STRINGSTRING
LOC101356840 LOC101356840 LOC101357085 LOC101357085 LOC101355396 LOC101355396 LOC101345929 LOC101345929 LOC101347717 LOC101347717 LOC101346612 LOC101346612 LOC101361653 LOC101361653 LOC101360368 LOC101360368 LOC101342638 LOC101342638 LOC101349247 LOC101349247 LOC101346277 LOC101346277 LOC101357856 LOC101357856 LOC101359687 LOC101359687 LOC101357690 LOC101357690 LOC101347064 LOC101347064 LOC101349513 LOC101349513 LOC101349430 LOC101349430 LOC101341147 LOC101341147 LOC101361504 LOC101361504 LOC101361759 LOC101361759 LOC101347833 LOC101347833 LOC101340810 LOC101340810 LOC101355948 LOC101355948 LOC101344372 LOC101344372 LOC101343767 LOC101343767 LOC101358927 LOC101358927 LOC101350966 LOC101350966 LOC101341480 LOC101341480 LOC101361943 LOC101361943 LOC101345888 LOC101345888 LOC101346746 LOC101346746 LOC101352716 LOC101352716 LOC101354844 LOC101354844 LOC101354514 LOC101354514 LOC101351770 LOC101351770 LOC101342844 LOC101342844 LOC101353246 LOC101353246 LOC101356558 LOC101356558 LOC101346063 LOC101346063 LOC101359819 LOC101359819 LOC101352985 LOC101352985 LOC101350981 LOC101350981 LOC101353247 LOC101353247 LOC101356813 LOC101356813 LOC101340309 LOC101340309 LOC101341590 LOC101341590 LOC101356055 LOC101356055 LOC101340566 LOC101340566 LOC101358072 LOC101358072 LOC101351695 LOC101351695 LOC101359381 LOC101359381 LOC101360338 LOC101360338 LOC101348780 LOC101348780 LOC101347357 LOC101347357 LOC101342268 LOC101342268 LOC101349039 LOC101349039 LOC101349720 LOC101349720 LOC101343363 LOC101343363 LOC101341174 LOC101341174 LOC101355465 LOC101355465 LOC101354778 LOC101354778 LOC101359745 LOC101359745 LOC101358337 LOC101358337 LOC101347198 LOC101347198 LOC101350086 LOC101350086 LOC101352480 LOC101352480 LOC101350333 LOC101350333 LOC101353683 LOC101353683 LOC101352142 LOC101352142 LOC101357741 LOC101357741 LOC101359307 LOC101359307 LOC101354617 LOC101354617 LOC101352570 LOC101352570 LOC101342536 LOC101342536 LOC101353946 LOC101353946 LOC101354459 LOC101354459 LOC101352672 LOC101352672 LOC101343817 LOC101343817 LOC101342214 LOC101342214 LOC101346801 LOC101346801 LOC101358109 LOC101358109 LOC101349753 LOC101349753 LOC101360113 LOC101360113 LOC101357857 LOC101357857 LOC101346027 LOC101346027 LOC101351734 LOC101351734 LOC101348240 LOC101348240 LOC101356948 LOC101356948 LOC101352970 LOC101352970 LOC101343251 LOC101343251 LOC101342555 LOC101342555 LOC101360676 LOC101360676 LOC101344236 LOC101344236 LOC101356848 LOC101356848 LOC101352216 LOC101352216 LOC101340315 LOC101340315 LOC101344772 LOC101344772 LOC101343546 LOC101343546 LOC101354885 LOC101354885 LOC101346784 LOC101346784 LOC101357195 LOC101357195 LOC101355167 LOC101355167 LOC101348995 LOC101348995 LOC101357446 LOC101357446 LOC101348409 LOC101348409 LOC101355316 LOC101355316 LOC101349182 LOC101349182 LOC101355926 LOC101355926 LOC101361049 LOC101361049 LOC101350122 LOC101350122 LOC101358905 LOC101358905 LOC101345959 LOC101345959 LOC101340624 LOC101340624 LOC101358479 LOC101358479 LOC101353387 LOC101353387 LOC101358649 LOC101358649 LOC101349444 LOC101349444 LOC101345104 LOC101345104 LOC101352355 LOC101352355 LOC101352779 LOC101352779 LOC101344856 LOC101344856 LOC101350676 LOC101350676 LOC101345961 LOC101345961 LOC101348251 LOC101348251 LOC101344292 LOC101344292 LOC101358570 LOC101358570 LOC101342738 LOC101342738 LOC101348260 LOC101348260 LOC101360420 LOC101360420 LOC101355969 LOC101355969 LOC101355276 LOC101355276 LOC101356974 LOC101356974 LOC101342682 LOC101342682 LOC101356054 LOC101356054 LOC101341927 LOC101341927 LOC101352293 LOC101352293 LOC101356476 LOC101356476 LOC101361190 LOC101361190 LOC101361359 LOC101361359 LOC101340649 LOC101340649 LOC101352801 LOC101352801 LOC101350576 LOC101350576 LOC101342873 LOC101342873 LOC101355481 LOC101355481 LOC101354547 LOC101354547 LOC101346957 LOC101346957 LOC101357079 LOC101357079 LOC101351810 LOC101351810 LOC101354367 LOC101354367 LOC101356504 LOC101356504 LOC101360881 LOC101360881 LOC101354297 LOC101354297 LOC101360103 LOC101360103
