa)
	LOC101358047	Proteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
	LOC101340451	Alpha-2-antiplasmin; Belongs to the serpin family. (485 aa)
	LOC101350804	Carboxypeptidase B2-like. (412 aa)
	LOC101343093	Thromboxane A2 receptor; Belongs to the G-protein coupled receptor 1 family. (343 aa)
	LOC101343097	CMP-N-acetylneuraminate-beta-galactosamide- alpha-2,3-sialyltransferase 4 isoform X1; Belongs to the glycosyltransferase 29 family. (333 aa)
	LOC101356645	LOW QUALITY PROTEIN: dual oxidase 1. (1330 aa)
	LOC101345381	LOW QUALITY PROTEIN: dual oxidase 2. (1560 aa)
	LOC101340309	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
	LOC101344556	Proheparin-binding EGF-like growth factor. (208 aa)
	LOC101344047	Thrombospondin-1. (1170 aa)
	LOC101340566	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
	LOC101349039	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
	LOC101351257	Fermitin family homolog 1. (676 aa)
	LOC101352912	Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (207 aa)
	LOC101360881	Integrin beta; Belongs to the integrin beta chain family. (832 aa)
	LOC101352235	EMILIN-2. (950 aa)
	LOC101350094	C-type lectin domain family 7 member A isoform X1. (249 aa)
	LOC101358254	Anoctamin. (926 aa)
	LOC101351714	Focal adhesion kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
	LOC101356737	Dematin isoform X1. (402 aa)
	LOC101352051	Insulin-like 3. (97 aa)
	LOC101346584	Bis(5'-adenosyl)-triphosphatase ENPP4 isoform X1. (471 aa)
	LOC101351060	Carboxypeptidase B2. (412 aa)
	LOC101356462	Nuclear factor erythroid 2-related factor 2 isoform X1. (622 aa)
	LOC101359414	SPARC-related modular calcium-binding protein 2. (540 aa)
	LOC101345687	Fermitin family homolog 2. (492 aa)
	LOC101354466	LOW QUALITY PROTEIN: X-box-binding protein 1. (386 aa)
	LOC101354955	Annexin. (133 aa)
	LOC101360212	Heparanase. (540 aa)
	LOC101355921	Ras-responsive element-binding protein 1. (1741 aa)
	LOC101347713	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (621 aa)
	LOC101348466	Plasminogen activator inhibitor 1; Belongs to the serpin family. (400 aa)

Your Current Organism:

Trichechus manatus

NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101340309	LOC101340566	A0A2Y9DTC0	A0A2Y9DUK4	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.655
LOC101340309	LOC101349039	A0A2Y9DTC0	A0A2Y9DXA2	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.771
LOC101340451	LOC101347713	A0A2Y9DKF1	A0A2Y9E608	Alpha-2-antiplasmin; Belongs to the serpin family.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.777
LOC101340451	LOC101347994	A0A2Y9DKF1	A0A2Y9DGN8	Alpha-2-antiplasmin; Belongs to the serpin family.	Beta-2-glycoprotein 1.	0.606
LOC101340451	LOC101350804	A0A2Y9DKF1	A0A2Y9DLB9	Alpha-2-antiplasmin; Belongs to the serpin family.	Carboxypeptidase B2-like.	0.507
LOC101340451	LOC101351060	A0A2Y9DKF1	A0A2Y9R1A8	Alpha-2-antiplasmin; Belongs to the serpin family.	Carboxypeptidase B2.	0.507
LOC101340451	LOC101354955	A0A2Y9DKF1	A0A2Y9FYZ0	Alpha-2-antiplasmin; Belongs to the serpin family.	Annexin.	0.404
LOC101340566	LOC101340309	A0A2Y9DUK4	A0A2Y9DTC0	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.655
LOC101340566	LOC101349039	A0A2Y9DUK4	A0A2Y9DXA2	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.771
LOC101344047	LOC101348466	A0A2Y9DUD7	A0A2Y9E5Y9	Thrombospondin-1.	Plasminogen activator inhibitor 1; Belongs to the serpin family.	0.500
LOC101344047	LOC101351714	A0A2Y9DUD7	A0A2Y9RQW3	Thrombospondin-1.	Focal adhesion kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.674
LOC101344047	LOC101360881	A0A2Y9DUD7	A0A2Y9S096	Thrombospondin-1.	Integrin beta; Belongs to the integrin beta chain family.	0.976
LOC101345381	LOC101356645	A0A2Y9DT96	A0A2Y9DTB0	LOW QUALITY PROTEIN: dual oxidase 2.	LOW QUALITY PROTEIN: dual oxidase 1.	0.901
LOC101345687	LOC101360881	A0A2Y9QKI3	A0A2Y9S096	Fermitin family homolog 2.	Integrin beta; Belongs to the integrin beta chain family.	0.694
LOC101347713	LOC101340451	A0A2Y9E608	A0A2Y9DKF1	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Alpha-2-antiplasmin; Belongs to the serpin family.	0.777
LOC101347713	LOC101347994	A0A2Y9E608	A0A2Y9DGN8	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Beta-2-glycoprotein 1.	0.893
LOC101347713	LOC101348466	A0A2Y9E608	A0A2Y9E5Y9	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Plasminogen activator inhibitor 1; Belongs to the serpin family.	0.461
LOC101347713	LOC101350804	A0A2Y9E608	A0A2Y9DLB9	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Carboxypeptidase B2-like.	0.959
LOC101347713	LOC101351060	A0A2Y9E608	A0A2Y9R1A8	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Carboxypeptidase B2.	0.959
LOC101347713	LOC101354955	A0A2Y9E608	A0A2Y9FYZ0	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Annexin.	0.419