57 items (Trichechus manatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101342107	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	LOC101347445	Guanine nucleotide-binding protein subunit alpha-14. (355 aa)
	LOC101348280	Guanine nucleotide-binding protein subunit beta-4. (340 aa)
	LOC101350581	AP-3 complex subunit mu-2; Belongs to the adaptor complexes medium subunit family. (418 aa)
	LOC101344313	Prefoldin subunit 1. (122 aa)
	LOC101347765	T-complex protein 1 subunit zeta. (531 aa)
	LOC111821467	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
	LOC101345890	Guanine nucleotide-binding protein subunit alpha-11. (354 aa)
	LOC101347192	Guanine nucleotide-binding protein G(Q) subunit alpha isoform X3. (381 aa)
	LOC101351139	Prefoldin subunit 5. (154 aa)
	LOC101349439	Sphingosine kinase 1. (471 aa)
	LOC101347241	Regulator of G-protein signaling 9. (683 aa)
	LOC101349445	Regulator of G-protein signaling 7. (470 aa)
	LOC101341327	Guanine nucleotide-binding protein subunit beta-5. (353 aa)
	LOC111819060	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
	LOC101351554	Prefoldin subunit 6. (129 aa)
	LOC101352593	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (119 aa)
	LOC101350263	Casein kinase II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (391 aa)
	LOC101353114	Regulator of G-protein signaling 6 isoform X1. (432 aa)
	LOC111819711	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	LOC101344505	T-complex protein 1 subunit alpha isoform X1. (556 aa)
	LOC101360567	Regulator of G-protein signaling 11. (472 aa)
	LOC101351136	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
	LOC101357541	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	LOC101344773	Phosducin. (246 aa)
	LOC101350187	T-complex protein 1 subunit theta-like 2. (554 aa)
	LOC101342229	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 isoform X1. (1850 aa)
	LOC101349005	Casein kinase II subunit alpha' isoform X1; Belongs to the protein kinase superfamily. (350 aa)
	LOC101361581	T-complex protein 1 subunit theta. (548 aa)
	LOC101353211	Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family. (134 aa)
	LOC101341130	Brefeldin A-inhibited guanine nucleotide-exchange protein 2. (1789 aa)
	LOC101355920	Protein FAM161A. (712 aa)
	LOC101355492	T-complex protein 1 subunit delta. (539 aa)
	LOC101352325	T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (543 aa)
	LOC101345326	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	LOC101356302	Phosducin-like protein. (300 aa)
	LOC101351188	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
	LOC111820966	Guanine nucleotide-binding protein subunit alpha-15. (181 aa)
	LOC101360148	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
	LOC101347845	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 isoform X1. (112 aa)
	LOC101357336	Endoplasmic reticulum membrane-associated RNA degradation protein isoform X1. (679 aa)
	LOC101357692	Lymphocyte antigen 6 complex locus protein G5b. (197 aa)
	LOC101345345	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
	LOC101347979	Peptidylprolyl isomerase. (582 aa)
	LOC101360822	Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family. (197 aa)
	LOC101351129	Prefoldin subunit 2. (154 aa)
	LOC101342893	T-complex protein 1 subunit gamma. (545 aa)
	LOC101345319	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
	LOC101355136	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
	LOC101341777	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
	LOC101350917	T-complex protein 1 subunit beta. (535 aa)
	LOC101342034	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
	LOC101345316	Peptidylprolyl isomerase. (574 aa)
	LOC101348037	T-complex protein 1 subunit zeta-2. (577 aa)
	LOC101345721	T-complex protein 1 subunit epsilon; Belongs to the TCP-1 chaperonin family. (152 aa)
	LOC101350742	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
	LOC101349721	AP-3 complex subunit mu-1 isoform X1; Belongs to the adaptor complexes medium subunit family. (447 aa)

Your Current Organism:

