STRINGSTRING
LOC101341952 LOC101341952 LOC101357085 LOC101357085 LOC101345326 LOC101345326 LOC101342638 LOC101342638 LOC101355489 LOC101355489 LOC101342899 LOC101342899 LOC101341626 LOC101341626 LOC101357016 LOC101357016 LOC101357613 LOC101357613 LOC101351035 LOC101351035 LOC101350783 LOC101350783 LOC101347897 LOC101347897 LOC101357541 LOC101357541 LOC101350704 LOC101350704 LOC101344705 LOC101344705 LOC101351136 LOC101351136 LOC101356454 LOC101356454 LOC101361333 LOC101361333 LOC101340366 LOC101340366 LOC101345357 LOC101345357 LOC101348250 LOC101348250 LOC101343591 LOC101343591 LOC101347746 LOC101347746 LOC101343332 LOC101343332 LOC101354503 LOC101354503 LOC101343945 LOC101343945 LOC101349109 LOC101349109 LOC101340818 LOC101340818 LOC101343253 LOC101343253 LOC101360493 LOC101360493 LOC101349290 LOC101349290 LOC101345798 LOC101345798 LOC101345890 LOC101345890 LOC101355964 LOC101355964 LOC101347007 LOC101347007 LOC101344230 LOC101344230 LOC101361367 LOC101361367 LOC101360334 LOC101360334 LOC101358244 LOC101358244 LOC101360945 LOC101360945 LOC101343271 LOC101343271 LOC101361447 LOC101361447 LOC101349646 LOC101349646 LOC101351254 LOC101351254 LOC101348280 LOC101348280 LOC101352902 LOC101352902 LOC101352296 LOC101352296 LOC101349137 LOC101349137 LOC101342107 LOC101342107 LOC101347525 LOC101347525 LOC101360696 LOC101360696 LOC101359224 LOC101359224 LOC101346849 LOC101346849 LOC101343804 LOC101343804 LOC101353435 LOC101353435 LOC101354868 LOC101354868 LOC101342034 LOC101342034 LOC101347790 LOC101347790 LOC101340589 LOC101340589 LOC101353082 LOC101353082 LOC101341777 LOC101341777 LOC101355136 LOC101355136 LOC101345157 LOC101345157 LOC101345319 LOC101345319 LOC101347293 LOC101347293 LOC101356262 LOC101356262 LOC101346694 LOC101346694 LOC101349243 LOC101349243 LOC101344076 LOC101344076 LOC101360281 LOC101360281 LOC101346092 LOC101346092 LOC101341783 LOC101341783 LOC101344337 LOC101344337 LOC101359245 LOC101359245 LOC101354392 LOC101354392 LOC101358981 LOC101358981 LOC101350438 LOC101350438 LOC101351661 LOC101351661 LOC101356099 LOC101356099 LOC101341327 LOC101341327 LOC111819060 LOC111819060 LOC101348995 LOC101348995 LOC101341628 LOC101341628 LOC101352593 LOC101352593 LOC101342804 LOC101342804 LOC111819711 LOC111819711 LOC101354918 LOC101354918 LOC101341715 LOC101341715 LOC101343689 LOC101343689 LOC101352607 LOC101352607 LOC101350197 LOC101350197 LOC101351188 LOC101351188 LOC101346041 LOC101346041 LOC101352786 LOC101352786 LOC101356881 LOC101356881 LOC101360148 LOC101360148 LOC101347845 LOC101347845 LOC111821467 LOC111821467 LOC101355453 LOC101355453 LOC101358678 LOC101358678 LOC101346534 LOC101346534 LOC101349967 LOC101349967 LOC101361961 LOC101361961 LOC101344242 LOC101344242 LOC101354532 LOC101354532 LOC101359658 LOC101359658 LOC101350742 LOC101350742 LOC101361375 LOC101361375 LOC101347192 LOC101347192 LOC101356404 LOC101356404 LOC101358526 LOC101358526
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101341952Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform X1. (355 aa)
LOC101357085Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2179 aa)
LOC101345326Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
LOC101342638cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (398 aa)
LOC101355489High affinity choline transporter 1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (580 aa)
LOC101342899Neuronal acetylcholine receptor subunit alpha-4 isoform X1. (613 aa)
LOC101341626Potassium voltage-gated channel subfamily KQT member 2 isoform X1; Belongs to the potassium channel family. (869 aa)
LOC101357016Proto-oncogene c-Fos. (380 aa)
LOC101357613Guanine nucleotide-binding protein G(O) subunit alpha isoform X1. (354 aa)
LOC101351035Phosphatidylinositol 3-kinase regulatory subunit gamma. (462 aa)
LOC101350783Potassium voltage-gated channel subfamily KQT member 4; Belongs to the potassium channel family. (554 aa)
LOC101347897Neuronal acetylcholine receptor subunit alpha-7. (502 aa)
LOC101357541Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
LOC101350704Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
LOC101344705Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
LOC101351136Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
LOC101356454Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
LOC101361333Potassium voltage-gated channel subfamily KQT member 3; Belongs to the potassium channel family. (843 aa)
LOC101340366Inward rectifier potassium channel 4. (444 aa)
LOC101345357Cyclic AMP-dependent transcription factor ATF-4. (352 aa)
LOC101348250Protein kinase C alpha type isoform X2. (549 aa)
LOC101343591Inward rectifier potassium channel 2. (427 aa)
LOC101347746Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
LOC101343332Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
LOC101354503G protein-activated inward rectifier potassium channel 1 isoform X1. (501 aa)
LOC101343945Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1872 aa)
LOC101349109Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (618 aa)
LOC101340818Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1975 aa)
LOC101343253Calcium/calmodulin-dependent protein kinase type IV isoform X3; Belongs to the protein kinase superfamily. (472 aa)
LOC101360493Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
LOC101349290Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1144 aa)
LOC101345798Cyclic AMP-responsive element-binding protein 5 isoform X1. (508 aa)
LOC101345890Guanine nucleotide-binding protein subunit alpha-11. (354 aa)
LOC101355964Cyclic AMP-responsive element-binding protein 3-like protein 3. (483 aa)
