STRINGSTRING
LOC101347544 LOC101347544 LOC101346179 LOC101346179 LOC101357840 LOC101357840 LOC101343995 LOC101343995 LOC101360368 LOC101360368 LOC101342638 LOC101342638 LOC101345760 LOC101345760 LOC101341374 LOC101341374 LOC101355243 LOC101355243 LOC101346361 LOC101346361 LOC101355570 LOC101355570 LOC101359341 LOC101359341 LOC101347136 LOC101347136 LOC101351035 LOC101351035 LOC101358995 LOC101358995 LOC101358131 LOC101358131 LOC101342824 LOC101342824 LOC101353040 LOC101353040 LOC101347656 LOC101347656 LOC101345874 LOC101345874 LOC101352446 LOC101352446 LOC101350547 LOC101350547 LOC101347746 LOC101347746 LOC101343332 LOC101343332 LOC101346216 LOC101346216 LOC101343861 LOC101343861 LOC101359453 LOC101359453 LOC101355263 LOC101355263 LOC101360493 LOC101360493 LOC101354510 LOC101354510 LOC101355699 LOC101355699 LOC101341838 LOC101341838 LOC101355870 LOC101355870 LOC101356130 LOC101356130 LOC101341078 LOC101341078 LOC101354514 LOC101354514 LOC101343706 LOC101343706 LOC101347007 LOC101347007 LOC101350401 LOC101350401 LOC101355195 LOC101355195 LOC101349296 LOC101349296 LOC101344230 LOC101344230 LOC101344970 LOC101344970 LOC101349459 LOC101349459 LOC101345047 LOC101345047 LOC101357647 LOC101357647 LOC101349553 LOC101349553 LOC101345383 LOC101345383 LOC101361883 LOC101361883 LOC101341172 LOC101341172 LOC101345725 LOC101345725 LOC101358419 LOC101358419 LOC101343535 LOC101343535 LOC101358337 LOC101358337 LOC101347525 LOC101347525 LOC101342109 LOC101342109 LOC101346849 LOC101346849 LOC101355630 LOC101355630 LOC101343808 LOC101343808 LOC101343804 LOC101343804 LOC101350333 LOC101350333 LOC101353683 LOC101353683 LOC101356256 LOC101356256 LOC101346525 LOC101346525 LOC101351272 LOC101351272 LOC101340589 LOC101340589 LOC101362072 LOC101362072 LOC101351010 LOC101351010 LOC101351891 LOC101351891 LOC101347875 LOC101347875 LOC101350849 LOC101350849 LOC101348812 LOC101348812 LOC101346094 LOC101346094 LOC101346448 LOC101346448 LOC101346705 LOC101346705 LOC101350174 LOC101350174 LOC101356603 LOC101356603 LOC101351734 LOC101351734 LOC101349773 LOC101349773 LOC101342812 LOC101342812 LOC101360558 LOC101360558 LOC101356099 LOC101356099 LOC101349952 LOC101349952 LOC101346894 LOC101346894 LOC105756211 LOC105756211 LOC101356151 LOC101356151 LOC101345051 LOC101345051 LOC101343546 LOC101343546 LOC101346784 LOC101346784 LOC101348995 LOC101348995 LOC101359695 LOC101359695 LOC101356436 LOC101356436 LOC101342804 LOC101342804 LOC101357622 LOC101357622 LOC101343081 LOC101343081 LOC101355651 LOC101355651 LOC101359690 LOC101359690 LOC101359268 LOC101359268 LOC101346283 LOC101346283 LOC101347417 LOC101347417 LOC101357548 LOC101357548 LOC101356794 LOC101356794 LOC101361176 LOC101361176 LOC101351212 LOC101351212 LOC101355333 LOC101355333 LOC101348349 LOC101348349 LOC101360739 LOC101360739 LOC101350197 LOC101350197 LOC101349796 LOC101349796 LOC101343242 LOC101343242 LOC101347848 LOC101347848 LOC101343780 LOC101343780 LOC101345298 LOC101345298 LOC101359288 LOC101359288 LOC101345902 LOC101345902 LOC101360675 LOC101360675 LOC101359379 LOC101359379 LOC101355872 LOC101355872 LOC101352467 LOC101352467 LOC101358678 LOC101358678 LOC101346534 LOC101346534 LOC101354889 LOC101354889 LOC101352468 LOC101352468 LOC101344056 LOC101344056 LOC101345331 LOC101345331 LOC101359658 LOC101359658 LOC101345299 LOC101345299 LOC101345300 LOC101345300 LOC101345997 LOC101345997 LOC101357581 LOC101357581 LOC101352047 LOC101352047 LOC111821969 LOC111821969 LOC101358526 LOC101358526 LOC105756546 LOC105756546 LOC101345486 LOC101345486 LOC101345407 LOC101345407 LOC101346865 LOC101346865 LOC101344995 LOC101344995
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101347544Myotubularin-related protein 14 isoform X3. (649 aa)
LOC101346179Ras-related protein Rab-7a. (207 aa)
LOC101357840RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
LOC101343995Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (458 aa)
LOC101360368Non-specific serine/threonine protein kinase. (552 aa)
LOC101342638cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (398 aa)
LOC101345760Ras-related protein Rab-1A. (205 aa)
LOC101341374Nuclear receptor-binding factor 2. (288 aa)
LOC101355243Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
LOC101346361Bcl-2-like protein 1 isoform X1. (233 aa)
LOC101355570Tumor protein p53-inducible nuclear protein 2. (221 aa)
