STRINGSTRING
LOC101341952 LOC101341952 LOC101357085 LOC101357085 LOC101345326 LOC101345326 LOC101342638 LOC101342638 LOC101348142 LOC101348142 LOC101357016 LOC101357016 LOC101351830 LOC101351830 LOC101357613 LOC101357613 LOC101357541 LOC101357541 LOC101350704 LOC101350704 LOC101344705 LOC101344705 LOC101351136 LOC101351136 LOC101356454 LOC101356454 LOC101353799 LOC101353799 LOC101345870 LOC101345870 LOC101348250 LOC101348250 LOC101355341 LOC101355341 LOC101354503 LOC101354503 LOC101358750 LOC101358750 LOC101349290 LOC101349290 LOC101341082 LOC101341082 LOC101342004 LOC101342004 LOC101345464 LOC101345464 LOC101347686 LOC101347686 LOC101360334 LOC101360334 LOC101353504 LOC101353504 LOC101360945 LOC101360945 LOC101343271 LOC101343271 LOC101358855 LOC101358855 LOC101351254 LOC101351254 LOC101348280 LOC101348280 LOC101358510 LOC101358510 LOC101360343 LOC101360343 LOC101354195 LOC101354195 LOC101357819 LOC101357819 LOC101352296 LOC101352296 LOC101342942 LOC101342942 LOC101342107 LOC101342107 LOC101355469 LOC101355469 LOC101359224 LOC101359224 LOC101347453 LOC101347453 LOC101353435 LOC101353435 LOC101354868 LOC101354868 LOC101342034 LOC101342034 LOC101353775 LOC101353775 LOC101340589 LOC101340589 LOC101353082 LOC101353082 LOC101341777 LOC101341777 LOC101355136 LOC101355136 LOC101345319 LOC101345319 LOC101340402 LOC101340402 LOC101349243 LOC101349243 LOC101346092 LOC101346092 LOC101359245 LOC101359245 LOC101354392 LOC101354392 LOC101356093 LOC101356093 LOC101350438 LOC101350438 LOC101349517 LOC101349517 LOC101350227 LOC101350227 LOC101358487 LOC101358487 LOC101358846 LOC101358846 LOC101361121 LOC101361121 LOC101341327 LOC101341327 LOC101347250 LOC101347250 LOC101359111 LOC101359111 LOC101361837 LOC101361837 LOC101344270 LOC101344270 LOC111819060 LOC111819060 LOC101348995 LOC101348995 LOC101352593 LOC101352593 LOC101346209 LOC101346209 LOC111819711 LOC111819711 LOC101346473 LOC101346473 LOC101341715 LOC101341715 LOC101351188 LOC101351188 LOC101347750 LOC101347750 LOC101344111 LOC101344111 LOC101346041 LOC101346041 LOC101356881 LOC101356881 LOC101360148 LOC101360148 LOC101347845 LOC101347845 LOC111821467 LOC111821467 LOC101351856 LOC101351856 LOC101346534 LOC101346534 LOC101349967 LOC101349967 LOC101361961 LOC101361961 LOC101344242 LOC101344242 LOC101347126 LOC101347126 LOC101346080 LOC101346080 LOC101350742 LOC101350742 LOC101344143 LOC101344143 LOC101361375 LOC101361375 LOC101346076 LOC101346076 LOC101347192 LOC101347192 LOC101358526 LOC101358526 LOC101351543 LOC101351543 LOC101346172 LOC101346172
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101341952Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform X1. (355 aa)
LOC101357085Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2179 aa)
LOC101345326Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
LOC101342638cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (398 aa)
LOC101348142Neuroendocrine secretory protein 55. (248 aa)
LOC101357016Proto-oncogene c-Fos. (380 aa)
LOC101351830Glutamate receptor 1 isoform X2. (906 aa)
LOC101357613Guanine nucleotide-binding protein G(O) subunit alpha isoform X1. (354 aa)
LOC101357541Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
LOC101350704Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
LOC101344705Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
LOC101351136Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
LOC101356454Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
LOC101353799Glutamate receptor ionotropic, NMDA 2A isoform X1. (1464 aa)
LOC101345870Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2178 aa)
LOC101348250Protein kinase C alpha type isoform X2. (549 aa)
LOC101355341Glutamate receptor ionotropic, NMDA 2C. (1156 aa)
LOC101354503G protein-activated inward rectifier potassium channel 1 isoform X1. (501 aa)
LOC101358750Ribosomal protein S6 kinase. (801 aa)
LOC101349290Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1144 aa)
LOC101341082G protein-activated inward rectifier potassium channel 4. (419 aa)
LOC101342004Nitric oxide synthase; Produces nitric oxide (NO). (1434 aa)
LOC101345464Glutamate receptor 3 isoform X1. (894 aa)
LOC101347686Ryanodine receptor 3. (4875 aa)
LOC101360334Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (977 aa)
LOC101353504Dexamethasone-induced Ras-related protein 1. (280 aa)
LOC101360945Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2109 aa)
LOC101343271Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
LOC101358855Glutamate receptor 2 isoform X1. (940 aa)
LOC101351254Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
LOC101348280Guanine nucleotide-binding protein subunit beta-4. (340 aa)
LOC101358510Glutamate receptor ionotropic, NMDA 2D. (943 aa)
LOC101360343Guanylate cyclase soluble subunit alpha-2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (730 aa)
