75 items (Trichechus manatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101342428	Dedicator of cytokinesis protein 5; Belongs to the DOCK family. (1843 aa)
	LOC101344591	Engulfment and cell motility protein 2 isoform X1. (720 aa)
	LOC101353271	Guanine nucleotide exchange factor VAV3 isoform X1. (850 aa)
	LOC101360881	Integrin beta; Belongs to the integrin beta chain family. (832 aa)
	LOC101345823	Vesicle-associated membrane protein 3. (111 aa)
	LOC101352217	Triple functional domain protein. (3059 aa)
	LOC101341943	MAGUK p55 subfamily member 7; Belongs to the MAGUK family. (576 aa)
	LOC101343275	Guanine nucleotide exchange factor DBS isoform X7. (1190 aa)
	LOC101351120	Serine/threonine-protein kinase VRK2. (617 aa)
	LOC101340392	Mitogen-activated protein kinase kinase kinase 11. (622 aa)
	LOC101348449	Rho-related GTP-binding protein RhoG. (191 aa)
	LOC101344724	Protein ERGIC-53 isoform X2. (510 aa)
	LOC101359386	Dedicator of cytokinesis protein 4; Belongs to the DOCK family. (1961 aa)
	LOC101344398	Inner nuclear membrane protein Man1 isoform X1. (942 aa)
	LOC101353760	Rho GTPase-activating protein 21 isoform X1. (1947 aa)
	LOC101353559	lamin-B receptor isoform X1. (499 aa)
	LOC101347509	Proto-oncogene vav. (841 aa)
	LOC101356962	Dedicator of cytokinesis protein 1; Belongs to the DOCK family. (1865 aa)
	LOC101349616	Erbin isoform X1. (1460 aa)
	LOC101355178	Non-specific serine/threonine protein kinase. (524 aa)
	LOC101361679	Kalirin isoform X3. (2358 aa)
	LOC101357703	Transferrin receptor protein 1 isoform X1. (834 aa)
	LOC101347730	Kinectin isoform X1. (1345 aa)
	LOC101352953	Pleckstrin homology domain-containing family G member 3 isoform X2. (1220 aa)
	LOC101343759	LOW QUALITY PROTEIN: cytoplasmic FMR1-interacting protein 1. (1399 aa)
	LOC101353444	Rho GTPase-activating protein 39. (1133 aa)
	LOC101361023	Proto-oncogene DBL. (997 aa)
	LOC101358909	Mitogen-activated protein kinase kinase kinase. (910 aa)
	LOC101340742	Mitochondrial proton/calcium exchanger protein isoform X1. (719 aa)
	LOC101341677	LETM1 domain-containing protein LETM2, mitochondrial isoform X1. (492 aa)
	LOC101340830	Rho GTPase-activating protein 32 isoform X2. (2101 aa)
	LOC101345007	LOW QUALITY PROTEIN: probable RNA-binding protein 23. (456 aa)
	LOC101343833	Emerin. (260 aa)
	LOC101349166	Membrane-associated progesterone receptor component 2; Belongs to the cytochrome b5 family. (247 aa)
	LOC101345849	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
	LOC101354226	Basal cell adhesion molecule. (588 aa)
	LOC101343550	Guanine nucleotide exchange factor VAV2. (839 aa)
	LOC101355560	NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial; Belongs to the complex I 30 kDa subunit family. (261 aa)
	LOC101342704	Rho GDP-dissociation inhibitor 2. (200 aa)
	LOC101347213	Rho GTPase-activating protein 1 isoform X1. (439 aa)
	LOC101355643	Intersectin-1 isoform X1. (1720 aa)
	LOC101362071	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5. (94 aa)
	LOC101347111	Synaptobrevin homolog YKT6; Belongs to the synaptobrevin family. (198 aa)
	LOC101342621	Cell surface glycoprotein MUC18. (651 aa)
	LOC101346943	Ankyrin repeat and LEM domain-containing protein 2 isoform X1. (969 aa)
	LOC101361633	Syntaxin-5 isoform X1; Belongs to the syntaxin family. (355 aa)
	LOC101347530	Rho guanine nucleotide exchange factor 16. (703 aa)
	LOC101352041	Starch-binding domain-containing protein 1. (359 aa)
	LOC101355456	LOW QUALITY PROTEIN: probable guanine nucleotide exchange factor MCF2L2. (1278 aa)
	LOC101354281	Rho guanine nucleotide exchange factor 5. (1605 aa)
	LOC101350320	Ragulator complex protein LAMTOR1. (161 aa)
	LOC101340735	Rho GTPase-activating protein 35. (1501 aa)
	LOC101341495	Vang-like protein. (524 aa)
	LOC101351692	Oligophrenin-1. (803 aa)
	LOC101353498	Extended synaptotagmin-1. (1104 aa)
	LOC101343350	ADP-ribosylation factor GTPase-activating protein 3 isoform X1. (517 aa)
	LOC101361102	Rho guanine nucleotide exchange factor 26 isoform X1. (863 aa)
	LOC101355264	Ephrin type-A receptor 2. (977 aa)
	LOC101361943	Cell division control protein 42 homolog isoform X1. (191 aa)
	LOC101360492	Rho GTPase-activating protein 5. (1503 aa)
	LOC101353803	MAGUK p55 subfamily member 3; Belongs to the MAGUK family. (609 aa)
	LOC101356867	DEP domain-containing protein 1B isoform X1. (502 aa)
	LOC101347746	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
	LOC101341470	Rho GDP-dissociation inhibitor 1. (252 aa)
	LOC101356864	Cdc42 effector protein 1. (358 aa)
	LOC101349016	Mitogen-activated protein kinase kinase kinase 21. (815 aa)
	LOC101346469	Rho GDP-dissociation inhibitor 3. (199 aa)
	LOC101342980	Uncharacterized protein KIAA0355 homolog. (1070 aa)
	LOC101343482	Mitogen-activated protein kinase kinase kinase 9 isoform X1. (1116 aa)
	LOC101357939	Dedicator of cytokinesis protein 2 isoform X1; Belongs to the DOCK family. (1829 aa)
	LOC101349168	Vesicle-associated membrane protein-associated protein B/C. (243 aa)
	LOC101348913	RNA-binding protein 39 isoform X1. (530 aa)
	LOC101356171	Serine/threonine-protein kinase TNNI3K. (853 aa)
	LOC101345668	Dedicator of cytokinesis protein 3; Belongs to the DOCK family. (2039 aa)
	LOC101346179	Ras-related protein Rab-7a. (207 aa)