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101356840Transforming protein RhoA. (193 aa)
LOC101357085Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2179 aa)
LOC101355396Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1. (1404 aa)
LOC101345929Ezrin. (586 aa)
LOC101347717Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
LOC101346612Mitogen-activated protein kinase kinase kinase 5 isoform X1. (1374 aa)
LOC101361653Transcription factor AP-1; Belongs to the bZIP family. (329 aa)
LOC101360368Non-specific serine/threonine protein kinase. (552 aa)
LOC101342638cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (398 aa)
LOC101349247Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
LOC101346277Myosin regulatory light polypeptide 9. (172 aa)
LOC101357856Partitioning defective 6 homolog beta isoform X1. (371 aa)
LOC101359687Alpha-actinin-1 isoform X3. (914 aa)
LOC101357690Partitioning defective 6 homolog alpha isoform X2. (344 aa)
LOC101347064Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
LOC101349513Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (231 aa)
LOC101349430Blood vessel epicardial substance. (360 aa)
LOC101341147Myosin-11 isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1979 aa)
LOC101361504Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa)
LOC101361759Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (221 aa)
LOC101347833Hematopoietic lineage cell-specific protein. (498 aa)
LOC101340810Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (360 aa)
LOC101355948Ras-related protein Rab-8B. (207 aa)
LOC101344372Actin, cytoplasmic 2. (375 aa)
LOC101343767Actin-related protein 3 isoform X1; Belongs to the actin family. (418 aa)
LOC101358927Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
LOC101350966Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
LOC1013414805'-AMP-activated protein kinase subunit gamma-3. (500 aa)
LOC101361943Cell division control protein 42 homolog isoform X1. (191 aa)
LOC101345888MAGUK p55 subfamily member 4; Belongs to the MAGUK family. (635 aa)
LOC101346746Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (435 aa)
LOC101352716Protein crumbs homolog 3. (127 aa)
LOC101354844Receptor protein-tyrosine kinase. (1254 aa)
LOC101354514Serine/threonine-protein kinase STK11; Belongs to the protein kinase superfamily. (439 aa)
LOC101351770Myosin regulatory light chain 2, ventricular/cardiac muscle isoform. (147 aa)
LOC101342844Tight junction protein ZO-3; Belongs to the MAGUK family. (918 aa)
LOC101353246Junctional adhesion molecule C. (328 aa)
LOC101356558Ras-related protein Rap-2c isoform X1. (183 aa)
LOC101346063Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (230 aa)
LOC101359819Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (406 aa)
LOC101352985Myosin light polypeptide 6. (151 aa)
LOC101350981Y-box-binding protein 3-like. (267 aa)
LOC101353247Myosin light chain 6B. (215 aa)
LOC101356813Disks large homolog 3 isoform X1; Belongs to the MAGUK family. (817 aa)
LOC101340309Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
LOC101341590Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
LOC101356055Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa)