LOC101359341Beclin 1-associated autophagy-related key regulator. (492 aa)
LOC101347136Hypoxia-inducible factor 1-alpha isoform X1. (823 aa)
LOC101351035Phosphatidylinositol 3-kinase regulatory subunit gamma. (462 aa)
LOC101358995Ras-related GTP-binding protein C isoform X1. (399 aa)
LOC101358131Tuberin. (1813 aa)
LOC101342824DEP domain-containing mTOR-interacting protein. (409 aa)
LOC1013530403-phosphoinositide-dependent protein kinase 1. (636 aa)
LOC101347656Ras-related GTP-binding protein A. (313 aa)
LOC101345874WD repeat domain phosphoinositide-interacting protein 1 isoform X1. (446 aa)
LOC101352446Serine/threonine-protein kinase/endoribonuclease IRE1. (976 aa)
LOC101350547Ubiquitin-like-conjugating enzyme ATG10. (220 aa)
LOC101347746Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
LOC101343332Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
LOC101346216Ras-related protein Rab-7b isoform X1. (200 aa)
LOC101343861BCL2/adenovirus E1B 19 kDa protein-interacting protein 3. (194 aa)
LOC101359453Gamma-aminobutyric acid receptor-associated protein. (117 aa)
LOC101355263Autophagy-related protein 2 homolog B. (2078 aa)
LOC101360493Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
LOC101354510Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
LOC101355699Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (473 aa)
LOC101341838Death-associated protein kinase 3; Belongs to the protein kinase superfamily. (454 aa)
LOC101355870Vacuole membrane protein 1. (406 aa)
LOC101356130endophilin-B1 isoform X2. (394 aa)
LOC101341078Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
LOC101354514Serine/threonine-protein kinase STK11; Belongs to the protein kinase superfamily. (439 aa)
LOC101343706Lysosome-associated membrane glycoprotein 2 isoform X1. (413 aa)
LOC101347007Apoptosis regulator Bcl-2 isoform X1. (229 aa)
LOC101350401Insulin receptor substrate 4 isoform X1. (1267 aa)
LOC101355195Immunoglobulin-binding protein 1 isoform X1. (405 aa)
LOC101349296Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (398 aa)
LOC101344230GTPase NRas isoform X1. (189 aa)
LOC101344970eIF-2-alpha kinase GCN2 isoform X1. (1649 aa)
LOC101349459Guanine nucleotide exchange protein SMCR8. (938 aa)
LOC101345047Cathepsin L1; Belongs to the peptidase C1 family. (334 aa)
LOC101357647Ras-related protein M-Ras isoform X1. (208 aa)
LOC101349553Ras-related protein R-Ras. (218 aa)
LOC101345383Serine/threonine-protein kinase ULK2 isoform X1. (1038 aa)
LOC101361883UV radiation resistance-associated gene protein. (700 aa)
LOC101341172Cathepsin B isoform X1; Belongs to the peptidase C1 family. (340 aa)
LOC101345725Phosphoinositide 3-kinase regulatory subunit 4 isoform X1. (1358 aa)
LOC101358419DNA damage-inducible transcript 4 protein. (232 aa)
LOC101343535Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (482 aa)
LOC101358337Serine/threonine-protein phosphatase. (309 aa)
LOC101347525GTPase KRas isoform X3. (227 aa)
LOC101342109Cathepsin L1; Belongs to the peptidase C1 family. (339 aa)
LOC101346849Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC101355630High mobility group protein B1. (215 aa)
LOC101343808Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
LOC101343804Phosphatidylinositol 3-kinase regulatory subunit beta. (729 aa)
LOC101350333Serine/threonine-protein phosphatase. (309 aa)
LOC101353683Ras-related protein Rab-8A. (207 aa)
LOC101356256Synaptosomal-associated protein 29. (253 aa)
LOC101346525Gamma-aminobutyric acid receptor-associated protein-like 1. (117 aa)
LOC101351272Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (393 aa)
LOC101340589Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (377 aa)
LOC101362072Insulin receptor substrate 1-like. (535 aa)
LOC101351010Sequestosome-1 isoform X1. (440 aa)
LOC101351891RB1-inducible coiled-coil protein 1 isoform X1. (1592 aa)
LOC101347875Gamma-aminobutyric acid receptor-associated protein-like 2. (117 aa)
LOC101350849Guanine nucleotide exchange C9orf72 homolog isoform X1. (481 aa)
LOC101348812Ras-related GTP-binding protein D isoform X1. (397 aa)
LOC101346094Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
LOC101346448Cathepsin D; Belongs to the peptidase A1 family. (409 aa)
LOC101346705Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (106 aa)
LOC101350174Autophagy-related protein 16-1 isoform X1. (607 aa)