LOC101354195Glutamate receptor 4. (814 aa)
LOC101357819Guanylate cyclase soluble subunit alpha-3 isoform X1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
LOC1013522961-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
LOC101342942Melatonin receptor type 1A; Belongs to the G-protein coupled receptor 1 family. (411 aa)
LOC101342107Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
LOC101355469Adenylate cyclase type 10 isoform X1. (1609 aa)
LOC101359224Calcium/calmodulin-dependent protein kinase type II subunit alpha; Belongs to the protein kinase superfamily. (486 aa)
LOC101347453Pituitary adenylate cyclase-activating polypeptide type I receptor isoform X1; Belongs to the G-protein coupled receptor 2 family. (497 aa)
LOC101353435Calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1; Belongs to the protein kinase superfamily. (499 aa)
LOC101354868Adenylate cyclase type 1. (903 aa)
LOC101342034Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
LOC101353775Uncharacterized protein C1orf226 homolog isoform X1. (694 aa)
LOC101340589Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (377 aa)
LOC101353082Calcium/calmodulin-dependent protein kinase type II subunit beta. (655 aa)
LOC101341777Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
LOC101355136Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
LOC101345319Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
LOC101340402Glutamate receptor ionotropic, NMDA 2B. (1481 aa)
LOC101349243Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
LOC101346092Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
LOC101359245G protein-activated inward rectifier potassium channel 2. (423 aa)
LOC101354392Inositol 1,4,5-trisphosphate receptor type 3. (2670 aa)
LOC101356093G protein-activated inward rectifier potassium channel 3. (393 aa)
LOC101350438Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1076 aa)
LOC101349517Glutamate receptor ionotropic, NMDA 1 isoform X1. (943 aa)
LOC101350227LOW QUALITY PROTEIN: melatonin receptor type 1B. (308 aa)
LOC101358487Calmodulin; Belongs to the calmodulin family. (113 aa)
LOC101358846LOW QUALITY PROTEIN: calmodulin-like protein 3; Belongs to the calmodulin family. (148 aa)
LOC101361121LOW QUALITY PROTEIN: calmodulin-like protein 6. (188 aa)
LOC101341327Guanine nucleotide-binding protein subunit beta-5. (353 aa)
LOC101347250Guanylate cyclase soluble subunit beta-2-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (602 aa)
LOC101359111Calmodulin-like. (149 aa)
LOC101361837Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (922 aa)
LOC101344270LOW QUALITY PROTEIN: pituitary adenylate cyclase-activating polypeptide. (417 aa)
LOC111819060Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
LOC101348995cAMP-dependent protein kinase catalytic subunit alpha. (293 aa)
LOC101352593Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (119 aa)
LOC101346209Ryanodine receptor 2. (5041 aa)
LOC111819711Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
LOC101346473Calmodulin-like protein 4. (153 aa)
LOC101341715Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1079 aa)
LOC101351188Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
LOC101347750Period circadian protein homolog 1 isoform X1. (1299 aa)
LOC101344111Voltage-dependent T-type calcium channel subunit alpha-1H. (2355 aa)
LOC101346041Adenylate cyclase type 5. (1265 aa)
LOC101356881Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
LOC101360148Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
LOC101347845Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 isoform X1. (112 aa)
LOC111821467Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
LOC101351856Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2379 aa)
LOC101346534Inositol 1,4,5-trisphosphate receptor type 1. (2715 aa)
LOC101349967Phosphoinositide phospholipase C. (909 aa)
LOC101361961Calcium/calmodulin-dependent protein kinase type II subunit gamma. (821 aa)
LOC1013442421-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1226 aa)
LOC101347126Calmodulin-2 isoform X1; Belongs to the calmodulin family. (153 aa)
LOC101346080Period circadian protein homolog 3. (1150 aa)
LOC101350742Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
LOC101344143Guanylate cyclase soluble subunit beta-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (614 aa)
LOC1013613751-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1166 aa)
LOC101346076cGMP-dependent protein kinase. (762 aa)
LOC101347192Guanine nucleotide-binding protein G(Q) subunit alpha isoform X3. (381 aa)
LOC101358526Mitogen-activated protein kinase 1. (263 aa)
LOC101351543Ryanodine receptor 1. (4842 aa)
LOC101346172Period circadian protein homolog 2. (1295 aa)
Your Current Organism:
Trichechus manatus
NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris
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