Your Current Organism:

Trichechus manatus

NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101340392	LOC101348449	A0A2Y9RFB0	A0A2Y9RCZ1	Mitogen-activated protein kinase kinase kinase 11.	Rho-related GTP-binding protein RhoG.	0.554
LOC101340392	LOC101361943	A0A2Y9RFB0	A0A2Y9DM65	Mitogen-activated protein kinase kinase kinase 11.	Cell division control protein 42 homolog isoform X1.	0.973
LOC101340735	LOC101348449	A0A2Y9DUX7	A0A2Y9RCZ1	Rho GTPase-activating protein 35.	Rho-related GTP-binding protein RhoG.	0.506
LOC101340735	LOC101360492	A0A2Y9DUX7	A0A2Y9DL70	Rho GTPase-activating protein 35.	Rho GTPase-activating protein 5.	0.900
LOC101340735	LOC101361943	A0A2Y9DUX7	A0A2Y9DM65	Rho GTPase-activating protein 35.	Cell division control protein 42 homolog isoform X1.	0.598
LOC101340742	LOC101348449	A0A2Y9G1L6	A0A2Y9RCZ1	Mitochondrial proton/calcium exchanger protein isoform X1.	Rho-related GTP-binding protein RhoG.	0.447
LOC101340830	LOC101348449	A0A2Y9G156	A0A2Y9RCZ1	Rho GTPase-activating protein 32 isoform X2.	Rho-related GTP-binding protein RhoG.	0.536
LOC101340830	LOC101355643	A0A2Y9G156	A0A2Y9E4Y4	Rho GTPase-activating protein 32 isoform X2.	Intersectin-1 isoform X1.	0.522
LOC101340830	LOC101361943	A0A2Y9G156	A0A2Y9DM65	Rho GTPase-activating protein 32 isoform X2.	Cell division control protein 42 homolog isoform X1.	0.683
LOC101341470	LOC101342704	A0A2Y9DGW0	A0A2Y9E6M5	Rho GDP-dissociation inhibitor 1.	Rho GDP-dissociation inhibitor 2.	0.901
LOC101341470	LOC101346469	A0A2Y9DGW0	A0A2Y9DEL9	Rho GDP-dissociation inhibitor 1.	Rho GDP-dissociation inhibitor 3.	0.915
LOC101341470	LOC101348449	A0A2Y9DGW0	A0A2Y9RCZ1	Rho GDP-dissociation inhibitor 1.	Rho-related GTP-binding protein RhoG.	0.707
LOC101341470	LOC101361943	A0A2Y9DGW0	A0A2Y9DM65	Rho GDP-dissociation inhibitor 1.	Cell division control protein 42 homolog isoform X1.	0.838
LOC101341495	LOC101341943	A0A2Y9DTR1	A0A2Y9RPB0	Vang-like protein.	MAGUK p55 subfamily member 7; Belongs to the MAGUK family.	0.456
LOC101341495	LOC101348449	A0A2Y9DTR1	A0A2Y9RCZ1	Vang-like protein.	Rho-related GTP-binding protein RhoG.	0.506
LOC101341495	LOC101349616	A0A2Y9DTR1	A0A2Y9R123	Vang-like protein.	Erbin isoform X1.	0.405
LOC101341495	LOC101353803	A0A2Y9DTR1	A0A2Y9DHT1	Vang-like protein.	MAGUK p55 subfamily member 3; Belongs to the MAGUK family.	0.456
LOC101341495	LOC101361943	A0A2Y9DTR1	A0A2Y9DM65	Vang-like protein.	Cell division control protein 42 homolog isoform X1.	0.460
LOC101341677	LOC101348449	A0A2Y9G1K1	A0A2Y9RCZ1	LETM1 domain-containing protein LETM2, mitochondrial isoform X1.	Rho-related GTP-binding protein RhoG.	0.447
LOC101341943	LOC101341495	A0A2Y9RPB0	A0A2Y9DTR1	MAGUK p55 subfamily member 7; Belongs to the MAGUK family.	Vang-like protein.	0.456