LOC101340566Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
LOC101358072Symplekin. (1278 aa)
LOC101351695Angiomotin-like protein 2 isoform X1. (778 aa)
LOC101359381Moesin. (577 aa)
LOC101360338Myosin-14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2038 aa)
LOC101348780Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (307 aa)
LOC101347357Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (589 aa)
LOC101342268Radixin isoform X2. (604 aa)
LOC101349039Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
LOC101349720Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
LOC101343363Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa)
LOC101341174Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (288 aa)
LOC101355465Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa)
LOC101354778Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (597 aa)
LOC101359745G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
LOC101358337Serine/threonine-protein phosphatase. (309 aa)
LOC101347198Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (509 aa)
LOC101350086Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
LOC101352480Disks large homolog 2 isoform X1. (975 aa)
LOC101350333Serine/threonine-protein phosphatase. (309 aa)
LOC101353683Ras-related protein Rab-8A. (207 aa)
LOC101352142Heat shock 70 kDa protein 4 isoform X1. (840 aa)
LOC101357741Synaptopodin isoform X1. (939 aa)
LOC101359307Rap guanine nucleotide exchange factor 6 isoform X1. (1604 aa)
LOC101354617Partitioning defective 6 homolog gamma. (383 aa)
LOC101352570T-lymphoma invasion and metastasis-inducing protein 1 isoform X1. (1591 aa)
LOC101342536Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (239 aa)
LOC101353946Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (415 aa)
LOC101354459Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (415 aa)
LOC1013526725'-AMP-activated protein kinase subunit gamma-1 isoform X1. (331 aa)
LOC101343817Ras-related protein Rab-13. (203 aa)
LOC101342214Cingulin. (1195 aa)
LOC101346801Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1491 aa)
LOC101358109Protein crumbs homolog 3-like. (121 aa)
LOC101349753Myosin regulatory light polypeptide 9. (172 aa)
LOC101360113Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (236 aa)
LOC101357857Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
LOC101346027Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (406 aa)
LOC101351734Mitogen-activated protein kinase. (464 aa)
LOC101348240Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa)
LOC101356948T-cell surface glycoprotein CD1b isoform X1. (332 aa)
LOC101352970LOW QUALITY PROTEIN: putative claudin-25. (246 aa)
LOC101343251Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (252 aa)
LOC101342555Tyrosine-protein kinase. (542 aa)
LOC101360676Rho guanine nucleotide exchange factor 18. (1400 aa)
LOC101344236Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X5. (694 aa)
LOC101356848Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa)
LOC101352216Src substrate cortactin. (558 aa)
LOC101340315Transcription factor GATA-4 isoform X1. (443 aa)
LOC101344772T-cell surface glycoprotein CD1a-like. (186 aa)
LOC101343546Mitogen-activated protein kinase. (427 aa)
LOC101354885Tubulin alpha-1A chain-like; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (420 aa)
LOC101346784Non-specific serine/threonine protein kinase. (565 aa)
LOC101357195LOW QUALITY PROTEIN: T-cell surface glycoprotein CD1c. (328 aa)
LOC101355167T-cell surface glycoprotein CD1e, membrane-associated isoform X1. (389 aa)
LOC101348995cAMP-dependent protein kinase catalytic subunit alpha. (293 aa)
