STRINGSTRING
LOC101360966 LOC101360966 LOC101341907 LOC101341907 LOC101361506 LOC101361506 LOC111819995 LOC111819995 LOC101357710 LOC101357710 LOC101357028 LOC101357028 LOC101347324 LOC101347324 LOC101343574 LOC101343574 LOC101343994 LOC101343994 LOC101357703 LOC101357703 LOC101346283 LOC101346283 LOC111819440 LOC111819440 LOC101341440 LOC101341440 LOC101340624 LOC101340624 LOC111819443 LOC111819443 LOC101342987 LOC101342987 LOC101345697 LOC101345697 LOC101357011 LOC101357011 LOC101340430 LOC101340430 LOC101355318 LOC101355318 LOC101359350 LOC101359350 LOC101356178 LOC101356178 LOC101348314 LOC101348314 LOC101352082 LOC101352082 LOC101352216 LOC101352216 LOC101346187 LOC101346187 LOC101348567 LOC101348567 LOC101340676 LOC101340676 LOC101359588 LOC101359588 LOC105756303 LOC105756303 LOC101343279 LOC101343279 LOC101361619 LOC101361619 LOC101342541 LOC101342541 LOC101340449 LOC101340449 LOC101342744 LOC101342744 LOC101360051 LOC101360051 LOC101356196 LOC101356196 LOC101349004 LOC101349004 LOC105755956 LOC105755956 LOC101354390 LOC101354390 LOC101346801 LOC101346801 LOC101348059 LOC101348059 LOC101347879 LOC101347879 LOC101341783 LOC101341783 LOC101346442 LOC101346442 LOC101349742 LOC101349742 LOC101357163 LOC101357163 LOC101354464 LOC101354464 LOC101345834 LOC101345834 LOC101348552 LOC101348552 LOC101343132 LOC101343132 LOC101360875 LOC101360875 LOC101356833 LOC101356833 LOC101348212 LOC101348212 LOC101355643 LOC101355643 LOC101355475 LOC101355475 LOC101358521 LOC101358521 LOC101353008 LOC101353008 LOC101342874 LOC101342874 LOC101359840 LOC101359840 LOC101342191 LOC101342191 LOC101345483 LOC101345483 LOC101352735 LOC101352735 LOC101340393 LOC101340393 LOC101352558 LOC101352558 LOC101342354 LOC101342354 LOC101356822 LOC101356822 LOC101356744 LOC101356744 LOC101352297 LOC101352297 LOC101343800 LOC101343800 LOC101342187 LOC101342187 LOC101349646 LOC101349646 LOC101361194 LOC101361194 LOC101351345 LOC101351345 LOC101346758 LOC101346758 LOC101349966 LOC101349966 LOC101349898 LOC101349898 LOC101344556 LOC101344556 LOC101347181 LOC101347181 LOC101354276 LOC101354276 LOC101359735 LOC101359735 LOC101343787 LOC101343787 LOC101350574 LOC101350574 LOC101346145 LOC101346145 LOC101350309 LOC101350309 LOC101352540 LOC101352540 LOC101352199 LOC101352199 LOC101356386 LOC101356386 LOC101354339 LOC101354339 LOC101350054 LOC101350054 LOC101343000 LOC101343000 LOC101361512 LOC101361512 LOC101352012 LOC101352012 LOC101349368 LOC101349368 LOC101351290 LOC101351290 LOC101357172 LOC101357172 LOC101342003 LOC101342003 LOC101347499 LOC101347499 LOC101340369 LOC101340369 LOC101357876 LOC101357876 LOC101340507 LOC101340507 LOC101352192 LOC101352192 LOC101356968 LOC101356968 LOC101345281 LOC101345281 LOC101355918 LOC101355918 LOC101340410 LOC101340410 LOC101360762 LOC101360762 LOC101353062 LOC101353062 LOC101355971 LOC101355971 LOC101349963 LOC101349963 LOC101362047 LOC101362047 LOC101357217 LOC101357217 LOC101361627 LOC101361627 LOC101346399 LOC101346399 LOC111821321 LOC111821321 LOC101354182 LOC101354182 LOC101346158 LOC101346158 LOC101340472 LOC101340472 LOC101361453 LOC101361453 LOC101354945 LOC101354945 LOC101359035 LOC101359035 LOC101346329 LOC101346329 LOC101358448 LOC101358448 LOC101348627 LOC101348627 LOC101351100 LOC101351100 LOC101353434 LOC101353434 LOC101347443 LOC101347443 LOC101352744 LOC101352744 LOC101358434 LOC101358434 LOC101351101 LOC101351101 LOC101360432 LOC101360432 LOC101343536 LOC101343536 LOC101361963 LOC101361963 LOC101352140 LOC101352140 LOC111822470 LOC111822470 LOC101345823 LOC101345823 LOC111822114 LOC111822114 LOC101343043 LOC101343043 LOC101360181 LOC101360181 LOC101357323 LOC101357323 LOC101347946 LOC101347946 LOC101340664 LOC101340664 LOC101361555 LOC101361555 LOC101343648 LOC101343648 LOC101353950 LOC101353950 LOC101344750 LOC101344750 LOC101344995 LOC101344995 LOC101346536 LOC101346536 LOC101361258 LOC101361258 LOC101360925 LOC101360925 LOC101361859 LOC101361859 LOC101351144 LOC101351144 LOC101344949 LOC101344949 LOC101351322 LOC101351322 LOC101343767 LOC101343767 LOC101340963 LOC101340963 LOC101341062 LOC101341062 LOC101359012 LOC101359012 LOC101346124 LOC101346124 LOC101346379 LOC101346379 LOC101361501 LOC101361501 LOC101342732 LOC101342732 LOC101347740 LOC101347740 LOC101341296 LOC101341296 LOC101346883 LOC101346883 LOC105755961 LOC105755961 LOC101361983 LOC101361983 LOC101348562 LOC101348562 LOC101347123 LOC101347123 LOC101346698 LOC101346698 LOC101349743 LOC101349743
