46 items (Trichechus manatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101346092	Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
	LOC101349243	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
	LOC101344416	cAMP-dependent protein kinase type I-beta regulatory subunit. (382 aa)
	LOC101354710	THAP domain-containing protein 7. (313 aa)
	LOC101355990	cAMP-dependent protein kinase catalytic subunit PRKX isoform X1; Belongs to the protein kinase superfamily. (353 aa)
	LOC101354868	Adenylate cyclase type 1. (903 aa)
	LOC101352296	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
	LOC101347445	Guanine nucleotide-binding protein subunit alpha-14. (355 aa)
	LOC101355886	THAP domain-containing protein 6. (222 aa)
	LOC101354282	cAMP-dependent protein kinase type II-beta regulatory subunit. (416 aa)
	LOC101351254	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
	LOC101343271	Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
	LOC101360334	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (977 aa)
	LOC101345890	Guanine nucleotide-binding protein subunit alpha-11. (354 aa)
	LOC101349028	Putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
	LOC101349290	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1144 aa)
	LOC101343253	Calcium/calmodulin-dependent protein kinase type IV isoform X3; Belongs to the protein kinase superfamily. (472 aa)
	LOC101354334	Calcium/calmodulin-dependent protein kinase kinase 1. (505 aa)
	LOC101349364	Phosphodiesterase. (549 aa)
	LOC101344705	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
	LOC101350704	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
	LOC101342638	cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (398 aa)
	LOC101341952	Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform X1. (355 aa)
	LOC101351637	cAMP-dependent protein kinase type II-alpha regulatory subunit. (400 aa)
	LOC101353945	Serine/threonine-protein kinase DCLK1; Belongs to the protein kinase superfamily. (433 aa)
	LOC111822155	Uncharacterized protein LOC111822155. (366 aa)
	LOC111822149	Putative serine/threonine-protein kinase PRKY. (77 aa)
	LOC101349835	Neurobeachin. (2955 aa)
	LOC101347192	Guanine nucleotide-binding protein G(Q) subunit alpha isoform X3. (381 aa)
	LOC101361375	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1166 aa)
	LOC101346598	Phosphodiesterase. (841 aa)
	LOC101344242	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1226 aa)
	LOC101349967	Phosphoinositide phospholipase C. (909 aa)
	LOC101343527	Guanine nucleotide-binding protein G(T) subunit alpha-3 isoform X1. (339 aa)
	LOC101347599	Lipopolysaccharide-responsive and beige-like anchor protein isoform X1. (2870 aa)
	LOC111820966	Guanine nucleotide-binding protein subunit alpha-15. (181 aa)
	LOC101347848	LOW QUALITY PROTEIN: calcium/calmodulin-dependent protein kinase kinase 2. (548 aa)
	LOC101346041	Adenylate cyclase type 5. (1265 aa)
	LOC101361935	Phosphodiesterase. (573 aa)
	LOC101341715	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1079 aa)
	LOC101345274	cAMP-dependent protein kinase type I-alpha regulatory subunit isoform X1. (411 aa)
	LOC101345270	Phospholipase A2. (757 aa)
	LOC101355651	Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa)
	LOC101348144	Cyclic nucleotide-binding domain-containing protein 2. (566 aa)
	LOC101348995	cAMP-dependent protein kinase catalytic subunit alpha. (293 aa)
	LOC101350438	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1076 aa)

Your Current Organism:

Trichechus manatus

NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101341715	LOC101341952	A0A2Y9QTT9	A0A2Y9D6E4	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform X1.	0.790
LOC101341715	LOC101342638	A0A2Y9QTT9	A0A2Y9D7C8	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily.	0.921
LOC101341715	LOC101343253	A0A2Y9QTT9	A0A2Y9DM22	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin-dependent protein kinase type IV isoform X3; Belongs to the protein kinase superfamily.	0.666
LOC101341715	LOC101343271	A0A2Y9QTT9	A0A2Y9DVT4	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(I) subunit alpha-1.	0.790
LOC101341715	LOC101343527	A0A2Y9QTT9	A0A2Y9R8U0	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(T) subunit alpha-3 isoform X1.	0.498
LOC101341715	LOC101344705	A0A2Y9QTT9	A0A2Y9DET0	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.619
LOC101341715	LOC101346041	A0A2Y9QTT9	A0A2Y9QYH5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 5.	0.625
LOC101341715	LOC101346092	A0A2Y9QTT9	A0A2Y9E7T2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(K) subunit alpha.	0.790
LOC101341715	LOC101346598	A0A2Y9QTT9	A0A2Y9RNY1	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.711
LOC101341715	LOC101348995	A0A2Y9QTT9	A0A2Y9QFS5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	cAMP-dependent protein kinase catalytic subunit alpha.	0.921
LOC101341715	LOC101349243	A0A2Y9QTT9	A0A2Y9E704	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.631
LOC101341715	LOC101349364	A0A2Y9QTT9	A0A2Y9DJ06	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.680
LOC101341715	LOC101350438	A0A2Y9QTT9	A0A2Y9EB92	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.597
LOC101341715	LOC101350704	A0A2Y9QTT9	A0A2Y9DED6	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.427
LOC101341715	LOC101351254	A0A2Y9QTT9	A0A2Y9DWD1	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.687
LOC101341715	LOC101354868	A0A2Y9QTT9	A0A2Y9E2X0	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 1.	0.488
LOC101341715	LOC101355651	A0A2Y9QTT9	A0A2Y9QNQ7	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.908
LOC101341715	LOC101360334	A0A2Y9QTT9	A0A2Y9DTY2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.411
LOC101341715	LOC101361935	A0A2Y9QTT9	A0A2Y9QTY9	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.680
LOC101341952	LOC101341715	A0A2Y9D6E4	A0A2Y9QTT9	Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform X1.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.790