STRINGSTRING
LOC101345005 LOC101345005 LOC101348994 LOC101348994 LOC101345183 LOC101345183 LOC101341554 LOC101341554 LOC101359250 LOC101359250 LOC101360911 LOC101360911 LOC101356704 LOC101356704 LOC101348827 LOC101348827 LOC101342060 LOC101342060 LOC101355826 LOC101355826 LOC101346187 LOC101346187 LOC101352082 LOC101352082 LOC101358885 LOC101358885 LOC101344747 LOC101344747 LOC101344933 LOC101344933 LOC101346477 LOC101346477 LOC101361433 LOC101361433 LOC101356054 LOC101356054 LOC101341654 LOC101341654 LOC101341621 LOC101341621 LOC101361627 LOC101361627 LOC101351693 LOC101351693 LOC101340472 LOC101340472 LOC101353682 LOC101353682 LOC101349983 LOC101349983 LOC101352422 LOC101352422 LOC101351101 LOC101351101 LOC101356505 LOC101356505 LOC101344992 LOC101344992 LOC101359762 LOC101359762 LOC101345414 LOC101345414 LOC101361983 LOC101361983 LOC101347133 LOC101347133 LOC101342810 LOC101342810 LOC101340422 LOC101340422 LOC101348322 LOC101348322 LOC101351200 LOC101351200 LOC101346883 LOC101346883 LOC101357690 LOC101357690 LOC101354396 LOC101354396 LOC101354564 LOC101354564 LOC101351312 LOC101351312 LOC101346461 LOC101346461 LOC101347740 LOC101347740 LOC101356454 LOC101356454 LOC101355428 LOC101355428 LOC101348250 LOC101348250 LOC101349534 LOC101349534 LOC101351406 LOC101351406 LOC101353736 LOC101353736 LOC101360313 LOC101360313 LOC101347661 LOC101347661 LOC101359620 LOC101359620 LOC101343598 LOC101343598 LOC101360142 LOC101360142 LOC101342083 LOC101342083 LOC101355611 LOC101355611 LOC101356386 LOC101356386 LOC101359024 LOC101359024 LOC101358150 LOC101358150 LOC101347003 LOC101347003 LOC101348858 LOC101348858 LOC101357721 LOC101357721 LOC101350207 LOC101350207 LOC101348872 LOC101348872 LOC101346061 LOC101346061 LOC101359902 LOC101359902 LOC101346758 LOC101346758 LOC101358856 LOC101358856 LOC101362049 LOC101362049 LOC101351254 LOC101351254 LOC101340313 LOC101340313 LOC101357820 LOC101357820 LOC101355548 LOC101355548 LOC101351436 LOC101351436 LOC101359840 LOC101359840 LOC101355804 LOC101355804 LOC101345656 LOC101345656 LOC101353268 LOC101353268 LOC101354620 LOC101354620 LOC101361647 LOC101361647 LOC101355652 LOC101355652 LOC101349745 LOC101349745 LOC101352160 LOC101352160 LOC101347799 LOC101347799 LOC101343402 LOC101343402 LOC101343830 LOC101343830 LOC101340678 LOC101340678
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC10134500526S proteasome non-ATPase regulatory subunit 4. (379 aa)
LOC101348994Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (650 aa)
LOC101345183Proteasome activator complex subunit 2. (239 aa)
LOC101341554Proteasome subunit beta. (219 aa)
LOC101359250Proteasome activator complex subunit 3 isoform X1. (254 aa)
LOC10136091126S proteasome regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
LOC10135670426S proteasome regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
LOC101348827Proteasome subunit beta. (263 aa)
LOC101342060Proteasome subunit beta. (276 aa)
LOC10135582626S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
LOC101346187AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (940 aa)
LOC101352082Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1851 aa)
LOC101358885Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
LOC10134474726S proteasome non-ATPase regulatory subunit 6. (340 aa)
LOC101344933Proteasome activator complex subunit 1 isoform X1. (282 aa)
LOC10134647726S proteasome non-ATPase regulatory subunit 14. (310 aa)
LOC101361433Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (470 aa)
LOC101356054Ras-related C3 botulinum toxin substrate 1. (148 aa)
LOC10134165426S proteasome regulatory subunit 4. (329 aa)
LOC101341621Proteasome activator complex subunit 4 isoform X1. (1865 aa)
LOC101361627AP-2 complex subunit mu isoform X1; Belongs to the adaptor complexes medium subunit family. (435 aa)
LOC101351693E3 ubiquitin-protein ligase. (756 aa)
LOC101340472AP-2 complex subunit sigma isoform X1. (172 aa)
LOC101353682Segment polarity protein dishevelled homolog DVL-1 isoform X1. (700 aa)
LOC101349983Prickle-like protein 1. (832 aa)
LOC101352422Proteasome subunit alpha type. (263 aa)
LOC101351101AP complex subunit beta. (951 aa)