LOC101357446LOW QUALITY PROTEIN: T-cell surface glycoprotein CD1b-like. (237 aa)
LOC101348409Band 4.1-like protein 4B. (750 aa)
LOC101355316WASP homolog-associated protein with actin, membranes and microtubules. (717 aa)
LOC1013491825'-AMP-activated protein kinase subunit gamma-2 isoform X1. (574 aa)
LOC101355926MAGUK p55 subfamily member 5; Belongs to the MAGUK family. (675 aa)
LOC101361049Afadin. (1851 aa)
LOC101350122Tight junction protein ZO-1 isoform X1; Belongs to the MAGUK family. (1751 aa)
LOC101358905Junctional adhesion molecule A. (298 aa)
LOC101345959Rho-associated protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1405 aa)
LOC101340624Actin-related protein 3B isoform X3; Belongs to the actin family. (418 aa)
LOC101358479Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (304 aa)
LOC101353387Disks large homolog 1 isoform X1; Belongs to the MAGUK family. (927 aa)
LOC101358649Junctional adhesion molecule B. (460 aa)
LOC101349444Tight junction protein ZO-2 isoform X1; Belongs to the MAGUK family. (1211 aa)
LOC101345104MARVEL domain-containing protein 2. (559 aa)
LOC101352355Myosin-9 isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1969 aa)
LOC101352779Lethal(2) giant larvae protein homolog 2. (1133 aa)
LOC101344856Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (521 aa)
LOC101350676inaD-like protein. (1848 aa)
LOC101345961E3 ubiquitin-protein ligase. (929 aa)
LOC101348251Cingulin-like protein 1 isoform X1. (1305 aa)
LOC101344292Myosin-10 isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1986 aa)
LOC101358570Rho GTPase-activating protein 17. (762 aa)
LOC101342738Multiple PDZ domain protein isoform X1. (2078 aa)
LOC101348260wiskott-Aldrich syndrome protein isoform X1. (534 aa)
LOC101360420Tight junction-associated protein 1 isoform X1. (558 aa)
LOC101355969Angiomotin. (1086 aa)
LOC101355276Cyclin-dependent kinase 4 isoform X1; Belongs to the protein kinase superfamily. (381 aa)
LOC101356974Merlin isoform X3. (622 aa)
LOC101342682E3 ubiquitin-protein ligase NEDD4-like isoform X1. (962 aa)
LOC101356054Ras-related C3 botulinum toxin substrate 1. (148 aa)
LOC101341927Vasodilator-stimulated phosphoprotein isoform X1; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (381 aa)
LOC101352293Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (453 aa)
LOC1013564765'-AMP-activated protein kinase subunit beta-2 isoform X1. (282 aa)
LOC101361190Mitogen-activated protein kinase kinase kinase 1 isoform X1. (1454 aa)
LOC1013613595'-AMP-activated protein kinase subunit beta-1 isoform X1. (271 aa)
LOC101340649Rap guanine nucleotide exchange factor 2 isoform X2. (1678 aa)
LOC101352801Ras-related protein Rap-1A. (184 aa)
LOC101350576Lethal(2) giant larvae protein homolog 1 isoform X1. (1017 aa)
LOC101342873Angiomotin-like protein 1. (869 aa)
LOC101355481Partitioning defective 3 homolog isoform X1. (1323 aa)
LOC101354547Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
LOC101346957Rho guanine nucleotide exchange factor 2 isoform X1. (1015 aa)
LOC101357079Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (466 aa)
LOC101351810Alpha-actinin-4. (876 aa)
LOC101354367MICAL-like protein 2. (908 aa)
LOC101356504Protein scribble homolog isoform X1. (1638 aa)
LOC101360881Integrin beta; Belongs to the integrin beta chain family. (832 aa)
LOC101354297Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (489 aa)
LOC101360103Immunoglobulin superfamily member 5. (411 aa)
Your Current Organism:
Trichechus manatus
NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris
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