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101360966Adaptin ear-binding coat-associated protein 1 isoform X1. (275 aa)
LOC101341907Beta-arrestin-2 isoform X1. (452 aa)
LOC101361506LOW QUALITY PROTEIN: uncharacterized protein LOC101361506. (949 aa)
LOC111819995Uncharacterized protein LOC111819995. (388 aa)
LOC101357710Probable G-protein coupled receptor 21; Belongs to the G-protein coupled receptor 1 family. (349 aa)
LOC101357028Multiple C2 and transmembrane domain-containing protein 2 isoform X1. (919 aa)
LOC101347324Dyslexia-associated protein KIAA0319-like protein homolog isoform X1. (1055 aa)
LOC101343574LOW QUALITY PROTEIN: SH3 domain-containing protein 21. (805 aa)
LOC101343994Sorting nexin. (617 aa)
LOC101357703Transferrin receptor protein 1 isoform X1. (834 aa)
LOC101346283Zinc finger FYVE domain-containing protein 1 isoform X1. (779 aa)
LOC111819440Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (124 aa)
LOC101341440Cation-independent mannose-6-phosphate receptor. (2419 aa)
LOC101340624Actin-related protein 3B isoform X3; Belongs to the actin family. (418 aa)
LOC111819443Phosphatidylinositol-binding clathrin assembly protein-like. (175 aa)
LOC101342987Protein phosphatase 1 regulatory subunit 42. (237 aa)
LOC101345697G-protein coupled receptor 52; Belongs to the G-protein coupled receptor 1 family. (361 aa)
LOC101357011Protein kinase C and casein kinase substrate in neurons protein 1 isoform X2. (458 aa)
LOC101340430Epidermal growth factor receptor substrate 15 isoform X1. (724 aa)
LOC101355318Ubiquilin-2 isoform X1. (630 aa)
LOC101359350Vesicle-associated membrane protein 7 isoform X1; Belongs to the synaptobrevin family. (230 aa)
LOC101356178Synaptotagmin-8. (776 aa)
LOC101348314Ubiquilin-3. (654 aa)
LOC101352082Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1851 aa)
LOC101352216Src substrate cortactin. (558 aa)
LOC101346187AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (940 aa)
LOC101348567Ubiquilin-3-like. (521 aa)
LOC101340676Synaptotagmin-9. (470 aa)
LOC101359588LOW QUALITY PROTEIN: ubiquilin-4-like. (578 aa)
LOC105756303Actin-related protein 2. (106 aa)
LOC101343279Dynamin-3 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (869 aa)
LOC101361619Formin-1 isoform X1. (1422 aa)
LOC101342541ralBP1-associated Eps domain-containing protein 1 isoform X1. (796 aa)
LOC101340449GTPase-activating protein and VPS9 domain-containing protein 1 isoform X1. (1459 aa)
LOC101342744Low-density lipoprotein receptor-related protein 2. (4634 aa)
LOC101360051COP9 signalosome complex subunit 1. (245 aa)
LOC101356196Amphiregulin. (254 aa)
LOC101349004Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (371 aa)
LOC105755956NEDD8. (81 aa)
LOC101354390COP9 signalosome complex subunit 7b. (264 aa)
LOC101346801Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1491 aa)
LOC101348059Ubiquilin-like protein. (610 aa)
LOC101347879Synaptotagmin-11. (431 aa)
LOC101341783Vesicular acetylcholine transporter. (532 aa)
LOC101346442Ubiquilin-4. (601 aa)
LOC101349742Protein kinase C and casein kinase substrate in neurons protein 3. (423 aa)
LOC101357163G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (688 aa)
LOC101354464Neuropilin and tolloid-like protein 1. (533 aa)
LOC101345834Disabled homolog 2. (770 aa)
LOC101348552Apolipoprotein B-100. (4488 aa)