LOC101347007Apoptosis regulator Bcl-2 isoform X1. (229 aa)
LOC101344230GTPase NRas isoform X1. (189 aa)
LOC101361367Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (532 aa)
LOC101360334Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (977 aa)
LOC101358244ATP-sensitive inward rectifier potassium channel 14. (421 aa)
LOC101360945Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2109 aa)
LOC101343271Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
LOC101361447Potassium voltage-gated channel subfamily KQT member 5. (921 aa)
LOC101349646Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
LOC101351254Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
LOC101348280Guanine nucleotide-binding protein subunit beta-4. (340 aa)
LOC101352902Neuronal acetylcholine receptor subunit alpha-6 isoform X1. (494 aa)
LOC1013522961-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
LOC101349137Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
LOC101342107Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
LOC101347525GTPase KRas isoform X3. (227 aa)
LOC101360696Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (460 aa)
LOC101359224Calcium/calmodulin-dependent protein kinase type II subunit alpha; Belongs to the protein kinase superfamily. (486 aa)
LOC101346849Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC101343804Phosphatidylinositol 3-kinase regulatory subunit beta. (729 aa)
LOC101353435Calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1; Belongs to the protein kinase superfamily. (499 aa)
LOC101354868Adenylate cyclase type 1. (903 aa)
LOC101342034Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
LOC101347790Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (614 aa)
LOC101340589Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (377 aa)
LOC101353082Calcium/calmodulin-dependent protein kinase type II subunit beta. (655 aa)
LOC101341777Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
LOC101355136Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
LOC101345157Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (478 aa)
LOC101345319Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
LOC101347293Choline O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family. (620 aa)
LOC101356262Neuronal acetylcholine receptor subunit beta-4. (493 aa)
LOC101346694Neuronal acetylcholine receptor subunit alpha-3. (438 aa)
LOC101349243Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
LOC101344076Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa)
LOC101360281Neuronal acetylcholine receptor subunit beta-2. (500 aa)
LOC101346092Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
LOC101341783Vesicular acetylcholine transporter. (532 aa)
LOC101344337Cyclic AMP-responsive element-binding protein 3-like protein 4. (395 aa)
LOC101359245G protein-activated inward rectifier potassium channel 2. (423 aa)
LOC101354392Inositol 1,4,5-trisphosphate receptor type 3. (2670 aa)
LOC101358981Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (1203 aa)
LOC101350438Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1076 aa)
LOC101351661Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2202 aa)
LOC101356099Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
LOC101341327Guanine nucleotide-binding protein subunit beta-5. (353 aa)
LOC111819060Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
LOC101348995cAMP-dependent protein kinase catalytic subunit alpha. (293 aa)
LOC101341628Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2091 aa)
LOC101352593Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (119 aa)
LOC101342804GTPase HRas isoform X1. (189 aa)
LOC111819711Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
LOC101354918Tyrosine-protein kinase. (1106 aa)
LOC101341715Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1079 aa)
LOC101343689Phosphoinositide 3-kinase regulatory subunit 5. (875 aa)
LOC101352607Cyclic AMP-responsive element-binding protein 3. (377 aa)
LOC101350197Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (393 aa)
LOC101351188Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
LOC101346041Adenylate cyclase type 5. (1265 aa)
LOC101352786Phosphoinositide 3-kinase regulatory subunit 6. (422 aa)
LOC101356881Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
LOC101360148Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
LOC101347845Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 isoform X1. (112 aa)
LOC111821467Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
LOC101355453ATP-sensitive inward rectifier potassium channel 12. (435 aa)
LOC101358678Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1082 aa)
LOC101346534Inositol 1,4,5-trisphosphate receptor type 1. (2715 aa)
LOC101349967Phosphoinositide phospholipase C. (909 aa)
LOC101361961Calcium/calmodulin-dependent protein kinase type II subunit gamma. (821 aa)
LOC1013442421-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1226 aa)
LOC101354532Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1102 aa)
LOC101359658Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
LOC101350742Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
LOC1013613751-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1166 aa)
LOC101347192Guanine nucleotide-binding protein G(Q) subunit alpha isoform X3. (381 aa)
LOC101356404Inositol 1,4,5-trisphosphate receptor type 2. (2441 aa)
LOC101358526Mitogen-activated protein kinase 1. (263 aa)
Your Current Organism:
Trichechus manatus
NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris
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