STRINGSTRING
LOC101349393 LOC101349393 LOC101356250 LOC101356250 LOC101356564 LOC101356564 LOC101347007 LOC101347007 LOC101345213 LOC101345213 LOC101357722 LOC101357722 LOC101349204 LOC101349204 LOC101341837 LOC101341837 LOC101344302 LOC101344302 LOC101359891 LOC101359891 LOC101340903 LOC101340903 LOC101360930 LOC101360930 LOC101343776 LOC101343776 LOC101354173 LOC101354173 LOC101343175 LOC101343175 LOC101352493 LOC101352493 LOC101344706 LOC101344706 LOC101346361 LOC101346361 LOC101351914 LOC101351914 LOC101352499 LOC101352499 LOC101354307 LOC101354307 LOC101340375 LOC101340375 LOC101341834 LOC101341834 LOC101346298 LOC101346298 LOC101347432 LOC101347432 LOC101355103 LOC101355103 LOC101346318 LOC101346318 LOC101350319 LOC101350319 LOC101343394 LOC101343394 LOC101351864 LOC101351864 LOC101358526 LOC101358526 LOC101352047 LOC101352047 LOC111822341 LOC111822341 LOC101342121 LOC101342121 LOC101356396 LOC101356396 LOC101345470 LOC101345470 LOC101359074 LOC101359074 LOC101341801 LOC101341801 LOC101341201 LOC101341201 LOC101355182 LOC101355182 LOC101357052 LOC101357052 LOC101358941 LOC101358941 LOC101354940 LOC101354940 LOC105756562 LOC105756562 LOC101350286 LOC101350286 LOC101355384 LOC101355384 LOC101349117 LOC101349117 LOC101349766 LOC101349766 LOC101346782 LOC101346782 LOC101340589 LOC101340589 LOC101351271 LOC101351271 LOC101346170 LOC101346170
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101349393Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa)
LOC101356250Diablo homolog, mitochondrial isoform X1. (237 aa)
LOC101356564Apoptosis regulator BAX. (173 aa)
LOC101347007Apoptosis regulator Bcl-2 isoform X1. (229 aa)
LOC101345213Phorbol-12-myristate-13-acetate-induced protein 1. (54 aa)
LOC101357722Dynein light chain. (89 aa)
LOC10134920414-3-3 protein eta; Belongs to the 14-3-3 family. (246 aa)
LOC101341837LOW QUALITY PROTEIN: caspase-10; Belongs to the peptidase C14A family. (536 aa)
LOC101344302Caspase-8 isoform X1; Belongs to the peptidase C14A family. (477 aa)
LOC101359891Septin-4; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (477 aa)
LOC101340903pro-FMRFamide-related neuropeptide VF. (197 aa)
LOC101360930gasdermin-E. (497 aa)
LOC10134377614-3-3 protein sigma; Belongs to the 14-3-3 family. (248 aa)
LOC101354173Transmembrane protein 198. (360 aa)
LOC10134317514-3-3 protein epsilon; Belongs to the 14-3-3 family. (255 aa)
LOC101352493Bcl-2-like protein 11 isoform X1. (201 aa)
LOC101344706Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (496 aa)
LOC101346361Bcl-2-like protein 1 isoform X1. (233 aa)
LOC10135191414-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (245 aa)
LOC10135249914-3-3 protein beta/alpha isoform X1; Belongs to the 14-3-3 family. (248 aa)
LOC101354307Caspase-3 isoform X1; Belongs to the peptidase C14A family. (277 aa)
LOC101340375Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LOC101341834Dynein light chain. (103 aa)
LOC101346298Caspase-7 isoform X1; Belongs to the peptidase C14A family. (332 aa)
LOC101347432Cell death regulator Aven. (270 aa)
LOC101355103Caspase-9; Belongs to the peptidase C14A family. (448 aa)
LOC101346318E3 ubiquitin-protein ligase XIAP isoform X1. (497 aa)
LOC101350319Caspase recruitment domain-containing protein 8-like. (409 aa)
LOC101343394Calcineurin subunit B type 1 isoform X1. (170 aa)
LOC101351864Uncharacterized protein C6orf222 homolog. (681 aa)
LOC101358526Mitogen-activated protein kinase 1. (263 aa)
LOC101352047Bcl2-associated agonist of cell death. (167 aa)
LOC111822341Dynein light chain. (130 aa)
LOC101342121Bcl-2-related ovarian killer protein. (212 aa)
LOC101356396BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (200 aa)
LOC101345470Bcl-2-modifying factor isoform X1. (267 aa)
LOC101359074Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. (280 aa)
LOC101341801Bcl-2-like protein 2. (193 aa)
LOC101341201Bcl-2 homologous antagonist/killer. (212 aa)
LOC101355182LOW QUALITY PROTEIN: cytochrome c, testis-specific-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
LOC101357052LOW QUALITY PROTEIN: gasdermin-B. (355 aa)
LOC101358941LOW QUALITY PROTEIN: transmembrane protein 198-like. (403 aa)
LOC101354940LOW QUALITY PROTEIN: cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LOC105756562LOW QUALITY PROTEIN: caspase recruitment domain-containing protein 8-like. (364 aa)
LOC10135028614-3-3 protein theta; Belongs to the 14-3-3 family. (245 aa)
LOC101355384Septin-1 isoform X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (365 aa)
LOC101349117LOW QUALITY PROTEIN: uncharacterized protein C17orf47 homolog. (718 aa)
LOC101349766Septin-5; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (378 aa)
LOC101346782gasdermin-D. (489 aa)
LOC101340589Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (377 aa)
LOC101351271Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LOC10134617014-3-3 protein gamma; Belongs to the 14-3-3 family. (247 aa)
Your Current Organism:
Trichechus manatus
NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris
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