51 items (Trichechus manatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101357807	Serine/threonine-protein kinase N2 isoform X1. (981 aa)
	LOC101348845	Microtubule-associated serine/threonine-protein kinase 4 isoform X1. (2623 aa)
	LOC101344716	Ribosomal protein S6 kinase. (770 aa)
	LOC101357816	Myotonin-protein kinase isoform X1. (628 aa)
	LOC101341336	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (465 aa)
	LOC101350197	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (393 aa)
	LOC101343492	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (490 aa)
	LOC101350552	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (426 aa)
	LOC101356212	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1766 aa)
	LOC101350269	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (701 aa)
	LOC101345959	Rho-associated protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1405 aa)
	LOC101355651	Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa)
	LOC101347479	Serine/threonine-protein kinase N1. (951 aa)
	LOC101355872	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (720 aa)
	LOC101349401	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (470 aa)
	LOC101346329	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (686 aa)
	LOC101352076	cGMP-dependent protein kinase 1. (506 aa)
	LOC101344061	Microtubule-associated serine/threonine-protein kinase 3. (1322 aa)
	LOC101346076	cGMP-dependent protein kinase. (762 aa)
	LOC101343202	LOW QUALITY PROTEIN: serine/threonine-protein kinase MRCK gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1549 aa)
	LOC101341711	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (601 aa)
	LOC101340600	Ribosomal protein S6 kinase. (733 aa)
	LOC101353960	Serine/threonine-protein kinase LATS1 isoform X1. (1133 aa)
	LOC101349244	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (445 aa)
	LOC101342638	cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (398 aa)
	LOC101351547	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (565 aa)
	LOC101352863	Microtubule-associated serine/threonine-protein kinase 2. (1682 aa)
	LOC101348995	cAMP-dependent protein kinase catalytic subunit alpha. (293 aa)
	LOC101340565	Serine/threonine-protein kinase greatwall. (877 aa)
	LOC101356099	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
	LOC101355247	Microtubule-associated serine/threonine-protein kinase 1. (1570 aa)
	LOC101344175	Serine/threonine-protein kinase LATS2. (1111 aa)
	LOC101357163	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (688 aa)
	LOC101350086	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
	LOC101355990	cAMP-dependent protein kinase catalytic subunit PRKX isoform X1; Belongs to the protein kinase superfamily. (353 aa)
	LOC101343459	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (553 aa)
	LOC101349045	Ribosomal protein S6 kinase. (771 aa)
	LOC101354778	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (597 aa)
	LOC101343535	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (482 aa)
	LOC101352388	Ribosomal protein S6 kinase. (740 aa)
	LOC101349247	Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
	LOC101357765	Serine/threonine-protein kinase Sgk2; Belongs to the protein kinase superfamily. (367 aa)
	LOC101351254	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
	LOC101343514	Ribosomal protein S6 kinase. (747 aa)
	LOC101360937	Citron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2069 aa)
	LOC101354510	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
	LOC101360493	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	LOC101346998	Serine/threonine-protein kinase MRCK beta; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1712 aa)
	LOC101358750	Ribosomal protein S6 kinase. (801 aa)
	LOC101354923	Serine/threonine-protein kinase N3 isoform X1. (889 aa)
	LOC101356454	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)

Your Current Organism:

Trichechus manatus

NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101340600	LOC101343514	A0A2Y9D6P4	A0A2Y9DQR6	Ribosomal protein S6 kinase.	Ribosomal protein S6 kinase.	0.548
LOC101340600	LOC101344716	A0A2Y9D6P4	A0A2Y9R0F7	Ribosomal protein S6 kinase.	Ribosomal protein S6 kinase.	0.732
LOC101340600	LOC101352388	A0A2Y9D6P4	A0A2Y9DX92	Ribosomal protein S6 kinase.	Ribosomal protein S6 kinase.	0.690
LOC101342638	LOC101343535	A0A2Y9D7C8	A0A2Y9DYE6	cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily.	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	0.928
LOC101342638	LOC101346076	A0A2Y9D7C8	A0A2Y9RP92	cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily.	cGMP-dependent protein kinase.	0.553
LOC101342638	LOC101348995	A0A2Y9D7C8	A0A2Y9QFS5	cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily.	cAMP-dependent protein kinase catalytic subunit alpha.	0.900
LOC101342638	LOC101352076	A0A2Y9D7C8	A0A2Y9RJE0	cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily.	cGMP-dependent protein kinase 1.	0.562
LOC101342638	LOC101354510	A0A2Y9D7C8	A0A2Y9DNR4	cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily.	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	0.928
LOC101343459	LOC101351547	A0A2Y9E109	A0A2Y9D7J3	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.904
LOC101343492	LOC101349244	A0A2Y9QW41	A0A2Y9D6Y8	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.907
LOC101343492	LOC101350197	A0A2Y9QW41	A0A2Y9QX25	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.454
LOC101343492	LOC101356099	A0A2Y9QW41	A0A2Y9ED32	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.455
LOC101343492	LOC101357765	A0A2Y9QW41	A0A2Y9D9B2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Serine/threonine-protein kinase Sgk2; Belongs to the protein kinase superfamily.	0.908
LOC101343492	LOC101360493	A0A2Y9QW41	A0A2Y9DMB0	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.456
LOC101343514	LOC101340600	A0A2Y9DQR6	A0A2Y9D6P4	Ribosomal protein S6 kinase.	Ribosomal protein S6 kinase.	0.548
LOC101343514	LOC101344716	A0A2Y9DQR6	A0A2Y9R0F7	Ribosomal protein S6 kinase.	Ribosomal protein S6 kinase.	0.423
LOC101343535	LOC101342638	A0A2Y9DYE6	A0A2Y9D7C8	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily.	0.928
LOC101343535	LOC101348995	A0A2Y9DYE6	A0A2Y9QFS5	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	cAMP-dependent protein kinase catalytic subunit alpha.	0.927
LOC101343535	LOC101350197	A0A2Y9DYE6	A0A2Y9QX25	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.957
LOC101343535	LOC101354510	A0A2Y9DYE6	A0A2Y9DNR4	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	0.917