LOC101343132arf-GAP domain and FG repeat-containing protein 2. (480 aa)
LOC101360875COP9 signalosome complex subunit 6. (324 aa)
LOC101356833COP9 signalosome complex subunit 2 isoform X1. (450 aa)
LOC101348212Myc box-dependent-interacting protein 1 isoform X3. (594 aa)
LOC101355643Intersectin-1 isoform X1. (1720 aa)
LOC101355475Clathrin coat assembly protein AP180 isoform X1. (907 aa)
LOC101358521Huntingtin-interacting protein 1-related protein. (1068 aa)
LOC101353008T-cell surface glycoprotein CD3 delta chain isoform X1. (172 aa)
LOC101342874E3 ubiquitin-protein ligase CBL isoform X1. (904 aa)
LOC101359840Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
LOC101342191Synaptotagmin-1. (422 aa)
LOC101345483F-BAR domain only protein 1. (879 aa)
LOC101352735Amphiphysin isoform X1. (693 aa)
LOC101340393kxDL motif-containing protein 1. (177 aa)
LOC101352558cyclin-G-associated kinase. (1324 aa)
LOC101342354Vesicle-associated membrane protein 4. (141 aa)
LOC101356822Receptor protein-tyrosine kinase. (1156 aa)
LOC101356744Epigen. (153 aa)
LOC101352297Lysosome membrane protein 2; Belongs to the CD36 family. (478 aa)
LOC101343800Vasopressin-neurophysin 2-copeptin; Belongs to the vasopressin/oxytocin family. (166 aa)
LOC101342187COP9 signalosome complex subunit 4 isoform X1. (406 aa)
LOC101349646Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
LOC101361194Ubiquilin-1 isoform X1. (588 aa)
LOC101351345Caseinolytic peptidase B protein homolog isoform X1. (735 aa)
LOC101346758AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (956 aa)
LOC101349966abscission/NoCut checkpoint regulator. (398 aa)
LOC101349898Sorting nexin-18 isoform X1. (630 aa)
LOC101344556Proheparin-binding EGF-like growth factor. (208 aa)
LOC101347181Epsin-2. (641 aa)
LOC101354276COP9 signalosome complex subunit 3 isoform X1. (423 aa)
LOC101359735Synaptotagmin-4 isoform X1. (425 aa)
LOC101343787Protein kinase C and casein kinase substrate in neurons protein 2. (485 aa)
LOC101350574Signal transducing adapter molecule 1 isoform X1. (540 aa)
LOC101346145Type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
LOC101350309Cdc42-interacting protein 4. (543 aa)
LOC101352540Dynamin-2 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
LOC101352199Epsin-3. (641 aa)
LOC101356386Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa)
LOC101354339Adaptin ear-binding coat-associated protein 2 isoform X1. (263 aa)
LOC101350054Low density lipoprotein receptor adapter protein 1. (309 aa)
LOC101343000Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (300 aa)
LOC101361512Torsin. (333 aa)
LOC101352012Growth arrest-specific protein 7. (446 aa)
LOC101349368Formin-2. (1572 aa)
LOC101351290substance-P receptor; Belongs to the G-protein coupled receptor 1 family. (284 aa)
LOC101357172Uncharacterized protein FLJ45252-like. (394 aa)
LOC101342003Low-density lipoprotein receptor. (866 aa)
LOC101347499Vesicle-associated membrane protein 2 isoform X1. (128 aa)
LOC101340369F-BAR domain only protein 2. (806 aa)
LOC101357876Ubiquitin-like protein 7 isoform X1. (397 aa)
LOC101340507AP2-associated protein kinase 1. (964 aa)
LOC101352192Signal transducing adapter molecule 2 isoform X1. (550 aa)
LOC101356968Intersectin-2 isoform X4. (1687 aa)
LOC101345281Formin-binding protein 1. (647 aa)
LOC101355918Protransforming growth factor alpha isoform X1. (162 aa)
LOC101340410Clathrin heavy chain linker domain-containing protein 1. (483 aa)
LOC101360762endophilin-A2 isoform X1. (402 aa)
LOC101353062LOW QUALITY PROTEIN: arrestin-C. (356 aa)
LOC101355971Pro-epidermal growth factor. (1109 aa)
LOC101349963Inositol polyphosphate 5-phosphatase OCRL-1. (744 aa)
LOC101362047Epsin-1. (575 aa)
LOC101357217Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma. (703 aa)
LOC101361627AP-2 complex subunit mu isoform X1; Belongs to the adaptor complexes medium subunit family. (435 aa)
LOC101346399Formin-binding protein 1-like. (609 aa)
