56 items (Trichechus manatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101357840	RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
	LOC101346344	MAP kinase-activated protein kinase 3 isoform X1; Belongs to the protein kinase superfamily. (384 aa)
	LOC101351035	Phosphatidylinositol 3-kinase regulatory subunit gamma. (462 aa)
	LOC101355330	Calcineurin subunit B type 2. (170 aa)
	LOC101345018	Prostaglandin G/H synthase 2. (604 aa)
	LOC101356454	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
	LOC101355428	Ras-related C3 botulinum toxin substrate 2 isoform X1. (192 aa)
	LOC101348250	Protein kinase C alpha type isoform X2. (549 aa)
	LOC101360313	Ras-related C3 botulinum toxin substrate 3. (188 aa)
	LOC101347746	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
	LOC101349439	Sphingosine kinase 1. (471 aa)
	LOC101343332	Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
	LOC101342996	MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (400 aa)
	LOC101361943	Cell division control protein 42 homolog isoform X1. (191 aa)
	LOC101360493	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	LOC101346393	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1267 aa)
	LOC101359726	SHC-transforming protein 2. (428 aa)
	LOC101341078	Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
	LOC101361614	Mitogen-activated protein kinase. (283 aa)
	LOC101361872	Mitogen-activated protein kinase. (366 aa)
	LOC101344230	GTPase NRas isoform X1. (189 aa)
	LOC101352466	Mitogen-activated protein kinase. (595 aa)
	LOC101353066	Phospholipase A2. (818 aa)
	LOC101355199	Phospholipase A2. (850 aa)
	LOC101352550	Phospholipase A2. (784 aa)
	LOC101354943	Phospholipase A2. (863 aa)
	LOC101351254	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
	LOC101348626	Vascular endothelial growth factor receptor 2 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
	LOC101347525	GTPase KRas isoform X3. (227 aa)
	LOC101346849	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	LOC101343804	Phosphatidylinositol 3-kinase regulatory subunit beta. (729 aa)
	LOC101340589	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (377 aa)
	LOC101345916	Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family. (209 aa)
	LOC101356099	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
	LOC101353424	Serine/threonine-protein phosphatase. (525 aa)
	LOC101342555	Tyrosine-protein kinase. (542 aa)
	LOC101359597	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
	LOC101342804	GTPase HRas isoform X1. (189 aa)
	LOC101356953	Nitric oxide synthase; Produces nitric oxide (NO). (1214 aa)
	LOC101345270	Phospholipase A2. (757 aa)
	LOC101350197	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (393 aa)
	LOC101341920	Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (637 aa)
	LOC101356054	Ras-related C3 botulinum toxin substrate 1. (148 aa)
	LOC101347350	Mitogen-activated protein kinase. (321 aa)
	LOC101355103	Caspase-9; Belongs to the peptidase C14A family. (448 aa)
	LOC101358678	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1082 aa)
	LOC101343394	Calcineurin subunit B type 1 isoform X1. (170 aa)
	LOC101357894	Serine/threonine-protein phosphatase. (511 aa)
	LOC101347440	Serine/threonine-protein phosphatase. (418 aa)
	LOC101359658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
	LOC101357482	Sphingosine kinase 2. (651 aa)
	LOC101352047	Bcl2-associated agonist of cell death. (167 aa)
	LOC101351714	Focal adhesion kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
	LOC101358526	Mitogen-activated protein kinase 1. (263 aa)
	LOC101359851	SH2 domain-containing protein 2A. (437 aa)
	LOC101355751	Nuclear factor of activated T-cells, cytoplasmic 2 isoform X1. (930 aa)

Your Current Organism:

Trichechus manatus

NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101340589	LOC101341078	A0A2Y9E433	A0A2Y9DQ05	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily.	0.972
LOC101340589	LOC101342555	A0A2Y9E433	A0A2Y9G0M3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Tyrosine-protein kinase.	0.526
LOC101340589	LOC101342804	A0A2Y9E433	A0A2Y9QL66	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	GTPase HRas isoform X1.	0.937
LOC101340589	LOC101342996	A0A2Y9E433	A0A2Y9DII9	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily.	0.695
LOC101340589	LOC101343332	A0A2Y9E433	A0A2Y9DHL4	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.	0.972
LOC101340589	LOC101344230	A0A2Y9E433	A0A2Y9DST5	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	GTPase NRas isoform X1.	0.937
LOC101340589	LOC101345270	A0A2Y9E433	A0A2Y9QRA0	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Phospholipase A2.	0.965
LOC101340589	LOC101346344	A0A2Y9E433	A0A2Y9D6E8	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	MAP kinase-activated protein kinase 3 isoform X1; Belongs to the protein kinase superfamily.	0.693
LOC101340589	LOC101347350	A0A2Y9E433	A0A2Y9R6Y7	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase.	0.948
LOC101340589	LOC101347525	A0A2Y9E433	A0A2Y9DZS8	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	GTPase KRas isoform X3.	0.937
LOC101340589	LOC101348250	A0A2Y9E433	A0A2Y9DGJ5	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Protein kinase C alpha type isoform X2.	0.919
LOC101340589	LOC101349439	A0A2Y9E433	A0A2Y9DHH7	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Sphingosine kinase 1.	0.908
LOC101340589	LOC101350197	A0A2Y9E433	A0A2Y9QX25	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.933
LOC101340589	LOC101351254	A0A2Y9E433	A0A2Y9DWD1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.909
LOC101340589	LOC101352047	A0A2Y9E433	A0A2Y9RPZ9	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Bcl2-associated agonist of cell death.	0.904
LOC101340589	LOC101352466	A0A2Y9E433	A0A2Y9DT27	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase.	0.936
LOC101340589	LOC101352550	A0A2Y9E433	A0A2Y9DTI2	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Phospholipase A2.	0.925
LOC101340589	LOC101353066	A0A2Y9E433	A0A2Y9DTA8	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Phospholipase A2.	0.926
LOC101340589	LOC101354943	A0A2Y9E433	A0A2Y9DUF8	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Phospholipase A2.	0.925
LOC101340589	LOC101355103	A0A2Y9E433	A0A2Y9R8L3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Caspase-9; Belongs to the peptidase C14A family.	0.497