40 items (Trichechus manatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101342804	GTPase HRas isoform X1. (189 aa)
	LOC101346344	MAP kinase-activated protein kinase 3 isoform X1; Belongs to the protein kinase superfamily. (384 aa)
	LOC101359592	Son of sevenless homolog 1 isoform X1. (1333 aa)
	LOC101359012	Growth factor receptor-bound protein 2. (176 aa)
	LOC101343332	Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
	LOC101342996	MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (400 aa)
	LOC101342748	Adapter molecule crk isoform X1. (304 aa)
	LOC101359726	SHC-transforming protein 2. (428 aa)
	LOC101341078	Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
	LOC101361614	Mitogen-activated protein kinase. (283 aa)
	LOC101341922	Beta-nerve growth factor; Belongs to the NGF-beta family. (242 aa)
	LOC101344230	GTPase NRas isoform X1. (189 aa)
	LOC101360159	GTP-binding protein Rit2. (218 aa)
	LOC101354107	Ras-related protein Ral-A. (206 aa)
	LOC101360084	SHC-transforming protein 3. (616 aa)
	LOC101347525	GTPase KRas isoform X3. (227 aa)
	LOC101355900	SHC-transforming protein 4. (629 aa)
	LOC101340589	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (377 aa)
	LOC101355809	Crk-like protein. (303 aa)
	LOC101347379	GTP-binding protein Rit1 isoform X1. (219 aa)
	LOC101358105	SHC-transforming protein 1 isoform X1. (584 aa)
	LOC101353421	Serine/threonine-protein kinase B-raf. (743 aa)
	LOC101353366	LOW QUALITY PROTEIN: ral guanine nucleotide dissociation stimulator-like. (349 aa)
	LOC101351825	Ral guanine nucleotide dissociation stimulator-like. (613 aa)
	LOC101348205	LOW QUALITY PROTEIN: ral guanine nucleotide dissociation stimulator-like. (579 aa)
	LOC101350670	Fibroblast growth factor receptor substrate 2 isoform X1. (537 aa)
	LOC101342129	Ras-related protein Ral-B. (206 aa)
	LOC101350678	NTPase KAP family P-loop domain-containing protein 1. (459 aa)
	LOC101352499	14-3-3 protein beta/alpha isoform X1; Belongs to the 14-3-3 family. (248 aa)
	LOC101344782	Rap guanine nucleotide exchange factor 1 isoform X1. (1145 aa)
	LOC101352699	Kinase D-interacting substrate of 220 kDa isoform X1. (1753 aa)
	LOC101348938	Ral guanine nucleotide dissociation stimulator isoform X1. (941 aa)
	LOC101347350	Mitogen-activated protein kinase. (321 aa)
	LOC101347672	LOW QUALITY PROTEIN: GTPase ERas. (276 aa)
	LOC101343102	Cold shock domain-containing protein E1 isoform X5. (844 aa)
	LOC101344395	Iron-sulfur cluster assembly 1 homolog, mitochondrial isoform X1. (208 aa)
	LOC101348972	LOW QUALITY PROTEIN: ral guanine nucleotide dissociation stimulator-like. (364 aa)
	LOC101358526	Mitogen-activated protein kinase 1. (263 aa)
	LOC101349734	LOW QUALITY PROTEIN: ral guanine nucleotide dissociation stimulator-like. (585 aa)
	LOC101351378	Tyrosine-protein kinase receptor. (770 aa)

Your Current Organism:

Trichechus manatus

NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101340589	LOC101341078	A0A2Y9E433	A0A2Y9DQ05	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily.	0.972
LOC101340589	LOC101342804	A0A2Y9E433	A0A2Y9QL66	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	GTPase HRas isoform X1.	0.937
LOC101340589	LOC101342996	A0A2Y9E433	A0A2Y9DII9	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily.	0.695
LOC101340589	LOC101343332	A0A2Y9E433	A0A2Y9DHL4	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.	0.972
LOC101340589	LOC101344230	A0A2Y9E433	A0A2Y9DST5	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	GTPase NRas isoform X1.	0.937
LOC101340589	LOC101346344	A0A2Y9E433	A0A2Y9D6E8	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	MAP kinase-activated protein kinase 3 isoform X1; Belongs to the protein kinase superfamily.	0.693
LOC101340589	LOC101347350	A0A2Y9E433	A0A2Y9R6Y7	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase.	0.948
LOC101340589	LOC101347525	A0A2Y9E433	A0A2Y9DZS8	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	GTPase KRas isoform X3.	0.937
LOC101340589	LOC101350670	A0A2Y9E433	A0A2Y9G3T7	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Fibroblast growth factor receptor substrate 2 isoform X1.	0.466
LOC101340589	LOC101352499	A0A2Y9E433	A0A2Y9QLK9	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	14-3-3 protein beta/alpha isoform X1; Belongs to the 14-3-3 family.	0.477
LOC101340589	LOC101353421	A0A2Y9E433	A0A2Y9FYY4	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Serine/threonine-protein kinase B-raf.	0.600
LOC101340589	LOC101358526	A0A2Y9E433	A0A2Y9RRM5	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase 1.	0.900
LOC101340589	LOC101359012	A0A2Y9E433	A0A2Y9DGF8	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Growth factor receptor-bound protein 2.	0.450
LOC101340589	LOC101361614	A0A2Y9E433	A0A2Y9DQX7	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase.	0.948
LOC101341078	LOC101340589	A0A2Y9DQ05	A0A2Y9E433	Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.972
LOC101341078	LOC101342129	A0A2Y9DQ05	A0A2Y9G4I6	Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily.	Ras-related protein Ral-B.	0.518
LOC101341078	LOC101342804	A0A2Y9DQ05	A0A2Y9QL66	Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily.	GTPase HRas isoform X1.	0.949
LOC101341078	LOC101343102	A0A2Y9DQ05	A0A2Y9RFC2	Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily.	Cold shock domain-containing protein E1 isoform X5.	0.518
LOC101341078	LOC101343332	A0A2Y9DQ05	A0A2Y9DHL4	Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily.	Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.	0.901
LOC101341078	LOC101344230	A0A2Y9DQ05	A0A2Y9DST5	Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily.	GTPase NRas isoform X1.	0.949