LOC101356603Ras-related GTP-binding protein B isoform X1. (374 aa)
LOC101351734Mitogen-activated protein kinase. (464 aa)
LOC101349773Ras-related protein Rab-7a-like. (196 aa)
LOC101342812Eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1. (1113 aa)
LOC101360558Ras-related protein Rab-39B. (213 aa)
LOC101356099Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
LOC101349952LOW QUALITY PROTEIN: beclin-2. (363 aa)
LOC101346894Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (940 aa)
LOC105756211Proline-rich acidic protein 1. (179 aa)
LOC101356151Insulin receptor substrate 1. (1236 aa)
LOC101345051Insulin receptor substrate 2. (1311 aa)
LOC101343546Mitogen-activated protein kinase. (427 aa)
LOC101346784Non-specific serine/threonine protein kinase. (565 aa)
LOC101348995cAMP-dependent protein kinase catalytic subunit alpha. (293 aa)
LOC101359695Syntaxin-17; Belongs to the syntaxin family. (302 aa)
LOC101356436Eukaryotic translation initiation factor 2 subunit 1. (315 aa)
LOC101342804GTPase HRas isoform X1. (189 aa)
LOC101357622Autophagy-related protein 3. (318 aa)
LOC101343081LOW QUALITY PROTEIN: regulatory-associated protein of mTOR. (1718 aa)
LOC101355651Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa)
LOC101359690Beclin-1 isoform X1. (448 aa)
LOC101359268Target of rapamycin complex subunit LST8 isoform X1. (326 aa)
LOC101346283Zinc finger FYVE domain-containing protein 1 isoform X1. (779 aa)
LOC101347417Hamartin isoform X1. (1160 aa)
LOC101357548Death-associated protein kinase 2; Belongs to the protein kinase superfamily. (476 aa)
LOC101356794WD repeat-containing protein 41. (459 aa)
LOC101361176TRAF family member-associated NF-kappa-B activator isoform X1. (421 aa)
LOC101351212Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
LOC101355333Tyrosine-protein kinase receptor. (1173 aa)
LOC101348349Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
LOC101360739GTP-binding protein Rheb isoform X1. (185 aa)
LOC101350197Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (393 aa)
LOC101349796Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (839 aa)
LOC101343242Run domain Beclin-1-interacting and cysteine-rich domain-containing protein. (924 aa)
LOC101347848LOW QUALITY PROTEIN: calcium/calmodulin-dependent protein kinase kinase 2. (548 aa)
LOC101343780CASP8 and FADD-like apoptosis regulator isoform X1; Belongs to the peptidase C14A family. (510 aa)
LOC101345298Phosphatidylinositol 3-kinase catalytic subunit type 3. (914 aa)
LOC101359288Myotubularin-related protein 3 isoform X1. (1247 aa)
LOC101345902Serine/threonine-protein kinase TBK1 isoform X1. (758 aa)
LOC101360675Myotubularin-related protein 4 isoform X1. (1211 aa)
LOC101359379WD repeat domain phosphoinositide-interacting protein 2 isoform X1. (445 aa)
LOC101355872Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (720 aa)
LOC101352467Death-associated protein kinase 1. (1271 aa)
LOC101358678Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1082 aa)
LOC101346534Inositol 1,4,5-trisphosphate receptor type 1. (2715 aa)
LOC101354889Ras-related protein R-Ras2. (169 aa)
LOC101352468Autophagy-related protein 16-2 isoform X1. (623 aa)
LOC101344056Lysosome-associated membrane glycoprotein 1 isoform X1. (416 aa)
LOC101345331TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
LOC101359658Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
LOC101345299Cathepsin L1-like; Belongs to the peptidase C1 family. (334 aa)
LOC101345300LOW QUALITY PROTEIN: proline-rich AKT1 substrate 1. (351 aa)
LOC101345997Autophagy-related protein 2 homolog A. (1926 aa)
LOC101357581Serine/threonine-protein kinase ULK1. (1323 aa)
LOC101352047Bcl2-associated agonist of cell death. (167 aa)
LOC111821969LOW QUALITY PROTEIN: eIF-2-alpha kinase GCN2-like. (1121 aa)
LOC101358526Mitogen-activated protein kinase 1. (263 aa)
LOC105756546Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (728 aa)
LOC101345486Ras-related protein Rab-33B isoform X1. (242 aa)
LOC101345407Activating molecule in BECN1-regulated autophagy protein 1 isoform X1. (1299 aa)
LOC101346865Autophagy-related protein 101. (218 aa)
LOC101344995Vesicle-associated membrane protein 8. (101 aa)
Your Current Organism:
Trichechus manatus
NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris
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