LOC111821321Uncharacterized protein LOC111821321. (115 aa)
LOC101354182Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (207 aa)
LOC101346158Proepiregulin. (98 aa)
LOC101340472AP-2 complex subunit sigma isoform X1. (172 aa)
LOC101361453SH3 domain-containing kinase-binding protein 1 isoform X6. (713 aa)
LOC101354945Beta-arrestin-1. (395 aa)
LOC101359035Huntingtin-interacting protein 1 isoform X1. (1021 aa)
LOC101346329G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (686 aa)
LOC101358448Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform X1; Belongs to the PI3/PI4-kinase family. (1688 aa)
LOC101348627BMP-2-inducible protein kinase isoform X1. (1134 aa)
LOC101351100Interleukin-7 receptor subunit alpha isoform X1. (480 aa)
LOC101353434arf-GAP domain and FG repeat-containing protein 1 isoform X1. (579 aa)
LOC101347443ralBP1-associated Eps domain-containing protein 2. (614 aa)
LOC101352744T-cell surface glycoprotein CD3 gamma chain isoform X1. (180 aa)
LOC101358434COP9 signalosome complex subunit 8 isoform X1. (214 aa)
LOC101351101AP complex subunit beta. (951 aa)
LOC101360432Probetacellulin. (181 aa)
LOC101343536LOW QUALITY PROTEIN: dyslexia-associated protein KIAA0319 homolog. (1027 aa)
LOC101361963ubiquitin-60S ribosomal protein L40. (128 aa)
LOC101352140Epidermal growth factor receptor substrate 15-like 1. (804 aa)
LOC111822470piggyBac transposable element-derived protein 4. (604 aa)
LOC101345823Vesicle-associated membrane protein 3. (111 aa)
LOC111822114polyubiquitin-C. (77 aa)
LOC101343043Stonin-2 isoform X1; Belongs to the Stoned B family. (769 aa)
LOC101360181Synaptojanin-1. (1068 aa)
LOC101357323Phosphatidylinositol-binding clathrin assembly protein isoform X1. (678 aa)
LOC101347946LMBR1 domain-containing protein 2 isoform X1. (694 aa)
LOC101340664Cation-dependent mannose-6-phosphate receptor isoform X1. (310 aa)
LOC101361555Neural Wiskott-Aldrich syndrome protein. (408 aa)
LOC101343648T-cell surface glycoprotein CD4 isoform X1. (488 aa)
LOC101353950COP9 signalosome complex subunit 7a. (275 aa)
LOC101344750Vesicle-associated membrane protein 5 isoform X1. (182 aa)
LOC101344995Vesicle-associated membrane protein 8. (101 aa)
LOC101346536trans-Golgi network integral membrane protein 2 isoform X1. (284 aa)
LOC101361258Torsin. (336 aa)
LOC101360925Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
LOC101361859Synaptotagmin-2. (422 aa)
LOC101351144Dynamin-1 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (864 aa)
LOC101344949Solute carrier family 2, facilitated glucose transporter member 8; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (478 aa)
LOC101351322Multiple C2 and transmembrane domain-containing protein 1 isoform X1. (1000 aa)
LOC101343767Actin-related protein 3 isoform X1; Belongs to the actin family. (418 aa)
LOC101340963Sorting nexin. (574 aa)
LOC101341062Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (820 aa)
LOC101359012Growth factor receptor-bound protein 2. (176 aa)
LOC101346124ENTH domain-containing protein 1. (611 aa)
LOC101346379endophilin-A1. (352 aa)
LOC101361501Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
LOC101342732COP9 signalosome complex subunit 5. (334 aa)
LOC101347740Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (218 aa)
LOC101341296endophilin-A3 isoform X1. (347 aa)
LOC101346883Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (211 aa)
LOC105755961Stonin-1; Belongs to the Stoned B family. (733 aa)
LOC101361983ubiquitin-40S ribosomal protein S27a. (156 aa)
LOC101348562SH3-containing GRB2-like protein 3-interacting protein 1 isoform X1. (834 aa)
LOC101347123Putative tyrosine-protein phosphatase auxilin isoform X1. (974 aa)
LOC101346698Synaptojanin-2. (1504 aa)
LOC101349743Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (168 aa)
Your Current Organism:
Trichechus manatus
NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris
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