STRINGSTRING
LOC101358856 LOC101358856 LOC101360163 LOC101360163 LOC101355548 LOC101355548 LOC101351436 LOC101351436 LOC101348454 LOC101348454 LOC101340393 LOC101340393 LOC101350591 LOC101350591 LOC101355804 LOC101355804 LOC101350329 LOC101350329 LOC101345331 LOC101345331 LOC101351256 LOC101351256 LOC101343394 LOC101343394 LOC101341621 LOC101341621 LOC101341654 LOC101341654 LOC101341153 LOC101341153 LOC101346477 LOC101346477 LOC101355146 LOC101355146 LOC101344933 LOC101344933 LOC101355651 LOC101355651 LOC101354147 LOC101354147 LOC111819543 LOC111819543 LOC101344747 LOC101344747 LOC101348995 LOC101348995 LOC111819196 LOC111819196 LOC101359059 LOC101359059 LOC101355826 LOC101355826 LOC101357919 LOC101357919 LOC105756391 LOC105756391 LOC101342060 LOC101342060 LOC101348827 LOC101348827 LOC101356704 LOC101356704 LOC101360911 LOC101360911 LOC101359250 LOC101359250 LOC101355476 LOC101355476 LOC101345656 LOC101345656 LOC101340854 LOC101340854 LOC101356505 LOC101356505 LOC101353268 LOC101353268 LOC101354620 LOC101354620 LOC101356158 LOC101356158 LOC101355652 LOC101355652 LOC101361050 LOC101361050 LOC101341554 LOC101341554 LOC101357860 LOC101357860 LOC101347574 LOC101347574 LOC101345183 LOC101345183 LOC101345005 LOC101345005 LOC101340678 LOC101340678 LOC101343830 LOC101343830 LOC101343402 LOC101343402 LOC101346094 LOC101346094 LOC101347799 LOC101347799 LOC101351200 LOC101351200 LOC101354396 LOC101354396 LOC101352434 LOC101352434 LOC101354564 LOC101354564 LOC101351312 LOC101351312 LOC101346461 LOC101346461 LOC101344618 LOC101344618 LOC101353473 LOC101353473 LOC101353037 LOC101353037 LOC101344282 LOC101344282 LOC101353040 LOC101353040 LOC101359762 LOC101359762 LOC101342638 LOC101342638 LOC101343916 LOC101343916 LOC101361983 LOC101361983 LOC101347552 LOC101347552 LOC101345935 LOC101345935 LOC101352683 LOC101352683 LOC101347133 LOC101347133 LOC101341290 LOC101341290 LOC101340422 LOC101340422 LOC101355751 LOC101355751 LOC111822611 LOC111822611 LOC101346175 LOC101346175 LOC101345156 LOC101345156 IL1B IL1B LOC101350094 LOC101350094 LOC101349922 LOC101349922 LOC105755977 LOC105755977 LOC101345921 LOC101345921 LOC101345665 LOC101345665 LOC101346433 LOC101346433 LOC111822114 LOC111822114 LOC101351806 LOC101351806 LOC101347466 LOC101347466 LOC101347711 LOC101347711 LOC101361963 LOC101361963 LOC101361706 LOC101361706 LOC101342036 LOC101342036 LOC101354775 LOC101354775 LOC101349534 LOC101349534 LOC101353736 LOC101353736 LOC101352703 LOC101352703 LOC101343418 LOC101343418 LOC101349614 LOC101349614 LOC101359620 LOC101359620 LOC101343598 LOC101343598 LOC101355353 LOC101355353 LOC101355611 LOC101355611 LOC101346393 LOC101346393 LOC101359024 LOC101359024 LOC101344302 LOC101344302 LOC101341837 LOC101341837 LOC101348858 LOC101348858 LOC101343517 LOC101343517 LOC101348872 LOC101348872 LOC101351866 LOC101351866 LOC101352422 LOC101352422
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC10135885626S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (907 aa)
LOC101360163Cullin-1; Belongs to the cullin family. (776 aa)
LOC101355548Proteasome subunit alpha type. (234 aa)
LOC10135143626S proteasome non-ATPase regulatory subunit 7. (324 aa)
LOC101348454Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
LOC101340393kxDL motif-containing protein 1. (177 aa)
LOC101350591S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
LOC10135580426S proteasome non-ATPase regulatory subunit 9. (225 aa)
