STRINGSTRING
LOC101355101 LOC101355101 LOC101358103 LOC101358103 LOC101343228 LOC101343228 LOC101359597 LOC101359597 LOC101359592 LOC101359592 LOC101344924 LOC101344924 LOC101359012 LOC101359012 LOC101344115 LOC101344115 LOC101347746 LOC101347746 LOC101352874 LOC101352874 LOC101342748 LOC101342748 LOC101344230 LOC101344230 LOC101348884 LOC101348884 LOC101350991 LOC101350991 LOC101349043 LOC101349043 LOC101358075 LOC101358075 LOC101355115 LOC101355115 LOC101346141 LOC101346141 LOC101356218 LOC101356218 LOC101343014 LOC101343014 LOC101344090 LOC101344090 LOC101359491 LOC101359491 LOC101343281 LOC101343281 LOC101344163 LOC101344163 LOC101357916 LOC101357916 LOC101343102 LOC101343102 LOC101358608 LOC101358608 LOC101358678 LOC101358678 LOC101356005 LOC101356005 LOC101347672 LOC101347672 LOC101348102 LOC101348102 LOC101347748 LOC101347748 LOC101344782 LOC101344782 LOC101342804 LOC101342804 LOC101352934 LOC101352934 LOC101346861 LOC101346861 LOC101355809 LOC101355809 LOC101342891 LOC101342891 LOC101356016 LOC101356016 LOC101354148 LOC101354148 LOC101342651 LOC101342651 LOC101344047 LOC101344047 LOC101340945 LOC101340945 LOC101354865 LOC101354865 LOC101344666 LOC101344666 LOC101360003 LOC101360003 LOC101360702 LOC101360702 LOC101343804 LOC101343804 LOC101346849 LOC101346849 LOC101347197 LOC101347197 LOC101347525 LOC101347525 LOC101343407 LOC101343407 LOC101359278 LOC101359278
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101355101Fibronectin type-III domain-containing protein 3A isoform X1. (1199 aa)
LOC101358103Thrombospondin-2. (1334 aa)
LOC101343228Osteopontin. (304 aa)
LOC1013595971-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
LOC101359592Son of sevenless homolog 1 isoform X1. (1333 aa)
LOC101344924Collagen alpha-3(IX) chain. (680 aa)
LOC101359012Growth factor receptor-bound protein 2. (176 aa)
LOC101344115Platelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
LOC101347746Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
LOC101352874Thrombospondin-4. (964 aa)
LOC101342748Adapter molecule crk isoform X1. (304 aa)
LOC101344230GTPase NRas isoform X1. (189 aa)
LOC101348884Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
LOC101350991Plasminogen activator; Belongs to the peptidase S1 family. (563 aa)
LOC101349043Enhancer of filamentation 1 isoform X2. (825 aa)
LOC101358075Platelet-derived growth factor C isoform X1; Belongs to the PDGF/VEGF growth factor family. (345 aa)
LOC101355115Cytoplasmic protein. (377 aa)
LOC101346141LOW QUALITY PROTEIN: proprotein convertase subtilisin/kexin type 4. (850 aa)
LOC101356218Growth factor receptor-bound protein 7 isoform X1. (531 aa)
LOC101343014Signal transducer and activator of transcription. (847 aa)
LOC101344090Cas scaffolding protein family member 4. (662 aa)
LOC101359491Collagen alpha-1(III) chain. (1160 aa)
LOC101343281Collagen alpha-1(II) chain. (1418 aa)
LOC101344163Collagen alpha-3(VI) chain. (3183 aa)
LOC101357916Signal transducer and activator of transcription. (752 aa)
LOC101343102Cold shock domain-containing protein E1 isoform X5. (844 aa)
LOC101358608Fibronectin type III domain-containing protein 3B isoform X1. (1238 aa)
LOC101358678Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1082 aa)
LOC101356005Cytoplasmic protein. (380 aa)
LOC101347672LOW QUALITY PROTEIN: GTPase ERas. (276 aa)
LOC101348102Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
LOC101347748Von Willebrand factor A domain-containing protein 2. (732 aa)
LOC101344782Rap guanine nucleotide exchange factor 1 isoform X1. (1145 aa)
LOC101342804GTPase HRas isoform X1. (189 aa)
LOC101352934Thrombospondin-3 isoform X1. (956 aa)
LOC101346861Breast cancer anti-estrogen resistance protein 1. (840 aa)
LOC101355809Crk-like protein. (303 aa)
LOC101342891Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (810 aa)
LOC101356016Furin; Belongs to the peptidase S8 family. (796 aa)
LOC101354148Signal transducer and activator of transcription 5B. (581 aa)
LOC101342651Signal transducer and activator of transcription. (783 aa)
LOC101344047Thrombospondin-1. (1170 aa)
LOC101340945Embryonal Fyn-associated substrate isoform X1. (551 aa)
LOC101354865Collagen alpha-2(V) chain. (1499 aa)
LOC101344666Platelet-derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa)
LOC101360003Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1110 aa)
LOC101360702Platelet-derived growth factor D; Belongs to the PDGF/VEGF growth factor family. (370 aa)
LOC101343804Phosphatidylinositol 3-kinase regulatory subunit beta. (729 aa)
LOC101346849Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC101347197Collagen alpha-1(VI) chain. (1027 aa)
LOC101347525GTPase KRas isoform X3. (227 aa)
LOC101343407Signal transducer and activator of transcription. (799 aa)
LOC101359278Ras GTPase-activating protein 1. (1016 aa)
Your Current Organism:
Trichechus manatus
NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris
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