Trichechus manatus

NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101341130	LOC101342229	A0A2Y9D9T6	A0A2Y9DDH3	Brefeldin A-inhibited guanine nucleotide-exchange protein 2.	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 isoform X1.	0.557
LOC101341130	LOC101357336	A0A2Y9D9T6	A0A2Y9FVI2	Brefeldin A-inhibited guanine nucleotide-exchange protein 2.	Endoplasmic reticulum membrane-associated RNA degradation protein isoform X1.	0.512
LOC101341327	LOC101341777	A0A2Y9FX69	A0A2Y9E4T8	Guanine nucleotide-binding protein subunit beta-5.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.721
LOC101341327	LOC101342034	A0A2Y9FX69	A0A2Y9E370	Guanine nucleotide-binding protein subunit beta-5.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.721
LOC101341327	LOC101342107	A0A2Y9FX69	A0A2Y9DYR5	Guanine nucleotide-binding protein subunit beta-5.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.958
LOC101341327	LOC101342893	A0A2Y9FX69	A0A2Y9E8K7	Guanine nucleotide-binding protein subunit beta-5.	T-complex protein 1 subunit gamma.	0.552
LOC101341327	LOC101344505	A0A2Y9FX69	A0A2Y9D6S2	Guanine nucleotide-binding protein subunit beta-5.	T-complex protein 1 subunit alpha isoform X1.	0.562
LOC101341327	LOC101344773	A0A2Y9FX69	A0A2Y9DE50	Guanine nucleotide-binding protein subunit beta-5.	Phosducin.	0.822
LOC101341327	LOC101345319	A0A2Y9FX69	A0A2Y9E5X9	Guanine nucleotide-binding protein subunit beta-5.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2.	0.402
LOC101341327	LOC101345326	A0A2Y9FX69	A0A2Y9D772	Guanine nucleotide-binding protein subunit beta-5.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.957
LOC101341327	LOC101345721	A0A2Y9FX69	A0A2Y9RG78	Guanine nucleotide-binding protein subunit beta-5.	T-complex protein 1 subunit epsilon; Belongs to the TCP-1 chaperonin family.	0.950
LOC101341327	LOC101345890	A0A2Y9FX69	A0A2Y9DQ23	Guanine nucleotide-binding protein subunit beta-5.	Guanine nucleotide-binding protein subunit alpha-11.	0.730
LOC101341327	LOC101347192	A0A2Y9FX69	A0A2Y9RPL6	Guanine nucleotide-binding protein subunit beta-5.	Guanine nucleotide-binding protein G(Q) subunit alpha isoform X3.	0.730
LOC101341327	LOC101347241	A0A2Y9FX69	A0A2Y9DHI8	Guanine nucleotide-binding protein subunit beta-5.	Regulator of G-protein signaling 9.	0.886
LOC101341327	LOC101347445	A0A2Y9FX69	A0A2Y9DXP6	Guanine nucleotide-binding protein subunit beta-5.	Guanine nucleotide-binding protein subunit alpha-14.	0.730
LOC101341327	LOC101347765	A0A2Y9FX69	A0A2Y9DUW8	Guanine nucleotide-binding protein subunit beta-5.	T-complex protein 1 subunit zeta.	0.481
LOC101341327	LOC101347845	A0A2Y9FX69	A0A2Y9R6L6	Guanine nucleotide-binding protein subunit beta-5.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 isoform X1.	0.954
LOC101341327	LOC101348037	A0A2Y9FX69	A0A2Y9E1N3	Guanine nucleotide-binding protein subunit beta-5.	T-complex protein 1 subunit zeta-2.	0.481
LOC101341327	LOC101348280	A0A2Y9FX69	A0A2Y9DWK4	Guanine nucleotide-binding protein subunit beta-5.	Guanine nucleotide-binding protein subunit beta-4.	0.402
LOC101341327	LOC101349445	A0A2Y9FX69	A0A2Y9DK58	Guanine nucleotide-binding protein subunit beta-5.	Regulator of G-protein signaling 7.	0.887