LOC101356505Proteasome subunit alpha type. (261 aa)
LOC101344992Prickle-like protein 2. (842 aa)
LOC101359762Proteasome subunit beta. (241 aa)
LOC101345414Inactive tyrosine-protein kinase transmembrane receptor ROR1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (936 aa)
LOC101361983ubiquitin-40S ribosomal protein S27a. (156 aa)
LOC101347133Proteasome subunit alpha type. (248 aa)
LOC101342810Disheveled-associated activator of morphogenesis 1. (1069 aa)
LOC101340422Proteasome subunit alpha type. (255 aa)
LOC101348322Frizzled-6; Belongs to the G-protein coupled receptor Fz/Smo family. (719 aa)
LOC101351200Proteasome inhibitor PI31 subunit isoform X1. (271 aa)
LOC101346883Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (211 aa)
LOC101357690Partitioning defective 6 homolog alpha isoform X2. (344 aa)
LOC10135439626S proteasome regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa)
LOC101354564Proteasome subunit beta. (273 aa)
LOC10135131226S proteasome non-ATPase regulatory subunit 5 isoform X1. (504 aa)
LOC101346461Proteasome subunit beta. (201 aa)
LOC101347740Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (218 aa)
LOC101356454Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
LOC101355428Ras-related C3 botulinum toxin substrate 2 isoform X1. (192 aa)
LOC101348250Protein kinase C alpha type isoform X2. (549 aa)
LOC10134953426S proteasome non-ATPase regulatory subunit 12. (456 aa)
LOC101351406E3 ubiquitin-protein ligase. (748 aa)
LOC10135373626S proteasome regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
LOC101360313Ras-related C3 botulinum toxin substrate 3. (188 aa)
LOC101347661Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (566 aa)
LOC101359620Proteasome subunit beta. (277 aa)
LOC101343598Proteasome subunit beta. (239 aa)
LOC101360142Segment polarity protein dishevelled homolog DVL-2. (736 aa)
LOC101342083Prickle planar cell polarity protein 3 isoform X1. (606 aa)
LOC101355611Proteasome subunit alpha type. (246 aa)
LOC101356386Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa)
LOC10135902426S proteasome non-ATPase regulatory subunit 3. (531 aa)
LOC101358150Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
LOC101347003Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
LOC101348858Proteasome subunit beta. (205 aa)
LOC101357721FH2 domain-containing protein 1. (1144 aa)
LOC101350207Prickle-like protein 4. (421 aa)
LOC10134887226S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
LOC101346061Disheveled-associated activator of morphogenesis 2 isoform X1. (1067 aa)
LOC101359902Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
LOC101346758AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (956 aa)
LOC10135885626S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (907 aa)
LOC101362049Segment polarity protein dishevelled homolog DVL-3. (716 aa)
LOC101351254Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
LOC101340313Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
LOC101357820Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
LOC101355548Proteasome subunit alpha type. (234 aa)
LOC10135143626S proteasome non-ATPase regulatory subunit 7. (324 aa)
LOC101359840Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
LOC10135580426S proteasome non-ATPase regulatory subunit 9. (225 aa)
LOC10134565626S proteasome non-ATPase regulatory subunit 11. (422 aa)
LOC10135326826S proteasome regulatory subunit 6A; Belongs to the AAA ATPase family. (436 aa)
LOC101354620Proteasome subunit alpha type. (256 aa)
LOC101361647Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (472 aa)
LOC10135565226S proteasome non-ATPase regulatory subunit 8. (348 aa)
LOC101349745Tyrosine-protein kinase transmembrane receptor ROR2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (909 aa)
LOC101352160Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
LOC101347799Proteasome subunit alpha type. (241 aa)
LOC101343402Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
LOC101343830Proteasome subunit beta. (263 aa)
LOC10134067826S proteasome non-ATPase regulatory subunit 13. (376 aa)
Your Current Organism:
Trichechus manatus
NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.