LOC101350329Nuclear factor of activated T-cells 5 isoform X2. (1547 aa)
LOC101345331TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
LOC101351256Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (756 aa)
LOC101343394Calcineurin subunit B type 1 isoform X1. (170 aa)
LOC101341621Proteasome activator complex subunit 4 isoform X1. (1865 aa)
LOC10134165426S proteasome regulatory subunit 4. (329 aa)
LOC101341153Mitogen-activated protein kinase kinase kinase 20 isoform X1. (810 aa)
LOC10134647726S proteasome non-ATPase regulatory subunit 14. (310 aa)
LOC101355146TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (693 aa)
LOC101344933Proteasome activator complex subunit 1 isoform X1. (282 aa)
LOC101355651Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa)
LOC101354147F-box/WD repeat-containing protein 11 isoform X1. (563 aa)
LOC111819543Uncharacterized protein LOC111819543. (1058 aa)
LOC10134474726S proteasome non-ATPase regulatory subunit 6. (340 aa)
LOC101348995cAMP-dependent protein kinase catalytic subunit alpha. (293 aa)
LOC111819196Ubiquitin-conjugating enzyme E2 N-like. (267 aa)
LOC101359059Nuclear factor of activated T-cells, cytoplasmic 1 isoform X1. (933 aa)
LOC10135582626S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
LOC101357919Apoptosis-associated speck-like protein containing a CARD. (205 aa)
LOC105756391CD209 antigen-like protein 2. (208 aa)
LOC101342060Proteasome subunit beta. (276 aa)
LOC101348827Proteasome subunit beta. (263 aa)
LOC10135670426S proteasome regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
LOC10136091126S proteasome regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
LOC101359250Proteasome activator complex subunit 3 isoform X1. (254 aa)
LOC101355476TGF-beta-activated kinase 1 and MAP3K7-binding protein 3. (717 aa)
LOC10134565626S proteasome non-ATPase regulatory subunit 11. (422 aa)
LOC101340854Caspase recruitment domain-containing protein 11. (1155 aa)
LOC101356505Proteasome subunit alpha type. (261 aa)
LOC10135326826S proteasome regulatory subunit 6A; Belongs to the AAA ATPase family. (436 aa)
LOC101354620Proteasome subunit alpha type. (256 aa)
LOC101356158NEDD8-conjugating enzyme Ubc12; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
LOC10135565226S proteasome non-ATPase regulatory subunit 8. (348 aa)
LOC101361050Caspase recruitment domain-containing protein 9 isoform X1. (537 aa)
LOC101341554Proteasome subunit beta. (219 aa)
LOC101357860High affinity immunoglobulin epsilon receptor subunit gamma. (85 aa)
LOC101347574NF-kappa-B essential modulator isoform X1. (421 aa)
LOC101345183Proteasome activator complex subunit 2. (239 aa)
LOC10134500526S proteasome non-ATPase regulatory subunit 4. (379 aa)
LOC10134067826S proteasome non-ATPase regulatory subunit 13. (376 aa)
LOC101343830Proteasome subunit beta. (263 aa)
LOC101343402Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
LOC101346094Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
LOC101347799Proteasome subunit alpha type. (241 aa)
LOC101351200Proteasome inhibitor PI31 subunit isoform X1. (271 aa)
LOC10135439626S proteasome regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa)
LOC101352434Nuclear factor of activated T-cells, cytoplasmic 3 isoform X1. (1074 aa)
LOC101354564Proteasome subunit beta. (273 aa)
LOC10135131226S proteasome non-ATPase regulatory subunit 5 isoform X1. (504 aa)
LOC101346461Proteasome subunit beta. (201 aa)
LOC101344618TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (504 aa)
LOC101353473NEDD8-activating enzyme E1 catalytic subunit isoform X1. (462 aa)
LOC101353037Tyrosine-protein kinase. (512 aa)
LOC101344282CREB-binding protein. (2447 aa)
LOC1013530403-phosphoinositide-dependent protein kinase 1. (636 aa)
LOC101359762Proteasome subunit beta. (241 aa)
LOC101342638cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (398 aa)
LOC101343916WD repeat-containing protein 92 isoform X1. (357 aa)
LOC101361983ubiquitin-40S ribosomal protein S27a. (156 aa)
LOC101347552B-cell lymphoma/leukemia 10. (233 aa)
LOC101345935F-box/WD repeat-containing protein 1A isoform X1. (605 aa)
LOC101352683Nuclear factor NF-kappa-B p100 subunit isoform X1. (894 aa)
LOC101347133Proteasome subunit alpha type. (248 aa)
LOC101341290Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (745 aa)
LOC101340422Proteasome subunit alpha type. (255 aa)
LOC101355751Nuclear factor of activated T-cells, cytoplasmic 2 isoform X1. (930 aa)
LOC111822611C-type lectin domain family 4 member C-like. (154 aa)
LOC101346175C-type lectin domain family 4 member A-like isoform X1. (236 aa)
LOC101345156C-type lectin domain family 4 member E isoform X1. (223 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (262 aa)
LOC101350094C-type lectin domain family 7 member A isoform X1. (249 aa)
LOC101349922Transcription factor RelB. (424 aa)
LOC105755977Ubiquitin-conjugating enzyme E2 variant 1 isoform X1. (158 aa)
LOC101345921LOW QUALITY PROTEIN: C-type lectin domain family 6 member A. (208 aa)
LOC101345665C-type lectin domain family 4 member D isoform X1. (225 aa)
LOC101346433C-type lectin domain family 4 member A-like. (237 aa)
LOC111822114polyubiquitin-C. (77 aa)
LOC101351806Tyrosine-protein kinase. (685 aa)
LOC101347466C-type lectin domain family 4 member C isoform X1. (212 aa)
LOC101347711C-type lectin domain family 4 member A-like. (142 aa)
LOC101361963ubiquitin-60S ribosomal protein L40. (128 aa)
LOC101361706Transcription factor p65. (538 aa)
LOC101342036Mucin-17-like. (984 aa)
LOC101354775Coiled-coil domain-containing protein 71L. (231 aa)
LOC10134953426S proteasome non-ATPase regulatory subunit 12. (456 aa)
LOC10135373626S proteasome regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
LOC101352703Intercellular adhesion molecule 2 isoform X1. (322 aa)
LOC101343418Mitogen-activated protein kinase kinase kinase 14. (947 aa)
LOC101349614Histone acetyltransferase p300. (2422 aa)
LOC101359620Proteasome subunit beta. (277 aa)
LOC101343598Proteasome subunit beta. (239 aa)
LOC101355353NF-kappa-B inhibitor alpha. (314 aa)
LOC101355611Proteasome subunit alpha type. (246 aa)
LOC1013463931-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1267 aa)
LOC10135902426S proteasome non-ATPase regulatory subunit 3. (531 aa)
LOC101344302Caspase-8 isoform X1; Belongs to the peptidase C14A family. (477 aa)
LOC101341837LOW QUALITY PROTEIN: caspase-10; Belongs to the peptidase C14A family. (536 aa)
LOC101348858Proteasome subunit beta. (205 aa)
LOC101343517Mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform X1. (819 aa)
LOC10134887226S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
LOC101351866Nuclear factor NF-kappa-B p105 subunit isoform X1. (997 aa)
LOC101352422Proteasome subunit alpha type. (263 aa)
Your Current Organism:
Trichechus manatus
NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris
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